"Komfoderm": mirayiridzo kushandiswa, description, akafanana, analogs uye wongororo

Chii chaunoziva pamusoro pekugadzirira akadai "Komfoderm"? Mirayiridzo yokushandisa, mutengo, ongororo, uye analogs ari mukuru zvatariswa zvinodhaka ichi anozivikanwa shoma. Saka, munyaya ino, takasarudza kupa ruzivo zvose pamusoro mishonga.

Form, akafanana uye tsananguro

Kugadzirira "Komfoderm", mirayiridzo kushandiswa inorondedzerwa gare gare, anogadzirwa muchimiro jena ruomba uye kunhuhwirira (zvive pasina uye kuva ruomba tint).

The vanoshingaira zvinoumba mumiririri uyu kukamura uchishandisa chikumbiro vari atseponat methylprednisolone uye urea. Uyewo somushonga mafuta vari ebetsero zvinhu zviri kukurukurwa sezvo mvura Paraffin, propylene glycol, polysorbate 80, carbomer interpolymer (mhando A), trometamol, metipparagidroksibenzoata uye mvura Yakanatswa.

semushonga

Chii yomunharaunda chinodhaka "Komfoderm" (ruomba)? Mirayiridzo dzokushandisa inoshuma kuti glucocorticosteroid uye keratolytic mumiririri panguva imwe chete. Chiito yayo nokuda peculiarities ari hurongwa zvaisanganisira kwaro sezvamunoita. Funga zvose zvikuru ehupfumi dzavo.

Methylprednisolone aceponate - izvi non-halogenated chakaita zvokugadzirwa steroid. Nokuti kunze kushandiswa, zviri anokwanisa kudzvanyirira sema uye anogumbura ganda siyana uyewo siyana ayo chokuita kunowedzerwa kuwanda. Kushamwaridzana kwakadaro kunotungamirira chinokosha zvinoderedza pachinangwa zviratidzo kuzvimba (erythema, edema, soka) uye kuzviitira nezvekufadza (kuvaviwa, kugumbuka, marwadzo, etc.).

Hatigoni kutaura kuti kushanda fuma iyi zvavakabvumirana dose yawo systemic migumisiro pamusoro womunhu muviri zvishoma.

Shure kwenguva refu uye akadzokorora kushandiswa methylprednisolone aceponate pamusoro guru ganda hukawanika (40-60%), uyewo nokuiswa ayo pasi occlusive dressings Varwere kwete kuchengetwa hadzina kufambiswa zvakanaka mune adrenal omumuviri, kusanganisira haana akachinjwa cortisol mumatunhu.

The fuma iri mubvunzo anokwanisa kusunga kusvika glucocorticoid intracellular receptors, zvichikonzera dzakasiyana-siyana zvipenyu migumisiro. Zvikurukuru, izvi zvinotungamirira kwemakemikari induction macrocortin usage. In ichi yokupedzisira kuchititadzisa arachidonic iine acid kusunungurwa uye paumbwe anogumbura nevamiririri vakaita leukotrienes uye prostaglandins.

Ndezvipi zviri muchinangwa pakugadzirira urea "Komfoderm"? Mirayiridzo dzokushandisa inotaura kuti chikamu ichi chine hydrating uye keratolytic nemigumisiro. It anosunga mvura, nokudaro kunyoroveswa ari stratum corneum kunoita ganda.

Kunze keratolytic chiito, urea uye Exhibits proteolytic basa.

kinetics

Ko ruomba wefodya, "Komfoderm"? Mirayiridzo dzokushandisa Inoti kuti pashure pokushandisa chishandiso methylprednisolone aceponate hydrolyzes anenge pakarepo muna dermis uye Epiderme e.

Kupfuura basa uye chikuru metabolite pamusoro fuma iri 6alfa-methyl-prednisolone 17-propionate.

The mwero dermal Absorção de Água zvinodhaka kunobva vaiona ezvinhu integument dzevanhu uye ayo nzira kushandiswa (kana pasina occlusive bhandiji).

Percutaneous Absorção de Água zvinodhaka mune vanhu vane psoriasis uye atopic dermatitis mari kuti anenge 2,5%, riri zvishoma pamusoro mwero vakazvipira utano (anenge 0.6-1.5%).

Pashure kuonana 6alfa-methylprednisolone-17-propionate mu systemic ropa vanodirana zvinonzi conjugated pamwe glucuronic asidhi nani nokukurumidza, uye ipapo inactivated.

Metabolites rinoreva zvaiona yakapedza ainyanya kuburikidza itsvo pashure pemaawa 16. The unorapa zvinodhaka havasi cumulate mu muviri. Nokuda yakaderera absorbability pakati urea nokuda kukamura uchishandisa kushanda kunoita ruomba mukana wokuti systemic migumisiro kunyora nezvavo.

umboo

Kubva ipapo vakagadza "Komfoderm" (ruomba)? Mirayiridzo yokushandisa rine zvinotevera mazita zvinoratidza:

• microbial eczema;
• sema dermatitis (kuonana);
• neurodermatitis, atopic dermatitis;
• eczema wechokwadi;
• nyore nevateereri dermatitis;
• disgidroticheskaya eczema.

Nemamwe mashoko, mushonga mu mubvunzo kunoratidzwa nokuda anogumbura dermal zvirwere, soprovozhdayuschihesya keratinization wenyonganyonga, uyewo nedzokunze mukuru aikanganiswa kurapwa pamwe kukamura uchishandisa glucocorticosteroids.

Contraindications

Drug "Komfoderm" mirayiridzo kushandiswa iyo kunodiwa kuverenga varwere vose, kwete kushandiswa:

• Hypersensitivity kuti zvinhu dzemauto;
• tiibhii kana syphilitic pezvakaitwa ari deposition pamusoro medicament;
• kutapukirwa noutachiona (kusanganisira varicella, herpes zoster);
• rosacea, perioral dermatitis mukushandisa nezvizoro
• chero kubaya;
• underage.

Medicament "Komfoderm" (mafuta): mirayiridzo kushandiswa

Price haberleri mumiririri anenge 480-530 rubles. The mushonga rinoshandisirwa zvakakanganisa ganda munzvimbo ine nhete layer kamwe pazuva.

Ya kuramba uye nezuva kurapwa pamwe ruomba ichi hazvifaniri kupfuudza kwemavhiki 12. Zvinofanira kucherechedzwa kuti kurapa ganda maronda yaifanira kuti 5 mazuva.

nemishonga

Sei pachisikirwo anogona kukonzera mishonga "Komfoderm M2"? Mirayiridzo dzokushandisa mishumo kuti vakadaro Marwadzo mashoma chaizvo. Kakawanda kuonekwa muchimiro inotevera vemo siyana: kuvaviwa, erythema, akapisa manyawi, inotungamirwa vesicular mapundu.

Pakadaro, kana medicament rinoshandiswa kwevhiki dzinopfuura mana, kana pamusoro guru nzvimbo ganda, murwere anogona kuva ganda atrophy kana telangiectasia uye kuoneka akneformnye kuchinja, tatamuka mavanga uye systemic zvinokonzerwa, izvo anokonzerwa Absorção de Água yacho corticosteroid.

Uyewo dzimwe nguva vaiona zvinodhaka kunokonzera hypertrichosis, folliculitis, depigmentation ganda, perioral dermatitis, uye neutachiona.

Consumer ongororo uye analogues "Komfoderma"

chete dzemauto "Advantan" anoreva analogs zvinodhaka ichi.

Chii vanhu vanoti pamusoro "Komfoderm" mafuta varwere? Maererano mhinduro dzavo medicament mune mubvunzo zvinobatsira chaizvo vemo nzira. Chikumbiro chacho unokubvumira kubvisa siyana ganda zvirwere, kusanganisira eczema, neurodermatitis, uye dermatitis. Mune zvimwe zviitiko, mushonga unoshandiswa kunyange psoriasis.

Zvazvakashatira "Komfoderm" mafuta zvinosanganisira kudhura kwayo, uyewo kutadza kushandisa vana.