"Zyprexa": mirayiridzo kushandiswa. "Zyprexa": wongororo, analogs uye contraindications

The huta kwevanhu hurongwa ndiwo murayiro pakati yose muviri. Kana uine matambudziko unogona kuchengeta zvarakasiya ari kukura, mumuviri uye mupfungwa, uye mupfungwa. Pari zvino pane akawandisa zvinodhaka kuti anogona kushanda zvishamiso uye kukubatsira kukunda zvirwere zvakawanda. Mumwe wavo - "Zyprexa". Nyaya ichakurukurwa izvi mishonga kudzidziswa Chinyorwa. "Zyprexa" - mushonga kuti kazhinji nachiremba abnormalities munyika tsinga.

Pharmacological ehupfumi zvinodhaka

mushonga uyu ndohwaJehovha boka neuroleptics zvinobudirira pamusoro chakarondedzera zhinji Kanotokonya enyika. Aiitisa zvidzidzo zvakawanda iyo yakawanikwa kuti olanzapine, zvinoshingaira wemafuta zvinodhaka, ane daka kuti kweserotonin, dopamine, uye cholinergic receptors.

Vakawanawo kuti olanzapine akazoita excitability ari mesolimbic dopaminergic Tutsinga tunofambisa mashoko utwu uye ane zvishoma zvainoita striatal Neural makwara kuti vanobatanidzwa munyaya mutemo motokari mabasa.

The kushingaira wemafuta mushonga runogonesa Anti-kufunganya maturo nenguva anxiolytic bvunzo.

Medicine "Zyprexa" anouya nenzira mbiri:

• Muchimiro mapiritsi, film-zvemapuranga.
• Lyophilizate gadziriro mhinduro kuti jekiseni.

Huru achishingaira chinoita mukugadzirwa unotora olanzapine. Ebetsero zvinoriumba ari mahwendefa ndiwo:

• Crospovidone.
• magnesium stearate.
• Lactose monohydrate.
• Cellulose.
• Giproloza.

The Zvinoumba firimu unhani mahwendefa vari chena colorant, zvokudya ingi zvitema, wakisi carnauba uye hypromellose.

Murwiyo munhu lyophilisate kuti mhinduro kuti jekiseni zvinosanganisira, kunze huru vanoshingaira fuma, lactose monohydrate uye tartaric acid.

In chii fomu kugadza mushonga kurapa murwere, chiremba anofanira kusarudza chete.

Zvairatidza kuti kushandiswa kwezvinodhaka

Drug "Zyprexa" rine zvakawanda zvairatidza kuti kushandiswa, kazhinji zviri nezvaro zvinotevera ezvinhu:

• Schizophrenia ari rikwanise chimiro.
• Tsinga zvirwere achiperekedzwa zvinovadadira, aone zvinhu zvisipo, akafunga nyonganyonga.
• Ataurwa ruvengo nokufungirana nokuda huta zvirwere.
• Emotional kana mumagariro kurega.
• Kuvhiringidzika zviratidzo raikura tikafunga schizophrenia.
• Somunhu prophylactic mumiririri kuti schizophrenia zvazvo.
• Dementia.

Hazvina zvakakodzera kugadza pachake mushonga pasina kurangana nyanzvi, kurapa kwakadaro hwakazara zvakakomba.

Scheme zvinodhaka kurapwa

Ko ichi kudzidziswa Chinyorwa? "Zyprexa" riri basa pamavambo Mabatirwo schizophrenia iri shoma chipimo chemushonga. Pakutanga, zvichaita zvakakwana kutora 10 MG zvinodhaka kamwe pazuva. Kubudirira mishonga zvokudya yaunodya asina maturo.

The kuchirapa chipimo chemushonga zvinodhaka anogona dzinosiyana 5 kusvika 20 MG, asi wakaiswa mumwe nomumwe murwere mumwe nomumwe maonero ayo mamiriro. Mushure ose tsvakurudzo, kana murwere inobvumira zvinodhaka dose inogona hwakawedzera, asi chete pasi zvokurapa achitarisirwa.

In pamberi kutambudzwa zvokudarikidza "Zyprexa" piritsi raitongwa mune imwe mari 15 MG kamwe pazuva. Panguva kurapa zvakafanira kuongorora mamiriro murwere uye chipimo chemushonga kugadziriswa sezvo zvakakodzera.

Kana murwere kutambura kubva hepatic kana renal insufficiency, iye ushandiswe mushonga "Zyprexa" 5 MG, kana hurumende romuzvarirwo uye zvinoreva kwazvo akashivirira, kuti dose anogona ngazviwedzerwe zvishoma nezvishoma.

The mushonga inowanzonzi raitongwa varwere kubudikidza jekiseni. Usati waita chinhu jekiseni, unofanira zvakanaka wokuparadza lyophilisate. Kuti aite izvi, zviri chinu yakanyauka muna 2 ml mvura jekiseni. The wakagadzirira mhinduro inofanira kuva akajeka uye vane yero ruvara.

Sei kutora? "Zyprexa", Sezvambotaurwa, riri basa nyanzvi. Naizvozvo, kurapwa zvaiitwa, kana kurapa rinoitwa kumba, zvinofanira kukurukurwa pamwechete chiremba.

Paunogadzirira kuitwa jekiseni arangarirwe:

• "Zyprexa" anogona zvazvichanyungudutswa chena mvura chete.
• Hazvigoni kusanganiswa chete sirinji zvinodhaka uye "Diazepam".
• Remubatanidzwa "Zyprexa" uye "Haloperidol" inotungamirira kwakaderera Zvakaitwa wokutanga zvinodhaka.

Kana chiremba prescribes mushonga "Zyprexa", kuti chipimo chemushonga kuchaenderana zvokuongorora. Somuenzaniso, muna schizophrenia kwokutanga dose ndiyo 10 MG kamwe pazuva. The mushonga anofanira kuzviita chete intramuscularly. Kana waiti murwere ezvinhu, wechipiri uchibaya mishonga anogona kuita, asi kwete maawa vamba pane maviri pashure yokutanga jekiseni.

varwere Older uye kuvapo zvimwe chisingaperi zvirwere zvinodhaka raitongwa ari chipimo chemushonga pamusoro 2.5-5 MG.

Kufungisisa kuti pakatanga "Zyprexa" kungakonzera kuwa BP panguva jekiseni nani kuva nechinzvimbo nhema, kunyanya kana paine pashure jekiseni hope uye dzungu. Zvakakosha kuti nhema, sokuvapo chiremba pashure pokuongororwa haangavi kugadzirisa kushaya rutapudzo BP uye bradycardia.

Zvinofanira akayeuka kuti abolition kuti "Zyprexa" yaifanira zvishoma nezvishoma, sezvo ari parumananzombe kuti zvinodhaka kurega syndrome. Unofanira kugara kukurukura ichi nachiremba wako.

Refu kurapa "Zyprexa" imwe nguva gare gare jekiseni yakatsiviwa mahwendefa ane chipimo chemushonga 5 kusvika 20 MG pazuva. Chiremba kunodiwa muudzame sei mushonga "Zyprexa" refu anofanira kugamuchirwa. Kuti anobata nzira uye chii kurapwa zano, isu akaongororwa, asi hatifaniri kukanganwa pamusoro vasingadiwi migumisiro.

Side Migumisiro zvinodhaka

Zvinenge mishonga zvose nokuda pakurapa tsinga zvirwere chokuita boka, izvo inokurudzirwa asina kutora pasina kubvunza chiremba. Izvi hazvisi zvagara kuti "Zyprexa" nokuti mushonga ane nani kwazvo mazita nemishonga:

• Tsinga anogona kupindura nomusoro uye dzungu, vakawanda simba uye kushaya hope, kukanganwa uye phobias siyana. Chakamira pakunodengenyeka zvine uye tsandanyama kuomarara kunobvirawo. Kazhinji kune tinnitus, kusanzwa, marwadzo mumaziso, kuravira nyonganyonga.
• On chikamu kumwoyo kungava tachycardia, inodonha BP, kuchinja ECG, cyanosis. Analyses anogona kuratidza neutropenia, eosinophilia, leukocytosis, thrombocytopenia. In Muzviitiko zvakaipisisa, zvinogoneka cardiac kusungwa.
• Pane ngozi rhinitis, pharyngitis, laryngitis, chikosoro kwakawedzera. Anogona achiipa asima, hope kufema ane ngozi.
• Pfari kuwedzera kudya kana bulimia, nyota uye kuoma iri nemumuromo mhango.
• Svoto uye kurutsa.
• Exacerbation kuti gastritis uye gastroenteritis.
• Kutyora cheya uye flatulence.
• Metabolic zvirwere zvinogona kuratidza uremu shanduko, kukura cheshuga, shuga pakoma.
• Urinary incontinence, cystitis, uterine fibrosis, amenorrhea uye kuvandudzwa Urinary turakiti zvirwere zvakare zvisingadiwi kuratidzwa ingestion.
• Mirayiridzo Use ( "Zyprexa", sezvatinoona, mumwe mushonga kuti anogona kukonzera zvakasiyana pasingadiwi nemishonga) anoyambira kuti zvinobvira kukura arthritis, bursitis, chinyamunhari chinorwadza iri mhuru tsandanyama uye kurwadziwa mapfupa.
• Skin anogona sei chitarisiko wokunzwa kuoma, dermatitis, urikanwi idzodzo.
• urticaria kunoitika kakawanda.
• Other zvingaratidza kucherechedzwa fivha, chills, dzihwa-kufanana nehurumende.

Kubva ose pamusoro tinogona kugumisa kuti "Zyprexa" nemishonga zvakakomba zvakakwana, saka mushonga chete zano chiremba wacho.

Zviratidzo ovhadhozi

Kana murwere asingadi kuteerera chiremba kurumbidza kuti chipimo chemushonga zvinodhaka, pane ngozi ovhadhozi, iyo kunoratidzwa anotevera zviratidzo:

• Tachycardia.
• Kunwisa kushatirwa uye utsinye.
• Speech nyonganyonga.
• Havachanyatsogoni kuziva.
• Nokugwinha.
• Neuroleptic syndrome.
• Chinovhiringidza pakati mashandiro afemeruke.
• Akasvetuka BP.
• Arrhythmia.
• In Muzviitiko zvakaipisisa, cardiac kusungwa uye kufema.

At chiratidzo ovhadhozi rokutanga zvakafanira kugeza kunze mudumbu, tora nemarasha. Symptomatic kurapwa rinoitwa maererano zvekuchipatara kuratidzwa, uye kuramba kuongorora mashandiro zvinokosha nhengo.

Contraindications kuti kushandisa zvinodhaka

Kuti tidzivise kuratidzwa zvisingadiwi pashure pokutora "Zyprexa" zvakakodzera Nyatsodzidza mazita contraindications. To avo vanosanganisira:

1. Yakawedzera aikanganiswa mushonga.
2. Depression pakati tsinga.
3. Pakoma.
4. Age kusvika makore 18.
5. With hanya huru inofanira ushandiswe mushonga "Zyprexa" zvinotevera zvirwere uye mamiriro;

• Itsvo uye chiropa kukundikana.
• Yemaziso.
• Chepfari.
• Prostatic hyperplasia isiri yekenza.
• Myelosuppression.
• Phenylketonuria.
• Mutezo ileus.
• Pregnancy.
• Paanenge achiyamwa.

Kana murwere ane dzinenge imwe zvinotevera zvirwere kana zvinhu zvinofanira zvachose kuudza chiremba wako.

Kutora zvinodhaka panguva yepamuviri uye achiyamwa

Kana mukadzi anopedza kurapa ne "Zyprexa" uye pamuviri, unofanira kuudza chiremba wako. The mushonga panguva gestation mwana anofanira kutora chete kana kubatsira kuti mai kudarika dzingangoitika kuchikosha pangozi kuti kukura mwana.

"Zyprexa" - antipsychotic, rinogona kupinda mu mukaka, saka panguva zvinodhaka kurapa haafaniri kuramba kupa mwana wako, zviri nani kuti chinja kuti chakagadzirwa dzichifura.

Dzinenge kurumbidza panguva kurapa

Vanachiremba vepfungwa kazhinji kumisa sarudzo pamusoro zvinodhaka "Zyprexa", mutengo iyo, zvinosuruvarisa riri kumusoro zvikuru. Saka, mumwe remidzanga mapiritsi (. 5 MG, zvidimbu 28) achaita mari 2500 rubles, uye mumwe chinu kuti jekiseni -. 239 kuzora.

Zvinenge zvinodhaka zvose boka iri vanokwanisa rinokonzera pave neuroleptic urwere, uye "Zyprexa" hapana anosara. Panguva kurapika anofanira kungwarira, uye kana paine kusagadzikana kupomba kana tachycardia, arrhythmia, kana vangadikitira, wakawedzera muviri tembiricha, unofanira kuudza chiremba wako.

Clinical kuratidzwa neuroleptic akaipa urwere kunoda kuti mushonga akanga pakarepo chichiregwa.

Vakaperekedza zvekuchipatara ongororo iyo Vakawana kuti kwenguva refu kurapa "Zyprexa" haawanzopiwi achiperekedzwa dyskinesia, izvo zvaida zvokurapa kupindira. Asi usakanganwa kuti pane njodzi akazotevera pakukura ichi.

Kana paine zviratidzo psoriasis, zvakakodzera kuchinja dose nenzira kwayo rutapudzo.

In pamberi "chiropa kukundikana" mishonga Dambudziko kubatwa nokungwarira akaipisisa, kunyanya ne zvibereko AST uye alt. Kana nhamba vanosvika dzinonetsa pamwero, zvakakodzera kuderedza uwandu husingakuvadzi kuti "Zyprexa."

mushonga uyu anofanira kubatwa nokungwarira, kana nhoroondo murwere akanga zvipusha pfari kana kugara pachena kuti zvinoita kuti kudzikisa kufenda pachikumbaridzo.

Kana murwere nemiedzo zvairatidza kwakaderedza nhamba ropa masero machena kana neutrophils, maverengerwe "Zyprexa" yaifanira pasi wezvokurapa achitarisirwa uye nguva nenguva kuongorora ropa parameters. Saka rinoratidza mirayiridzo kushandiswa. "Zyprexa" kunodawo zvaidiwa chaiyo hanya panguva kurapwa kana:

• Pane zviratidzo kudzvinyirirwa kana kukanganisa chepfu mwongo.
• Kuvapo concomitant zvirwere izvo tunodzivisa mwongo chaitika.
• Kana nhoroondo murwere aiva radiotherapy kana mishonga.
• Kuvapo hypereosinophilia.

Munguva experimental Zvidzidzo Kashoma Yokurapa "Zyprexa" achabatsirwa anticholinergic nemigumisiro, asi zvakaitika kushandisa zvinodhaka izvi varwere concomitant zvirwere iri diki, saka kurapwa, kana zvichikodzera, zvinofanira kuitwa nokungwarira uye chete pasi zvokurapa achitarisirwa.

ileus uye up angled yemaziso ndiwo hwaro nokuda nokungwarira kunorapwa zvinodhaka "Zyprexa". Zvakaitwa zvinodhaka riri nechepakati tsinga kunoda pawakaperera nokungwarira, kana zvakafanira mubatanidzwa nevamwe zvinodhaka zvakafanana pavanonzwa.

The mushonga hauna pamwe doro, saka panguva kurapa havafaniri kunwa doro.

Tichifunga kuti munguva pakurapa "Zyprexa" zvingakonzera hope, zvino iyi zviri nani kurega kutyaira motokari, uyewo kuita basa rinoda kunyanya yevasungwa.

How chokubatanidza "Zyprexa" nevamwe zvinodhaka

Muviri huru vanoshingaira wemafuta mushonga chaidzo kuchinja pasi pokudzora FIs kana inducers kuti cytochrome P450, iyo nesimba basa ravo pamusoro CYP1A2. Clearance "Zyprexa" iri kunyanya kuwedzera Varwere vane tsika yakadai sokusvuta, uyewo kutora zvinodhaka "Carbamazepine".

Ongororo Clinical dzakaratidza kuti kana pane chimwe dose ye "Zyprexa" mishonga "warfarin", "theophylline", "diazepam", "Imipramine", ichangobva kuderera mune muviri yaiitwa.

Mawa Kutarisirwa zvinodhaka nedoro hwakazara kunowedzera kunyaradza ehupfumi zvinodhaka, izvo zvingaita kuti kwakaderera yevasungwa.

Co-kutarisira ne "Zyprexa" "fluoxetine" anowedzera kunonyanyisa Kuwanda vanoshingaira fuma olanzapine. Asi varwere vose, chinhu ichi vangava mashoko akasiyana, saka chipimo chemushonga iri kugadziridzwa pamusoro kunyatsoteerera nomumwe.

Kana "Zyprexa" Pfungwa yokuti raitongwa intramuscularly pachiimbwa benzodiazepines, Zvinokurudzirwa kuti kuitisa anonyatsotsvaka kuongorora kunotoda ezvinhu omurwere pachinhu chinovhiringidza ari kufema emuviri uye mwoyo tsandanyama. Zvidzidzo Clinical izvi zvinodhaka mubatanidzwa asina, saka kana zvichibvira kunofanira kudziviswa.

Musumo zvinodhaka hwakazara kukura bradycardia kana akaderera BP, uye kurapa saka vakadaro vanofanira kuitwa chaizvo nokungwarira Varwere vane zvinetso kumwoyo, uye syncope vakanga vakachengeta unopinza donhwe kuitiswa.

Zvinofanira kucherechedzwa kuti kwokubatsira neactivated charcoal kana kugadzirira antacid yekudyidzana kunoderedza kubvisa muitiro "Zyprexa" iri intestinal turakiti, izvo zvinogona kukanganisa kurapwa kunyatsoshanda.

zvokungwarira panguva mushonga "Zyprexa"

Kana pane zvinoita kuti nomumugwagwa kwaitora nguva muviri pamusoro olanzapine, unofanira kuderedza uwandu husingakuvadzi. To zvinhu Idzi dzinosanganisira:

• Female.
• Kuvapo zvinokuvadza zvakadai sokuputa fodya.
• Old zera.

Pasinei chokwadi kuti kazhinji raitongwa "Zyprexa" mushonga uyu zvinoda ngwariro chaiyo varwere vane kana vakanga vachida kuzviuraya.

Panguva kurapa vanofanira kuongorora nezvebasa hepatic transaminases, kunyanya pavarwere vane hepatic vanotaura.

Varwere, ane basa nenyanzvi inobatanidzwa nokutyaira kana kuita mabasa kuti zvinoda vainyatsotarisirwa uye mumisasa, mushonga wacho waakaudzwa nokungwarira. Kana zvichiita, anotsiviwa nomumwe zvinodhaka.

Kana pane zviratidzo neuroleptic akaipa chirwere muchimiro fivha, tachycardia, tsandanyama Makakatanwa, unofanira kurega achitora zvinodhaka.

Sezvo kurapa injini wokusagadzikana "Zyprexa" zvingakonzera wokusagadzikana, kugara chido kutama, zvakakodzera kuderedza uwandu husingakuvadzi zvishoma uye achiita antiparkinsonian nevamiririri.

zvinodhaka analogues

"Zyprexa" analogues ane mapoka maviri:

1. Anoreva zvakafanana, kureva, muchiva kushingaira fuma. boka iri zvinosanganisira zvinotevera mishonga: "Zalasta," "Olanzapine", "Parnasan", "Olaneks", "Normiton".
2. Boka rechipiri zvinosanganisira mishonga kuti muviri womunhu yakafanana pharmacological zvinokonzerwa, akadai "Azaleptin", "Viktoel", "Ketilept", "Kutipin", "Lakvel", "Nantarid", "Safris" uye vamwe.

Kana chiremba wako ushandiswe sezvo mushonga mushonga "Zyprexa", analogues havafaniri kumhanyira tonotora, saka murege kuzadzisa zvinodiwa kuchirapa mugumisiro. chiremba chete anogona kubatsira kugadzirisa nyaya iyi. Chido kutsiva mushonga ringanidzo kwakakodzera, nokuti mushonga "Zyprexa" mutengo zvakakwirira chaizvo, asi kugona kwaro achiri zviripo mari.

Reviews kugadzirira

Pari, anenge murwere ose usati kuenda chemishonga kuti mishonga ushandiswe nachiremba, iva nechokwadi kuti wabvunza pamusoro zvinofungwa vaya kare achirapwa kurapwa. "Zyprexa" mhinduro kazhinji ane zvakanaka. Varwere vanosangana kurapa pamwe mushonga, ayo akakwirira kunyatsoshanda pfungwa. Kunyange pashure huru yawapiwa, varwere vakawanda vanoti yokuzvigadzirisa mishonga mushonga haibvumiri chirwere kudzoka uye zvazvo kushanda havapo. Good kundorwisa mushonga nokuora mwoyo, umo pashure nzira yokurapa haisi zvikasawanirwa anoramba, uye pane chido chokurarama.

Zvinofanira kucherechedzwa kuti, pasinei nokuti "Zyprexa" rine nhoroondo dzakanaka, varwere vakawanda cherechedzai kuratidzwa nemigumisiro. Kunyanya kazhinji kunoitika pamusana yokurapa ichi kufuta, anetseka muviri, vamwe vanoti wokusagadzikana uye nechido nguva dzose kuita chinhu.

Kazhinji, varwere uyewo chokunyunyuta pamusoro kukwirira Mari chinodhaka, izvo haabvumiri kuti atore zvimwe zvikamu vemo.

Pari, mumwe chirwere ari zvombo kuvarapi pane vakawanda zvinodhaka, asi chete pashure kuongorora zvizere, chiremba anogona vasarudze mumwe wavo. Saka haumanikidzwi vakazvimirira gadzai kurapa, zvakafanana mushonga vangava zvakasiyana kubatsira varwere. Zvose zvinoenderana zvainyanya ane muviri, vakawanda mamiriro uye kosi yacho chirwere. Izvi anonyanya chokuita gadziriro pakurapa zvirwere tsinga. Zvichengetedze uye vaine utano!