ALS chirwere: chinokonzera, zviratidzo uye kosi. Chirwere uye vabatwe chinonzi amyotrophic lateral sclerosis

mushonga ano anogara Virtual. Masayendisiti ndinosika Kurapa itsva nehosha adarika. Zvisinei, vanamazvikokota havagoni nhasi zvinopa zvakakwana pakurapa zvirwere zvose. Mumwe chirwere akadaro ALS chirwere. The zvinokonzera chirwere ichi vachiri unexplored, uye uwandu varwere ose gore chete inowedzera. Munyaya ino isu kunyatsotarisisa panguva zvokurwara ichi, ayo chikuru zviratidzo uye nzira kurapwa.

Vhuṱanzi

Chinonzi amyotrophic lateral sclerosis (ALS, Lou Gehrig nehosha) kwakakomba zvokurwara pakati tsinga, panguva iyo munhu anonzi kurasikirwa injini Tutsinga tunofambisa mashoko utwu ari musana uyewo muuropi cortex. Chinhu chirwere uye chirwere chisingarapiki kuti zvishoma nezvishoma kunotungamirira kuti degeneration pakati tsinga. Mumazuva okupedzisira nzendo chirwere munhu anova kuzvibatsira, asi iye akaramba ari pfungwa yakajeka uye utano hwepfungwa.

ALS chirwere, zvinokonzera, uye kuti agumise pathogenesis haina kudzidza, hapana chakasiyana chaizvo chirwere uye kurapwa nzira. Masayendisiti nhasi vanoramba vachishingaira kuongorora izvozvo. Zvino zvinozivikanwa kuti hosha ikabuda kunyanya vanhu vane makore 50 uye kusvikira anenge 70 apfuura, asi pane nyaya uye kwokutanga kukundwa.

kupatsanura

Zvichienderana nzvimbo inokosha zviratidzo chirwere nyanzvi vari zvinotevera chimiro:

1. Lumbosacral chimiro (pane kutyora injini basa repasi maoko nemakumbo).
2. Bulbar chimiro (zvimwe ane pfungwa nuclei, iyo rinobatanidza boka kuoma nechepakati mutambi).
3. Remuromo-thoracal chimiro (chikuru zviratidzo vanoziva Kuchinja gwenya kushanda okumusoro maoko kana makumbo).

Ukuwo, nyanzvi kusiyanisa mhando nhatu ALS chirwere:

1. Mariana chimiro (chikuru zviratidzo kuitika mangwanani zvikuru, pane anononoka weboka chirwere).
2. Classic nguva dziri kure mhando (95% vose nyaya).
3. Family mhando (akasiyana mukupera kuratidzwa uye nenhaka kubatwa).

Sei ipapo ALS chirwere?

The zvinokonzera chirwere ichi, zvinosuruvarisa vachiri havaratidzi kunzwisisa. Masayendisiti ikozvino oga zvinhu zvinoverengeka, pamwe nokuvapo chiri zvichida kutanga rakawedzera kanoverengeka:

• ubikvina mapuroteni mutation;
• muchirwadzisa matanho neurotrophic chinhu;
• kunotouraya vamwe majini;
• yakawedzera vakasununguka kukuru oxidation mumasero neuronal pachavo;
• Kuvapo rwarisa mumiririri;
• vakawedzera basa kunzi excitatory amino acids.

ALS chirwere. zviratidzo

Photo varwere chirwere ichi chinogona kuwanika unyanzvi Directories. Vose zvakabatanidzwa chete nomumwe chinhu - the kwokunze zviratidzo hosha mukupera nezvishoma.

Panyaya chikuru zvekuchipatara zviratidzo chirwere, ivo kwazvo kashoma kukonzera kuchenjerera pamusoro chikamu varwere. Uyezve, varwere zvinogona kazhinji vatsanangure tinyanye kunetseka kana kushayikwa zororo kubva basa nezuva. Zvinotevera zviratidzo hosha, kuitika mukutanga mumatanho:

• tsandanyama simba;
• dysarthria (zvakaoma pakutaura);
• kakawanda kwetsandanyama;
• chiveve uye kuneta maoko nemakumbo;
• chiedza twitching kuti tsandanyama.

zviratidzo zvose izvi zvinofanira pasvika wose uye kuva chikonzero zvivabatsire kune nyanzvi. Zvikasadaro, chirwere ichava mberi, riri kanoverengeka kunowedzera mukana wokuti yematambudziko.

chirwere

ndiye ALS sei? The chirwere, zviratidzo izvo dzave dziri kumusoro, pakutanga rinotanga tsandanyama simba uye chiveve muruoko wamativi. Kana zvokurwara hwapedyo pamwe makumbo, varwere vanogona vanoomerwa achifamba, dzose vanogumburwa.

Kana chirwere pachena pacharo pamwe Kuvhiringidza okumusoro maoko nemakumbo, pane matambudziko pamwe Implementation kupfuura zvokutanga mabasa (buttoning imwe hembe, tsaukirai kiyi zvechizarira).

Sei zvimwe Ungaziva ALS chirwere? Zvinokonzera chirwere muna 25% nyaya akafukidzwa mu maronda ari medulla oblongata. Pakutanga, matambudziko nokutaura uye ipapo pakuparadza. izvi zvose rinobatanidza nezvinetso kutsenga zvokudya. Somugumisiro, vanhu havachaoni kudya zvakanaka uye uremu. Panyaya iyi, varwere vakawanda vanowira mwoyo mamiriro, nokuti chirwere kazhinji asingadi kukanganisa zvishande ushande.

Vamwe varwere vachinetseka Anoumba mashoko uye kunyange zvinoitwa yevasungwa. kutyorwa Minor izvi mhando zvinokonzerwa nokuda murombo kufema usiku. Vanachiremba zvino kuudza murwere pamusoro zvinhu aibuda chirwere, marapirwo, saka kuti aigona mberi kuita chisarudzo nezveramangwana ravo.

Varwere vakawanda kufa kufema kukundikana kana nemabayo. Kazhinji, rufu kunoitika mukati makore mashanu kubvira musi nokusimbisa chirwere.

Diagnostics

Zadzisai pamberi chirwere kunogona chete kuva nyanzvi. Panyaya iyi, chikuru basa kuti akwanise kududzira yaivapo kunotoda mufananidzo neimwe murwere. Zvinokosha differential chirwere kuti ALS chirwere.

1. Electromyography. Nzira Izvi zvinoita kuzosimbisa pamberi fasciculations mukutanga mumatanho vayo kukura. Panguva nzira iyi, imwe nyanzvi inoongorora Kugwina netsandanyama.
2. MRI anozivisa zvemamiriro foci uye kuongorora kushanda huta hurongwa.

Chii chinofanira kubatwa?

Zvinosuruvarisa mushonga nhasi havagoni kupa zvinobudirira kurapa kuzorwa chirwere ichi. Ndingaita sei kukunda ALS chirwere? Treatment zvinofanira zvainanga zvikurukuru pane tava kuderera kosi chirwere. zvinotevera zviyero anoshandiswa zvinangwa izvi:

• chinokosha masaja maoko nemakumbo;
• pakuparwa kukundikana kufema tsandanyama anodomwa neMutungamiriri zvokuimba kufefetedza;
• mune nyaya doldrums rakarumbidza mapiritsi uye antidepressants. Muchiitiko chimwe nechimwe, zvinodhaka ushandiswe nomunhu;
• kurwadza kwemajoini stoped steroidal Anti-anogumbura zvinodhaka ( "Finlepsin");
• Nhasi nyanzvi kupa varwere vose mushonga "Riluzole". Rine nekusimba chiito uye chiri inhibitor yesununguro kunzi glutamic acid. Kana anwa mushonga kunoderedza neuronal kukuvara. Zvisinei, kunyange izvi zvichireva haisi kukwanisa kurapa murwere zvakakwana, chete izvozvo DZEMUNHU DZINODZORA chirwere ALS;
• kuti zviite kufamba murwere uchishandisa chaiwo mano (tsvimbo, macheya) uketani rakazara Kuda kutamba kwemitsipa.

Chokumisa Sero kurapa

Munyika dzakawanda dzokuEurope varwere pamwe ALS nhasi vari kubatwa yavo hunde masero, izvo zvinobatsira kuderedza budiriro chirwere wacho. mhando iyi yokurapa nechinangwa kuvandudza chikuru mashandiro anoita uropi. Masero hunde vari wakasimwa kupinda hunenge nzvimbo, kwakaderedza Tutsinga tunofambisa mashoko utwu kuvandudza pfungwa oxygenation uye zvinoita pakuonekwa midziyo itsva ropa.

Voga pakati hunde masero pachavo uye dzavo transplantation inowanzopiwa ichiitwa imwe outpatient marongero. Mushure kurapwa, murwere achiri 2 mazuva muchipatara, apo vanachiremba akuteerere ezvinhu ake.

Panguva muchitokisi kurapwa raitongwa kupinda CSF kubudikidza lumbar ponji. Kunze muviri havabvumirwi zvichiberekana pachavo, uye reimplantation rinoitwa chete pashure wandei.

Pazvese, yokurapa uku kunogona yekudyidzana kuderedza chirwere ALS. Photo varwere pashure 5-6 mwedzi nzira zvakajeka zvinoratidza nokusatya ichi. Zvakakwana kubvisa hosha hazvingaiti kubatsira. Zvinosuruvarisa zviitiko zvakadai zvakanyorwa, uye kana kurapwa havapi kushanda.

mhedziso

Fungidziro chirwere ndiyo inenge nguva zvisingafadzi.. Kuchiita rwokufamba zvirwere kunotozongoita rinobatanidza ngozi (makore 2-6).

Munyaya ino takataura nezvekuti iri zvokurwara, sezvo ALS. The chirwere, vane zviratidzo sevasingazivi kwenguva refu, haagoni Pari kurapwa kusvikira pakuguma. Masayendisiti munyika yose kuramba vachishingaira kudzidza chirwere ichi, ayo zvinokonzera uye kukura nokukurumidza, vachiedza kuwana zvinobudirira chingamubatsira.