The mushonga "Ksarelto" mirayiridzo yokushandisa senzira maitiro, ndiko anticoagulant zvakananga chiito. In hwaro kwezvinodhaka iri zvakananga chinovhiringidza kuti chinhu Xã. Uyezve, mushonga uyu ane hwakanyatsorwisa yakakwirira selectivity. Kana pharmacokinetics ayo, yava nokukurumidza kunyura, richisvika kunonyanyisa wevasungwa muropa mushure maviri chete mana maawa pashure nomumukanwa yaitonga. Kana isu kutaura pamusoro zvinhu mukuru excretion zvinodhaka, pamwe weti uye mutsvina yadzo vakaratidza vanenge 92-95% mishonga "Ksarelto". Mirayiridzo yokushandisa (mutengo, nenzira, ichi chinomirira anenge 1500 rubles) yakati pano kuti dzasara chinosiya muviri unaltered chimiro ne renal excretion.
Available anticoagulant ichi muchimiro kumativi mahwendefa rima blue kana yakatsvukuruka mashava ruvara, ine zvayo sezvamunoita gumi, gumi kana makumi maviri milligrams kuti micronized rivaroxaban. Upiyona hwebetsero muri zvinhu zvakadai croscarmellose yavaibvisa, yavaibvisa lauryl sulfate, hypromellose 5cP, microcrystalline cellulose, magnesium stearate uye lactose monohydrate. The goko sezvamunoita zvinosanganisira titanium dioxide, Macrogol 3350 uye tsvuku ferric oxide. Uyezve, bhuku duku rine hypromellose 5cP.
Gadzai piritsi "Ksarelto" mirayiridzo kushandiswa kazhinji pachii varwere vanenge kare inini maoparesheni pamusoro rezasi migumo. Nokuti chikamu ichi vanhu anticoagulant chiito sezvo inobudirira yokudzivisa nechiyero neramangwana kukura venous thromboembolism. Mukuwedzera, zvinodhaka "Ksarelto" zvakakwana yakakodzera kudzivirira dzokororo ine DVT uye Pe. Uyewo, chokushandisa ichi inofanira kushandiswa kudzivisa sitiroko mune vanhu vane atrial fibrillation, non-valvular mhando. Kudzivirira kukura systemic thromboembolism uye kurapwa kwakadzama tsinga thrombosis uye rikwanise occlusion pamusoro pulmonary tsinga uyewo rinokurudzira kutora mapiritsi "Ksarelto" mirayiridzo Chinyorwa.
Shandisa anticoagulant iri zvachose contraindicated vanhu vane gastrointestinal, intracranial kana zvimwe mhando ropa, nzara muchimiro itsvo kukundikana kana kusashivirirana kuti galactose. Kana murwere hypersensitivity kuti rivaroxaban kana sema paakasangana nevamwe Excipients akanyorwa murwiyo, uye haafaniri kutora zvinodhaka "Ksarelto". Mirayiridzo dzokushandisa unorambidza amutarire zvakasimba uye panguva yepamuviri. Contraindications vari lactose haanzwisisi, kurapwa nedzimwe anticoagulants, chiropa chirwere, achiperekedzwa coagulopathy, uye mamiriro chokuita yakakwirira mukana zvikuru ropa. Uyezve, haukwanise kutora mushonga vakadzi, ekukurerai, uye vanhu vakanga vasina kuenzana makore gumi nemasere.