Interstitial nephritis: zviratidzo uye Mabatirwo itsvo kuzvimba

Interstitsionalny nephritis iri anogumbura cheitsvo, izvo rikauya kazhinji kukanganisa zvenguva zvinyama uye itsvo tubules.

The chirwere chinogona kuitika panguva mishonga kurapwa (more nemishonga, kuti muduku diuretics, sulfonamides) uyewo kana pachena kuti utachiona, nemavhairasi, mune masoja zvirwere. The zvokurwara kunobva lymphohistiocytic infiltration kuita pamusoro zvenguva renal kukuvara rinenge kwakaitika pashure yepasi Kamudzira pamusoro tubules. In chimiro ichi zvirwere zvivako uye autoantibodies kuti Kamudzira mapurotini. Somugumisiro chepfungwa edema uye kuzvimba itsvo rinenge rukoko chinhu zvokuimba compression midziyo ropa uye tubular, akaderedza renal chokubuda ropa, kuwedzera kufurirwa vnutrikanaltsevoy, pakupedzisira anovandudza oliguria.

Apo chirwere pamusoro interstitial nephritis zviratidzo ndeinotevera. Kutanga chirwere - kusachengeteka kukuru, kupfuura fivha, polyuria, kana hematuria hwapedyo itsvo kukundikana, pane kurwadziwa panzvimbo dzapasi shure. Zviratidzo chipimo chemushonga siyana rikwanise rokutanga interstitial nephritis protrude zvakare kuwedzera muviri tembiricha, izvo zvingazivikanwa chokuita eosinophilia uye ganda kwemakomo. Nokuti chirwere dzinoratidzwa mwero proteinuria, hematuria, muna zvisingawanzoitiki kacho, oliguria.

Chenjera interstitial nephritis nemavhairasi siyana kazhinji inoitika pamwe Hemorrhagic Fever uye renal syndrome.

Dambudziko chirwere inoitwa cheitsvo, rikwanise glomerulonephritis. Kana dzichiri itsvo kukundikana anofanira Kwabviswa zvimwe zvinokonzera.

Zvakaoma chaizvo uye dzimwe nguva zvakaoma kuziva chikonzero chisingaperi nephritis tubulointerstitial chokuita zvinodhaka dzokupisa, noutachiona, masoja zvirwere.

Chirwere interstitial nephritis ine muna tubular zvinetso, vakakurumidza kutanga aqueous electrolyte vachivavhiringidza (hyperkalemia, acidosis) Abuse wevasungwa neitsvo. Mune zvisingawanzoitiki kacho zvinoita neBP uye proteinuria. In mureza ezvinhu nephrotic chirwere ndisipo, asi kana chirwere kunoita interstitial nephritis chepakarepo neolichim kuti glomerulonephritis. Mishonga kupfuura ngozi, zvoita kuti chirwere chimiro chirwere vari analgesics phenacetin, analgin, asipurini.

Dzimwe nguva madzimai 35-40 nemakore, migraine, kuora mwoyo, dumbu maronda, akacherechedza unonyaradza marwadzo interstitial nephritis. In ichi chaiwo akabatana aseptic leukocyturia nemishonga renal colic Zvikamu pamwe zvakakomba hematuria, renal kukura rutapudzo, polyuria, kupererwa neropa.

Hosha ikabuda akabatana nevamwe zvirwere, ane yakajeka zvirwere pathogenesis (active chisingaperi chiropa, lupus chinonzi systemic lupus erythematosus).

Interstitial nephritis muvana anogona kukudziridzwa panguva dizembriogeneza renal rinenge Urinary turakiti anomalies, kutyorwa uric asidhi uye calcium yakawanda oxalate muviri.

Kurwisa chirwere anoshandiswa etiological mishonga kwemabhakitiriya maronda dzinotanga kubvisa pfungwa chirwere. Kana chipimo chemushonga fomu - kurega kushandisa zvinodhaka, taurira zvokudya vafumiswa pamwe mavhitaminzi uye kudhakwa. Pasina migumisiro ushandiswe glucocorticoids vanoita hemodialysis, haabatanidzi kushandiswa diuretics kukura chakasimba renal kukundikana. Zvinokoshawo kuti vadzivise zvakawedzera kushandiswa analgesics nokunwa zvakawanda.