The mushonga "Istenon": wongororo. "Instenon": mirayiridzo kushandiswa uye analogues

Chii zvingagadziriswa se "Instenon"? Mirayiridzo kushandiswa, mutengo uye zvivako zvinodhaka zvichabviswa kurondedzerwa pashure.

The sezvamunoita, chimiro, tsananguro mishonga

chambotaurwa nezvacho mushonga anotengeswa munyika ipi? Zvakadini ichi mushumo nevatengi wongororo? "Instenon" rinowanika zvinotevera siyana:

• Mahwendefa kumativi uye kupenyerera ine mvere pamusoro zvemapuranga ane chena nevamwe. Huru zvinhu zviri sezvamunoita yavo ndeinotevera: hexobendine (hexobendine ari chimiro dihydrochloride) uyewo etofillin uye etamivan. Mukuwedzera, murwiyo mishonga iyi zvinosanganisira zvimwe zvinhu: talc, magnesium stearate, pregelatinized starch, chibage starch uye lactose monohydrate.
• The zvakajeka uye Hauoneki mhinduro "Instenon" (majekiseni) aida intramuscular kana intravenous yaitonga. unorapa aro vari zvakare hexobendine (hexobendine ari muchimiro dihydrochloride), uye etofillin etamivan. Kana Excipients, ipapo kushandiswa dzavo disodium edetate, D mvura / nepfambi uye propylene glycol.

pharmacology

Mabatiro Atinofanira nzira kuita? Zvakadini zvokurapa wongororo vanoti? "Instenon" - mubatanidzwa medicament iyo kunonatsiridza muviri uye pfungwa kufamba kweropa.

Efficacy zvinodhaka nokuda ehupfumi zvainoshandiswa zvinokosha zvinhu. Ngationgororei navo zvizere.

Kuburikidza activation pakati ari reticular inotungamirwa, etamivan kukwanisa normalize kushanda Neural hunde, subcortical zvivako uye enyika cortex.

Hexobendine anovandudza uye Inowedzera kuti Utilisation kuti shuga uye O2 nokuda activation pamusoro pentose zvinogara uye anaerobic glycolysis. Izvi zvinoitika chete pasi ezvinhu okisijeni nenzara uye ischemia apo yekudyidzana vasingadzoreki oxidative phosphorylation Kurovedza. Kukuchidzira of anaerobic simba substrate oxidation rinoitwa kuti kuchinjana uye kwetunhu neurotransmitters uye synaptic hutachiwana kupora.

Hatigoni kutaura kuti hexobendine inokwanisa pakudzikamisa zvigadziriswe (vasiri) autoregulation ropa kuyerera (cardiac uye chepfungwa), izvo chokuita zvakananga simba pyruvate uye lactate (kureva zvibereko anaerobic glycolysis) ari Kanotokonya mamiriro capillaries uye arterioles ose intracranial.

Ndezvipi zviri muchinangwa kugadzirira etofillin "Instenon"? Instructions, nhoroondo akashuma kuti fuma iyi zvaanopa simba myocardial muviri uye kunowedzera cardiac goho, mamwe inowedzera kumanikidzwa (cpp) mu ischemic midziyo. Muchiitiko chino, systemic BP haachinji.

Etofillina kunobatsira musi NA sezvo kunoratidzwa nekuonekwa kweiyi ari midbrain nezvimwe subcortical zvivako, uyewo hunde nuclei uye nzvimbo (kusanganisira FSK zvenyukireya, Nhongonya autonomic mutemo vasomotor uye kufema nzvimbo yacho vagus etsinga).

Kana kushandisa mushonga "Instenon" analogs zviri pasi apa, vanenge cranial mupfungwa uye pfungwa (yakavharwa), kubviswa ischemic sitiroko segwapa chetsinga zvinetso, kuzoita hana murwere uye activation pamusoro autonomic hurongwa.

umboo

In chii mamiriro anoonekwa mushonga zvinonyatsoshanda? Zvavanotaura pamusoro inofambiswa ichi? "Instenon" yakaratidza dzokushandisa:

• post-Kurohwa mamiriro;
• zvirwere vascular kwakabva uropi, uyewo zera-ukama zvachinja murwere;
• kushomeka ropa wedzerai huru pfungwa uye zvachinokonzera;
• dzungu, vakanga kunokonzerwa zvinetso (dzichipfekeka) uropi.

Kurambidzwa kushandiswa

The medicament "Instenon" (jekiseni uye kunanzvana zvinodhaka nezvimiro vane contraindications) rambidzwa kugadza:

• convulsive zvirwere;
• mamiriro ezvinhu akasimba excitation;
• zviratidzo cheBP (intracranial), kusanganisira kwenguva refu nemusoro, kurutsa, uye ziso nenyonganiso;
• pfari;
• pfungwa ropa;
• hypersensitivity kune zvokubikisa zvinoreva.

With Tikanyatsoongorora medicament inofanira kushandiswa pashure sitiroko, uye arterial stenosis (carotid), kwamuka nokuda arteriosclerosis.

Drug "Instenon": mirayiridzo kushandiswa

Mutengo zvinodhaka riri pamusoro 350-400 rubles. Sei chinofanira kushandiswa sei? Zvichienderana kwokuomerwa uye Chirwere mumiriri muchimiro kugadzirisa chinotarisirwa intramuscularly kana nomutsinga zvishoma nezvishoma. To ichi ampoule Pfungwa rinoshandiswa 1 2 nguva pazuva.

Uyewo, kuti medicament anogona akasarudzwa kuva donhwe intravenous aizomupa. Muchiitiko chino, zviri ushandiswe 1 ampoule 2 nguva pazuva, pamwe 250 ml 5% aqueous mhinduro kubva levulose.

Kamwe uvandudze murwere anogona kupfuurira kurapa nomumukanwa chimiro zvinodhaka. Panyaya iyi, hwendefa chinobviswa nomuromo mune imwe mari 1-2 zvidimbu katatu pazuva. Kufadza daily chipimo chemushonga ari mumiririri ndiyo 5 Mahwendefa. kurapa kwakadaro rinoitwa kwevhiki nhanhatu.

chiito divi

Maererano nenyanzvi, mushonga "Instenon" Kashoma kunokonzera nenjodzi. Mune zvimwe zviitiko, kana kushandiswa pamatunhu mishonga murwere tinganetseka nemusoro, uyewo yakaderera BP uye kukudziridza akatsvuka paganda.

Overdosing uye kudyidzana

Zviratidzo ovhadhozi kuti chokushandisa ichi vari nomusoro, chiso Flushing , uye tachycardia. Kubvisa inoti ivavo zvinodhaka zvinofanira kwakaregwa, uye ipapo kutangazve kushandiswa kwayo, asi kune muduku chipimo chemushonga.

In yakafanana kushanda zvinodhaka "Instenon" uye nevanhu kuti kuderedza platelet basa (kusanganisira acetylsalicylic acid), kungawedzera antiplatelet zvazviri, nokuda simba hexobendine.

Kana kugamuchira zvinhu zvine caffeine pamatunhu mishonga anogona kuderedza kuchirapa efficacy kuti "instenon".

chaicho mashoko

Chii varwere vanofanira kuziva asati kutora mishonga iri mubvunzo? Maererano zvakabatanidzwa mirayiridzo, dzimwe nguva nokukurumidza intravenous "instenon" murwere yekudyidzana chinja BP. Panyaya iyi, kuti aizomupa nguva 1st dose hakufaniri zvishoma pane maminitsi matatu.

Panguva kurapwa pamwe mumiririri uyu murwere vanofanira kungwarira zvikuru kana kushanda michina ngozi uye kutyaira.

Similar zvinodhaka uye wongororo

"Instenon" inogona kutsiviwa pachishandiswa dzakadai se "Citoflavin", "Armadin" "Glycine", "Boluses Huato", "Keltikan", "Meksidol", "Cortexin", "Meksiprim", "Nucleo CMF Forte", "neurotrophin "" Tryptophan ". Zvinofanira kucherechedzwa kuti zvinodhaka izvi vane zvinoratidza dzavo uye features, saka vanofanira kugadza chete ane ruzivo nyanzvi.

Vanoti chii pamusoro mushonga chipo vatengi? Maererano mashoko avo, mushonga kashoma hunoita kuti pave paine matambudziko, saka riri basa kusvikira vana. kugamuchirwa ake zvikuru anovandudza chepfungwa ropa kuparadzirwa uye anobvisa mamwe matambudziko nemidziyo ropa.

The chete drawback zvinodhaka ichi anokurumidza kuchinja muviri kusvika mushonga. Panyaya iyi, tinogona kutaura noushingi kuti "Instenon" Foreign mukutsinhana ibhuku asina chinangwa kushandiswa kwenguva refu.