APTT akamutsa: Ko uyu kuitika? Wedzerai APTT panguva pamuviri

APTT (kusashanda haasaruri thromboplastin nguva) - iri rinokosha chaizvo chokukomborerwa pakugwamba ropa, izvo zvinoita kuti kuona ngozi ropa clots kana panowanikwa ropa. Nemazvo dzinoongorora basa coagulation ezvinhu, unogona kusarudza kuti yakanyanya chirwere chacho, uye sarudza kurapwa nemazvo. Ngatitaurei nezvazvo.

Sei APTT bvunzo?

Inoongorora pamusoro mwero kweropa kunobatsira kuziva systemic abnormalities kuti kazhinji anoratidza kuti pane kutyorwa quantitative uye Qualitative zviratidzi rimwe ropa.

kuongorora zvakadaro rinoitwa ari muenzaniso chaiwo. Chokutanga, mashoko kuti aongororwe, vari kuwedzera chubhu yaichengeta anticoagulant nokusungwa calcium ions, nokuda izvo ropa haaiti clot. Chinozoiswa ne centrifugation vaparadzane plasma kubva maplatelet nezvimwe zvinhu. Zvadaro, muedzo chubhu Wakawedzerwa phospholipids, karusiyamu chloride uye activator. Kutanga kuongorora iyo ropa clot aumbwa.

Phospholipids Activate ari extrinsic gwara pamusoro coagulation, uye calcium yakawanda chloride chinhu fuma inokosha nedanho coagulation. Kwakadaro kuongorora haanyatsonzwisisi kuyera chirongwa thrombus inotungamirwa, asi chinobatsira kuziva abnormalities ari zvazvingava, kuti ipapo tsvaka zvinokonzera chiitiko ichi.

Dzimwe zvinoitika kuti APTT akawedzera kana shoma. Izvi zvinoratidza aripo matambudziko mumuviri.

wokuyera

The chakarurama kunoyerwa mumasekonzi uye anogona siyana nokuda simba, zera murwere uye kurapwa. APTT Normal akura munhu kubva 28 kusvika 40 seconds. Vachangoberekwa, nhamba iyi yakakwirira kuti 1-3 seconds.

Yakakwirira ropa aPTT kunokwanisa kuonekwa kana chero pakugwamba chinhu ipfupi kana kwakawedzera neinopfuura 30%. Akaderedza zvazvingava kazhinji chinoratidza hypercoagulability.

Kutsunga APTT mune vakuru nevana ndakaiswa kuona chikonzero murombo ropa clots, uyewo kuti vaongorore kubudirira kurapwa pamwe anticoagulants.

Zvikonzero kuwedzera APTT

Vazhinji kwazvo vakatsamwa kana vanoona kuti APTT akawedzera. Zvinorevei? Izvi zvinoitika kana paine mukana ropa. Zvikonzero angava:

1. Kushomeka yakawanda vhitamini K pamuviri. Izvi anotaura zvinetso zvomudumbu ino, nekuti vhitamini ichi chinosimudzira kwetunhu intestinal mabhakitiriya. Zvinoitawo kunokosha kuti chakaipa nokushanda kwenhengo zvose pakugwamba zvinhu. kushaikwa kwayo kunoitika nokuda dysbiosis, ine hasha zvokudya, zvichiguma mabatiro-refu pamwe nemishonga.
2. Genetic abnormalities kuti chokuita kutyora Qualitative uye quantitative parameters ropa. Muchiitiko chino, indekisi APTT zvikurusa.
3. Postpartum ropa, rikwanise neleukemia, DIC.
4. Hemophilia mhando A, B, C.
5. Kuvapo antibodies muropa kuzorwa Kumbofungatira zvinhu uye lupus anticoagulant.
6. Usava kugadzirira pachisara netsaona ingress kuti heparin iri mharidzo.

Yakawedzera APTT, mwana anogona kunge nokuda kwezvikonzero izvi.

APTT panguva pamuviri

Panguva pamuviri, asi kusashanda thromboplastin nguva haasaruri iri kutanga kuchinja. Kana mwero kuti avhareji munhu ari pakati 28 kusvika 40 masekonzi, vakadzi vane pamuviri zviri 17-20 seconds. Izvi zvinoreva kuti ipfupi. Kuchinja kwakadaro kutsamwisa zvinhu zvinotevera:

• Iyi yakaoma mumuviri mumwe mukadzi, chimwezve utero-placental kutenderera. Placenta rine muzvizhinji rwengarava. Kunyange kana inoitika chiduku yokuzviparadzanisa, kurasikirwa ropa kunogona kuva kunokosha. Kazhinji yokuzviparadzanisa kunoitika nokuda vawedzere uterine inzwi.
• Panguva pakagadzwa mukadzi kazhinji anorasikirwa kusvika 400 ml ropa. Izvi zvinoitika nokukurumidza uye coagulation gadziriro vazvigadzirire zvakadaro kwazvo nokurasikirwa neropa, saka clots vari kutanga kuumbwa nokukurumidza kudzivisa kumwe kurasikirwa neropa.

Sei APTT kwakasimudzirwa ari pamuviri?

APTT ichiwedzerwa kana pakugwamba nguva yava mumasekonzi anopfuura 40. Izvi zvinoderedza mano ropa clots kuti aumbe, zvichiguma nengozi yakakwirira kurasikirwa neropa.

Kazhinji APTT vakawedzera kana mukadzi ane mimba iri kutora mishonga, heparin, asipurini uye zvinodhaka thrombolytic. Zvisati aedzwe, inofanira kuzivisa chiremba wavo.

Kuwedzera APTT kunoratidza vasanyanye ropa anogona clot, uye rinowanikwa mune zvinotevera pathological ezvinhu:

• Chiropa chirwere vainge vakamonera akaratidza hepatic kukundikana, kusanganisira uye cirrhosis. Muchiitiko ichi pane kutyora kwetunhu pakugwamba zvinhu zviri muropa.
• Kushaikwa vhitamini ari K, rinowanika pamusoro yaitwa dysbiosis ari dumbu, uyewo nokuda zvokudya kukodzera.
• Neleukemia.
• Hemophilia mhando A, B, C. Iri nhaka chirwere dzinoratidzwa vachiberekwa kushayiwa pakugwamba zvinhu, kazhinji zvichiguma kwatangwa ropa kuitika.
• chirwere Von Willebrand vake.

mhedziso

Analysis pamusoro APTT hazvo kunze pamberi kukasaitwa kushanda kuti tione sei kutsanyisa ropa anogona clot. Kuwedzera kana kudzikisa kubva ndozvakajairwa inoratidza pathologies siyana. Kuti tidzivise ngozi ropa, kurapa maererano.