"TSifran ST": analogues, mirayiridzo kushandiswa uye mutengo

"TSifran ST" - pamwe mushonga chete rinoita zvinhu tinidazole uye ciprofloxacin. Mwari akaronga kuti kurapwa kwezvirwere zvinotapuriranwa ari nemudumbu uye zvakavhenganiswa zvirwere, kukura iyo akabatsira aerobes uye anaerobes.

It akaita kugadzirwa dzakawanda kugadzirira "TSifran". kusunungurwa chimiro zvinodhaka - zvemapuranga pamahwendefa, ziso madonhwe, mhinduro kuti aizomupa.

Tinidazole achiumbwa pamusoro imidazole. The chigadzirwa ane antibacterial uye antiprotozoal basa, anoshandiswa zvirwere zvinokonzerwa anaerobes.

Ciprofloxacin ndowenyika mushonga, achiita zvakasiyana-siyana zvinoitwa. Kwaari muvamwe Kurovedza (dzakawanda Kurovedza, izvo giremu-akanaka, giremu negative).

Kufanana yepakutanga, uye analogues "TSifran ST", zvinobudirira kukurira mabasa.

pharmacodynamics

Tinidazole hunovhiringidza anaerobes, unoshanda mukurapa njodzi zvemapapu nhengo riri nemumuromo mhango, muna peritoneum uye pelvic.

Sezvo anaerobic Zvirwere kazhinji yakasananiswa (yakatanga nokupesvedzera Kurovedza uye anaerobic), sezvo chikamu zvinodhaka aripo ciprofloxacin mushonga, mumwe mwoyo chaizvo kwemabhakitiriya kungova aerobes.

Pharmacokinetics

Basic zvinhu wakaumbwa yepakutanga zvinodhaka uye analogues "TSifran ST", vari zvakanaka kunakidzwa nemudumbu uye kune munyama, muviri zvinwiwa. Dzavo kunonyanyisa wevasungwa aona mumuviri pashure avhareji yemaawa 1.5 mushure kupinda zvinodhaka kupinda nemudumbu.

Tinidazole ane bioavailability 100%, iri zvishoma unoratidzwa kwemaawa 10-12. Kukurukurirana pamwe mapuroteni eplasma riri kunyora nezvavo - 12%. Ekskretirovanie kunoitika muna bile, tinidazole vanenge 25% yabudiswa muna weti kuchinja. Metabolites zvinopedzwa saizvozvo. A kuduku chikamu rokuti haazotaurwizve kubva muviri ari mutsvina yadzo.

Ciprofloxacin pamwe bioavailability kweinenge 70% pazvinhu zvakanaka kunyura kana zvemukati kushandiswa. Rakapinza muruoko muviri zvokudya, chimwe chezvinonhuwira rine mu nechivako kwayo "TSifran ST" (analogue yezviri yeimwe) wefodya zvishoma nezvishoma. Ciprofloxacin anosunga kuti Plasma pa 20-40%. Mienzaniso muviri kunoitika muna chiropa, hafu dose anopinda weti anooneka kuzochinja. About 15% ciprofloxacin anotora chimiro metabolites uye vakaratidza muchimiro 15-30% of mutsvina yadzo vanobviswa, dzasara - pamwe bile. For haasaruri kubviswa anotora avhareji 4 maawa asi iyi inogona yakareba vari varwere vakwegura, uye kana murwere anotaurwa itsvo zvirwere.

Zvairatidza "TSifran ST" chinodhaka

Funga nyaya iyo rinobvumira kushandiswa mari "TSifran" mirayiridzo Chinyorwa. Price uye analogues zvinodhaka kuona kubudirira pakurapa zvinotevera zvirwere:

• zvirwere zvakasiyana, kukura iyo yakaitika pasi pokudzora utachiona (Kurovedza uye anaerobic);
• manyoka nemanyoka pamusoro etiologies siyana (amoebic vakavhengana (kwemabhakitiriya uye amoebic)).

The chinodhaka yakakodzera kurapwa zvakavhenganiswa zvirwere:

• kutapuriranwa pezvakaitwa kuitika nemumuromo mhango nhengo (.. mu t H periostitis, periodontitis);
• mubhedha maronda;
• trophic maronda, chirwere cheshuga rutsoka chirwere;
• kutapuriranwa pezvakaitwa kukanganisa zvinyoronyoro zvinyama, ganda;
• mu chisingaperi osteomyelitis;
• Zvirwere zvinokonzerwa nokushanda uye yomuka pasi chiito mabhakitiriya (aerobes, anaerobes);
• gynecological zvirwere anogumbura hunhu;
• hweHIV vari peritoneum;
• empyema;
• bapu pute;
• sinusitis, izvo akapfuura mune chirwere chimiro.

Contraindications

"TSifran" rinogona kutorwa nguva dzose. Reviews analogs kubvumira kusarudza zvakakodzera marapirwo.

Instructions unorambidza kushandisa zvinodhaka pamberi mamwe matambudziko:

• Organic CNS zvirwere;
• Leaky chenjera porphyria;
• Mwongo zvokurwara (vasingadzoreki hematopoiesis muitiro);
• zvirwere ropa (munhau).

Contraindications vari zvakare hypersensitivity kuti zvinoumba mishonga, nevana, uchiyamwisa. The mushonga hauna raitongwa varwere vaduku pane makore 18. Instructions "TSifran ST" haabvumiri kushandisa doro.

Mishonga vakwegura ane dzimwe features, saka kuva nechokwadi zvakafanira kutevera kunenge ari kupinda chiremba. Kungwarira kunodiwa kana:

• kutyorwa runoratidzwa chiropa uye itsvo;
• convulsive inoti (nhoroondo);
• pfari;
• mupfungwa kurwara;
• murombo kuparadzirwa muuropi;
• vascular atherosclerosis, iri muuropi.

Kushandisa zvinodhaka, chipimo chemushonga

"TSifran ST", imwe analoginen zvinodhaka ndivo nzira dzakasiyana siyana kushanda uye zvinoshandiswa mishonga yakasiyana. Yepakuvamba Pfungwa aiendeswa munyika kushandiswa, akatorwa pashure kudya (2 nguva zuva). "TSifran ST" kushambidzwa pasi mvura yakawanda. Zvinonzi rambidzwa vaputse kuvimbika piritsi, unofanira kuinwa yakakwana.

Zvavakabvumirana dose nokuti vakuru ndiko:

• Mahwendefa, izvo zvinosanganisira vaya ciprofloxacin uye tinidazole vaivapo 250 uye 300 MG ukuwo - 2 zvidimbu;
• mahwendefa ane ciprofloxacin uye Tinidazole 500 MG uye 600 - 1 bv.

Nokuti kukamura uchishandisa kushandiswa zvinodhaka meso anorwadza zvinoda mumwe kana vaviri samadonhwe nzira. Treatment yaifanira pamwe kwamaawa 1-4. Kana mamiriro inovandudzika, unogona kuwedzera penguva.

Side Zvazvinoita "TSifran ST" chinodhaka

"TSifran ST" (analogue wose zvinhu) anogona kumutsa vamwe kunaka siyana.

Mumatumbu System:

• gepatonekroz;
• chiropa;
• cholestatic jaundice (soro ngozi kukura kwayo varwere hosha chiropa);
• manyoka, flatulence, abdominal kurwadziwa;
• svoto uye kurutsa;
• kusingafadzi manakiro mumuromo simbi;
• murombo havi;
• kuoma kwezvinhu mucous lining muromo mhango.

Tsinga:

• thrombosis kukanganisa chepfungwa tsinga;
• kufenda;
• High ICP;
• migraine;
• dzungu, kurwadziwa nemusoro;
• pfungwa siyana;
• iratidzike seiri kubuda;
• kushaya hope;
• tremor;
• simba, nekuneta;
• nokugwinha;
• peripheral neuropathy;
• dysarthria;
• nezvinetso Kufambisa nemafambiro.

Notes nevamwe zvisingadiwi migumisiro "TSifran ST" mirayiridzo. Mutengo Pharmacies analogues kuona kwete bedzi efficacy zvinodhaka, asi kuvapo vamwe marwadzo.

pfungwa:

• madzerere;
• kuchinja mu kunhuhwidza;
• dysgeusia;
• murombo kunzwa.

Kumwoyo:

• pasi BP;
• zvachinja mutinhimira mumoyo;
• tachycardia.

Urinary maitiro :

• interstitial nephritis;
• nezvinetso excretion kuti weti;
• inotungamirwa yakawandisa weti;
• itsvo glomerular lesion;
• weti mairi ndokuumba munyu crystals;
• Blood kutsunga iri weti sezvamunoita.

Possible zviratidzo Kurwara uye nezvimwe nemigumisiro, kuchinja murabhoritari parameters, siyana kuvhiringidzika hematopoietic ino.

zvinodhaka kwavatori

"TSifran ST" (analogue yezviri zvinoriumba) haafaniri pamwe "ethionamide". The mushonga unobatanidzwa pamwe nemimwe mishonga inorwisa mabhakitiriya uye sulfonamides.

Parinoshandiswa ne "pentobarbital" akadaro kumhanyisa kuti muviri. The mushonga runogonesa kuitwa panyaya iyi uye anticoagulants.

Zvokungwarira

Panguva mushonga vanofanira kuramba pasi pokudzora chezuva sezvo shoma sezvinobvira. Zvinonzi rambidzwa kuita mabasa kuti kurapwa zvinodhaka anogona kukanganisa utano (kutarisira zvinodiwa, nokukurumidza kuratidza injini uye nepfungwa siyana). Panguva mushonga, richiona nezvezvabuda peripheral ropa.

Analogs, nhoroondo, mutengo

Kana hurukuro "TSifran ST" analogues, mutengo inokosha varwere. The anowanzodanwa kushandiswa mapiritsi. Mutengo Mahwendefa aine zviri zvinokosha zvinhu 250 uye 300 zviri MG mahwendefa vanenge 36-460 rubles mutengo apo pane 500 uye 600 MG zvikuru zvinoriumba - vanenge 79-500 rubles.

Chii chinogona kutsiva "TSifran ST"? analogs Russian vari isingadhuri. The mushonga yepakutanga inogona kutsiviwa Somuenzaniso, "Ciprofloxacin" (10-25 rubles). Indian dzomuzana, unogona sarudza "Tanidazol Ciprofloxacin +" kana "Tsiprolet A" (150-325 rubles). Zviri mishonga izvi Anonyanyowanika ne "TSifran ST".

Kutonga nezvinooneka wongororo, chepakutanga zvinodhaka kuzvigona zvakanaka zvavo chando, kunyanya kana chirwere yakatanga. Parinoshandiswa mumazuva kumwedzi mangwanani, hunobvumira kuti kurapa zhinji hadzi kuzvimba. "TSifran ST" Kurumidza aivabatsira murwere ezvinhu.

Kumboda inorwisa mabhakitiriya kushandiswa mushure akavhiyiwa uye zviitiko apo kuerera mumuviri zvikuru kuzvimba, izvo kwenguva refu nguva regai kunyangarika, sezvo pane zvakawanda kudaro nemishonga. Mutengi ongororo dzinotaura kuti analogues hainyanyoshanda uye nani zvaitombova.

Drug "TSifran ST" tora chete pashure pokuongororwa uye chiremba kugadza. Hazvina zvakafanira kuzvinzwira medicate, nokuti migumisiro yacho inogona zvakakomba.