"Teopeka" (300 MG): mirayiridzo kushandiswa, zviratidzo, mugadziri

Vanhu vane asima, anoziva nguva sei kukosha kubatsira bronchospasm. Dzimwe yakarurama chiito ichi ezvinhu akaoma anogona kuponesa upenyu. A rinokosha pakuita vanhu kubva zvemapapu matambudziko vachiridza bronchodilators.

Description rekugadzirira

"Teopeka" (300 MG), mirayiridzo kushandiswa iyo kunoratidzwa bepa iri Mahwendefa chena ploskotsilindricheskoy dzeraundi chimiro, izvo vari kugara mu kurongedza gandiwa. The chikuru vanoshingaira wemafuta zvinodhaka ndiko theophylline. wevasungwa dzaro chete piritsi kwegadziriro fomu iri 300 MG.

mushonga uyu sei?

By yaro pharmacological kuitwa theophylline, iro rinobva purine, ine zvichivhiringidza zvainoita phosphodiesterase. The kushingaira wemafuta mushonga kutigumbura chaiyo purine receptors, kunomutsa Camp kuunganidza mu zvinyama depots, lowers mano kumeso tsandanyama rinenge kuti chibvumirano, kuderedza uwandu vakasununguka karusiyamu ions, izvo tama kuburikidza muchitokisi membranes.

Kunoonekwa akazivisa vasodilating kushanda kugamuchira "teopeka" gadziriro (300 MG). Mirayiridzo yokushandisa anotsanangura pfuma sechinhu simba pamusoro peripheral nemidziyo ropa. Theophylline anowedzera ropa riyerere kuburikidza renal hurongwa, kunoita kutandara pamusoro Árbol kumeso tsandanyama uye ropa midziyo. Uyewo, Zvakaitwa vanoshingaira zvinoriumba inozivikanwa se munyoro diuretic. Theophylline kunodzivisa kusunungurwa zvinhu nekubuda, Nokumukira ane sema mhinduro uyewo kunowedzera kutsiga pedanda rechikepe masero membranes. Kana murwere hypokalemia vanoshingaira fuma unokura kufefetedza.

Theophylline kunobatsira normalize kushanda kufema, simba iri runoenzanirana muzinda muuropi, zvichiguma nani ropa okisijeni saturation, izvozvo zvinoderedza wevasungwa kuti carbon dioxide. Drug "teopeka" zvinoita diaphragm, zvichiita kuti kucheka. It kunowedzerawo kukosha chinoratidza mucociliary Clearance basa rinowedzera kufema uye intercostal tsandanyama.

Theophylline kunotungamirira dzose ropa mikrotsirkullyatsiyu kunoderedza thrombus inotungamirwa, yakananga chinhu anovanza uye anobvisa aggregation kuti platelet masero. mushonga uyewo anovandudza chokubuda ropa quality, anowedzera kuramba deforming erythrocytes zvinhu.

"Teopeka" (300 MG), nokudaro achidzikisa yose kumanikidzwa iri pulmonary riparadzirwe, uye kunoderedza kurwisa iri pulmonary vascular hurongwa. Somugumisiro, mataurire ganda integuments, itsvo uye uropi kunoderedza. Somugumisiro kugamuchira theophylline akacherekedza kweiyi ropa aibuda coronary, ikawanda cardiac basa, nokuwedzera kunoshamisa masero myocardial inoda okisijeni, unoraramisa kurova kwemwoyo, simba mwoyo sunga yakawedzera.

Pharmacokinetics uye pharmacodynamics zvinodhaka

Pashure murwere akatora piritsi pamwe theophylline, nefuma wefodya kubva nemudumbu zvachose. Food drink ane zvainoita mwero Absorção de Água zvinodhaka, asi ukuru Absorção de Água uye Clearance anoramba kuzochinja. Sezvo yeplasma anosunga 40% yezviri fuma. Theophylline muviri kunoitika muna chiropa kubudikidza cytochrome P450.

Excretion pakati metabolites achibudiswa basa muchimiro nomukombiyuta itsvo, asi 10% of zvinodhaka panobviswa kwaro yepakutanga chimiro. Vamwe Zvinhu kuchikosha zvainoita muviri kuti theophylline. Kuputa, akatora vamwe mishonga, Mishonga tsika, comorbidities, zera, vakakwanisa kuchinja kuti kupanana yezviri fuma mumuviri womunhu. Kuderedza Clearance pamusoro theophylline iri kuchengetwa zvemapapu edema, chiropa chirwere, COPD, uye mumwoyo kukundikana.

Ndiani anogona kugamuchira chokushandisa ichi?

Pane zvimwe zvinhu izvo "teopeka" (300 MG). Mirayiridzo kushandiswa kurondedzera zvinotevera zvirwere:

• obstructive bronchitis mu chisingaperi chimiro;
• hope kufema;
• emphysema;
• asima;
• pulmonary neBP;
• pulmonary mwoyo.

Uyewo, kuti zvinodhaka "teopeka" nyaya dzinovaka chinogona kushandiswa pachiimbwa zvimwe zvinodhaka pakurapa renal edema hunhu. Varwere cherechedza yakakwirira kunyatsoshanda ari mudziyo wayo kugamuchirika nokuda kurapwa kwezvirwere ari kufema hurongwa.

Contraindications

Zvisinei, mushonga uyu anogona kushandiswa kwete vose, nokuda kuvapo wandei anonyevera kubva mari. "Teopeka" contraindications ndeinotevera:

• Hemorrhagic Kurohwa mhando;
• pfari;
• ropa kubva nemudumbu munhau;
• urikanwi inotungamirwa ari zvomudumbu zvomukati;
• tachycardia mukuru severities;
• neBP kana hypotension;
• hypersensitivity;
• gastritis, achiperekedzwa yakakwirira acidity;
• Vana kusvika nemakore 12.

In pamberi dzinenge imwe syndromes izvi kana mamiriro zvinodhaka theophylline vanofanira kusiya

nemishonga

Pane chaizvo boka guru rutivi-anokonzerwa kutora "teopeka" gadziriro (300 MG). Mirayiridzo kushandiswa migove yavo systemic kuratidzwa:

• kusagadzikana tsinga: nomusoro, dzungu, hope nenyonganiso, kupinduka pinduka, vakawedzera kufunganya uye kushatirwa, chakamira pakunodengenyeka zvine;
• dysfunction kwemwoyo uye ropa midziyo: tachycardia, arrhythmia, hypotension, vakawedzera kakawanda angina kurwiswa, hwenhema angina;
• kutyora gastrointestinal Muzvarirwo inoshanda: svoto, gastralgia, kurutsa, chirungurira, reflux, exacerbation maronda, manyoka, ungaderedza havi;
• kuratidzwa neutachiona: ganda mapundu, fivhiri, kuvaviwa;
• nezvimwe yaivhuvhuta zviitiko kutora zvinodhaka kwaicherechedzwa: tachypnea, albuminuria, wakawedzera diuresis, kurwadziwa sternum, hematuria, Flushing, wakawedzera vangadikitira, gipoglekemiya.

Kazhinji, kurangwa ari dose kutapudzwa kurutivi migumisiro ipfupi kana kunopera zvachose.

Sei kutora zvinodhaka?

Zvinoreva kubva bronchitis, akadai "teopeka" vanotumirwa chete kuburikidza nokupinda chiremba uye chipimo chemushonga dzavo anosarudzwa nomunhu. Paavhareji daily Nome vakaenzana 400 MG theophylline. Kana murwere anotakura mushonga zvakanaka, ipapo mazuva 2-3 kubva dose kurapwa rokutanga, inzwi yakawedzera 25% uye zvakare nachiremba wacho kungwara.

Pamusoro kugamuchira zvinoreva kubva bronchitis "teopeka" mune zuva dose kuti asingasviki 900 MG theophylline kugutsikana kudzora hakusi zvakakodzera muropa murwere. Kana iwe tarisa kuratidzwa kudhaka, kudiwa kwokukurumidzira kumisa kutonga padanho wevasungwa huru vanoshingaira pazvokudya muropa. Best vaiona zviratidzo 10-20 micrograms por Rine mamiririta. Kana theophylline zviri ropa murwere ari kupfuura dzose, ivo vakachengeta kukura kunaka siyana. Muchiitiko ichi zvakafanira yokuderedza uwandu husingakuvadzi zvinodhaka, uye muviri nokuita simba.

Pangava imwe ovhadhozi?

Bronchodilators akadai "teopeka" anogona kukonzera zvakakomba kusagadzikana kwemuviri iri huye ovhadhozi. Kana zvakanaka vachiwirirana mwero zuva ari kugamuchira achishandisa zvinotevera zviratidzo angamuka:

• ungaderedza havi;
• kushaya hope;
• manyoka;
• ventricular arrhythmias chimiro;
• tachycardia;
• ropa pamusoro zvomudumbu hurongwa;
• tachypnea;
• tremor;
• kufunganya;
• Flushing ganda ;
• zvakawedzera excitability;
• kutya chiedza;
• kurutsa ropa.

Rinogonawo kuva zvakakomba chepfu, izvo kunooneka pacharo zvinotevera zviratidzo:

• panowanikwa zvipusha pfari;
• hypokalemia;
• renal kukundikana, myoglobinuria;
• hypotension;
• kuvhiringidzika;
• hyperglycemia;
• metabolic acidosis.

Zvokuita panyaya iyi?

Kana paine uchapupu zviratidzo kana nokufungirana wavo vanofanira kuita gastric lavage, kupa murwere chelators, laxatives, zvinodhaka, uyewo kuronga diuresis plasmasorption, hemodialysis uye hemosorption. Kana murwere ane pfari, zvino inokurudzirwa kusuma okisijeni kurapa uye intravenous "Diazepam" ichabatsira zvinobudirira kusunga kupambwa. Kana iziviswe svoto uye kurutsa vanofanira kugadza "Ondansetron" zvinodhaka intravenous uye "Metaklopromida".

Chii mishonga hazvigoni kubatanidzwa "teopeka"?

Bronchodilators akadai "teopeka 'havafaniri kutora pamwe macrolide-asingaurayiwi" Allopurinol "," cimetidine "," Lincomycin "," isoprenaline ", uyewo mukanwa nhumbu nekuti zvinodhaka izvi kubatsira kuderedza Clearance kuti theophylline.

Hazvina varumbidzwa chokubatanidza yaunodya kuti Beta-blockers, kunyanya dzisiri zvokusarudza, pamwe zvinodhaka "teopeka", kubva izvo zvinogona kuva Árbol constriction uye kuderera bronchodilator mugumisiro theophylline.

Kana "teopeka" aishanda pamwe "Furosemide" zvine caffeine uye zvimwe zvinhu inotokonya Beta-2 adrenergic receptors, basa rayo zvikuru zvinoriumba iri yekudyidzana ichiwedzerwa. Kana pamwe theophylline "Aminoglutitemidom", mashoko okutanga anotanga nokushingaira yabudiswa kubva mumuviri wayo kunyatsoshanda madonhwe.

"Acyclovir" anogona kuwedzera wevasungwa huru vanoshingaira chirungiso "teopeka" uye anowedzera zvisina migumisiro mutambo wayo. Similar mananara zvinochengetwa kana co-raitongwa ne theophylline zvinodhaka "Dialteazem", "Felodipine" "Verapamil", "Nefedipin". mishonga izvi regai kushandura bronchodilator Chaizvoizvo Zvisinei, murwere anogona kuona zviratidzo nenjodzi kana zvikashandiswa zvakapfurikidza.

Fuma "Disulfiram" vanokwanisa kuwedzera theophylline ropa kuti kutsoropodza zviratidzi ngozi muchetura lesion. "Propranolol", kusiyana, kunoderedza "teopeka" Clearance yezviri fuma. Kuwanda theophylline iri yakawedzera somestnom kugamuchirwa waro "enoxacin" uye fluoroquinolones. Kana theophylline kurapa zvinoderedza kuti kunyatsoshanda kuti lithium munyu.

Kana ikashandiswa kurapwa ne "pentobarbital", "Carbamazepine", "Isoniazid", "rifamycins", "sulfinpyrazone" akawedzera Clearance "teopeka" uye kunoderedza kushanda kwayo. Kana concomitantly ne theophylline "phenytoin" pane yakawiriranwa chinovhiringidza kuti vanoshingaira chinoumba muropa murwere.

nhungamiro ava kukosha, vachifuratira pavo rizere nezvinetso zvoutano. Saka, asati kutora "teopeka", verenga mirayiridzo nokungwarira. Uye kana uri kubatwa nokuda chero pamusoro mishonga, bvunza chiremba wako.

How kutenga zvinodhaka uye kuti mushonga ndewe?

Tichitarira dzakakomba contraindications uye divi zvinokonzerwa zvinodhaka ichi, "teopeka" yakabudiswa muna Pharmacies chete mushonga.

Drug "teopeka" mutengo ndiwo avhareji kuRussia ndicho 160 rubles, anounzwa Pharmacies kubudikidza vagadziri siyana. Humwe howa - mushonga "Borschagovsky cpp SPC" wokuUkraine nemakambani anogadzira mishonga. mutengo wayo 155 rubles. Russian kugadzirwa "teopeka" chinodhaka, 300 MG rinoitwa panguva emakambani ane JSC "Pharmaceutical bhizimisi" uye "Valens". zvinodhaka izvi mari 290 rubles uye 190 rubles azvaitwa.

Kazhinji, mushonga "teopeka", mitengo unogamuchirwa, vaiona inokwanisika mushonga dzakawanda vomunyika yedu. In tichienzanisa dzomuzana European chokushandisa uyu isingadhuri zvikuru. Russian kugadzirwa "teopeka" chinodhaka akariita inokwanisika.

Rinotinyevera kana kunwa mushonga

Kana kugamuchira "teopeka" chinodhaka, wongororo zvacho zvakanaka, tinofanira kuteerera mashoko anotevera. Kana murwere ane coronary kana cardiac insufficiency, atherosclerosis, cardiomyopathy, gastrointestinal urikanwi, chiropa chirwere, kenza yeprostate, oesophageal reflux, pamuviri, hypothyroidism kana yakawedzera propensity kuti pfari, zvinodhaka theophylline inofanira kubatwa nokungwarira.

Children pasi makore 12 uye varwere vakwegura "teopeka" akagadzwa kashoma.

Zvichida kushandisa rectal siyana zvinodhaka, asi vanofanira kushandiswa nokungwarira mu pathologies pamusoro mugaranhoko uye manyoka syndrome. Varwere muropa kusvuta pfungwa richikwidibira mugumisiro kurapwa "teopeka".

Vaiona inadmissible kwemajoini kurapwa theophylline uye xanthine nomukaka. Kana murwere vakwegura akaratidza concomitant zvirwere, chaikonzerwa noutachiona, chiropa chirwere, mwoyo uye ropa midziyo, chiremba kugadzirisa dose wemishonga.

Ndinogona kutora mushonga vakadzi vane pamuviri?

Mukadzi ane pamuviri wacho medicament inoratidzwa kuti kuvapo kwazvo zvairatidza kubva theophylline anokwanisa zvinopfuura placenta. Kana kugamuchira "teopeka" kunoratidza mai anoyamwa, kuti lactation anofanira vakarega.

Chinyorwa ichi itsanangudzo shanduro mirayiridzo yakakwana, iyo wanamatira mushonga "teopeka". Zvinofanira kuverengwa vasati kurishandisa. Kana paine chinhu muri kuvhiringidzika kana mubvunzo, bvunza chiremba wako.