Aspartate aminotransferase yakawedzera, zvinorevei, zvikonzero

muviri wedu, zvichida, anogona kunzi kwazvo "michina yemhando yepamusoro", izvo akasika Mother Nature. Mariri, muviri mumwe nomumwe akasiyana mu "Chimiro" ayo nezvaanogona, haasi sezvo zvisingashamisi sezvazvakaita mikuru. Uye kana iwe yakawanda yokunyatsoongorora pakudzidza yose muviri, zvinokwanisika kusangana vakawanda mashoko akaoma kunzwisisa. Kazhinji, miedzo vezvokurapa unogona kuwana mashoko okuti unpronounceable akadai aspartate aminotransferase kwakawedzera. Zvichakadai, rinoreva kuti amino iine acid cleavage musoro. Zvakakodzera tinyatsoziva ichi izwi zvishoma pedyo.

Imhandoi izwi?

Under vakapiwa shoko iri raireva enzayemu iyo paChikoro cleavage oparesheni, chero amino asidhi mumuviri. Neb akadana SGOT kana AST kunoratidzwa nemabhii makuru. The enzayemu iri munyama nhengo zhinji, dzakadai:

• chiropa;
• mwoyo;
• tsinga tishu;
• itsvo;
• mhasuro;
• rwatata;
• chirwatata;
• chiedza;
• uropi.

Uyezve, vakawanda enzayemu munyama nomwoyo, itsvo, masero etsinga, chiropa.

Saka, chirwere chipi chirwere chokuita nemiviri izvi zvinoreva kuti aspartate aminotransferase akawedzera. Mumapapu, chirwatata uye rwatata enzayemu huwandu haisi yakakura. Chine mukono muviri rakasiyana munhukadzi kumusoro basa CHIMWE CHINHU.

Functionality AST

The enzayemu iri puroteni Morekuru riri rakapa cellular zvinyama kuti nhengo dzomukati. mamiriro ayo rakavambwa nemasayendisiti Russian ari 70s. Zvaiitwa enzayemu ndiko mhanyisa nokukanganisika chinja ari mumasero. With kutora chikamu vhitamini B6, zvinokwanisika kupanana amino acids. Mugore kunzwisisa kuchinja amino acids zhinji, kusanganisira aspartic, paumbwe remubatanidzwa itsva. Yakanga nekuvongwa iye kuti kwetunhu shuga, riri saka zvakakodzera kuti muviri yedu.

Features AST

Mumwe nomumwe wedu pakupedzisira atarisana mashoko akadai aspartate aminotransferase zvawanzwa. Izvozvo zvinorevei, anoziva haasi munhu wose. Panyaya iyi, isu pachena keteni. Mune imwe nhengo utano iri enzayemu huri masero akati nhengo dzomukati, kuri iko mararamiro. chiduku chikamu AST chete anogona kupinda munzvimbo ropa. Information - wevasungwa of enzayemu mumwoyo kupfuura uwandu ropa riyerere zviuru 10 nguva.

Asi kana zvinyama ane nhengo wakaremara, ari aspartate aminotransferase, muchisunungura, mukati ropa uye chitsama enzayemu inotanga kuwedzera. The kukura zvazvingava kunoenderana mwero kukuvara tishu. Somuenzaniso, mune nechirwere pamusoro myocardial infarction, AST wevasungwa anosvika yepamusoro pashure zuva.

Mune zvimwe zviitiko, enzayemu pamwero anogona kusapfuudza mwero 5 nguva, uye chakarurama kwakadaro kunogona kuchengetwa kwamazuva 7. Zvino mumwe munhu ungashamisika kana aspartate aminotransferase (AST) yakawedzera, zvinorevei? Uyu mukuru basa iri kuzivikanwa zvikuru ezvinhu omurwere, izvo kazhinji kunoguma zvisingafadzi. mugumisiro.

Kana kuwedzera enzayemu kuwanda kunoitika zvishoma nezvishoma uye kuwedzera zvazvingava, zvinoreva kuti infarct wongoramba anowedzera. aspartate aminotransferase basa kungakonzera munhu kufa kubva chiropa tishu.

Chii chinogona kukanganisa yakakwirira basa AST?

Kazhinji, yakakwirira Kuwanda AST muropa murukova hunoikonzera myocardial infarction. Kana mari iyi enzayemu zvingava anopfuura 10 nguva ndozvakajairwa, uye akakwirira zviri, chikuru nzvimbo cardiac tsandanyama maronda. Pazuva rechina kurapwa inowanzopiwa reanalysis. zvabuda ake zvinoratidza, aspartate aminotransferase yakawedzera kana kwete. Kana zvinobudirira kurapa vanofanira kutapudza ayo yevasungwa.

High pamwero AST anogona kuonekwa maronda chiropa nokuda zvinoverengeka:

• Oncological zvirwere.
• Alcohol chepfu.
• Kufutisa.
• Kuvapo HCV.

Chete muchiitiko ichi, kuti kuongororwa zvakarurama, zvinokosha kuita mamwe miedzo. Zvisinei, yakakwirira kwevari enzayemu zvive vanhu zvimwe hwakanaka. Somuenzaniso, basa angava:

• Vana pamberi chokutsva.
• In vakadzi panguva trimester akazvitakura rokutanga.
• Kana kunyanyisa kushandisa doro.
• Kana kutora zvimwe zvinodhaka: valerian, akasiyana nemishonga inorwisa mabhakitiriya kana paracetamol.

Great muviri, zvakare, mune ichi kuremekedza inokanganisa. Uyezve, kana aspartate rwuchiwanzwa, zvikonzero vangave inovandira panzvimbo kushandisa gadziriro kwakavakirwa barbituric iine acid yaunodya kuti nhumbu kungakonzera kuwedzera AST.

Zvikonzero kuwedzera AST

Zvinokonzera zvakawedzera kwevari enzayemu, sezvo kare ambotaurwa, ingava myocardial infarction. With chirwere ichi muna 95-98% wevarwere zvose vakanyorwa mukuru webasa aspartate aminotransferase. The ukoshi inogona vezvikwata kusvika 3,000 chakarurama. / L. Mune zvimwe zviitiko, yakakwirira kwevari enzayemu kuchengetwa chiropa necrosis. Maperembudzi, akavapindurawo, anogona kukonzerwa zvakasiyana siyana nehepatitis. Padanho AST munyika iyi akapfuudza kwomuzvarirwo tsika 10-100 nguva.

Zvimwewo zvirwere kucherechedza angina, rikwanise pfungwa nomuviri zvemwana asati, mhingaidzo pamusoro bile ducts, masero kenza kana chiropa metastases. Mumwe enzayemu wevasungwa anogona ngazviwedzerwe nokuda kukuvara, mumwe nokupisa kwacho kutanga kufa tsandanyama masero vakafumura kuti vakuchidzire kuvhunduka. Izvi zvinogona kusanganisira murwere ari postoperative munguva.

Chii aspartate aminotransferase yakawedzera mwana, izvozvo zvingaratidza pamberi chiropa, chirwere chinonzi muscular dystrophy, rikwanise myocarditis, jaundice.

Zvikonzero richikwidibira AST

enzayemu yomuropa varege chete kuwedzera asiwo kudukupiswa. Izvi zvinoitika nezvikonzero zvakasiyana. Kazhinji, richiwanika vakadzi vane pamuviri. Mune zvimwe zviitiko vana uye vakuru nokuda chinonzi dystrophy, kukuvara kunosiyana zvakaoma kwazvo, chepfungwa infarction, hypothyroidism kana rikwanise pfungwa nomuviri zvemwana asati akaona kuderedzwa chechetere aspartataminotraferazy. Nokuda kusava vhitamini B6 kana atsamwira chiropa kuripowo chirwere kushayikwa puroteni Morekuru.

Zvairatidza kuti ongororo chinangwa

The kuongorora kuona padanho enzayemu AST yaifanira kuti ticherechedze kuvapo vamwe pathologies zvakakomba:

• kuitika kana kenza pezvakaitwa ari chiropa masero;
• kana pane metastases;
• aspartate aminotransferase ropa yakawedzera zvingaratidza kuvapo zvinotapuriranwa mononucleosis kana chaikonzerwa noutachiona ari nhengo dzinobudisa hurongwa;
• mhando autoimmune chirwere (semuenzaniso, DMD-Becker) ;
• myocardial infarction;
• cirrhosis;
• Ongororo kuratidza kuvapo chero siyana chiropa, kusanganisira chiropa necrosis.

Mukuwedzera, abnormality kuti tsandanyama uye chiropa, sezvo kushoma, kuita vanhu vafunge pamusoro chokuendesa ongororo.

zvakazoitika chete anogona kusimbisa kana ndeyenhema zviratidzo. Izvi zvichaita kuti kutora matanho akakodzera nguva. Kana kuchinja zvikuru zvaitika, ndiko chete nani.

Kugadzirira - rinokosha ezvinhu

Sezvo ndima vamwe bvunzo kupfuura kuongorora anofanira kubatwa chakakomba sezvo mishonga, kana kugadzwa mishonga yachiremba kana mishonga decoction, vanogona kukanganisa migumisiro kuongorora kuti kururama.

Saka, kuziva chaizvoizvo, aspartate aminotransferase hwakawedzera kana kwete, unofanira kurega kutora mishonga. Kana chipi chikonzero ichi zvisingaiti, chinofanira udza chiremba anoda kupa mashoko ose pamusoro zvinodhaka. Zvinoti, chipimo chemushonga uye nenguva yacho sevanakomana. Vakadzi rabhoritari kunovhenekwa kunogona kukanganisa pamuviri.

Analysis uye waivako mitemo

Material yokutsvakurudza ndiro chete venous ropa kana serum. zvakabudiswa Its rinoitwa usina chawadya mangwanani. Yose hakurapi kutora nguva yakawanda uye zvinoitika pasina kurwadziwa. Mugumisiro zvagadzirirwa pashure pemaawa 6-10. The serum inogona kuchengetwa kwemaawa 48 panguva imwe tembiricha kuti 15-25 inegumi. In ezvinhu unotonhorera (2-8 ° C) izvozvo zvikaramba anenge 6 mazuva.

Kana mubvunzo, apo zvinokwanisika zvakaitika kuongorora zvakadaro, zvinokosha kushandisa kuti kushandiswa mumarabhoritari kuti aite nokukanganisika Analyses. Mune zvimwe zviitiko, kudzidza AST (aspartate aminotransferase) yakawedzera kana kuipa, unogona kuenda kudzidza pakiriniki panguva yaaigara kana mishonga ipi mamiriro sangano. Chete iwe unofanira kutanga kuwana kana wake yezvirwere anodiwa michina uye midziyo nokuda kuongorora.

Normal nhanho imwe neimwe boka revanhu vane zvavo. Somuenzaniso, wevasungwa kuti AST ari achangoberekwa 25-75 U / L, apo vana zvishoma vakura (makore 1-18), ndiko 15-60 U / L. Normal nhanho vakadzi siyana 10 kusvika 36-U / L, uye vanhurume - kubva 14 kusvika 20 U / L.