Zvinodhaka kuti migraine - triptans. Dosing uye zvinoitwa chiito

Migraine - ichi ndechimwe rakajairika zvirwere, zvinogona kuderedza kunyatsoshanda wevarwere zhinji. chirwere ichi chinobata anenge 6% varume 18% vakadzi. Izvi nhamba dzakakwirira zvikuru. Zvisinei, 60% vanhu vanotambura nechirwere ichi, vakazvimirira kutora analgesics siyana kuti kurwadziwa. Kazhinji, zviito zvakadaro chete sembura weboka chirwere.

Aiwa analgesics

Vanhu vakawanda vanotambudzika kutemwa nemusoro, handizivi sei kurega kurwisa, uye kunonoka kutora inonyaradza marwadzo omusoro. Kubva ichi kurapwa kushanda zvikuru duku. Kana ari vasipo. Izvi zvinokonzera kuti murwere anotanga zvishoma nezvishoma kuwedzera uwandu husingakuvadzi ari kurapwa. Somugumisiro zviito zvakadaro chete zvinowedzera mukana kukuvara itsvo, kukura gastritis. Mune zvimwe zviitiko, analgesics yaunodya kungaita kuti zvikuru nemamwe matambudziko - the kwaita musoro zvinodhaka Kutemeswa.

Ndokusaka kana muine zviratidzo migraine anofanira kureva unyanzvi. Self-mishonga iyi, anogona chete sembura murwere ezvinhu. Mukupera kwezana remakore rechi19 boka zvachose idzva akasikwa antimigraine zvinodhaka - agonists zvokusarudza 5 NT 18 / D-receptors. Zvakadai zvinokuvadza vari nomukaka 5-gidroksitritamina. Rakapfupikiswa zita ravo - triptanity. Zvinodhaka kuti migraine pazera iri zvikuru basa kudarika kwakajairika analgesics. Uyezve, maturusi izvi zvava nyore kune zvose Mapato wevarwere.

Sei zvinodhaka

Triptans - zvikuru yemhando pakurapa chirwere ichi chisingafadzi, migraine. Zvinofungidzirwa kuti zvinodhaka zvose izvi kushanda saizvozvo. Zvisinei, mumwe murwere kunobatsira chete zvishoma vakawanda triptans. Naizvozvo, kwokupedzisira kusarudzwa chigadzirwa ichi anoramba chete chete murwere. Kuti tizive kubudirira imwe triptane, zvakakodzera kuti kuedza mushonga panguva migraine kurwiswa. Kanenge vatatu vavo vaende. Kana mushonga yakabatsira, rinogona kushandiswa mune ramangwana. Chokwadi, kusarudza kunogona kukanganisa zvikuru mari imwe triptan. Pashure pezvose, mishonga izvi hazvisi chisingakoshi. Uyezve, mumwe Pfungwa ane imwe unonyaradza marwadzo maturo. Uyezve, zvinokosha kuziva chii vari triptans kuti migraine, inoti chiito, nzira kugamuchirwa uye contraindications.

Chokutanga, mishonga yakadaro ane simba pamusoro receptors mudziyo pamadziro. somugumisiro Chinokonzera kuderedza dilated chepfungwa midziyo ropa, uyewo kunobatsira kuderedza nomusoro.

gadziriro yakadaro nhaka zvakakwana yakakwirira selectivity. Ndokusaka triptans ine zvainoita midziyo ropa reDhura. Uyu ndomumwe unyanzvi hwavo. Zvisinei, havana zvainoita peripheral uye coronary nemidziyo. Zvinofanira kucherechedzwa kuti triptans - migraine zvinodhaka kuti adzikatidza panowanikwa marwadzo panguva Kanotokonya pamwero, dziri muna musana musimboti wenyika trigeminal etsinga. Izvi kunoderedza aikanganiswa marwadzo zvikuru.

Uyezve, zvinodhaka izvi zvinogona kuderedza kakawanda zvazvo, uyewo zvinobudirira kubvisa zvinenge zviratidzo, zvakadai inzwi uye photophobia, kurutsa uye svoto.

Minda kuitwa triptans

Kuti tinzwisise kuti zvinodhaka izvi chiito, ndiko kupa zvinokosha:

1. Vasoconstriction, iri muuropi.
2. Anti-anogumbura chiito: rutapudzo pamusoro kuzvimba, iyo anoisa vomanikidza etsinga harinzwi.
3. Kudzvinyirirwa manyawi trigeminal tsinga uye kuderedza aikanganiswa aro marwadzo.

Sezvaunogona kuona, triptans nokuti migraine - mishonga inonyatsobudirira anogona kumisa kurwisa chirwere chacho. The chikuru ndechokuti kusarudza zvakanaka zvinodhaka

Zvakanakira nekuipira triptans

Pakati zvakanakira zvigadzirwa zvakadaro ndiko kupa hubudirire utariri kurwadziwa uye aishamwaridzana zviratidzo, chiito. Uyezve triptans inogona kushandiswa kurapa zvirwere zvakasiyana zera mhando.

Chokwadi, chero mushonga une payakaipira. Zvakakwana kubatsira triptans kuti migraine uye nomusoro. Zvisinei, kuti chakarondedzera chiito zvinodhaka izvi haisi aizvinzwisisa. Mukuwedzera, kwete munhu anokwanisa kutora triptans sezvo utano hwavo. Zvinonzi rambidzwa kushandisa zvinodhaka ava vanhu vachitambura nechirwere chomwoyo. In muchikwata ichi ndivo vaya vane ropa clots uye akaipa neBP aripo.

chizvarwa chokutanga

Migraine gadziriro - triptans - conditionally rakakamurwa mapoka akawanda. Uyu ndiwo wekutanga uye rudzi rwechipiri. Mumwe mushonga ine mikana ayo uye nekuipira. Saka, rudzi wokutanga vechokwadi "Sumatriptan". Ndiwo chinodhaka wokutanga. Akanzwisisa zvinenge zvakazara uye rudzi mureza pakurapa migraine. Mumiedzo zvekuchipatara zvakatora 60 zviuru vanhu muchirongwa. Kokutanga zvinodhaka sezvayakawanikwa ne GlaxoSmithKline muna 1989.

Kumboda "sumatriptan" chaitwa muchimiro kwakajairika mapiritsi, zvemapuranga mapiritsi, uye pfapfaidzo. Mumwe nomumwe wavo anoshanda zvakafanana. The kunonyanyisa chaizvoizvo pashure kutora mapiritsi kunoitika pashure maviri uye hafu maawa, uye pfapfaidzo - maminitsi 90.

chizvarwa chechipiri

Triptans - zvinodhaka nokuda migraine, kuva boka iri - vakawanda. Mukuwedzera, havasi zvakakwana kudzidza. Kuagadzira muchimiro mahwendefa. Pakati inonyatsobudirira vari:

1. "Natriptan" - chakazoitika Zvakacherechedzwa kuti inenge awa pashure ingestion. Marwadzo ipfupi. Kunonyanyisa zvazviri kunoitika mumaawa mashomanana.
2. "Frovatripan" - mushonga uyu zvishoma simba, asi makagamuchira zvishoma pachena hachifadzi nemishonga.
3. "Zolmitriptan" - unoshanda pashure maminitsi 15 pashure kutarisira. The kunonyanyisa zvazviri kunoitwa pashure inenge awa. mushonga uyu zvakanaka chaizvo kuzorwisa yepamusoro.
4. "Rizatriptan" - rakafanana gadziriro vorudzi wokutanga, asi ane zvakawanda raidudzwa kushanda.
5. "Almotriptan" - mushonga uyu hunopfuura "Sumatriptan" kanoverengeka kunyatsoshanda. The kunonyanyisa zvazviri kunoitwa pashure pemaawa 1.5.
6. "Relpaks" - mushonga uyu zvikuru Funga zvimwe zvokugadzira panyaya matambudziko pamusoro uropi kuti ropa midziyo. Kunyange zvazvo kuita zvakafanana zvikuru "sumatriptan".

Zvinodhaka kuti migraine (triptans): mutengo uye dzave dziri mutambo

Kuti kuita zvakawanda pachena izvo zvinodhaka zvivepo, ratinoparidza tafura:

Features mutambo

Saka, sei zvakanakisisa kutora triptans kuti migraine uye nomusoro? Instructions iyi nyaya kuchabatsira kuziva uwandu husingakuvadzi uye nguva rubvumo. Chinhu chikuru - yeuka kuti kana kurwadziwa kuti kunowedzera zvishoma nezvishoma uye asina hunhu migraine, tora mishonga yakadaro chirongwa haatombotauri musoro. Muchiitiko chino, unofanira kutora asiri chaicho unonyaradza marwadzo. Izvi zvakakosha kwazvo. Kazhinji, triptans zvinofanira kutorwa pashure kuguma Aura, kana kwete paya pane maawa maviri pashure kutanga kusanzwa. Uyezve, kana munhu triptan migraine uye kunogona kushandiswa nevamwe zvinodhaka, zvakadai metoclopramide kana domperidone.

Kana pfapfaidzo, dzinofanira kushandiswa panguva zvakakwana iziviswe kuda kurutsa uye Chokwadi, kurutsa. "Imigran" rinogona kutorwa kubvisa migraine mamiriro. Triptanity anogona kupiwa kwete chete kune kukura chirwere, asiwo nguva pakati kurwisa kuti kudzivirira. Izvi anobvumirwa muzviitiko apo:

1. unhu murwere upenyu hwakaderera.
2. NSAIDs zvakaoma chaizvo kuti kurapa.
3. Migraine kurwiswa kuitika kakawanda kupfuura kaviri mumazuva 30.

Mabatirwo nemusoro

Kubvisa migraine kurwisa, zvakakodzera kutanga kuedza kutora 1,000 milligrams acetylsalicylic acid, chinonhuhwira drink rine caffeine, kana 10 milligrams zvinodhaka "Motilium". Kana pashure maminitsi 45 nomusoro kukapfuurira, zvinokwanisika kushandisa triptan.

Zvinofanira kucherechedzwa kuti mumamiriro ezvinhu apo kuti kurwisa matatu nonspecific unonyaradza marwadzo haana kupa kutsvakwa mugumisiro, unogona pakarepo kutora mushonga migraine. Kana paiva Aura, kushandiswa asipurini kunodyira chete pashure pacho akatanga, uye pashure panowanikwa kurwadziwa - zvinodhaka nokuda migraine (triptans).

Zvakadini kana kurwadziwa akadzoka?

Inenge 50% wevarwere pane kudzoswa nemusoro mumazuva mashomanana. Nyanzvi vanokurudzira kuti mumamiriro ezvinhu akadaro zvakare kutora mishonga kuti migraine - triptans. Zvinofanira kurangarirwa pamusoro vaifanira nezuva dose zvinodhaka. Kutora mushonga hapana kwokutanga pane maawa maviri pashure yokutanga piritsi. Kana nomusoro inogona akashivirira, murwere anogona kutsiviwa triptans nonspecific unonyaradza marwadzo.

Zvinokosha kucherechedza kuti kusagadzikana rinodzokera kazhinji kuchengetwa varwere pamwe zvakakwana refu tichibatwa hunogara pasina mushonga marwadzo kwemaawa anopfuura 24. Kunyange apo kutora chero triptan kakawanda zviitiko zvakadaro kuchinja. Zvisinei, nyanzvi dzinofunga kuti kushandiswa "Eletriptan" uye "naratriptan" anobatsira kuderedza nhamba kurwiswa matsva.

Kana pasina mugumisiro

Pane nguva apo zvinodhaka nokuda migraine (triptans) uye zvinodhaka non-zvakananga musapa aida mugumisiro uye asingauyi kubvisa marwadzo. Muchiitiko chino, chiremba anogona mishonga kunzwisisa kurapa, izvo unotora kutungamirira zvinodhaka anticonvulsant, uyewo B-blockers. zvinodhaka izvi zvinosanganisira "nadolol," "acebutolol", "penbutolol", "Labetanol", "Betaxolol" uye vamwe.

Side anokonzerwa triptans

mishonga izvi zvinogona kutorwa mazuva chete 10 pamwedzi. Zvikasadaro, unogona kuona zvimwe zvinetso. More kakawanda Kushandisa triptans kunogona nemusoro, kunoitika Varwere kugamuchira zvinodhaka. Uyezve, chiito mishonga yakadaro vane mamwewo matambudziko, kusanganisira:

1. A ushamwari uye kuomarara ari maoko nemakumbo, hope, kurukutika, dzungu, nehanya.
2. Myocardial dumbu kana chirwatata, ischemic colitis, Hemorrhagic manyoka, muromo yakaoma, abdominal marwadzo uye svoto.
3. Myalgia uye tsandanyama simba.
4. Coronary vasospasm, myocardial infarction, angina pectoris, tachycardia, palpitations.
5. Polyuria, uye kuita weti kakawanda.
6. Anaphylaxis, angioedema, urticaria.

Pasinei neizvi zvose, triptans nokuti migraine - mishonga akurumidze-kuita. Kana iwe zvinodhaka mukanyatsoteerera maererano nemirayiridzo, ipapo hapana dambudziko. Zvakaipira chete zvinokosha mishonga dzakadai - mutengo. Haasi wose anogona kutenga mushonga wakadaro.