Kubva chii anobatsira "Hypothiazid". "Hypothiazid": richitungamirira, wongororo, analogs

Nhasi isu kwamuri kuti pane anobatsira "Hypothiazid"? Uye zvinhu ino zvichagoverwa mirayiridzo kushandiswa kwezvinodhaka, mutengi ongororo, chimiro waro yokusunungurwa, uye zvimwe zvivako.

Description rekugadzirira, chimiro, uye Zvinoumba kavha

Kubva chii anobatsira "Hypothiazid"? Tisati tapindura mubvunzo uyu, zvakakosha kuti kudini chimiro zvinodhaka ichi anoenda chemishonga.

"Hypothiazid" anogadzirwa muchimiro mahwendefa chena (angava grayish Hue). Vane raundi uye sandara chimiro, ngozi kudivi uye achiita zvokutemera "H" - kune mumwe.

The kushingaira che zvinodhaka fuma hydrochlorothiazide. Uyewo hazvina unotora ebetsero zvinhu zvakadai magnesium stearate, lactose monohydrate, talc, gelatine uye starch chibage.

In kutengeswa chivako ichi yaipiwa mu mhoni packs it, izvo mumapepa mumabhokisi makadhibhokisi.

The zvinodhaka

Chii chinodhaka "Hypothiazid"? Kubva chii anobatsira mushonga uyu?

Maererano mirayiridzo, vaiona mushonga uri diuretic. mashandiro ayo chikuru chiito chiri kuwedzera diuresis kuburikidza chinovhiringidza pakati reabsorption pakati yavaibvisa uye chloride ions munzvimbo chokutanga munzvimbo renal tubules. Izvi zvinotungamirira vawedzere excretion pamusoro kuiisa chlorine, yavaibvisa, uye, sezvo zvakaguma mvura.

Zvinofanira kucherechedzwa kuti, pashure kugamuchira akati medicament kunowedzera excretion nedzimwe electrolytes, uye zvikuru zvakananga potassium uye magnesium.

In yakakwirira kuchirapa mishonga natriuretic uye diuretic migumisiro zvinodhaka ichi ndiwo chete.

Diuresis uye natriuresis kuitika kwemaminitsi 120 uye ukasvika zvazvingava kunonyanyisa pashure 4 awa.

Zvinofanira kucherechedzwa kuti medicament kunoderedza carbonic anhydrase webasa kuwedzera excretion pamusoro bicarbonate ions. Zvisinei, zvazviri uyu zvinodhaka simba uye asingauyi kukanganisa ph yacho weti.

Active chirungiso "gipotiazid" ane antihypertensive ehupfumi. Hatigoni kutaura kuti zvingagadziriswa pasi kufunga haana kumbochinja kwomuzvarirwo BP.

The kinetics zvinodhaka

Kana mishonga wefodya "Hypothiazid"? Instructions, chigadzirwa rondedzero mushumo kuti hydrochlorothiazide haisi zvachose, asi nokukurumidza woga kubva zvomudumbu hurongwa. Izvi zvikaramba kwemaawa 6-12.

Kana muchigamuchira mushonga nomuromo ari chipimo chemushonga 100 MG yayo nenhamba wevasungwa zvasvika pashure maawa 2,5 muna plasma.

Kukurukura mapuroteni eplasma ndiyo 40%.

Maererano nenyanzvi, hydrochlorothiazide asunungurwa pamwe mukaka uye chinopinda kuburikidza placental chipingamupinyi.

Excretion of chishandiso akatakurirwa itsvo mumaawa 6.

Medicament "Hypothiazid": chii zvinobatsira?

mushonga uyu nachiremba:

• kutadzisa nokuumbwa matombo ari Urinary turakiti vanhu vafanorongerwa kuti chirwere (kuderedza hypercalciuria);
• neBP (monotherapy kana akabatana nevamwe zvinodhaka antihypertensive) ;
• nokudzora polyuria (kunyanya nephrogenic cheshuga insipidus);
• Edema chirwere siyana mavambo (premenstrual Makakatanwa chirwere, nephrotic urwere, renal kukundikana, chisingaperi hunhu, rikwanise glomerulonephritis, corticosteroid kurapwa, congestive mwoyo kutadza chirwere hunhu, portal neBP).

Contraindications

Chokwadi chii chinoita "Hypothiazid" takaudza kumusoro. Uyewo kungwarira contraindications ose chokushandisa ichi. Idzi dzinosanganisira:

• Children pasi makore matatu;
• renal kukundikana kwazvo;
• anuria;
• chiropa kukundikana kwazvo;
• Addison nehosha;
• chirwere cheshuga unmanageable;
• refractory hypokalemia, hyponatremia, hypercalcemia;
• yakawedzera aikanganiswa zvinodhaka, uye rinobva zvenyaya sulfonamides.

Nokungwarira yokunyanyisa inofanira kushandiswa ichi chishandiso ischemic mwoyo chirwere, hypokalemia, chiropa cirrhosis, hyponatremia, gout, hypercalcemia, kushanda kuti cardiac glycosides, lactose kusashivirira, uye vakwegura.

Drug "Hypothiazid": mirayiridzo kushandiswa

Reviews analogues vaiona zvinodhaka wataurwa panoperera nyaya.

Mahwendefa zvinofanira kutorwa pashure zvokudya. dose dzavo kusarudzwa mukufamba kurapwa, nomunhu.

Initial dosing zvinodhaka nokuda vakuru:

• premenstrual Makakatanwa chirwere: mishonga rinotanga kutanga zviratidzo pamberi kumwedzi (mu mari 25 MG kamwe pazuva).
• Edematous chirwere chakangomuka siyana: 25-100 MG kamwe pazuva kana kamwe mumazuva maviri. In chakakomba zviitiko mushonga waakaudzwa 200 MG.
• BP: 25-50 MG kamwe zuva. The kuchirapa mugumisiro zvinodhaka akaratidza kuti 4 mazuva.
• Nephrogenic cheshuga insipidus: 50-150 MG nezuva (mu yakakamurwa mishonga).

Kana vana, nokuti vaiona mushonga iri ushandiswe yakavakirwa uremu. The chipimo chemushonga zuva nezuva 1-2 MG / makirogiramu.

nemishonga

Zvino, unoziva, kubva chii anobatsira "Hypothiazid". Nepo kutora mushonga uyu anogona kuva zvinotevera divi siyana:

• neanorexia, muromo yakaoma, tsandanyama chinyamunhari chinorwadza, manyoka;
• tsandanyama pari, kupatira, kurukutika, cholecystitis, utera, cholestatic jaundice;
• lethargy, pfungwa nomuviri zvemwana asati, nyota, sialadenitis;
• arrhythmia, aplastic kupererwa neropa, vasculitis, thrombocytopenia, nomusoro, leukopenia;
• dzungu, hemolytic kupererwa neropa, itsvo basa zvirwere, agranulocytosis, uye vamwe.

Analogs uye wongororo pamusoro zvinodhaka "Hypothiazid"

Reviews kuti "hydrochlorothiazide" mashoko kuti inobudirira uye nokukurumidza kuita diuretic. Kugamuchira Mahwendefa kwakadaro kunotadzisa nokuumbwa matombo ari Urinary turakiti, lowers BP uye anobvisa mumatenhere siyana mavambo.

Zvazvakashatira vaiona zvinodhaka kutakura vakawanda nenjodzi.

Similar pachishandiswa zvinodhaka ichi ndiwo: "hydrochlorothiazide", "Hydrochlorothiazide-chivharo", "Dihlotiazid", "hydrochlorothiazide-Verte" uye vamwe.