Nasal mwaya "Dezrinit": wongororo vanachiremba, mirayiridzo kushandiswa uye sezvamunoita

"Dezrinit" - chakaita zvokugadzirwa glucocorticosteroid (GCS) kukamura uchishandisa kushanda. The rinoita mumiririri ndiyo mometasone antiallergic uye antiinflammatory chiito. In nokushandisa mushonga mu mishonga kuti murege kukonzera systemic Migumisiro kuratidza yayo Anti-anogumbura kukamura uchishandisa basa. Funga nyaya iyi pamusoro "Dezrinit" gadziriro apindure n'anga uye vatengi.

The chinodhaka hwakaipa kusunungurwa anogumbura nevamiririri, wakawedzera kugadzirwa lipomodulin, ndiko inhibitor pamusoro phospholipase A, uye izvi imhaka rutapudzo yacho zvakasunungura arachidonic asidhi uye prostaglandin usage chinovhiringidza uye cyclic endoperoxides. The mushonga iri kudzivirira kuunganidza neutrophils, kuderedza kugadzirwa anogumbura exudate uye lymphokine, chinovhiringidza pamusoro macrophage kutama, nokuderedza granulation pezvakaitwa uye infiltration, kuderedza paumbwe chemotaxis, kureva kunyatsobatsira paya sema maitiro kunoitika kumisa kukura pakarepo sema kuita.

Izvi zvinosimbiswa pamusoro medicament "Dezrinit 'wongororo vanachiremba - unyanzvi mumunda mavo. The mamiriro rinoreva zvinosanganisira mometasone furoate uye upiyona hwebetsero.

Pharmacokinetics

Intranasal kushanda kunoita systemic bioavailability kuti mometasone furoate kuti asingasviki 1%. Active fuma kukwanisa kupinda ropa, riri diki zvakawanda zvokuita uye kushingaira biotransformed pashure yokutanga Pfuurai chiropa. On kugadzirira "Dezrinit" Doctors ongororo vainyanya zvakanaka.

Zvinoratidzwa nokuti:

• pakurapa perennial uye pamwaka sema rhinitis vana 2 makore uye vakuru vakuru;
• chenjera sinusitis, exacerbation echirwere sinusitis vana makore gumi nemaviri uye vakwegura, uye vakuru (kusanganisira vakwegura) sechinhu adjuvant mishonga;
• Mabatirwo adenoids muvana kana vakuru nasal polyposis;
• kudzivirira pamwaka sema rhinitis mune mwero uye kwazvo ezvinhu vana kubva zera nemaviri uye vakura uyewo vakuru. Mufambiro akakurudzira kwevhiki ina risati ratanga mwaka dusting.

kusunungurwa Form

Metered nasal pfapfaidzo. Mumwe chinu rine 140 mishonga. The duramazwi chimiro zvinodhaka ari muchimiro mumate husiri panguva gadziriro bhuku. Dzakakodzera "Dezrinit" vana. Reviews vanachiremba ngaadarowo.

The nzira kushandiswa uye mirayiridzo kushandiswa

The mushonga chinotarisirwa intranasally. Pfapfaidzo huri chinu iri jekiseni kupinda mhino uchishandisa rinokosha dosing mudziyo.

Risati ratanga kushanda pfapfaidzo kuita 10 bvunzo taps on dosing mudziyo. Mushure calibration, mishonga pakukurukura mwero wakaisirwa mumwe wokudhinda akakungurutsa kuturika 100 MG raiva 50 mcg kuti mometasone. Asati kushandisa chigadzirwa pashure dzinopfuura 14-zuva rotonhorera, kuti calibration chinofanira kuramba. Mumwe Chikumbiro kunofanira kubatana yavaizofanoshandisa kuzunungusa chinu.

nemishonga

About "Dezrinit» Kugadzirira dzokurapwa wongororo anoratidza zvinotevera zvingakonzerwa nemishonga:

• yemaziso;
• hypersensitivity kuita kusanganisira dyspnea, uye bronchospasm;
• anaphylaxis;
• nomusoro mune vana nevakuru;
• angioedema;
• nosebleeds;
• kunopisa nasal mhango;
• vana tinganetseka kukakanganiswa kukura, psychomotor wokusagadzikana, hope zvirwere, kufunganya, kwakakasharara, kuora mwoyo;
• zvikuru huro;
• perforation of nasal septum ;
• kunzwa kuzvinetsa pamusoro mucous iri nasal mhango;
• kutekenyedzwa pharyngeal mucosa bundu;
• yokumusoro kufema turakiti zvirwere;
• sneezing;
• ngazvirege kutongoravira chainetsa;
• kutyora kunhuhwidza;
• tsanga;
• rikakura intraocular kumanikidzwa;
• ulceration of mucosa iri nasal mhango.

Contraindications

Drug "Dezrinit" (wongororo vanachiremba ngaadarowo) iri contraindicated mu:

• hypersensitivity kuti mometasone kana chezvinonhuwira kuti idzidziso;
• .. A achangopfuura kuvhiya kupindira kana nasal kunotevera kuti muchikuvadza kuporeswa, kuti Anoshandira GCS inhibitory netsika panguva kuporesa pezvakaitwa;
• Vana (kana nasal polyposis 18; chakasimba exacerbations echirwere sinusitis, chenjera kana kusvika makore 12; makore 2 rhinitis pamwe perennial uye pamwaka sema).

Kushandisa zvinodhaka panguva yepamuviri uye achiyamwa

Kunyanya hapana Zvidzidzo vakachengeteka kushandiswa "Dezrinita" panguva yepamuviri uye lactation chaiitirwa. mushonga uyu anofanira kuzviita kuti achiyamwa nevakadzi pamuviri chete kana zveutano amai kusapfuudza zvinogona ngozi kuti mwana kana mudumbu. Vachangoberekwa vevanaamai vaishandisa corticosteroids panguva pamuviri, unofanira kupfuura munhu kuongorora chaiyo kuziva zvinoita hypoadrenalism. Izvi zvinosimbiswa pamusoro medicament "Dezrinit" wongororo dzokurapa immunology.

Kushandisa zvinodhaka vana

Kushandiswa "Dezrinita" iri contraindicated muvana vane nasal polyposis mhango 18; chinhu exacerbation echirwere sinusitis kana rikwanise chimiro makore anosvika 12; pamwe perennial uye pamwaka sema rhinitis kusvika 2 years. Aiwanzoshandisa "Dezrinit" iri adenoids vana. Reviews vanachiremba panyaya iyi akanaka.

mirayiridzo kushandiswa

Zviratidzo atrophy of nasal mucosa pashure pakurapa rimwe gore (mwedzi 12) havana kuchengetwa. Kudzidza biopsies ose nasal mucosa vakaratidza zvakakonzerwa mometasone kuti zvinoitwa normalization kuti histology. Long kushandisa zvinodhaka, uyewo kurapwa kwenguva refu refu, kunosanganisira nenguva dzirikure inspections nasal mucosa chiremba otorhinolaryngology.

In tibhii yemweya (Isimba rakadini rinogona kubudiswa kana rinobata); kwemabhakitiriya, systemic nemavhairasi (kusanganisira herpes kunokanganisa maziso, kana kupisa nokuvava simplex) kana fungal chirwere; refu utsinye corticosteroids; kuvapo untreated vemunyika noutachiona pamusoro nasal mucosa, uyewo achiyamwa uye pamuviri, mushonga unofanira taurira nokungwarira.

Treatment rinoreva "Dezrinit" akakurudzira mira uye kutanga kuita chinokosha kurapa kukura vomunharaunda fungal noutachiona pamusoro pharynx kana mhuno.

Kutsamwa ari pharynx uye nasal mhango, izvo anoramba kwenguva refu zvikuru nguva, zvinogona kunzi chiratidzo nokuda kukundikana chezvinodhaka. Unogonawo kuona kuti hazvina kukuzarurira kudzvinyirira ari hypothalamic-pituitary-adrenal hurongwa pashure kushandiswa kwenguva yakareba zvinodhaka. Izvi runoratidzwa wongororo kugadzirira "Dezrinit".

Special pfungwa roga zvinoda varwere kugamuchira refu kurapwa pamwe corticosteroids, achipfuura kurapwa pamwe mometasone. Kana kubvisa GCS hurongwa chiito, zvino mukana tinogona kutaura kuti achaita kusava adrenal basa, mishonga izvo zvinoda matanho akakodzera.

Mune vamwe varwere, yezwi mometasone kurapwa mushure corticosteroids zvingaitika ucharwadziwa systemic kushandisa glucocorticosteroids. Izvi zvinosanganisira kuora mwoyo, kurukutika, kurwadziwa tsandanyama uye / kana majoini. Varwere vanoda anokosha agutsikane kuti kurapwa ne "Dezrinit" zvakakodzera, pasinei zvinoderedza kwokuomerwa zviratidzo nasal mucosa maronda. Masked (asi kwatova murwere) Mabatirwo glucocorticoid systemic sema zvirwere zvakadai eczema uye conjunctivitis, zvinogona kuzvibatanidza yezwi omunharaunda corticosteroids.

In pakurapa yaitsigira divi polyps; polyps, izvo chokuita cystic fibrosis, uye polyps, zvachose kufukidza nasal mhango, vakachengeteka uye efficacy kuti "Dezrinita" harina kudzidza. Ropa uye yaitsigira divi polyps ane mugari chimiro, zvakakodzera kuongororazve.

Varwere kugamuchira kurapa nokuda corticosteroids, kuwana akaderedza zvirwere reactivity uye saka tinofanira kuyambira kuti kuwedzera mukana wokutapukirwa kuburikidza kuonana gwirikwiti vanorwara, huku pox uye zvimwe zvirwere zvakaita chirwere, uye kudiwa kubvunza nyanzvi, kana kuonana murwere achiri ndakatora nzvimbo.

Refu kushandiswa corticosteroids nasal huru mishonga inogona anowedzera kukura nemishonga. Zvisinei, migumisiro izvi zvinogona kuva kure kashoma kupfuura apo systemic corticosteroids zvinoshandiswa, uye dzinosiyana munzvimbo varwere nomumwe. Anotarisirwa systemic Migumisiro zvingasanganisira chirwere Cushing raMwari, iro kunoratidzwa adrenal kudzvinyirira, yemaziso, tsanga, kukura retardation kuvana nevechidiki, uye dzimwe nguva dzinoverengeka maitiro uye mupfungwa zvinokonzerwa, kusanganisira mwoyo, hope chinovanetsa, mwoyo kana utsinye, psychomotor wokusagadzikana.

Kana mushonga kudyidzana pakati zvinodhaka zvakasiyana pamwe mometasone, pamusoro tsvakurudzo iyi inoitwa.

Nasal pfapfaidzo «din email Dezrinit": kutenga wongororo uye vanachiremba

Reviews kugadzirira yakawanda zvakanaka. rubatsiro zvakanaka sema rhinitis. Kazhinji akashivirira kashoma kupa nemishonga. Vana vaduku chinobetsera adenoids, zvinoderedza kuzvimba. Chinhu chikuru kuremekedza mirayiridzo kushandiswa.