Hormone estradiol: inowanzova vakadzi. Estradiol: chimiro panguva yekuzvitakura

Muviri wemunhu inzira yakaoma, kushanda kwayo kunokonzerwa nemahomoni. Izvi zvipenyu zvinoshandiswa zvipenyu zvinokonzerwa nemasero ezvinyorwa zve endocrine. Vanopinda muropa uye vanokanganisa zvirongwa zvemagetsi uye mabasa ehumukati. Kushaya kwezvikamu izvi zvinogona kutungamirira mukuvhiringidzwa kwebasa rehurongwa hwakasiyana-siyana hwemuviri. Iro sex hormone estradiol inonzi inonyanya kukosha pakuberekera basa . Zvinowanzoitwa nevakadzi veizvi hazvirevi chete kubereka kwevana vane utano, asiwo hunoita maitiro avo.

Chii chinonzi estradiol?

Iyi ndeimwe yemakoroni ekurara anokosha zvikuru , ari eboka reestrogen. Pasi pemutungamiri wake, yose yehutano yehutano uye nhengo dzomukati dzinotarisira kubereka zvinoumbwa kune vakadzi. Mukuwedzera, chinhu ichi chinoshandiswa chinokonzera rutivi rwakatenderera rwechimiro muhutano hwakanaka, mazamu kukura, unotarisira kuiswa kwemafuta mashoma pamimba nemahudyu. Iyo hormone inokanganisa hutano hwekuita zvepabonde uye hutano hwevakadzi, inotungamirira kumwedzi.

Ndezvipi zvinhu zvinodaro

Iyo hormonone isradiol muvakadzi inokwanisa kuwedzerwa kubuda kwechiropa mukati mechibereko, zvinoita kuti pave nemamiriro ezvinhu emidziyo. Zvinhu zvinoshanda zvine:

• Anabolic action.
• Inokurumidza kufungisisa kweii.
• Inosimbisa kushandiswa kwemagetsi mumapfupa emapfupa.
• Inochengetedza mvura uye sodium mumuviri.
• Inoderedza cholesterol.
• Inowedzera ropa clotting.

Estradiol inokurudzira kusunungurwa kwevana vezvematongerwo enyika, izvo zvinoderedza kusagadzikana uye kunodzivirira kutya kunetseka. Yakanaka kwazvo ganda, kusagadzikana, kupenya mumaziso, kushingaira uye kushingaira, kutsungirira mumuviri - zvose izvi zviratidzo zvinopa chimiro chemaitiro eestradiol muropa. Inonyanya kukoshesa yehomoni inowanikwa pakati pemaminitsi gumi nemashanu, uye kusunungurwa kuduku kunowanikwa kubva maawa makumi maviri nemaviri kusvika maawa maviri.

Hemoni iri mumukadzikadzi

Mafungiro eesradiol muropa anogona kuchinja zvichienderana nehutano hwemukadzi uye panguva yose yekuenda kumwedzi. Mumuviri wemukadzi ane utano, hutachiona hwepabonde hunofanira kuderedzwa munguva ye follicular phase yekufamba. Anenge mazuva matatu kusvika maviri vasati vakura muhomoni yepituitary (LH), uwandu hweedradiol hunotanga kubuda, iyo yakawanda inokura zvakasimba uye inopera kusvika maawa imwe chete pamberi peHH peak.

Kwemazuva mashomanana mushure mokufungidzirwa kukuru kwehomoni, lenderedzero ye-estradiol inotanga kudonha zvakanyanya, uye zvakare inowedzera zvishoma nezvishoma. Inozadzisa huwandu hunotevera hunotevera musi wegumi nemashanu mushure mekuvhara. Asi kana kuberekwa kusina kuitika, uwandu hwehutachiona hunotanga kuderera uye hunosvika pachidimbu chinodiwa.

Zviratidzo zvebazi

Zvakakosha kuti musikana mumwe nomumwe aite zvidzidzo zvenguva dzemazinga emahomoni makuru. Kubuda kwezvirwere zvakawanda, kukanganisa kwemukati nhengo nekushanda kusina kunaka kwehutano hwekubereka - matambudziko ose aya anogona kukonzera kana kukura kwehomoni isradiol. Zvinowanzoitika kune vakadzi vasingabereki:

• The follicular phase - the indices inobva 57 kusvika 227 pmol / L mu plasma yeropa.
• Icho chinyorwa chekutanga chinosvika 127 kusvika ku 476 pmol / l.
• Chikamu chechikwata chinowanzobva kune 77 kusvika 227 pmol / l.

Izvo zvinofanira kuonekwa kuti kuvakadzi vane makore (pamwe nekuenda kumwedzi), aya mazinga akaderera zvikuru.

Iyo hormone huru yekuzvitakura

Sezvo vanachiremba vanoti, nechechi yakaderera yeestradiol hazvibviri kubereka mwana. Mushure mokunge, panguva iyi iyo hormone inofanira kunge iri mumuviri muhuwandu hwepamusoro: iyo yakagadzirika yakagadzika yeparcenta inobva pane iyo, iyo inokurudzira kukura nekukura kwechibereko, inowanzoisa kupararira kweropa mumitambo yepelvica. Mukuwedzera, iye ndiye anokonzera kuvhara ropa kwemazuva ose panguva yekuberekwa, kupa hutengo hushoma hwekubuda ropa. Asi zviyero zvakaderera zvezvinhu izvi zvinokonzerwa nehupenyu zvinogona kutungamirira pakuparara, kunyanya munguva yekutanga. Saka, hormone estradiol - inowanzoita pamuviri ndeyokuti:

• 3-6 mavhiki - 0.5-4.0.
• 7-8 - 4.0-7.5.
• 9-10 - 7.5-8.5.
• 11-12 - 8,5-10,9.
• 13-14 - 10.5-12.0.
• 15-16 - 12.0-21.5.
• 17-18 - 21.5-29.0.
• 19-20 - 29.0-37.0.
• 21-22 kusvika 37.0-38.0.
• 23-24 - 38.0-42.0.
• 25-26 - 42.0-45.0.
• 27-28 - 45.0-50.0.
• 29-30 - 50.0-52.0.
• 31-32-52.0-55.0.
• 33-34-55.0-57.2.
• 35-36-57.5-59.0.
• 37-38-59.0-61.0.
• 39-41-61.0-66.0.

Vanachiremba vanokurudzira nguva dzose kutarisa huwandu hwehomoni munguva yese yekuzvitakura.

Nzira yekupedza nayo muedzo zvakakodzera

Sezvo vanachiremba vanoti, yechipiri inonyanya kukosha yeestrogen yeboka revakadzi mune chinzvimbo ndiyo hormone estradiol. Kuve nekuita pamuviri wezvinhu izvi kunofanira kusimbiswa pasi pemitemo inotevera:

• Kazhinji manzwiro emuviri - kuongororwa hakubvumirwi munharaunda yekunyanyisa kunetseka kana kuwedzerwa kuwedzerwa.
• Iwe haugoni kunwa doro uye kusvuta.
• Rimwe zuva usati wadzidza, usabvisa kuita zvepabonde uye zvepabonde.
• Kuongororwa kunoitwa pane isina chinhu mudumbu, mangwanani uye masikati asati asvika.

Kucherechedza mitemo iyi, unogona kuwana mhinduro chaiyo yekuongorora, asi kana iwe usina kuzadzisa zvinoda kana kutora chero mishonga, unoda kuzivisa chiremba pamusoro payo.

Chii chinogadzirisa uwandu hwehomoni muropa

Zvakakosha kuziva kuti nei chiito chinoshanda chinowedzera kuiswa muropa. Zviratidzo izvi zvinoratidza kuvapo kwezvinhu zvinotevera:

• Kushivirira kwe follicle.
• Nzvimbo dziri mumapapiro omumiririro ekupedzisira.
• Zvipembenene zvakasiyana-siyana zveivhai.
• Kurwisa kwechiropa.
• Kutora zvinodhaka phenytoin, ketoconazole, mifepristone, nafarelin, estrogens.

Estradiol yakaderera pane yakasarudzwa muvakadzi inogona kuva nekuda kwezvikonzero zvinotevera:

• Hypogonadism.
• Pituitary Nanism.
• Hyperprolactinemia.
• Kusakwanisa kwechikwata chekateti.
• Viral Syndrome.
• Syndrome Shereshevsky-Turner.
• Kurwara kusingaperi mune nhengo dzomukati dzomukati.
• Njodzi yekuparara.
• Kusvuta kwevakadzi vane pamuviri.

Mune zvimwe zviitiko, kukanganiswa kwehomoni kunowira nekuda kwekuwedzera kwekuita muviri, kurasikirwa kwakakomba, pasina mafuta muzvokudya, zvinodhaka. Zviratidzo zvekuderera kweeradirosi zvinosanganisira ganda rakaoma, kusagadzikana kwepanguva yekuenda kumwedzi kana kusavapo kwakakwana, kutora nguva refu, kutapudza mazamu. Saka, zvakakosha kutarisa hormone estradiol panguva yekuronga pamuviri. Zvinowanzoitwa nevakadzi veizvi zvinopa kwete kungoita mabudiro akabudirira, asiwo zvakanyanya kuwedzera mukana wekuita gumbo nekubudirira mubereki mumai anouya.

Mishonga

Kana, semugumisiro wekubvunzurudza, uwandu hwakaderedzwa hwewesradiol hunogadzirwa, chiremba anogona kupa mishonga ine chinhu ichi. Havangobatsiri chete kugadzirisa kurara kwemazuva ose, asi vanoratidzwawo mu polycystic ovaries, vaginitis, infertility, nehutera hwemadzitateguru, nekunonoka kunonoka, pakudzivisa maitiro ekuberekwa mushure mekuberekwa, nehutachiona hwehutachiona. Mishonga yakadaro inobudiswa nenzira dzakasiyana-siyana: mahwendefa, transdermal gels, zvinogadziriswa mumagetsi, mapiritsi emaspirin, zvirongwa zvekurapa zvirwere. Yeuka, chiremba anoenda chete ndiye anogona kupa chirwere chakakwana! Zvichienderana neunhu humwe hunhu hwekushandisa kwemuviri:

• Mapiritsi "Estrofem."
• Proginova gel.
• Solution for injection "Estraderm TTS 25".
• Gel "Estradiol".

Pashure pokunyatsoongorora gynecological, chirwere chinorayirwa, chinotora nguva yakareba kwenguva refu. Kurapa kwakadaro kunoita kuti iwe uwedzere hormone estradiol mumuviri. Chimiro chevakadzi pairi chinhu chinonyanya kukoshesa kushandiswa kwemaitiro ekuberekwa uye kutanga kwehutumbi.