Iyo analoginen "pregna" kushandisa? Tichienzanisa "pregna" zvakafanana

"Pregnil" rinoshandiswa pakurapa anovulatory kushaya mbereko vakadzi, zvinoguma nokupfupfudzika, samoaborta kutyisidzira, uyewo kudzorwa ovarian giperstimulirovaniya, induction kuti ovulation ikawanda inonzi estrogen mumatunhu. kushandiswa kwaro zvinobudirira kuzvitsinhanisa kurapa zano lutein endogenous kemikari kumutsa follicular kuibvisa.

Zvairatidza kuti kushandiswa nevanhu vari kunonoka kuyaruka chokuita hypofunction kwemasero pabonde, cryptorchidism, havachanyatsogoni spermatogenesis. Funga inozivikanwa zvikuru analogue "pregna" munyaya ino.

Description "Pregnil" chinodhaka

"Pregnil" zvinosanganisira chorionic gonadotropin (hCG), munhu. kemikari ichi anotanga kubudisa chorionic zvinyama pakupera embryo muchibereko rikurumidze. HCG ane FSH uye LH basa kunowedzera secretion ose inonzi estrogen uye parura chirongwa ovulation. Naizvozvo hazvina inotsigira dzichipfekeka corpus luteum mbeu basa risati kugadzirwa estrogens uye progesterone placenta.

Kushandisa exogenous kwevanhu chorionic gonadotropin kwete chete runogonesa kuti secretion pamusoro ovarian inonzi estrogen uye progesterone, asiwo induces ovulation, luteal hwezvekukurukurirana unozotevera anobuda follicle.

Kushandisa hCG gadziriro ane kunyatsoshanda mukuru wedunhu nechinangwa dzevanhu kuenda kumwedzi kemikari uye follicle.

regimens

"Pregnil" (analogue "pregna" muenzi panguva iyoyo chipimo chemushonga) anobudiswa panguva dosages ose 1500 uye 5000 MO. Kushandiswa intramuscular jekiseni.

Pakurapa anovulatory kushaya mbereko vakadzi yakarumbidza chete jekiseni 5000-10 000 Ministry of Defense, pamugumo nzira yokurapa pamusoro FSH (follicle nekurukurirano kemikari) kana hMG (human kuenda kumwedzi gonadotropin).

Asati ponji, kudzora ovarian dzishande chinotarisirwa pashure kurapwa 5000 MO.

Tsigirai luteal danho iri kuitwa cyclic jekiseni ari chipimo chemushonga pamusoro 1000 kusvika 3000 MO mazuva ose matatu - ka3.

Men rakashandiswa hypofunction kwemasero dzepabonde uye kutyora spermatogenesis pane mishonga kubva 1000 kusvika 2000 MO kanoverengeka pavhiki (the analogue kuti "pregn" rinogona kutorwa nenzira iyoyo).

Pakurapa cryptorchidism pakushandisa vana zvinodhaka 2 pavhiki, akakurudzira chipimo chemushonga:

- kusvika 2 years - 250 MO;

- kusvika 6 makore kunan'anura 500 kusvika 1000 MO;

- pashure 6 makore - 1500 MO.

Takurukura pokushandisa zano zvinodhaka. Asi kupfuura ose vasati vatanga kurapa bvunza chiremba uye vawane kugadzwa kwaari zvinodhaka.

Analogs "pregna»

Ndezvipi vachigadzirira "Pregnil" dzomuzana? Kutaura zvazviri, vakawanda vavo, pane mishonga isingadhuri, pane zvinodhura.

"Chorionic Gonadotropin"

"Chorionic Gonadotropin" riri rweruzhinji analogue "pregna." Yakabudiswa ari chipimo chemushonga 500; 1000; 1500 ED. It rikashandiswa intramuscularly. Raitongwa ari dose pamusoro 1500 Iu rimwe zuva kana 3000 Iu 2-3 pavhiki pakurapa mbereko vakadzi. In pakurapa pabonde infantilism kugadza 500 kusvika 1000 Iu kamwe pavhiki, makosi kusvika 2 months. Vana kugadza 500-1000 MO makore gumi, ipapo - 1500 Iu kusvika mwedzi zvichimurova mapoka. Kureva zvinodhaka "Pregnil" analogues vari husingakoshi.

"Ovitrel"

"Ovitrel" unotora horiogonadotropin Alpha. Yakabudiswa ari chipimo chemushonga 250 micrograms (6500 Iu). It rikashandiswa subcutaneously. Kunomutsa paumbwe corpus luteum mbeu, follicle kuibvisa uye ovulation. 250 d zvakaenzana 5000 vamapoka kwevanhu chorionic gonadotropin. Pamusoro kweiyi ovarian superovulation uye kugamuchira 250 .mu.g kushandiswa, pashure nzira yokurapa kana munhu kuenda kumwedzi FSH. Pakurapa anovulation ushandiswe dose nokuda 1 zuva asati zvepabonde.

"Horagon"

Imwe analogue "pregna." Available vari chipimo chemushonga pamusoro 1500 uye 5000 MO. Raitongwa intramuscularly. Rinoshandiswa kuti dysmenorrhea, hypoplastic gonads, kurara infantilism kuti mhanyisa kuyaruka, ngozi vaingoerekana pamuviri, kufurira superovulation. Kufurira superovulation raitongwa ari chipimo chemushonga pamusoro 5,000 kusvika 10,000 MO kamwe. In pakurapa vanongogara pamuviri Zvinokurudzirwa kushandisa zuva pakagadzwa pamuviri kutanga kune vhiki 14, kaviri pavhiki 10 000 MO. hypogonadism kurapwa unotora kutungamirira kubva 1,500 kusvika 6,000 MO kamwe pavhiki. Androgen kushayiwa nevanhu kubatwa nokushandiswa HCG 1 ose vhiki mbiri kwemwedzi mitatu.

"Choriomon"

Yakabudiswa ari chipimo chemushonga pamusoro 5000 Iu / Rine mamiririta kuti intramuscular yaitonga. Zviri zvikuru abudirire pakurapa anovulatory zvinogara uye amenorrhoea. Ikashandiswa pamwe kwevanhu kuenda kumwedzi gonadotropin (75 MO) mazuva 10 subcutaneously kana intramuscularly, kuti vawedzere secretion pamusoro estrogens. Kana Ultrasound vakura follicle kuti ovulation induction raitongwa kubva 5000 kusvika 10 000 MO "Choriomon". The mushonga chinotarisirwa mazuva 1-2 mushure wokupedzisira jekiseni FSH kana hMG. Zvepabonde inokurudzirwa zuva nezuva kusvikira ovulation.

Kushaya mbereko nokuda kukwana luteal kutotanga "Choriomon" rinoshandiswa 5000 MO 21, 23 uye mazuva yechi25 ichitanga.

"Profazi"

"Profazi" - zvineringanidzo "pregna 5000". Available vari chipimo chemushonga kwa2000 uye 5000 MO. It rikashandiswa intramuscularly. Zvipatara anovulatory kushaya mbereko iri kuitwa nokusuma 10 000 MT pakati ichitanga, pashure kurapwa pamwe HMG kana FSH. Kufurira superovulation kugadza MO 10000 pazuva kusvika fence zai. Kana corpus luteum mbeu insufficiency yakarumbidza Kutarisirwa MO 5000, uye weshanu zuva wechipfumbamwe pashure ovulation. "Profazi" ndizvo chaizvo nyanzvi pakurapa idzokororo kubva kwepamuviri. Rinoshandiswa 10 000 MO rokutanga chikumbiro, ipapo - on 5000 Defence kaviri pavhiki kusvika vhiki 14.

Contraindications

Contraindications pakushandisa hCG kugadzirira:

- kubereka.

- kemikari-kubereka mapundu dzokubereka mumasero.

- mapundu of hypothalamus uye pituitary shwanu.

- mapundu of dumbu haawirirani pamuviri.

- Thrombophlebitis.

- Hypothyroidism.

- yaTubhari pamuviri nhoroondo kuti matatu asati kurapa mwedzi.

- Polycystic ovary.

- Lactation.

nemishonga

Side migumisiro kubva kushandiswa kwevanhu chorionic gonadotropin:

- kwakawedzera kushatirwa, mupfungwa lability, kutemwa nomusoro, uye kuzvidya mwoyo.

- dyspeptic matambudziko (kuda kurutsa, kurutsa).

- kwakawedzera aikanganiswa kuti minyatso.

- Gynecomastia nevanhu.

- mapundu, mikoko.

- Syndrome pamusoro ovarian hyperstimulation.

- A kwenguva Zvakawanikwa yemukomana, mwero erection.

- rutapudzo of pituitary shwanu.

- rutapudzo kuti achiparadzira bhuku ropa (hypovolemia).

- kuunganidza ropa iri abdominal mhango.

- Thromboembolism.

- Multiple pamuviri.

- Zvinoyerera chengetedzo, akaratidza, zvakafanana edema.

Analogue "pregna 1500" basa iri vakaremara zviri dumbu, uye kusangana nekutsi kwemukadzi zvinoshandiswa, adhesions ari fallopian sepombi, chikuru ovarian kukundikana, fibrotic mapundu guru iri dumbu.

The yose Kurapa anotora nzvimbo zvakasimba pasi nyanzvi kutarisirwa uye kudzora kuchinja pachisara kushandiswa kwezvinodhaka izvi mumba hakubvumidzwi uye kungaita kuti irreparable migumisiro utano.

Mabatirwo anovulatory kushaya mbereko zvinofanira kuitwa pasi Ultrasound kuzvidzora follicle kukura uye kunopfuurira tinyatsonzwisisa remuromo indekisi.

Hunokosha richiona zuva nezuva wevasungwa pakati estradiol. With zviratidzo vasingadiwi ovarian hyperstimulation kurapwa chorionic gonadotropin pakarepo wakagumiswa.

Takurukura kuti mushonga "Pregnil" analogues, nokuti kushandiswa kuti avatungamirire hunorondedzerwawo.