Triptans nokuti migraine. Triptans: zvinodhaka mitengo

Migraine - idambudziko varwere vakawanda. Anenge munhu wose kanenge kamwe hwose zvakaitika marwadzo ari musoro. Kazhinji, vari achiperekedzwa dzungu, kuda kurutsa, kurutsa, uyewo chiveve, tingling uye kusimba wamativi, Photo uye phonophobia. Pashure akangokudenha, varwere chokunyunyuta pamusoro kuneta, lethargy uye hope. Dzimwe nguva pane zviitiko kana maperembudzi ndinomhanya saizvozvo kuti anogona kubatsira chete murwere triptans nomusoro. Zvinofanira kucherechedzwa kuti migraine - nechirwere vakadzi, sezvo ivo vari zvikuru kubatwa zvokurwara yakadaro, pane vanhu. Inenge 10-18% vakuru chirwere migraine.

The dambudziko musoro avanoziva nomumwe

Vanhu vakawanda havatsvaki rubatsiro kubva vanokwanisa zvokurapa uye anoedza kutsungirira chirwere, vachitsigira analgesics. Zviri pachena kuti izvozvo nzira asingakubatsiri, asi chete exacerbates chirwere. Kushandiswa kusingadzoreki pamusoro analgesics kunogona kukonzera kukura zvinodhaka nokuda chisingaperi nomusoro. Saka, hazvishamisi kuti pane akawandisa mibvunzo pamusoro kworudzii nomusoro mapiritsi - inonyatsobudirira.

Chose ingapedza migraine hazvibviri, asi kuti kuvandudza upenyu zvinogoneka chaizvo zvigadzirwa, izvo vanogadzwa chiremba wetsinga. Pane dziri anozivikanwa guru chitsama migraine zviri zvakakwana inobudirira zvose panguva akangokudenha, uye mune interictal munguva. Next, tikanyatsoongorora zvinodhaka kuti migraine: mazita zvinhu uye rikwanise kurwisa-isina kurapa. Zvinonzi zvakaratidza kuti triptans - mishonga inonyatsobudirira kubvisa anotemwa nemusoro. With prophylactic zvinodhaka basa zvinotevera mapoka:

• β-blockers;
• antidepressants;
• antiemetic;
• mvura-soluble vhitamini B;
• karusiyamu blockers;
• anticonvulsants.

Kubvuma ose pamusoro semunhu Pharmaceuticals vanofanira kugadza anokwanisa munhu.

Sei kuva nomusoro?

Usati kunzwisisa sei kuita triptans kubva nomusoro, mutengo iyo kunobva mugadziri, zvinokosha kunzwisisa mashandiro ari zvokurwara. Headache hwapedyo nokuda kweiyi receptors pamusoro meninges uye chepfungwa nemidziyo. Kana kunyanyisa Makakatanwa uye izere tsinga, kunyanya mutsinga, riri rimwe hypotonic ezvinhu hwapedyo zvikuru kurwadziwa, izvo zvinogona kubviswa chete pachishandiswa anokosha Pharmaceuticals. Vatsvakurudzi Vazhinji vaitarisira kwenguva refu, achigadzirira Mabatirwo migraine, vakagumisa kuti triptans - yakanakisisa zvinoreva kugadzirisa zvokurwara ichi.

ehupfumi triptans

The zvinodhaka zvainanga kuderedza dilated midziyo uropi. Triptans - mushonga kuti anoita mwoyo uye receptors ari trigeminal etsinga, izvo zvinozoita akazoita aikanganiswa pakati marwadzo pachikumbaridzo. Triptans - ano antimigraine zvinodhaka, vane panzvimbo yakakwirira selectivity kuti ropa midziyo reDhura mai (reDhura mai encephali) uye zviduku uye peripheral uye coronary nemidziyo.

mishonga nechipiriso unoshanda mukuderedza marwadzo panguva ufanane musana musimboti wenyika trigeminal etsinga. Kuwedzera pamusoro zvose triptans ari - mishonga havagoni chete kuderedza kuitika chirwere kuitazve, asi kubvisa zvinenge zvekuchipatara kuratidzwa kwayo (semuenzaniso, kuda kurutsa, kurutsa, photophobia, uye inzwi).

The chikuru zvakanakira triptans

Izvi pharmacological ehupfumi kuti kumhanya vaumbe mugumisiro. Chaizvoizvo hafu yeawa pane zviratidzo Migumisiro yacho zvinodhaka mumuviri murwere. The kuchirapa zvazviri anodzokororwa yose migraine kurwisa. Ruzhinji varwere nomusoro asingadi recur.

Mazuva ano, masayendisiti akaratidza kuti kuziva miedzo Precursors kurwiswa hwobva kutora triptans kuti migraine. Pakuvamba paiva dzidziso kuti migraine kurwisa vanofanira kubatwa mumatanho, kutanga mabiko mishonga nyore.

Zvinodhaka kuti migraine: mazita zvikuru dzakakurumbira mishonga

Mugore triptan boka zvinodhaka inosanganisira zvinotevera:

• 'Zomig'.
• "Amigrenin".
• "Sumatriptan".
• "Imigran".
• "Relpaks".
• "Trimigren".
• "Sumamigren".
• "Rapimed".
• "Almotriptan".
• "Naramig".
• "Naratriptan."
• "Frovatriptan."
• "Zolmitriptan."

Mishonga mumwe murwere kungava tisingatauri woga, saka kuti nechokwadi kubudirira ichi kana mimwe mishonga, vanachiremba vanoti kuedza kuushandisa matatu migraine kurwiswa. boka zvinodhaka Tryptamine kunoratidzwa dzakakwirira bioavailability, vari nyore kukurira ropa-uropi mhinganidzo, unoshanda mukuderedza migraine kurwiswa, kunyange kurwadza chokutambudzika. mishonga izvi zvakakodzera kuti taurira varwere vane mwero kune zvikuru chirwere nekuomarara.

Application Notes

Kazhinji tinonzwa mubvunzo iwoyo: chii nomusoro mapiritsi zviri nani? zvidzidzo zvokuongorora dzakaratidza kuti inonyatsobudirira nzira yokubvisa zviratidzo migraine muri triptans. Zvakanakisisa kutora triptans nokuda migraine kana anoona zviratidzo kurwiswa rokutanga. Kufadza unonyaradza marwadzo kushanda Zvakacherechedzwa kwemaawa maviri pashure achitora mushonga. Asati kutora mushonga, nyatsoverenga mirayiridzo kunoona chiremba. Zvakakosha chaizvo kudzivirira kwezvinodhaka ovhadhozi. Triptans nokuti migraine haisi varumbidzwa kushandisa pamwe nemishonga, antifungal, antiviral vamiririri, uyewo antidepressants.

Kuti awane zvaaida mugumisiro, varwere vanofanira kuomerera zvinotevera nhungamiro pakugamuchira triptans:

• pamwe nounyoro kune mwero nomusoro kutora 1 piritsi (kana mumwe dose pfapfaidzo);
• dose yechipiri vanobviswa kwete kwokutanga pane 2 chasa;
• masikati rega kutora mishonga kupfuura maviri;
• triptans havasi varumbidzwa kutora mazuva anopfuura maviri pavhiki.

Panguva Mabatirwo zvaunodya inofanira kunze tiraminsoderzhaschie Products:

• koko;
• chokoreti;
• bhinzi;
• mazai;
• celery;
• Citrus;
• muviri zvokuwedzera;
• chizi;
• madomasi;
• nzungu;
• nedoro.

Mumwe Ngaaregewo kudya zvokudya chando.

At panowanikwa migraine triptane, mutengo izvo sezvinoratidzwa pazasi, anogonawo kushandiswa nevamwe zvinodhaka, zvakadai metoclopramide kana domperidone.

nemishonga

Kana mushonga ovhadhozi, varwere nezvinotevera nematambudziko:

• dzungu;
• anaphylactic kugwinha;
• tightness;
• svoto;
• ushamwari;
• infarction of chirwatata, ura;
• kurutsa;
• muromo yakaoma;
• myalgia;
• abdominal kurwadziwa;
• hope;
• kutsva manzwiro pamusoro ganda;
• Angioedema;
• tachycardia;
• mikoko;
• polyuria;
• tsandanyama simba;
• ungaderedza nzeve;
• kutsinga dzinouya mabongozozo;
• haemorrhagic manyoka;
• kuita weti kakawanda;
• coronary vasospasm.

Pasinei neizvi zvose, triptans nokuti migraine - mishonga akurumidze-kuita. Subject chipimo chemushonga uye kakawanda kutora zvinodhaka ngozi nemishonga iri shoma. Kazhinji, triptans zvose akashivirira nomuviri zvakanaka. Marwadzo, kana zvaitika, akabva akaratidza munyoro uye kugadzirisa nomuzvarirwo pasina zvokurapa kupindira. The chikuru drawback pamusoro triptans - ndiwo mutengo wavo. Zvinosuruvarisa, kwete varwere vose vanogona kuwana mushonga wakadaro.

Contraindications

Triptans nokuti migraine regai kuvakurudzira kushandisa zvinotevera nyaya:

• Kurohwa;
• angiospastic angina;
• pamuviri;
• cerebrovascular tsaona;
• munguva kuyamwisa mwana;
• coagulopathy (kweropa);
• kuyaruka;
• zvirwere kumwoyo;
• hypersensitivity kuti bioactive zvinokuvadza ari Pfungwa;
• kusingadzoreki neBP;
• arrhythmia;
• chiropa uye chirwere cheitsvo;
• atherosclerosis.

Asati varwere vamwe triptans, ari kupinda chiremba vanofanira kuzivikanwa zvinokonzera ngozi atherosclerosis. Zvinhu izvi zvinosanganisira zvinotevera:

• chirwere cheshuga;
• post-kuenda kumwedzi vakadzi;
• kusvuta;
• neBP;
• kufutisa;
• refu azvipire zvemamiriro ropa remafuta akawandisa;
• zera makore 40 varume;
• majini kubatwa kune chomwoyo.

Vamwe varwere vari pangozi vanofanira kugamuchira dose yavo tryptamine rokutanga pasi pokudzora nyanzvi uye pasi ECG kuzvidzora.

Scheme kurapa migraine

Kune vakawanda Misimboti yokurapwa zvirwere kuti vanoruramiswa kakawanda:

• zvakakodzera kutanga kurapwa pamwe analgesics kana mubatanidzwa yayo (kusanganisira nonsteroidal mishonga Anti-anogumbura);
• Kana marwadzo kushandiswa haripi yakanaka mugumisiro, shure maminitsi 45 vanofanira triptan;
• kana munhu triptan kwave basa, rinotevera kurwisa anofanira kushandisa rimwe mushonga kubva boka triptanovoy;
• pamwe atypical nomusoro zvinokosha kushandisa vasiri steroidal Anti-anogumbura zvinodhaka.

Kushandisa midziyo ano kuti kurapa migraine, akasikwa pachishandiswa triptans, kubatsira kuti upenyu nyore varwere vakawanda. Usakanganwa kuti kutora mishonga izvi zvinogona kupiwa nachiremba, uye kana chete zviratidzo. Pane mamiriro ezvinhu apo triptans uye dzimwe nonspecific analgesics musapa aida mugumisiro uye asingauyi kubvisa marwadzo. Muchiitiko chino, vanachiremba kazhinji mishonga kunzwisisa kurapa pamwe anticonvulsant mishonga, uye Beta-blockers. Mishonga iyi zvinosanganisira zvinotevera zvinodhaka:

• "Penbutolol".
• "Nadolol."
• "Betaxolol."
• "Topiramate".
• "Neurontin."
• "Phenobarbital".
• "Timolol".
• "Propranolol".
• "Labetanol".
• "Bellataminal".
• "Metoprolol".
• "Topamax".
• "Acebutolol".

How kuderedza kuitika kurwiswa?

Kuderedza kakawanda wevarwere migraine vanofanira kuomerera mitemo zvinotevera:

• kudya nguva;
• haabatanidzi kubva zvaunodya zvokudya uye zvinwiwa kuti pave nekukurukurirana kurwisa (doro, chocolate, chizi, Champagne, Citrus zvibereko, waini tsvuku);
• kusvuta;
• sezvo zvinokwanisika kuva panze refu;
• nzvenga kushushikana;
• Exercise (yakanaka - kushambira);
• kudzivisa nzendo refu nebhazi, chikepe, motokari.

Triptans vari nemusoro: mutengo

Triptans anobudiswa dzakasiyana chipimo chemushonga siyana: jekiseni zvinogadzirisa, nasal pfapfaidzo, mapiritsi, rectal suppositories. On mari zvinodhaka kunokanganisa rokusunungura chimiro, chipimo chemushonga, nhamba mapiritsi ari pasuru. Somugumisiro, mari zvinodhaka izvi zvinosiyana munzvimbo zvakawanda - 150-1500 rubles por rongedza.