Zviratidzo uye Mabatirwo hepatitis C utachiona genotypes ose nehepatitis C. HCV Medicines

Kutozosvikira munguva ichangopfuura kuti hepatitis C utachiona kwainzi chete utachiona Hepacivirus mhando. Asi wakatendeuka kubva kuti mabhiza, imbwa, nemakonzo uye zviremwaremwa vari kubatwa nechirwere ichi. Edza kunzwisisa sei nengozi hepatitis C munhu akafanana naye kuziva uye kurapa, sezvo nenguva zvokuongorora chirwere nyore zvikuru kurapa. Uyezve, chirwere kubatwa vana vaduku, uye kwokutanga riri kuona, chikuru mikana yakanaka mugumisiro.

Chii hepatitis C utachiwana

Kana munhu kuziva chirwere ichi, pakarepo rwunotanga anotambudza mibvunzo yakawanda pamusoro Hepatitis C: Chii chiri (Photo uchapupu chirwere), kushandisa upi chiremba rubatsiro, uye zvichingodaro. Jaundice kana nehepatitis utachiwana ane PARTICIPLE zvinosanganisira magene zvinhu (RNA) ari chinoumba, takapoteredzwa icosahedral mapuroteni goko uye anodzivirira encased mune lipid (kana mafuta) hamvuropu sero-hwokurara.

Hepatitis C nderimwe nemavhairasi anoverengeka anokonzera kwazvo kuzvimba chiropa diffuse. 85% yevanhu vane aiva rikwanise chimiro chirwere, muri chirwere utachiona navamwe hwake. Chirwere kunyanya kunoitika Via ropa (intravenous jekiseni vasiri chena tsono, anokwenya, ronda). Mukana wokutapukirwa kuburikidza pabonde kuonana utachiona ichi anonzi pasi, asi achine nzvimbo.

Zvinokonzera Hepatitis B mu Adults

Hepatitis C - chirwere yakakonzerwa utachiona kuti hwacho chiropa. Chiropa basa mabasa anosanganisira kubviswa kunokuvadza makemikoro kubva mumuviri, kuvandudza kugaya, kurapwa mavhitaminzi uye zvinovaka muviri zvokudya, uyewo kwemasayendisiti ropa clots panguva maronda uye maronda. Hepatitis C muna vakadzi ngozi chaizvo nokuti vacheche nokuti mwana anogona utachiona kubva mai kurwara pakusununguka. Ndokusaka zvichikosha kuti kutarisira utano hwake kana kuronga pamuviri.

jaundice hutachiwana vakura kunogona akaparadzirwa zvinotevera nyaya:

1. Kana uchishandisa non-chena jekiseni intravenous kana intramuscular zvirwere (kusanganisira zvinodhaka).
2. Nyora, kuboora muviri, jekiseni vakabata non-chena tsono maitirwe ezvinhu.
3. Munguva usina kuzvidzivirira pabonde nomunhu ane chirwere nemumwe, kana panguva ino hapana kuonana kuburikidza neropa (maronda, unocheka, maronda pamusoro sikarudzi kana panguva yekutevera). Nzira iyi inorondedzera kuti kujairika migwagwa dzokuteerera.
4. Kana ropa nzira.
5. Panguva kurapwa panguva mazino yekuongororwa.

Sneezing, vangakosora, vachidya kudya, kuchinjana Forogo, Banga Nechipunu kana zvimwe chero tactile kuonana chiropa haisi inoparadzirwa.

The zvinokonzera nehepatitis muvana

Zviratidzo uye Mabatirwo hepatitis C muna vana siyanei hosha zviratidzo nedzevakuru. Child chiropa kunosvika nenzira mbiri: kubva mai mwana (hunyambiri nzira chirwere) uye zvakananga kuonana neropa ane chirwere munhu (the parenteral nzira chirwere). Utachiona hunogona kutapukira kubva amai utachiona kuti achangoberekwa pakusununguka, kakawanda nyaya dzakadaro anenge 4-5%. Kana zvinhu zvakadaro kuchimuka, mukadzi aida kuita caesarean chikamu, izvo zvishoma zvinoderedza ngozi kupararira nehepatitis B utachiona achangozvarwa. Chirwere vana nzira yechipiri kazhinji unowanikwa siyana dzokurapa kupindira, mazino kurapwa, kwokubatsira zvinodhaka Via chena zviridzwa, hemodialysis, ropa uye dzimwe nzira dzokurapa.

In kuyaruka, sapamazuva vakuru, izvozvo anowedzera mikana kuwana nehepatitis kushandiswa kwezvinodhaka. Uyezve, mukana wokutapukirwa muvana kuyaruka akawedzera kutyora mitemo utsanana ganda nyora, kuboora muviri uye zvimwe zvinhu. Kana kuveura ndebvu talk zvigadzirwa zvoutsanana kuburikidza mavanga abrasions paganda kupinda muviri kunogonawo pinda wanda.

Zviratidzo nehepatitis B nedzevakuru

Kazhinji vanhu vakawanda vane hepatitis C havana zviratidzo yo chirwere. Chirwere chirwere hariwanikwi kusvikira kusvikira chiropa hauna kuumbwa scarring (cirrhosis). In chirwere ichi kazhinji achiperekedzwa Kazhinji simba, kunyanya kuneta uye ane nonspecific zviratidzo kunyange tisina cirrhosis.

Zviratidzo kazhinji akaratidza zvikuru akazotevera noutachiona chiropa incubation nguva kubva 15 kusvika 150 mazuva. Utachiona vanhu pasina zviratidzo chirwere chinotyisidzira vamwe, sezvo anoita somunhu mutakuri utachiona uye zvinogona kutapurira vamwe kupfuura nzira. The chikuru Zviratidzo chirwere zvinosanganisira zvinotevera:

- kurasikirwa havi;

- zvakawanda zvive, utera;

- kuda kurutsa, kurutsa;

- manyoka;

- kungoerekana kunoshamisa uremu pasina chikonzero;

- yellowing ganda, sclera eyeballs (anonzi saka chirwere dzakakurumbira jaundice);

- Kuchinjwa weti ruvara (kune shava) uye chetsoka (faeces whitish).

Zviratidzo nehepatitis muvana

Paavhareji incubation nguva kuti nehepatitis mwana anogona kugara kubvira pamazuva 15 kusvika 6 mwedzi. Zviratidzo jaundice muvana kuitika asingasviki 50% nyaya uye akaratidza zvikurukuru nokuda yellowing ganda nevachena kwemaziso. Kazhinji Icteric kumwedzi kunotora kusvika 3 mavhiki. Nekuti nehepatitis hwokuratidza kuzvimba chiropa, mwana zvachose kudhaka kunoitika, izvo achiperekedzwa kuda kurutsa, kurutsa, manyoka. The chenjera chimiro chirwere kunotanga zvishoma nezvishoma, zviratidzo kuwedzera zvishoma nezvishoma, apo pane pave dyspeptic zvirwere uye astenovegetativnogo syndrome. Zviratidzo jaundice muvana angaperekedzwa fivha, nomusoro. Rakabuda ruvara mutsvina yadzo, weti, nekusiyana, inova shava ruvara.

Vanozivikanwa Zviratidzo uye Mabatirwo hepatitis C zvine chokuita, sezvo kunonoka zvokuongorora kana kusavapo kurapwa muna 10-20% vose nyaya rikwanise chimiro jaundice chirwere anova chisingaperi. Chirwere jaundice Kazhinji asymptomatic uye kazhinji dzakaonekwa munguva kurongwa vaongo- mwana kana nguva yave akarasika uye hosha ichiri naye upenyu. vana ava vane wakawedzera kuneta, asthenia, extrahepatic zviratidzo (telangiectasia, kapillyarity).

Diagnostics

Nokuti kuti rikwanise HCV utachiona rinowanzova asymptomatic, zvinokosha chaizvo mangwanani chirwere chirwere chacho. Kana achipfuura chisingaperi mikana chirwere vasabatwa akaderedza chirwere kuramba undiagnosed uye anogona kuva zvakakura yematambudziko zvakadai cirrhosis kana kenza chiropa.

Kuonekwa utachiona mumuviri kunoitika kuburikidza Pakusarudza kwevari antibodies muropa, uye ipapo kwakaitika okuwedzera miedzo kuziva nemavhairasi RNA. Huwandu RNA muropa (nemavhairasi mutoro chakarurama) haina correlated nehosha zvakaoma kwazvo, asi zvinogona kushandiswa kuongorora zvakaitwa nhengo aibatwa. Chiropa biopsy inoshandiswa kuongorora kukura kwayo kukundwa chirwere (nhengo zvakakanganisika scarring masero), kukosha iyo zvinokosha kuronga mishonga.

Chirwere rinoitwa muna 2 mumatanho:

- Kuongorora kuti antibodies kuti utachiona jaundice anogona kuona kana munhu utachiwana;

- uine muedzo antibodies rinoitwa neboka nucleic iine acid munhu akaidza nokuda HCV RNA, kuona chimiro chirwere (chakasimba kana refu).

Zvadaro, nemiedzo dzakanaka, chiremba anofanira kuongorora ukuru kukuvadzwa chiropa (fibrosis kana cirrhosis). Izvi zvinogona kuitwa biopsy kana siyana vasiri invasive bvunzo. Uyezve, murwere ucharwira murabhoritari bvunzo yokuziva genotype pamusoro tisawirirane pakati nehepatitis C. Mwero kukuvara chiropa uye genotype zvinoshandiswa zvisarudzo pamusoro kurapwa kurapa chirwere uye.

The genotypes pamusoro hepatitis C

Kuti kurapa chirwere kuti vabudirire, zvakakosha kutsanangura zvinhu genotype utachiona. Genotypes HCV rakakamurwa siyana kwemarudzi matanhatu. Kazhinji, varwere utachiwana pamwe genotype imwe chete, asi mumwe nomumwe wavo zvamazvirokwazvo musanganiswa kufanana nemavhairasi inonzi quasi-mhuka. Vane tsika mutate uye kuva nemishonga mamiriro kurapa. Zvanzi rinotsanangura kuomerwa pakurapa chirwere jaundice.

Pasi mazita akasiyana genotypes echirwere hepatitis C:

1. Genotype 1a.
2. Genotype 1b.
3. Genotype 2a, 2b, 2c, 2D.
4. Genotype 3a, 3b, 3C, 3d, 3e, 3f.
5. Genotype 4a, 4b, 4c, 4D, 4e, 4f, 4g, 4h, 4Ndakauyisa, 4j.
6. Genotype 5a.
7. Genotype 6a.

The genotypes pamusoro HCV zvinokosha vanachiremba kana achibudisa kuchirapa audzwa. Somuenzaniso, genotype 1 ndiyo yakaoma zvikuru kurapa, uye varwere HCV genotype 2 uye 3 ikarumbidzwa nani kurapwa pamwe mubatanidzwa yeAlpha-interferon pamwe ribavirin. Uyezve, kana mishonga inonwiwa, zvavakabvumirana nguva kurapa kunobva genotype.

Mabatirwo Hepatitis C

Zviratidzo uye Mabatirwo hepatitis C zvine chokuita, nokuti kurapa kunobva kusanganisira pamusoro zviratidzo chirwere. Asati kurapwa kunofanira kuitwa kwazvo kuongororwa kuti uone nzira yakanaka nzira murwere uye chirwere chake. Mukuwedzera, pahwaro chirwere mashoko chiremba anogona kusarudza chii Hepatitis C ndiro inonyatsobudirira nomumwe nyaya imwe neimwe. Modern mwero mabatiro kuti jaundice kunosanganisira antiviral kurapa ne "interferon" uye "Ribavirin", izvo zvinobatsira pamusoro genotypes zvose. Zvinosuruvarisa "Interferon" haasi zvikuru inoshandiswa mukurapa, ine mugumisiro wakaipa pamusoro mamiriro vakawanda varwere, uye kutaura zvazviri musanganiswa wemishonga ribavirin pamwe kwezvinodhaka uyu, zvichida, mushonga kuti hepatitis C zvevakomana.

Kufambira mberi Scientific zvakakonzera pokumuka zvinodhaka antiviral itsva kubva jaundice, zviri hubudirire, nani uye zvikuru zvinotonzi pane munazvo. It antivirals zvakananga nokuita (PDP), izvo anokwanisa kwete chete husava pakurapa chirwere, asi kuwedzera chikamu dzevarwere vyzdoravlivaemosti. Zvisinei, mishonga antiviral vane zvakakomba nemishonga uye kazhinji kukonzera zvirwere izvi Varwere:

- nomusoro;

- dzihwa-zvakadai zviratidzo;

- svoto;

- nekuneta;

- muviri pari;

- kuora mwoyo;

- ganda rashes, neutachiona.

Kana mwana nechirwere hepatitis C, kurapwa zvinofanira zvainanga mukudzivirira yezwi iri rikwanise chimiro chirwere kuva chirwere. Zvipatara uyewo kumboda yakaoma uye rinosanganisira anofambidzana akadai interferon kugadzirirwa recombinant, reaferon mu parenteral muchimiro viferona uye rectal suppositories. Treatment regimens vanosarudzwa mumwe nomumwe mwana mumwe.

Nekuti vana makore 7 uye kuyaruka vanogona basa mubatanidzwa zvinodhaka, "interferon" uye "Ribavirin". Uyewo ngaagadze inductors ( "TSikloferon") uye immunomodulators ( "Taktivin"). Duration kurapwa kuti jaundice muvana anoenderana zvinhu zvakawanda, kubvira 24 kusvika vhiki 48. Kana nechirwere hepatitis C, kurapwa kunofanira achiperekedzwa zvokudya, tichiramba muviri uye mararamiro, kusvuta kumbomira uye doro. Zvinokosha kuona mubhedha zororo uye kudzivisa kushandisa zvinodhaka zvisina kufanira.

Kune nzira dzekare kuti Mabatirwo jaundice, asi kushandisa kwavari, iva nechokwadi kuti bvunza chiremba wako, kuti arege kukuvadza muviri uye kwete kutowedzera chirwere.

Maberere nemigumisiro

Kana varwere kuzviona hepatitis C, sei iwe unogona kurarama nayo, zvichida mumwe wemibvunzo inokosha yavanofanira bvunza chiremba. Pakarepo zvinofanira kucherechedzwa kuti Zvaifungidzirwa achaenderana nenguva vasabatwa zvirwere uye kubudirira waakaudzwa mishonga. Time akaratidza zviratidzo uye Mabatirwo hepatitis C, kuwana kodzero - abudirire. Zvipatara rakanakira mukuru ezvinhu omurwere, rinopa zvakanaka kuitika uye anowedzera mikana yakanaka mugumisiro. Maererano nenhamba, vanenge 20% wevarwere avo vakabatwa chiropa, anyatsopora, kunyange zvazvo izvi hazvirevi kuti vari kudzivirirwa ramangwana chirwere. The yasara 80% wevarwere kuva chisingaperi chirwere (pakuonekwa mamirire zviratidzo kana asymptomatic). vanhu ava vanoramba rwarisa vamwe kuti upenyu, sezvo vari vatakuri utachiwana.

Kana chiremba rinozivisa murwere Hepatitis C (zviratidzo), kurapwa uye nemigumisiro maperembudzi - mashoko anofanira akakurukura murwere nekukurumidza uye nenzira pindika muchimiro. Kana munhu kurarama hepatitis C kuti kwemakore, iye kazhinji kuva zvinotevera matambudziko:

- chisingaperi chiropa;

- cirrhosis;

- kenza chiropa.

dziviriro chirwere

Sezvineiwo, pari zvino hakuna mushonga pamusoro jaundice. Varwere vakambova hepatitis C, siya nezvevakuru chii nani kudzivirira chirwere pane kurapa nayo. Saka, kudzivisa kupararira kwezvirwere uye zvimwe zvirwere ropa nezvipembenene, vanhu vanofanira kuchengeta zvinotevera zvinodiwa:

1. Dzivisa kugoverana pachedu zvinhu kupfeka uye kushandisa zvinhu kuti zvionekwe kwakasvibiswa ropa (semuenzaniso, reza, toothbrushes, etc.).
2. Dzivisa nzeve kuboora, kuboora muviri, jekiseni mishonga, nyora munzvimbo ine mibvunzo kusabereka uye kusava noutsanana.
3. Vanhu vane hepatitis C utachiona pavaishanyira mazino kukiriniki, kana mumwe utano zvikoro vanosungirwa kuzivisa chiremba kuti munotakura utachiwana. Kutadza kuita kudaro pangozi dzakawanda vashanyi kuti mazino kuchipatara.
4. Chero mavanga kana abrasions vanofanira kunyatsoongorora kubata disinfectant mhinduro ugoafukidza pamusoro mvura isapinda bhandeji.
5. Persons rine vakawanda pabonde, kushandisa chipingamupinyi nzira pamuviri, zvakadai makondomu, kushomeka mukana wokutapukirwa nokuda hepatitis C utachiona uye zvimwe zvirwere zviri kuburikidza kurara kuonana.
6. Zvakakosha kuita matanho zvainanga yakachengeteka nzira kushandisa midziyo kuti jekiseni, majekiseni, nyora uye zvimwe zvinhu.

Zvinonzi kunzwisisa kuti hepatitis C utachiona haina kuburikidza kusiri kuonana. Kugwinha maoko, kutsvoda uye kumbundirwa ndokuchengetwa, umo nyaya hapana chikonzero kushandisa voga kurapa kana tichishanda varwere utachiona. Contacts, izvo zvinowedzera mukana yedzimudzangara, nguva dzose pamwe nokubudiswa ropa.