"Nalbuphine": kurairirwa, description, akafanana, wongororo

Zvichirwadza ... zvichirwadza ... Hakuna mumwe munhu asingadi kutaura mazwi aya. Kana tine chimwe chinhu kuchirwadza, nezvimwe zvinetso zvose panzvimbo yechipiri. Anokosha uye chinonyanya kukosha panguva ino - kuti kusagadzikana akanyangarika.

Modern Pharmacy akagadzirira kupa vatengi ayo guru uwandu pamusoro rufimbi zvinodhaka zvakasiyana nenheyo kuita. Imwe mishonga yakadaro "nalbuphine." Instruction inodzora sechiratidzo agonist uye opioid Kanotokonya antagonist, munhu marwadzo unonyaradza marwadzo, vanobatanidzwa ndandanda rechitatu mazita marwadzo zvinodhaka.

Kuronga uye pharmacodynamics

Huru vanoshingaira chirungiso "Nalbuphine" ndiyo nalbuphine hydrochloride. The mushonga ndiwo mushonga unonyaradza marwadzo opioid boka (zvinodhaka kuti anopa simba iri muviri womunhu, rakafanana kuitwa chinodhaka). Nheyo zviito zvinodhaka "nalbuphine" mirayiridzo application rinoti zvinotevera: huru kushingaira chirungiso kuchititadzisa nokupfuuridzirwa marwadzo nomunhu pakati Tutsinga tunofambisa mashoko utwu munyika tsinga. The mushonga kunomutsa dzakanga zvikamu uropi, nokudaro richichinja mupfungwa maonero kurwadziwa.

Zvazvakaita "Nalbuphine" pamusoro womunhu muviri akafanana mugumisiro "Morphine". Nalbuphine hydrochloride zvinoita kurutsa centre, anokwanisa kudzvinyirira vakaumbwa hunenge, ane kunyaradza zvikuru. Mishonga anovanza kufema centre, asi pamwero muduku zvikuru kupfuura "Morphine", "Promedol" kana "Fentanyl".

Release chimiro uye chipimo chemushonga zvaiitwa

Manufacturers kupa vatengi vavo mushonga mu ndiro "nalbuphine 10" uye "20 nalbuphine." Mumwe ampoule - 1 ml medicament. Wokutanga ( "nalbuphine 10") dzaizara ari remidzanga 10 ndiro, uye wechipiri - kusvika 5. "Nalbuphine" (mhinduro) mirayiridzo kushandiswa, nenyanzvi chaivo utano dzinokurudzira kugadza tisingatauri nomumwe zano, zvichienderana uremu muviri, nekuomarara kurwadziwa munyaya zvirwere.

The medicament anogona kupiwa nomutsinga, intramuscularly kana subcutaneously. A chete dose kuti akura munhu Ingasiyana kubva 100 .mu.g 1 MG chete makirogiramu muviri uremu. The kwokutanga dose mwana - haasi anopfuura 300 g pa 1 kg kurema muviri. The kakawanda pokushandisa medicament kunobva zvachose kunotoda mufananidzo. The kosi kurapwa haafaniri kugara mazuva anopfuura 3-4, sezvo mushonga ari marwadzo, uye kwenguva yakareba vaitarira kungava muropa.

Zvairatidza kuti kushandiswa "Nalbuphine"

"Nalbuphine" mirayiridzo Chinyorwa rinokurudzira tichiwana simba marwadzo syndromes kuti anogona nechokuita postoperative nguva, gynecological zvomusejari kupindira pakurapa mwoyo kurwiswa uye kenza.

Uyewo, mishonga iri kushandiswa munyaya (gadziriro murwere kuti vakawanda yokutindivadza uye kuvhiya pre-mushonga) prednarkoznoy premedication. Chaizvoizvo, chinangwa chikuru nzira iyi - kuderedza mwero mwoyo murwere uye nokusimbaradza kuita zvinodhaka nokuda yokutindivadza. Kutaura zvazviri, izvi chikuru nzvimbo kushanda kuti nalbuphine hydrochloride.

Ndiani haafaniri kutora?

"Nalbuphine" mirayiridzo, inofambiswa uye nyanzvi zano vanorambidzwa kubvuma varwere zvikuru hypersensitivity kune huru vanoshingaira chirungiso. Inadmissible kushandiswa medicament nokuda pakurapa varwere vanenge ose zvirwere chiropa uye neitsvo. Izvi imhaka yokuti rinoita "Nalbuphine" iri chiropa. The kutanga chimiro medicament inenge yabudiswa muna weti (70%) muchimiro nomukaka yabudiswa muna bile.

No mushonga raitongwa varwere vane doro uye zvinodhaka nedoro. Pasina kudiwa mishonga haina varumbidzwa dzokushandisa vana. Sezvo "nalbuphine" ane simba pamusoro pemasimba nzvimbo uropi, haisi varumbidzwa panguva kurapa varwere mupfungwa kusagadzikana (nokuti psychosis, kuora mwoyo uye zvichingodaro. N.).

Spillover maturo "Nalbuphine"

"Nalbuphine", kushandiswa chiri kukonzerwa kufurirwa marwadzo pamusoro womunhu, anogona kukonzera vamwe divi migumisiro kubva siyana hurongwa nenyere. Saka, kumwoyo anokwanisa kupindura kushanda medicament kukura tachycardia, arrhythmias, BP nokufamba.

Kubva tsinga kungaita nomusoro, ane simba kunyaradza mugumisiro (lethargy), euphoria. Kune vanoziva remangwana kana zvinofunga kuratidzwa akadai wokusagadzikana, vakawedzera mwoyo. Nemudumbu anogona kuyeuchidza pachako kuratidzwa dyspepsia (fufune ose).

Mune zvimwe zviitiko, mishonga 'nalbuphine "(Chinyorwa rine mirayiridzo inokosha) anogona kukonzera zvakasiyana neutachiona (anaphylaxis yaisanganisira).

Uye, sezvambotaurwa, "nalbuphine" - munhu marwadzo chinodhaka, saka anogona kukonzera kwajairika.

Kunwisa mishonga

Chipimo chemushonga medicament Kuomerera mumwe nomumwe nomumwe murwere dose anosarudzwa zvichienderana mukuru ezvinhu, nekuomarara marwadzo, uremu uye zvichingodaro. N. Vakaparadzana kushandisirwa pasina chiremba cherechedzo kunogona kutungamirira overdosing. Muchiitiko chino, sezvinoita mutemo, pane zvinotevera zviratidzo: mwoyo pamusoro nechepakati tsinga, lethargy, dysphoria (zita rokupikisa "euphoria" vanorwara akaora mwoyo, kuratidza pacharo mu kushatirwa, mukupesana vamwe, kudekara yaiparadza, kakawanda manzwiro panomuka). Ovhadhozi zvinogona atadze kushanda zvakanaka pamusoro kufema centre.

Treatment kunoratidzwa kushanda mushonga (nokuti "Nalbuphine", kana akawanda opioids - iri "Naloxone"), gastric lavage uye symptomatic kurapa.

Pamuviri mums ...

Kana pamuviri ndiko kugadza "nalbuphine" mirayiridzo kunoita chete zvachose zvairatidza. Nokunyatsongwarira Mushonga Nachiremba mushonga vakurumidze kuberekwa uye zviitiko apo pane fungidziro fetus umbishi. Zviito izvi zvine chokuita kuti "nalbuphine" zvakakwana nyore inopfuura ari placental mechidziro zvinogona kukonzera kufema mwoyo vari neonate.

Ainyatsotsanangurirwawo chaizvo akataura mushonga paanenge achiyamwa, kunyange zvazvo "Nalbuphine" uye dzinounzwa pamwe mukaka waamai mune mishonga duku, vasina chiremba kukosha (asingasviki 1% yose inowanwa raitongwa chinodhaka). Kunyange zvakadaro, hapana chikonzero pangozi mwana pasina chikonzero chakakura.

mirayiridzo Special

A mhinduro jekiseni rine ayo sezvamunoita 10 MG / ml nalbuphine hydrochloride ( "nalbuphine Farmeks"), Chinyorwa rinokurudzira nokungwarira zvikuru kushandiswa kusagadzikana kufema basa, sezvo anogona kuderedza uwandu miniti vhoriyamu kufema 25%. Aidzorwa chiremba anofanira kuva varwere vachitora "nalbuphine" uye zvaivapowo kutambura uremia uye kwazvo chimiro kwekwashi, uyewo vakwegura.

Nokuti varwere insufficiency mishonga renal kana hepatic nokungwarira uye zvakasimba nomumwe metered. Zvinofanira kuva zvinobvira nokukurumidza kumira "Nalbuphine" nokuda muchikwata ichi wevarwere.

With renyevero Mushonga Nachiremba zvinodhaka kuti vanhu vane kukuvara dehenya, sezvo pane mukana wokuti nekukudziridza kufema mwoyo kwacho. A anodiwa kwazvo chokubatanidza kushandiswa "Nalbuphine" nevamwe analgesics, nokuda zvichibvira kwakaderera analgesia.

Under chenguva wezvokurapa cherechedzo uye mishonga duku mushonga inoshandiswa pakanyorwa narcosis, akarara mishonga, anxiolytics, antidepressants uye neuroleptics. Izvi "munzvimbo" kungakonzera kunyanya mwoyo pamusoro nechepakati tsinga uye kufema kuora mwoyo pakati basa.

Zvokungwarira "Nalbuphine" riri basa kuti negashiro varwere ambulatory, izvo inotongwa mugwagwa, kana avo vane basa chokuita mwero psychomotor siyana.

mutengo dungwerungwe

Mutengo siyana rakafara zvokuti "nalbuphine" chinodhaka. Mirayiridzo yokushandisa zvinodhaka mutengo uchapupu kuti mushonga uri kudiwa pakati vatengi. Uyezve unonyaradza marwadzo akagadza pacharo sezvo anobudirira mushonga mu nevashandi vezveutano. Product pasuru "nalbuphine 20" (5 ndiro) zvinokwanisika kutenga mu Pharmacies Russia kuti mari iri zvinobva 620 kusvika 810 rubles. "Nalbuphine 10" achaita mari kubva 650 kusvika 690 rubles (remidzanga 10 ndiro).

Mune dzimwe Pharmacies chinogona kuoneka pasero "Nalbuphine" iri sirinji (10 MG / 1 Rine mamiririta), akaronga kuti chete jekiseni. Mari nzira iyi yokusunungurwa iri kumativi 160 rubles.

Kudyidzana nevamwe zvinodhaka

Sezvambotaurwa, "Nalbuphine" (User chine mashoko akadaro) pamwe antidepressants, anxiolytics, neuroleptics, hypnotics, rufimbi vamiririri, zvinodhaka antihistaminic ane kunyaradza zvazviri, kunonatsiridza panyaya iyi depressant zvainoita nechepakati tsinga. Kushandisa unonyaradza marwadzo kufanana kuti penicillin nomukaka uye phenothiazine zvinogona kukonzera amplification kuti svoto uye kurutsa.

"Naloxone" (mushonga) kuchaderedza mugumisiro yokuwana opioids uye saka kuderedza kufema mwoyo uye CNS mabasa muitiro akaparirwa "Nalbuphine".

"Naltrexone" Sezvineiwo mhanyisa chimiro zviratidzo kudzimwa pamusoro pakanyorwa kupindwa muropa ( "pakubwinya kwayo zvose" Zviratidzo kuonekwe pashure 5 chete maminitsi pashure kwokubatsira zvinodhaka, acharamba maawa 48). Symptomatology akatsiga zvikuru, zvakaoma zvikuru kuti kubvisa.

Zvinofungwa vatengi uye nyanzvi utano

Varwere nezvazvo "nalbuphine" sechinhu kumbonyanya anobudirira mushonga munguva pashure zvomusejari kupindira mune oncology. Kunyange zvazvo migumisiro inokonzerwa vari zvakajairika mazuva uye anowanzoshandurwa runoratidzwa musoro, hope, kusakendenga, zvomudumbu nenyonganiso. Maererano vanachiremba, "nalbuphine" (Murayiro, murwiyo ari medicament, nheyo matambudziko pamusoro apa) wakanaka unonyaradza marwadzo kuti chirwere zvakakwana chakakomba chokuita zvikuru kurwadziwa.

Pane imwe chikamu zvinodhaka vanoshandisa - muropa nezvinodhaka. Pano, dzekutora wongororo vari kuderedzwa kumubvunzo kana chiito zvakafanana "Nalbuphine" uye "Morphine". Kubva zvose, sezvinoratidzwa boka iri vatengi, zvinganzi vakagumisa kuti rikwezve muropa nezvinodhaka kuti "nalbuphine" mutengo (Chinyorwa kukarukureta pavarwere akadaro hazvitombobvumidzwi). The mushonga iri (zvinodhaka yakati zvakaoma) chisingakoshi, inogona Zvisinei kutengwa chero chemishonga, zvichienderana resipi. Zvisinei, mumashoko avo, "mukuru chibhende, asi kwemasikati-kumusoro kupfuura chaihwo."

Kubva apa zvinogona akagumisa kuti "nalbuphine," Chokwadi, munhu chaizvo unonyaradza marwadzo. Zvisinei, zviri kutengeswa chete mushonga - uye zvakarurama kudaro. Sezvo nomumwe akasarudza chiremba chipimo chemushonga uye kwadzinoita chikumbiro - kuvimbisa kuti kubata zvinodhaka mumuviri murwere vachava netariro, uye ngozi nemishonga - mashoma.