Hypercholesterolemia - nayo ... Akamutswa remafuta akawandisa. rwapedyo hypercholesterolemia

vanhu mamiriyoni 200 munyika, kutanga Europe, US uye anopera Asia uye Africa, varume - 65% vakadzi - 35%. izvi zvose migumisiro vachiongorora pakutsvakurudza nzvimbo pamusoro nhamba yevanhu kutambura kubva hypercholesterolemia yose.

Chii chinonzi chirwere ichi?

Kupindura mubvunzo uyu, mabhuku ose uye vanachiremba yokubatana: hypercholesterolemia - ane ropa chimiro dzakakwirira kwazvo remafuta akawandisa yomuropa, kana, mune mamwe mazwi - a mafuta-kufanana fuma.

Remafuta akawandisa - mumwe zvinoumba muchitokisi membranes. Zvakafanira kuti maumbirwo bile acids, pasina iro hazvibviri dzose kugaya, anowana kutiisa muviri zvokudya, uye ari zvinoberekwa chiropa yedu. With Yakaumbwa bonde uye adrenal mahormone. Munyaya ino tichakurukura zvinhu zvakakwirira remafuta akawandisa uye chii vari zvinokonzera chirwere ichi.

The zvinokonzera mukuru remafuta akawandisa

Where anoita yakakwirira remafuta akawandisa? Zvikonzero anogona kuva akasiyana zvikuru. Somuenzaniso, mumwe cores ari kuwana fuma kupinda muviri pamwe mukuru-mafuta kudya. Nokuda mukuru zviri remafuta akawandisa mu mafuta zvokudya zviri rakachengetedzwa pamasvingo midziyo ropa, zvichiguma nokuumbwa plaques kuti ruchavhiringidza kufamba kweropa, nokudaro vachiwedzera pangozi yomwoyo kana sitiroko. Munguva ichangopfuura, nokuda kwezvokudya zvinovaka muviri zviitiko nechirwere pakati hypercholesterolemia. Uyezve, dyisa kuwedzera nefuma kungachinja mu mahomoni uye kutya.

Kumboda ndiwo nhaka chirwere. Muchiitiko chino, remafuta akawandisa prices yakakwirira kwazvo uye vari majini kutsunga. Rwapedyo Hypercholesterolemia - chirwere iyo anokonzerwa zviratidzo kuremara basa yeEncoding ari Kanotokonya marongerwo uye kushanda kuti apoproteidam B / E. Vanhu vanotambura heterozygous rwapedyo hypercholesterolemia fomu (1 murwere pa 350-500 vanhu) unoshanda chete nehafu B / E Kanotokonya, saka pamwero ichiwedzerwa anenge maviri nguva (kusvika 12,9 mmol / l). chaiwo zvinokonzera ngozi kutanga hypothyroidism vanoonekwa, kushandisa mishonga kwenguva refu (steroids, diuretics, etc.), uye chirwere cheshuga mellitus.

zviratidzo

The guru kunyengera ndechokuti chesamende kuratidza zviratidzo munhu asingadi kunzwa. Pasina kuchinja mararamiro, murwere angangova asina kuteerera zviratidzo. Panguva ino mune ropa zvinowedzera padanho remafuta akawandisa. Kana nguva mberi simba chaitwa, kutanga hypercholesterolemia zviratidzo vachava sezvinotevera:

• Xanthoma - munhu arambe achirema of nodules pamusoro nemarunda zvakakwana.
• Xanthelasma - kuonekwa mune subcutaneous mafuta pasi namafungiro. Izvi change gobvu yellow ruvara, izvo zvakaoma kusiyanisa nedzimwe ganda nzvimbo.
• Lipoic chinhu chakakombama corneas - remafuta akawandisa bezel (chena kana grayish-chena).

In atherosclerosis, izvo zviri kukonzerwa yakakwirira remafuta akawandisa, nhengo kukuvara zviratidzo zviri kare iziviswe uye yekudyidzana kwakawedzera.

marudzi miedzo

Hypercholesterolemia - nechiidzo, kunoratidza bedzi murabhoritari pedyo bvunzo inokosha ropa. Kune mhando mbiri nemiedzo - mupfungwa nhoroondo uye mumarabhoritari kuongorora. Ivowo, vari rakakamurwa marudzi akawanda, izvo isu vakurukure pazasi.

mupfungwa nhoroondo

1. Analysis mashoko pamusoro chirwere uye zvichemo. Zviri pamusoro apo xanthomas akawanikwa xanthelasma, lipoid arc ari cornea.
2. Analysis mashoko mupenyu. Dzinotsanangurwa mibvunzo murwere chirwere uye nehama dzake, nevanhu nevamiririri zvirwere.
3. ongororo Physical. Zvinokwanisika kucherechedza xanthoma xanthelasma. Rinogona ngazviwedzerwe arterial kumanikidzwa.

Laboratory kuongorora pamusoro remafuta akawandisa

1. Weti uye ropa. Zvinofanira kuitwa kuziva kuzvimba.
2. Nemakemikari ongororo. Zvanzi kuona siyana ropa shuga uye mapuroteni, creatinine, uric asidhi ose. Zvabuda izvi zvinopa mashoko pamusoro zvaibvira kukundwa miviri.
3. Lipidogram - nzira chikuru nechirwere. Ichiidzwa kuti remafuta akawandisa-lipid, kana sezvo dzinonzi mafuta-zvakadai zvinhu. Chii? Pane mhando mbiri lipids - kuti pave kukura atherosclerosis (proatherogenic) uye kudzivirira (lipoproteins). Kana reshiyo yavo rinowanikwa atherogenic chinhu. Kana zviri kupfuura 3, muprista mukana atherosclerosis.
4. Immunoassay. Kudzidza uku anosarudza huwandu antibodies muropa. Izvi mapuroteni chaizvo kuti anobudiswa neZvapupu mumuviri uye anokwanisa kuparadza dzimwe zvinhu.
5. Genetic. Zvinonzi kuitwa kuti vasabatwa majini vari vatakuri enhaka mashoko, izvo basa kukura hutachiwana hypercholesterolemia.

Zvirwere dzinoitwa hypercholesterolemia

Zviratidzo chirwere ichi varege kukanganisa upenyu hwomunhu, uye kwenguva yakareba kuramba asingaoneki. Zvisinei, zvishoma nezvishoma ndichifumira remafuta akawandisa kunokonzera zvakakomba. It kunowedzera ngozi dzakawanda nezvirwere zvakakomba uye matambudziko. Idzi dzinosanganisira: atherosclerosis repasi wamativi, matombo omunduru, sitiroko, aneurysm, ndangariro zvirwere, ischemic mwoyo chirwere, myocardial infarction, sitiroko. High remafuta akawandisa yekudyidzana zvinoomesa kurapa neBP uye chirwere cheshuga mellitus. All zvirwere izvi ndizvo zvinokonzera huru mukuru mwero wokufa kwevanhu munyika. Zvokurapa zvakakomba hanya kuwana nzira zvinobudirira kudzikisa remafuta akawandisa pamwero muropa somumwe nzvimbo zvinogona kubatsira kuderedza mwero wokufa kwevanhu.

migumisiro

chiremba Chero vachakuudza kuti kana pane ropa remafuta akawandisa yakawedzera, nemigumisiro mune ramangwana kutungamirira kuti siyana yematambudziko. It vaiona chikuru atherosclerosis (chirwere) - namira tsinga masvingo uye aienda pamusoro lumen, izvo zvinogona kuita kuti nokuvhiringidzirwa ropa rive. Zvichienderana sei akaronga pangagara ane atherosclerotic Dombo, voga siyana chirwere:

1. Kutsemuka atherosclerosis - inotungamirira refu BP, uye vatsigiri paumbwe chemwoyo: aienda uye insufficiency (kutadza kudzivisa kweropa) ari kutsemuka vharuvhu.
2. Atherosclerotic mwoyo chirwere (coronary tsinga chirwere) inotungamirira kuvapo kwezvirwere zvakadai:

• myocardial infarction (rufu mwoyo tsandanyama nokuda kumira ropa riyerere kwairi);
• mugari kurova kwehana;
• mwoyo zvikanganiso (STRUCTURAL mwoyo zvirwere);
• cardiac insufficiency (murombo ropa wedzerai mapazi ari yokuzorora chinzvimbo uye mutoro, izvo kunowanzoguma ropa stasis);
• atherosclerosis muuropi - kunokanganisa kurinda, uye kana zvakazara rakavhara mudziyo kunotungamirira sitiroko (chepfungwa mugove rufu);
• Atherosclerosis of arteries iri itsvo, nemhaka neBP;
• Atherosclerosis of arteries zvinogona kukonzera intestinal bowel infarction;
• atherosclerosis repasi wamativi zvichiguma inoratidza claudication.

yematambudziko

Atherosclerosis ane mhando mbiri yematambudziko: chirwere uye chakasimba. Somugumisiro, wokutanga atherosclerotic Dombo kunotungamirira kuti aienda pamusoro mudziyo lumen. Sezvo plaques vari kuumbwa asi zvishoma nezvishoma, inova chirwere ischemia umo zvinovaka muviri uye okisijeni vanopiwa mu kukwana akawanda. Chenjera matambudziko - ndiyo nechitarisiko thrombi (ropa clots), embolism (clots ropa kuti ndavhuna kubva panzvimbo mavambo, ari akatamisira ropa mudziyo spasm). Zviri zvikuru yakapinza nokuvhara lumen rwengarava ropa, icho pamwe vascular insufficiency (rikwanise ischemia), zvoita kuti mwoyo kurwiswa siyana dzomuviri.

mabatiro

Kana chirwere, "hypercholesterolemia" - kwete kutanga kurapwa pakutanga ine yakaoma kudya. It iri rakazara kuramba kushandiswa zvinhu rurefu vachikwanisa mafuta uye remafuta akawandisa (ruomba, ruomba, zai yolks, nyama mondo, chiropa) uye kuwedzera uwandu makabhohaidhiretsi, kunyanya faibha. The nyama inogona kudyiwa chete yakabikwa, zvinofanira kuverengerwa mukati zvokudya zvibereko zvizhinji uye miriwo, pasi mafuta nomukaka zvigadzirwa, hove uye hove. Pamwe chete kudya kwatemwa pamwe muviri, izvo zvichaita kuti kuderedza pakufurira remafuta akawandisa kupinda muviri. Unogona kuita chero mutambo (basketball, kushambira, kuchovha, Skiing). Hazviiti kuvhiringidza kuzvinyoresa kuti yokurovedza muviri uri kugwinya kana maekisesaizi. Kana zvakanaka sangana kudya uye muviri, zvinokwanisika kuti kuderedza remafuta akawandisa mwero kusvika 10%, izvo zvaizoitawo yekuzvidzivirira zvemwoyo chirwere ne 2%.

Uyewo, chiremba anogona mishonga gadziriro anokosha mishonga iyo vanonzi statins. Vari akanyorerwa kuderedza ropa remafuta akawandisa nekuti vane dzakakwirira kunyatsoshanda uye zvinogona kushandiswa kwenguva refu kurapwa (chepakarepo hapana nemishonga). In tsika, kushandiswa zvinotevera statins "Rosuvastatin", "Simvastin", "Lovastatin", yavaibvisa fluvastatin, "atorvastatin karusiyamu". Kana ukapa munhu mukuru tsanangudzo statins, tinogona kutaura kuti ivo yekuzvidzivirira sitiroko, reinfarction. Munguva kushandisa zvinodhaka izvi nemiedzo nokukanganisika ropa yaifanira. Izvi zvinoitwa kuti nechokwadi kuti kana normalization kuna remafuta akawandisa chemabhazi kutora kwavari. Unofanira kuziva kuti mukuru remafuta akawandisa ane chirwere - apo kuzvinzwira medicate pamwe statins iri zvachose wairambidza. Anoita yawapiwa zvinodhaka izvi, nguva uye dose nachiremba chete.

dziviriro

Kudzivirira kusvikira hypercholesterolemia iri izwi rinoreva akaita nezviito izvo unogona kuchinja zvinhu zvinokonzera njodzi - uremu kuzvidzora, yakaoma kudya muchifumiswa pamwe nokusanzwira mavhitamini, kumira doro, fodya fodya, iyo inosvitsa zvinoderedza nengozi coronary zvirwere kakawanda, vanoshingaira muviri, Zvakanyanya Kunaka Panguva Yepamuviri kuita shuga, BP. Nokuti vanhu vanotova kwakakwidziridzwa ropa remafuta akawandisa, prophylaxis rinoitwa tichibatsirwa mishonga. Chero dziviriro asi hapana kurwadzisa muviri zvine mwero uye akadzikama pakunamata.