Pari, maererano World Health Organization, chikuru chinzvimbo pamazita kwezvirwere kuti kukonzera rufu munhu, utore zvokurwara pakati kumwoyo, zvishoma nezvishoma kuwedzera kunaka upenyu uye kutungamirira vanozokunda kukundwa dzose dzimwe nhengo dzomukati.
The yapera dambudziko
Saka pane neBP uye atherosclerosis muchiridzira anenge ose wechipiri mukuru, kunyanya pashure pemakore makumi mana. Vanhu vazhinji vanotaura zvirwere izvi zviri zvachero chaizvo, achitsanangura kuwanda kwavo uye sei zvinoita kuti ngozi. Zvisinei, rufu mutobvu yematambudziko. Uyu myocardial infarction, ischemic uye Hemorrhagic sitiroko, kutsemuka aneurysm, cardiac uye renal kukundikana. BP uye atherosclerosis kazhinji pamwe mumwe sezvo wokutanga vavo nguva inotyora nhumbi trofiku, zvichitungamirira pakupedzisira kune wechipiri.
Zvinoitwa pharmacological boka
Rakajairika kurapwa nokuti kufurirwa nemishonga ndivo diuretics - zvinodhaka zvinowedzera weti uye nokudaro achidzikisa ropa vhoriyamu uye kumanikidzwa midziyo. Saka, varwere vane chirwere cheBP navo zvakananga zvairatidza. "Indapamide MI STADA" "Indap" "Akripamid" "Arindap" "Arifon", "Ravel" - zita iroro zvinodhaka kutengeserana, sezvo mishonga aya akaita pachishandiswa imwe vanoshingaira fuma - indapamide, uye akasiyana chete mukugadzira makambani, upiyona hwebetsero uye Chokwadi, mutengo. Ivo chokuita pharmacological boka thiazide diuretics, izvo, kusiyana loop ( "Furosemide", ethacrynic acid, "bumetanide") asingadi nhaka diuretic chiito chakadaro simba, asi zvisinei neBP iri mune zvinoratidza dzavo. "Indapamide" uye ane zvakawanda zvimwe zvinokonzerwa.
kubatsira zvinodhaka
It runogonesa kuti elasticity rwengarava ropa, nokudaro achidzikisa zvachose peripheral nemishonga. Izvi zvinotungamirira zvinozoita kuti vasanyanye mutoro kuruboshwe ventricle mwoyo uye anobvumira kuti zvishoma tisawirirane munguva kudzingwa danho. Izvi imhaka mano indapamide yakadai ichivharira zvokusarudza ari kunonoka chokufambisa migero kuti calcium, pasina iro vasospasm wakagumiswa. It kunoderedza vascular aikanganiswa catecholamines, kuchikonzera marwadzo avo masvingo, uye kunokurudzira relaxant yavo - prostaglandin E2. Muchiitiko chino, indapamide haana kumbochinja lipid uye carbohydrate muviri, rinogona kushandiswa varwere cheshuga. Saka, ine siyana zvinokonzerwa kumwoyo, kwamakadarika "Indapamide" zvairatidza yokushandisa anosanganisira dzinoti kunokosha neBP, inzira inobudirira mushonga uye kunoderedza ngozi mwoyo kurwisa uye sitiroko.
neizvi divi
Chokwadi, kufanana chero mushonga, rine kwete chete uchapupu pakushandisa "Indapamide" asi contraindications, izvo chokuita ine zvakakwana vazhinji nemishonga. Chokutanga, zvinokanganisawo nechepakati tsinga, zvichikonzera vaingoerekana kutya uye kushatirwa, kufunganya, nomusoro uye dzungu, hope kana, Ukuwo, kushaya hope (nerimwe murwere), zvinoita mwoyo, kurukutika. Ndapera nokuda chinovhiringidza zviri catecholamines angava kutyora mwoyo mutinhimira, izvo vachaonekwa palpitations. Uyewo, nokuda usinganyanyi diuretic kushanda uye indapamide kurasikirwa weti kwete yavaibvisa chete uye kuiisa chlorine, asi potassium uye magnesium zvingamuka gipokaliemicheskogo syndrome.
Impact pamusoro nhego nehurongwa
Uyewo mushonga uyu chinobata zvomudumbu vanhu hurongwa, kuchikonzera kuda kurutsa, kurutsa, abdominal marwadzo, kurasikirwa kudya kusvikira neanorexia, dyspeptic zvirwere chetsoka (manyoka / kupatira). Kashoma zvinogoneka anogumbura kuchinja mucous membranes ari kufema turakiti pamwe kukura chikosoro, rhinitis, pharyngitis uye sinusitis. Uye nokuda zvakananga zviito indapamide murwere vachaona kuita weti kakawanda, kusanganisira usiku, uye kunzwa kuoma mumuromo (polyuria, nocturia). In pamberi kugadzikana sema chinzvimbo murwere kana hypersensitivity kuti mushonga kunogona kuitika chete kuvaviwa mapundu, urticaria, kana kutonzwa Hemorrhagic vasculitis. Zviri apo neapo, asi chiri kuratidzwa indapamide nomugumisiro evanhu hematopoietic hurongwa muchimiro hemolytic kupererwa, leukopenia kana thrombocytopenia, agranulocytosis, mwongo aplasia tishu.
Contraindications
Nokuda kurutivi zvinokonzerwa zvinodhaka yakarurama contraindications kuti kushandiswa kwayo akataurwa hepatic kana renal insufficiency, hypersensitivity mumwe zvokubikisa kupinda kwayo sezvamunoita, yokupara zera (Makore 18), hypokalemia (zvisinei nezvekwakabva), mamiriro gestation kana lactation kumwedzi. Uyezve, akaipisisa hanya kugadzirira rinoshandiswa panoongororwa kutyorwa mvura-electrolyte dzakagadzikana renal kana hepatic basa, hyperparathyroidism, chirwere cheshuga (decompensated Danho), hyperuricemia (kunyanya nechirwere pamusoro gout kana uric iine acid nephrolithiasis). Zvinokoshawo kufunga zvazvinoita kwayo mubatanidzwa kurapa chirwere chacho.
Achingwarira!
Kazhinji zvakakwana chipimo chemushonga zuva zvinodhaka nenzira dzinoverengeka "Indapamide" mapiritsi. Zvairatidza kuti kushandiswa kwezvinodhaka - chirwere cheBP uye mwoyo nokukundikana. Vari kubatwa kuzvivako, uye saka zvinokosha kuti zvakanaka chokubatanidza zvinodhaka pamwe chete. Kana murwere, kunyanya vakwegura, anogamuchira cardiac glycosides kana laxatives, zvinoda kuramba zvichiongororwa kreatinemii uye potassium uyewo yavaibvisa uye magnesium yomuropa, shuga uye uric asidhi muropa plasma. nezviyero zvose izvi chokudzivirira chinangwa mukudzivirira kukura chakasimba renal kukundikana kana zvakakomba kutyorwa electrolyte mwero. Zvinofanira kurangarirwa kuti zvinodhaka izvi ane mucherechedzo hypotensive chaizvoizvo, asi nokuti kunogona kuderedza wevasungwa mano kwevanhu, zvokuti haufaniri kutyaira motokari pashure pokutora "Indapamide".
zvakawanikwa
Saka, pasinei nokuti mushonga une zvakawanda nemishonga uye kuderedza zvezvinotaurwa zvairatidza kuti kushandiswa, "Indapamide" chiri kwazvo inobudirira pakurapa zvinokosha neBP uye yechipiri neBP. Izvi imhaka vakawanda nzvimbo yaro pharmacological basa, nokukurumidza uye apedzise absorbability wayo kubva nemudumbu, uyewo kumusoro bioavailability. Unhu izvi kuti imire kubva dzinoverengeka diuretics uye kuti rinokosha budiriro pakurapa zvirwere kumwoyo.