Rehberg murwere yokuenzanisira anopa mumwe anoverengeka sposobobov, mazano nachiremba

Kana uchifungidzira kuti vamwe chirwere chiremba vakuudzeyi zvekuita kuita pachisara yainzi Rehberg mharidzo. Saka kuziva kunyatsoshanda ropa riyerere kuburikidza neitsvo.

In kugadzirira ongororo Zvinokurudzirwa kwete kuita mumuviri mabasa, uyewo kurega tii, caffeine uye doro. Zvinhu izvi kuchinja mamiriro zviratidzo, uye nyore zvokungwarira kuchaita mufananidzo chaiye zvokunatsa anokwanisa neitsvo.

Paul Rehberg kutanga zvinganaka kumisa mwero filtration ari glomeruli pamusoro exogenous creatinine muna 1926. Muenzaniso Rehberg apo vachiwirirana nevamwe matambudziko. Difficulty chidobi zvaaifanira kusuma exogenous creatinine nomutsinga.

Academician Tareev nyore nzira kuburikidza unoda kuwana nokukurumidza muna 1936

glomerular filtration dziine Clearance (excrete) endogenous creatinine. Ipapo masayendisiti akawana kuti fuma yakawanikwa ropa ari kugara kwazvo. Naizvozvo, nefuma kuti anobaya nomutsinga akazviratidza seisingashandi. Sezvo nzira dzokuziva mwero ropa Clearance ari itsvo pamusoro endogenous creatinine ichinzi sezvo mharidzo Reberga uye - Mharidzo Reberga - Tareeva.

The nzira ongororo yakazokudziridzwa mu dzakasiyana matatu

1. Nzira yokutanga nani anodzidzisa. The nzira anotanga mangwanani apo murwere anopepuka, iye anopiwa kunwa anenge maviri magirazi mvura. Mushure maminitsi 15, anoenda urinate pamusoro chimbuzi nenguva weti kupera rinotaura nguva chaiyo. Murwere anodzoka mubhedha uye chinyararire nhema chaizvo 1 awa uye ipapo weti kupinda mudziyo. Panoperera weti zvakare anonyora nguva chaiyo. Saka akagadzirira 1 achishumira zvinhu ongororo

Murwere riri pamubhedha, uye chaipo 1 awa vanhurume kupinda mudziyo. Saka vakawana 2 chikamu weti.

Reberga vachiongorora unotora zvakabudiswa venous ropa ari chitsama 6-8 Rine mamiririta. Ropa iri kumbokweva pakati muitiro kuisa weti.

Murabhoritari, kuti weti vhoriyamu yakanga akayera mumudziyo mumwe, nhamba iyi rinowanikwa sezvo mvura yabudiswa nokuda itsvo kuti 1 miniti, kweminiti chakarurama inonzi diuresis. Kutsunga nerimwe mharidzo uye plasma creatinine wevasungwa ropa yatorwa. Kugadza Clearance pamusoro endogenous creatinine kushandisa fomura

F1 = (U1 / P) V1.

Saka nhamba Kuwanda creatinine iri weti yasarudzwa mugove wokutanga (U1), yakakamurwa nokuwanda creatine wevasungwa dzakaonekwa mu plasma (P), uye mugumisiro yakakamurwa paminiti diuresis rakatorwa mugove wokutanga weti (V1). Result inotengwa - F1, ndicho chiverengo filtration mwero kuti mugove weti rokutanga.

Chete mukana wokuti vanhu vanga overenga F2, nokuti mugove wechipiri:

F2 = (U2 / P) V2.

Zvinoratidza kuti mashoko vakawana pakutanga uye chechipiri weti yokuenzanisira kusiyana pachavo. Muenzaniso Reberga mune zvimwe zviitiko kuoma ndechokuti nephrotic chirwere kunowedzera excretion kuti creatine ari proximal tubules. Dzimwe nguva chakarurama pathologically secreted creatinine rwomumwoyo tubule epithelium ndiyo 30% izvo nokure kuipa tsika wevasungwa inowanikwa weti,. Izvi zvinoreva kuti kana itsvo murwere hadzishandi zvakanaka, zvakare pasi glomerular filtration vanokwanisa, kuti ongororo zvokurwara haigoni kuratidzwa.

2. Mharidzo Reberga yechipiri musimboti kubatwa nezuva weti vhoriyamu. Murwere anopepuka, wokutanga weti anoita chimbuzi, zororo nguva peeing ari mumudziyo iwoyo, wokupedzisira mugove weveta mangwanani zuva rakatevera. Material akaramba ari firiji pakati micturition. Kana fenzi rinoitwa kumba, shure rokupedzisira weti murwere zviyero zvakarurama Vhoriyamu yose incontinence, rinochengeta mugumisiro Somuenzaniso, zuva diuresis 1100 Rine mamiririta, uremu (murwere) pakati 75 makirogiramu, nekukwirira (murwere) 170 masendimita Ipapo weti yabvongodzwa, chikamu kukandira munhu akaidza. akayera Kuwanda creatinine, uye vamwe kuraswa. Achitaura weti kuti murabhoritari panguva iyoyowo rizowedzerwa ropa. Maererano musimboti yechipiri kuitira kuti aurayiwe Reberga mharidzo. Norma dzinosiyana-siyana zvichienderana nezera uye kuti munhui.

Kana chinoratidza zvasvika munhu azvipire Rine mamiririta 140 / Maminitsi, chiremba ane nokufungirana chokuita kutanga kukura cheshuga, nephrotic urwere, kana BP. Tava kuderera ari excretory renal basa kusvika 50-30 Rine mamiririta / Maminitsi uye pazasi rinoratidza renal kukundikana.

3. Third pachake fenzi zvinhu Reberga mharidzo yakaitwa zvinangwa kwesayenzi uye yakakamurwa 2, uye ipapo 3 zvikamu weti pazuva.