Analysis musi PTI: zvaigara. PTI: Muzvarirwo vakadzi

Prothrombin indekisi (PTI) - chimwe chezvinhu zvinokosha rabhoritari nemiedzo, iyo inechirevo mamiriro coagulation hurongwa. Chinotaurwa kuva chikamu. A-siyana ezvinhu vakanzi ongororo PTI. Norma utano vanhu 95-105%.

Kweropa rinoitwa zviviri nzvimbo - mukati uye extrinsic anotenderera. Kukosha IPT anoratidza chaizvo extrinsic gwara pamusoro coagulation.

Chii prothrombin?

Paumbwe clots ropa uye clots kuchiitika pasi pokudzora imwe mapuroteni - thrombin, riri pasi pokudzora zvimwe pezvakaitwa nokukanganisika kutendeuka kubva prothrombin. Saka, puroteni wechipiri prothrombin pakugwamba chikonzero. Zvinonzi anogadzirwa pamwe kutora chikamu vhitamini K ari chiropa.

Prothrombin indekisi (nokuti SWIR) kuziva basa prothrombin. bvunzo ichi rinowanikwa ave chikamu zviratidzi ropa zvomurwere yeplasma kuti kudzora waungapa. Nokuti kudzora coagulation gadziriro iri basa bvunzo ropa PTI. Ndozvakajairwa mumarabhoritari dzakasiyana dzingasiyana zvishoma, asi misiyano izvi hazvisi chinokosha. Ivo kuvimba makemikari zvokushandiswa murabhoritari. Under zvimwe zvinhu, zvakadai varicose mutsinga, yomwoyo kana pashure akavhiyiwa pamwoyo prices varwere ndakatsunga nachiremba, sezvo Muzviitiko izvi zvakafanira kuti vabudirire ropa anticoagulation (achidzikisa pakugwamba kwayo). Izvi zvinoitwa nokuda kudzivirira thrombosis.

Ndiani akagadzwa Kuongororwa musi PTI?

Kazhinji kudzidza mwero IPT vakadzi kufanana nevarume. Nhamba iyi Kuchinja chete panguva pamuviri, uye pane zvikonzero zvakawanda, izvo tichakurukura gare gare. Mune zvimwe zviitiko, ropa kemisitiri akagadza PTI? Ndozvakajairwa wetsvakurudzo Somuenzaniso, kana achitora anticoagulants zvingava yakaderera pane kaviri. Varwere kushandisa zvinodhaka izvi zvinofanira kuongororwa nguva uye INR PTI. Research musi PTI hazvo kuitwa mumamiriro anotevera:

• Pamberi chero kushandiswa.
• Vanhu kugamuchira mushonga anticoagulant kudzivirira ropa.
• Women panguva yepamuviri.
• Vanhu kutambura zvirwere coagulation ezvinhu akadai varicose mutsinga.
• In autoimmune zvirwere.
• In atherosclerosis uye mwoyo chirwere.
• Kana chiropa pathologies, akadai cirrhosis.
• At kushayiwa vhitamini K.
• In antiphospholipid syndrome.
• Nokuti achivhara miedzo coagulation.

Panguva pamuviri, iva nechokwadi kuti zvakaitika bvunzo kuti PTI. Ndozvakajairwa vakadzi panguva pamuviri zviri zvishoma kupfuura kuti vamwe vanhu utano. Izvi imhaka kuchinja kwemakemikari omuviri siyana uye kwaita mamwe utero-placental kutenderera.

IPT panguva pamuviri: ndozvakajairwa

Panguva pamuviri, vakadzi vose vanofanira kugadza kudzidza coagulation. Zvinosanganisira:

1. PTI (prothrombin indekisi).
2. INR (International normalized reshiyo).
3. APTT (kusashanda haasaruri thromboplastin nguva).
4. Fibrinogen.

parameters zvose izvi zvichikosha chaizvo. Saka, kuwedzera IPT okupedzisira mumatanho pamuviri kusvika 150% kana yakakwirira zvingaratidza kuva mukana placental abruption. Uye vasanyanye chokukomborerwa ichi pamberi wakurukura pazasi 80% pane njodzi ropa pakusununguka kana ari postpartum nguva. Saka zviri kunyanya kukosha kuongorora coagulation hurongwa pakupera pamuviri. Kuti aite izvi, rasai PTI bvunzo. Ndozvakajairwa pamusoro indekisi ichi panguva pamuviri anoda kubva 90 kusvika 120%.

Ko kuwedzera PB?

Saka, takaona kuti thickening ropa zvinowedzera kukosha IPT. Ndozvakajairwa pamusoro indekisi izvi utano vanhu anoda kubva 95 kusvika 105%. Kuwedzera prothrombin indekisi zvingaratidza ngozi dzichiri zvirwere zvakadai:

• Myocardial infarction.
• Thromboembolism.
• Polycythemia.
• Oncological zvirwere.
• Yokuzviparadzanisa of placenta vakadzi vane pamuviri.

Ko munhu pasi azvipire PTI?

Muzviitiko kugamuchira anticoagulants PTI pamwero kunogona pasi 45-40%. With nokutyisidzirwa ropa clots dose zvinodhaka izvi kudzora chiremba. Pashure kuwedzera kana kuderedza dose kunodiwa kurega ongororo IPT. The zvazvingava varwere idzi pakutsvaga kupinda chiremba. Kana prothrombin indekisi yakaderera varwere kugamuchira anticoagulants, ichi zvingaratidza Somuenzaniso, vhitamini K kushaikwa, zvikuru chiropa chirwere kana nemudumbu seboka, uye vakadzi vane pamuviri asati aberekwa - pamusoro mukana ropa panguva basa.

Chii INR?

mufananidzo uyu ndiye chiyereso Pakusarudza kweropa. INR ikasakendenga basa nedzimwe mapuroteni ropa, zvinova pakugwamba zvinokonzera. mapuroteni akadai anogadzirwa chiropa kwaibatanidza vhitamini K. Ava coagulation zvinoita sei kuti mishonga - anticoagulants, semuenzaniso, "Dabigatran" "warfarin" kana zvavo analogs. In Muchiitiko ichi, hypocoagulation, i.e. Kweropa iri nomumugwagwa kwaitora nguva zvikuru. Vamwe varwere, zvinokosha, vakawanda vanomanikidzwa kutora anticoagulants upenyu.

Analysis PTI ropa. INR: wokuyera

In coagulogram, kunze kuongorora IPT, uye zvimwe zvikonzero zvinokosha. Kana raitongwa varwere anticoagulants IPT ungaderedza. Asi kuongorora mwero IPT neimwe murabhoritari dzingasiyana zvishoma, saka wakatangwa kwezvipimo bvunzo - INR. Doctors kurishandisa kudzora ropa coagulation hurongwa kana achitora anticoagulants varwere. Saka, muna muzviitiko izvi INR riri basa pamwe zviratidzo zvakadai muedzo kune PTI ropa. Normal INR vanhu hwakanaka 0,8 kusvika 1,2. Kana muchigamuchira wakaderedzwa anticoagulant pakugwamba kunoitika hypocoagulation uye INR anogona ngazviwedzerwe 2-3 nguva ndozvakajairwa, zvakadai kuvhiya mwoyo kana varicose mutsinga kudzivisa paumbwe thrombi. Kana ropa rinova mukobvu, chakatowedzera coagulability uye maererano INR indekisi kunoderedza.

Hypocoagulation. Mune mamwe mamiriro ezvinhu zvichidikanwa?

Mwero IPT munhu akaidza anoda kubva 95 kusvika 100% uye INR kuti 0,8 kusvika 1,2. Yeuka, mitemo iyi inofanira kuva vanhu zvakakwana hwakanaka. Asi pane zvinhu kana INR zvinokosha kuramba yakakwirira dzemitambo, ukuwo, PTI zviratidzi saka kuva pazasi dzose, kureva, ichava mamiriro anticoagulation. mamiriro kwakadaro kunoitwa kutora anticoagulants. The dose inogona tsunga chete nachiremba. Varwere nguva kugamuchira mishonga yakadaro nguva dzose inofanira bvunzo kuti INR ropa.

• Kana atrial fibrillation INR tsika anofanira kuchengetedzwa vari kuwanda 2.0-3.0.
• Heavy Hurumende - Pe (pulmonary embolism) - kunodawo kuramba INR siyana mukati 2.0-3.0.
• Pashure pokuvhiyiwa mwoyo kunoda anticoagulation, apo panyaya kutsemuka vharafu INR nhamba anofanira kuchengetedzwa nenzira yakakodzera siyana 2.0-3.0, uye mune prosthetic mitral vharafu - pachiyero 2.5-3.5.
• Mune dzimwe kuremara, mwoyo mavharuvhu (mitral kana kutsemuka kuremara), uye kudzivirirwa thromboembolic pamwero indekisi ichi mukati 2.0-3.0.
• In pakurapa venous thrombosis INR nhamba vanofanira anoenderana 2.0-3.0.

Akaroromesawo prices pazasi bvumidzwa muganhu INR kuwedzera dose "Warfarin" uye ayo analogues. Izvi zvinoitwa chete pasi wezvokurapa achitarisirwa uye mumarabhoritari nekuongororwa. Asi kuwedzera anticoagulation (yakawedzera INR) pamusoro bvumidzwa mukoridho kunogona kukanganisa utano varwere. Hazvina ngozi anonyanya siyana kubuda ropa. Vanogona kuva zvemukati (uterine, dumbu kana intracavitary) dzokunze yomuka mukukuvara siyana kana maronda. Kana nhamba sezvarakakwirira INR bvumidzwa mwero akasarudzwa kuti imwe mamiriro, ari dose ose anticoagulants zvinofanira kuderedzwa. Vamwe varwere vane kudzora pachiyero INR upenyu.

Sei bvunzo kuti INR uye IPT ropa?

Ropa riri kudzidza kwakadai aitengesa kurapwa mukamuri. Venous ropa inocherechedzwa bvunzo chubhu ane anticoagulant, basa iri kazhinji yavaibvisa citrate. The reshiyo pakati wakasuduruka ropa uye anticoagulant kuva 9: 1. Kuendeswa yokuenzanisira yakavhenganiswa kunyatsoverenga inverting kuti chubhu kudzivirira clot inotungamirwa. Ropa pakarepo akatumira murabhoritari. Analysis vanofanira kubereka papera pane maawa maviri pashure ropa muunganidzwa. Kukundikana kutevera izvi zvinhu zvinogona kukanganisa kuongorora. Ropa kakawanda akabata mangwanani usina chawadya, asi ongororo iyi inogona kuitwa pane dzimwe nguva achishandisa cito kana zvakakodzera, kureva nokukurumidza.