Mirayiridzo kushandiswa "Flosterona": chipimo chemushonga, contraindications, analogs

"Flosteron" - mumwe mushonga, iyo inobatsira zvishoma kusunungurwa interkleykinov 1 uye 2, uye interferon-wegamma kubva macrophages uye lymphocytes. The medicament rine immunosuppressive, antitoxic, antishock, antiinflammatory, antiallergic uye antiinflammatory kushanda.

Medicine "Flosteron" mirayiridzo kushandiswa kuri pachena kuti vose, kuchititadzisa kusunungurwa pituitary Beta lipotropina uye AKGT. Asi ichi hachisi zvinoderedza achiparadzira kwevari Beta-endorphin. Uyewo, kuti zvinodhaka kuchititadzisa ari secretion pamusoro FSH uye TSH.

The medicament "Flosteron" anowedzera excitability ari nechepakati tsinga, apo kuderedza eosinophils uye lymphocytes. Kugadzirira kunowedzera nhamba masero matsvuku eropa, kuti kukurudzira kugadzirwa erythropoietin.

Medicament "Flosteron" zvairatidza yokushandisa zviri siyana chaizvo, interacts pamwe cytoplasmic chaizvo receptors. Somugumisiro, mumwe kunzwisisa aumbwa, anokwanisa kupinda muchitokisi neerekitironi zvokonzera mRNA usage, mapuroteni kuti induces paumbwe uye lipocortin. fuma iyi kuchititadzisa phospholipase A2, nokudaro zvichivhiringidza kusunungurwa arachidonic acid. Uyewo Lipokortin chinonditadzisa synthesized zvinoriumba zvakadai leukotrienes, prostagladin uye endoperoxides kuti zvinoshingaira kutsigira panowanikwa neutachiona uye anogumbura kwendangariro.

"Flosteron": zvairatidza yokushandisa

Majekiseni zvinodhaka waakaudzwa kurwisa mhando dzakasiyana nehana: anaphylactic, ropa, cardiogenic, chepfu, operative, zvinorwadza, apise. Uyezve, kushandisa "Flosteron" rinoshandiswa kana ane anaphylactoid siyana :

1. Cerebral edema mu namamota kana pashure pokuvhiyiwa, musoro kunotevera, uye nemwaranzi kurapa.
2. Árbol asima kwazvo chimiro.
3. Zvirwere connective munyama.
4. Lupus erythematosus.
5. Dzinonzi rheumatoid arthritis.
6. Chenjera renal kukundikana.
7. Kusvibisa pamwe cauterizing mvura.
8. Hepatic pakoma.
9. Chenjera chiropa.
10. Thyrotoxic dambudziko.

Rinoreva "Flosteron" (majekiseni) inowanzoshandiswa intra-articularly. kurapa kwakadaro chinoshandiswa kurwa osteoarthritis, chirwere Reiter, ankylosing spondylitis, psoriatic uye dzinonzi rheumatoid arthritis.

The mushonga pamahwandefa

"Flosteron" mirayiridzo kushandiswa kunoda kunyatsodzidza, inowanika kwete chete muchimiro majekiseni, asi pamahwendefa. Vari kazhinji ushandiswe apo zvinotevera zvirwere:

1. Lupus erythematosus.
2. Kusagadzikana connective munyama.
3. Periarthritis nodosa.
4. Scleroderma.
5. Dzinonzi rheumatoid arthritis.
6. Dermatomyositis.
7. Chirwere uye chenjera anogumbura pezvakaitwa mu majoini.
8. Psoriatic chearthritis uye gout.
9. Ankylosing spondylitis.
10. Juvenile chearthritis.
11. Humeroscapular nodosa.
12. Osteoarthritis.
13. Polyarthritis.
14. Kunyange ndicho chirwere, asi chete nedzevakuru.
15. Non-chaicho tenosynovitis.
16. Bursitis.
17. Epicondylitis uye synovitis.
18. Rheumatic mwoyo chirwere.
19. Chenjera rheumatic fivha.
20. Chorea.
21. Chirwere uye chenjera sema zvirwere.
22. Árbol asima.
23. Drug nekumhanyirira.
24. Serum chirwere.

The medicament "Flosteron" Mahwendefa kurongera kubata zvimwe zvirwere ganda, zvakadai kuonana dermatitis, eczema, atopic, exfoliative, seborrheic dermatitis uye bullous herpetiformis, hunokachidza epidermal necrolysis uye Stevens-Johnson.

Uyewo, kuti mushonga chimiro ichi rinoshandiswa kunzwisisa kurapa pamusoro chepfungwa edema, izvo zvinogona metastatic, zvinorwadza uye postoperative (pashure pre-parenterally). Kuzvigona zvinodhaka uye sema zvirwere ziso Somuenzaniso, cornea urikanwi, sema conjunctivitis chimiro uye vamwe anogumbura zvirwere, kusanganisira tsitsi ophthalmitis, optic neuritis uye zvakafanana.

Medicament "Flosteron" mirayiridzo kane uwane mazita zvairatidza kuti kushandiswa, kunoita kuti kubvisa dzisiri uye chikuru adrenal insufficiency, kunyange pashure kwavo rokubvisa. Anorwa zvinodhaka uye itsvo zvirwere: rikwanise glomerulonephritis, nephritic syndrome.

Zvirwere ropa

The mushonga pamahwandefa nachiremba vamwe yokutyora mubasa ropa: tsvuku muchitokisi kupererwa, mune mamwe mashoko - erythroblastopenia; thrombocytopenia yechipiri, asi chete vakuru; thrombocytopenic purpura; Hodgkin nehosha; chenjera myeloid uye lymphoid neleukemia; vachiberekwa aplastic kupererwa neropa; autoimmune hemolytic kupererwa neropa; agranulocytosis nezvimwe zvirwere.

Iyo anobata pulmonary chirwere

Kakawanda vane zvirwere zvokufema kugadza "Flosteron". Mirayiridzo kushandiswa kwezvinodhaka kunoratidza kuti rinogona kushandiswa kenza yemapapu ari yaisanganisa mishonga. Panyaya iyi, iyo medicament chinotarisirwa akabatana cytostatics. Uyezve, murayiro kushandiswa "Flosterona" rine ruzivo nezvekuti mushonga unobatsira iri pakurwisana urwere Leffler. Zvinonzi nezvaro chirwere ichi chete kana dzimwewo nzira regai kubatsira. Uyewo, kuti mushonga rinowanzoshandiswa borreliosis, pulmonary tibhii, tuberculous yomumuzongoza uye chido nemabayo akabatana mishonga.

Contraindications pakushandisa gadziriro

Usage "Flosterona" mirayiridzo inopa kuti mushonga mu systemic kurapa ane zvimwe contraindications. Pakati pavo pane zvinotevera: chirwere cheshuga, rikwanise psychosis, congestive mwoyo kukundikana, achangopfuura myocardial infarction, gastritis, esophagitis, diverticulitis, peptic urikanwi zvirwere chakasimba, vanoshingaira muchimiro tibhii pasina zvimwe marapiro, immunodeficiency, vakafungira kana yakasimbiswa strongyloidiasis , gwirikwiti, huku pox, systemic mycoses.

Contraindications nokuti pakatanga kupinda

Drug "Flosteron" (Chinyorwa rine zvose zvakafanira mashoko) rine mamwe contraindications. The medicament haagoni kupinda kusagadzikana pane majoini, pathological ropa kuti angava mugumisiro pakugamuchira anticoagulants. Jekiseni "Flosterona" hazvitenderwi pasi akaratidza periarticular osteoporosis, articular pakakuvara pfupa, uyewo kana ane utachiona lesion pfungwa intervertebral dzezvimwe, periarticular nyoro munyama.

Mune zvimwe zviitiko, haugoni kushandisa zvinodhaka nokuda kurapa ganda nezvimwe zvirwere

Kakawanda, mushonga "Flosteron" rinoshandiswa kurapa mamwe dermatitis. Zvisinei, muchiitiko ichi, pane contraindications. The mushonga haabvumirwi kubata rashes pamusoro pakanyorwa mutambo mapundu mu vacheche kusvikira gore rimwe, pamberi mushonga siyana. Uyezve, "Flosteron", mirayiridzo iyo application chinopa rondedzero yose contra-zvairatidza, haagoni kushandiswa pakurapa mburwa vulgaris, uyewo kuvapo kwezvirwere zvakadai sarcoma, xanthoma, hemangiomas, melanomas, atheroma, kenza ganda, fungal, nemavhairasi uye kwemabhakitiriya zvirwere ganda, herpes, trophic yakaderera gumbo urikanwi, iro kwamuka somugumisiro varicose mutsinga.

Haugoni kushandisa ndiro "Flosteron" zvirwere fungal nzeve uye meso, perforating eardrums nezvawagara myocardial kana chirwere otitis zvenhau, yemaziso, sclera, urema, corneal epithelium kana apo rive dete, zvirwere zvinokonzerwa noutachiona nzeve uye meso, tuberculous maronda nhengo idzi, uye chenjera nemavhairasi zvirwere, semuenzaniso, asingafungi keratitis.

Ndinogona kutora "Flosteron" pamuviri uye lactation

Maererano nenyanzvi, iri zvachose aidzora uye zvidzidzo zvakakwana munzvimbo iyi zvave inoitwa. Saka kutora ino chaiyo zvinodhaka anobvumirwa vakadzi vane pamuviri chete kana kubata mishonga iri kupfuura ngozi mwana asati aberekwa. Panguva iyoyowo, pane contraindications - preeclampsia, placental maronda zviratidzo eclampsia. Unogona kushandisa zvinodhaka ichi pamatunhu mishonga uye kwenguva yakareba.

With Panyaya kwokubatsira zvinodhaka intramuscularly, pakuitisa kwakaita tsuro vave dzinounzwa zvimwe abnormalities iri kusimukira mudumbu, kusanganisira cephalocele uye achiine rukuvhute heniya. The mushonga akapiwa chikamu C pamusoro FDA chiito pamusoro mwana asati aberekwa.

Zvokuita panguva lactation? Nyanzvi vanokurudzira kuti vakadzi panguva kurapwa kumisa uchiyamwisa.

nemishonga

pamusoro pokushandisa "Flosterona" Chinyorwa rine zvose zvakafanira mashoko pamusoro chipimo chemushonga zvinodhaka kwete chete, asiwo pamusoro wayo nemishonga. nekuomarara dzavo uye kakawanda kubatsirwa zvakananga uwandu medicament kuparadzwa, uye nguva kugamuchirwa. Somugumisiro "Flosterona" anogona glucocorticoid kushanda. Chero zvazvingava, zviri anoonekwa somunhu divi maturo.

systemic migumisiro

Kazhinji varwere kana uchishandisa "Flosterona" vasangana nemishonga kwakadai sokunetseka, kuvhiringidzika, nekuvhiri- ngika, nokusagadzikana, aone zvinhu zvisipo, euphoria, paranoia, kuora mwoyo, pseudotumor cerebellum. Paiva zviitiko apo murwere paaiita mushonga aigona kunzwa nemusoro, vertigo, dzungu. Vanotsvakurudza vakaona kuti somugumisiro kunokwanisa kuva subcapsular cataract uye intraocular kumanikidzwa kuwedzera, iyo pakupedzisira inotungamirira yemaziso, optic kukuvara tsinga uye exophthalmos steroid.

Uyewo, systemic migumisiro zvinochengetwa pamusoro chikamu hematopoiesis uye kumwoyo. Saka, "Flosteron" izvo chikumbiro anofanira akabvumirana chiremba, anogona kukonzera ECG anoshandura runowanzoitika hypokalemia, thrombosis, hypercoagulability, myocardial dystrophy, chirwere chemwoyo pavarwere vafanorongerwa, uye BP.

matanho okudzivirira

Varwere zvimwe navanachiremba ezvinhu chisingaperi, izvo zvinoita kuti pave chirwere chepfungwa, pangava kutyorwa zano rakadaro. Izvi zvinoshandawo kune zviitiko apo chipimo chemushonga "Flosterona" mukuru kwazvo. Muchiitiko chino, zvingaratidza kuitika pashure pemavhiki kana pakarepo mushure mekugamuchira zvinodhaka.

Chenjerera 'Flosteron "zvinofanira kutorwa vaya vanotambura cheshuga, herpes simplex pamusoro cornea, chinonzi systemic lupus erythematosus. Mukupera nyaya kunowedzera mukana avascular necrosis. Uyewo, kuti mushonga vanofanira kubatwa nokungwarira kuti vanhu vakura sezvo kazhinji kuva neBP uye osteoporosis. Izvi zvinoshandawo kune naka pabonde ari postmenopausal munguva.

Action "Flosterona" yakakura mune chiropa cirrhosis uye hypothyroidism. Uyewo, chirwere kwokubatsira zvinodhaka pane mukana adrenal insufficiency. Fani iyi inogona kuchengetwa kwemwedzi inoverengeka yacho wava "Flosterona".

At kurapa zvakakwana refu-refu zvimwe zvirwere muvana zvakafanira kuongorora simba okukura kwavo uye kukura. Nokuti chinangwa ichi isu kuti nguva nenguva ophthalmologic kuongorora. Izvi zvinobvumira iwe kuziva tsanga, yemaziso nezvimwe zvirwere. Nyanzvi vanokurudzira kuti kuramba kuongorora mabasa ari hypothalamic-pituitary-adrenal hurongwa, uyewo kuongorora kuvapo fecal zvemashiripiti ropa, uwandu shuga iri weti uye ropa, serum electrolytes. Izvi zvinoshandawo kwete chete kune vanhu vane chirwere cheshuga. Kana "Flosteron" rinoshandiswa zvakanyatsorongwa, zvinokosha kuongorora eeg.

Somushonga chigadzirwa aida kurapa zvirwere ganda hakufaniri pachena kuti mucosal uyewo mumaziso. Panguva mushonga "Flosteronom" anofanira kudziviswa kubaya uye majekiseni anodzivirira.

How kuverenga chipimo chemushonga zvinodhaka

Kana murwere kunoda systemic kushandisa glucocorticosteroids, kuti "Flosteron" (kurira kwepfuti), mashoko anokurudzira kuti iwe kupinda chete intramuscularly. Kune dzimwe nzira yokushandisa Pfungwa iyi. Mune zvimwe zviitiko intradermal, intra-articular uye periarticular yaitonga.

Kana chipimo chemushonga zvinodhaka, izvozvo anovamba chiremba. Huwandu zvinodhaka hakubvi chete pamusoro kwokuomerwa chirwere, asi murwere zera, chiremba apindure zvakakodzera kurapa uye zvimwe zvinoratidza. Kazhinji, vanachiremba chigaro pfupi nguva kugamuchirwa "Flosterona" uye shoma chipimo chemushonga. Kakawanda murwere pakutanga chinotarisirwa chete 1 kana 2 milliliters zvinodhaka paavhareji chete dose.

Zvavakabvumirana chipimo chemushonga kuti intravenous Kutarisirwa

A mhinduro aizomupa inowanzopiwa ushandiswe aizomupa kana bolus kunonoka. In chete dose ichi pakati 4 uye 8 milligrams, izvo unoenderana 1 uye 2 milliliters azvaitwa. Kana zvakakodzera, yokugadziridza uwandu zvinodhaka. The chipimo chemushonga vangava dzimwe nguva kusvika 20 milligrams, uye kutsigira - kubva 2 kusvika 4 milligrams. Kana medicament inowanzopiwa rakasanganiswa dextrose kana 0,9% yavaibvisa chloride mhinduro. Gadzirira pakarepo asati zvinodhaka kutarisira. Kana mhinduro asina zvimwe zvinangwa, saka inogona kuchengetwa kwamazuva vari inotonhorera nzvimbo, kunyanya mu firiji.

The chipimo chemushonga nokuti intramuscular Kutarisirwa

Mirayiridzo kushandiswa "Flosterona" haabvumiri kuziva uwandu husingakuvadzi pachavo. Naizvozvo, achitora mushonga vanofanira kukurukura nachiremba wako. Kana mushonga unoshandiswa sechinhu intramuscular jekiseni, nyanzvi dzinokurudzira kuti nezveupenyu zvikuru. Kazhinji panguva chakakomba zvirwere, semuenzaniso, chinzvimbo asthmaticus, kana UYU, chiremba prescribes kutanga dose of 4 kusvika 8 milligrams. Kana murwere - mwana ane makore anobva mumwe makore mashanu, pane rinoshandiswa zvakasiyana chipimo chemushonga. Muchiitiko chino, basa kwokutanga jekiseni iri uwandu 2 milligrams. Panyaya iyi gadziriro inogona rakasanganiswa. Vana 6 kusvika 12 makore pakutanga kugadza 4 milligrams.

"Flosteron" (kwepfuti) murayiridzo mvumo kushandisirwa vachangoberekwa pamwe rokusamhanyira pakuberekwa. Izvi zvinoitwa nokuda kudzivirira hyaline Kamudzira chirwere. Kazhinji mushonga chinotarisirwa asati aberekwa, maawa 48-72. At chipimo chemushonga ichi hazvifaniri kupfuudza 8 MG. The jekiseni chechipiri rinoitwa zuva pashure.

Chipimo chemushonga uye periarticular chikumbiro vnutrivertikulyarnom

Panyaya iyi, nokuti pakurapa vakawanda zvikuru majoini jekiseni kubva 4 kusvika 8 milligrams "Flosterona" kuti svikiro majoini dzakadai chiningoningo kana kugokora, - kubva 2 kusvika 4, nokuti guru majoini dzakadai fudzi, neketani uye ibvi - kusvika 4, uye nokuda diki - kubva 1 kusvika 2. Kana marapirwo rinoitwa ganda zvirwere, chete chipimo chemushonga inofanira kuva pamusoro 0.2 milliliters muzana mativi sendimita. Izvi zvinoda chinotarisirwa asingapfuuri 4 milligrams pavhiki.

The chipimo chemushonga zvinodhaka zviri munharaunda infiltration

With nzira iyi kushandiswa nyanzvi dzinokurudzira kushandisa zvinotevera dosages zvinodhaka zvinoti: periarticular kuzvimba peritendinite, fibrosis uye myositis - kubva 2 kusvika 4 milligrams pana tendinitis - kusvika 2, pamwe synovitis uye synovial chikofu, uye bursitis - 1 fung 2.

Zvokungwarira

zvinodhaka "Flosteron" inofanira kushandiswa nokungwarira zvikuru. Mirayiridzo kushandiswa majekiseni mu ampoules kana mahwendefa zano kushandisa zvakasimba maererano nechinangwa chipimo chemushonga. Sezvo jekiseni zvinodhaka izvi zvikuru inorwadza, zvinonzi akabvumidzwa sanganisa mushonga ari mhinduro pamusoro zvakaenzana kukamura uchishandisa akambozvishandisa kuuraya utachiona. Nokuti "lidocaine" ichi akanaka kana "procaine hydrochloride." Saka vakavhengana mhinduro vanofanira kuva sirinji, kwete ampoule.

Munguva pokushandisa zvinodhaka "Flosteron" zvakakodzera kudzora apore. Kuti aite kudaro, bata nguva miedzo ropa, glycosuria uye glycemia. Inofanira airamba achiongorora zviri yeplasma electrolytes.

Kana mushonga unoshandiswa tibhii kurapwa, septic ezvinhu uye intercurrent zvirwere, zvakakodzera kuti tiite zvose inorwisa mabhakitiriya.

Vana vari kugara vachionana huku kurwara pox uye gwirikwiti, nokuti nguva kurapwa wamuchapa zvakananga Siemens. Pregnant vakadzi vaya vari kufura kwako mwana mukaka, kugadza "Flosteron" chete kufungisisa anokarirwa zvabuda, uyewo Migumisiro pamusoro azvarwa.

Vana ivavo vari munguva yokukura, kazhinji ushandiswe mishonga izvi chete nezvikonzero zvoutano. In nzira iyi "Flosterona" mune iyi yaifanira pasi kutarisira kupinda nyanzvi. Zvinofanira kurangarirwa kuti varwere hyperthyroidism kunowedzera Clearance kuti corticosteroids uye varwere hypothyroidism nekusiyana, kunoderedza.

Which chinodhaka akanakisisa

Chii kuti vanosarudza: "Flosteron" kana "Diprospan"? Kutaura zvazviri, mishonga ava analogues. Formulations izvi vane chimwe chete chikuru zvinoriumba, uye ivo siyana yokuvirisa. Kazhinji mushonga imwe chisimbwa, apo wechipiri vakakwana.

Hazvina zvakafanira kuchinja mushonga chete kana kutsiva "Flosterona" analogues isingadhuri kungaita utano murwere. Zvinofanira kurangarirwa kuti "Diprospan" ane yepamusoro bioavailability. Naizvozvo, nyanzvi dzinokurudzira kuti kurishandisa panjodzi.

analogs

"Flosteron" dzinogona kuwanikwa kwete Pharmacies zvose. Analogs angapedza dambudziko. In okuzora akasunungura mari "Akiderm", "Beloderm". Ivai dzomuzana mamwe marudzi, ndiyo "Betamethasone valerate," "Betamethasone Sodium Phosphate" "Betamethasone", "Betazon", "Beloderm Express", "Betnoveyt", "Betliben", "Diprospan", "Celestoderm-In" "Tselederm", "Kuterid", "Tseleston" uye vamwe. Replacement zvinodhaka zvinogona kuitwa chete pashure zano nyanzvi, akagadza "Flosteron". Analogue, sezvinoita mutemo, kuwanika chete mushonga.