Shanduro dzeRussia nedzimwe nyika dze "Erythromycin": tsanangudzo, mitengo, maitiro. Ndezvipi zvingatsiva zvinodhaka zvichibva pana erythromycin?

Muzvirwere zvebhakitiriya zvakagadzirisa chirwere chekupemha, genitourinary sphere kana dzimwe nhengo, vanachiremba vanoronga maitiro anonzi antibacterial agents. Kuti abvise zvirwere zvishoma zvegam-positive kana gram-negative, alpha-hemolytic streptococcus, mycoplasma, chlamydia nezvimwe mabhakitiriya zvinogona kuitwa nekubatsirwa kwe "Erythromycin". Nhoroondo dzechirwere ichi nemishonga yakafanana inoshandawo zvakare.

Zviratidzo zvechombo

Mapiritsi "Erythromycin" ane muhutano hwahwo 500 mg wezvinhu zvakafanana. Iko mushonga unorwisa mabhakitiriya uri muboka re macrolide. Chiito chayo chinobva pakuziva kuti inokwanisa kukanganisa maitiro e peptide zvisungo pakati peamino acids uye kudzivisa nzira yeproteinini inonzi pathogenic microorganisms. Iyo haina kuchinja nucleic acids munzira ipi zvayo.

Asi iyo inoshandiswa pfuma erythromycin mumatumbu emuviri inoparadzirwa zvisina kufanana. Inounganidza muitsvo, chiropa uye spleen. Kuwanda kwemishonga inorwisa mabhakitiriya mumuginhi uye bile yakawanda kakawanda kupfuura yeplasma yeropa. Erythromycin inokwanisa kupinda mukati memaviri emakirini, mapapu, exudate wepakati, nzeve, kuchengetedzwa kweprostate gland, synovial uye ascitic fluid, chirwere chechirema.

Zviratidzo: mune zviitiko zvipi mushonga unorayirwa

Usati watarisa zvakafanana zve "Erythromycin", unofanira kunzwisisa zviratidzo zvekutora mhinduro iyi. Inogona kushandiswa mumamiriro ezvinhu apo chirwere ichi chinokonzerwa nema microorganisms anonzwisisa iyi antibiotic. Izvi ndizvo zvinotevera:

Scarlet fever;

- Gonorrhea;

- Diphtheria;

- conjunctivitis muchecheche;

- trachoma;

- brucellosis;

- Anogunzva chifuva;

- Erythrasm;

- zvipembenene zvepamusoro chekufuridzira chepamusoro (bronchitis, tracheitis, pneumonia);

- primary syphilis;

Urogenital zvirwere mumadzimai anotarisira;

Uncomplicated chlamydia;

- zvipembenene zvinotapukira zvezvikamu zve ENT (otitis, sinusitis, tonsillitis);

- mabhakitiriya matsiyamu ebhiariary (cholecystitis);

- maziso ekuona (mucosal matambudziko);

- pustular zvipembenene paganda, kuberekwa, trophic ulcers, kupisa.

Varwere vane rheumatism vanoshandisa "Erythromycin" (zvakafanana nemishonga inokodzerawo) kuitira kudzivirirwa kwekuvandudzwa kwezvirwere zve streptococcal. Anogadzwawo kuti aite mazino, panguva yekugadzirira kushandiswa, asati apera.

Zvingaita zvinotsiviwa nemushandi

Kana chiremba, paanopa kurapwa kwevarwere, anotaura kuti mishonga ine chinhu chinoshingaira erythromycin inodiwa, zvino munhu wacho angasarudza nzira yakanakisisa kwaari mu pharmacy.

Iyo inogona kuva mahwendefa e "Erythromycin" ane chipingi chinonzi enteric. Uyezve, muzvinamori anogona kurumbidza mushonga we "Erythromycin-LECT", "Erythromycin Phosphate". Uyezve pakutengesa unogona kuwana mazano "Eryfluid", "Erythromycin-Ferein", "Synerit", syrups "Grunamycin", "Ilozon".

Kana zvichidikanwa, chiremba anogona kupa chirongwa che antibacterial agents nechimwe chinhu chinoshanda. Izvi zvinoitika mumamiriro ezvinhu apo murwere ane zvinopesana nekushandiswa kwezvinodhaka zvakaitwa maererano ne erythromycin. Mishonga inotevera inorwisa mabhakitiriya inogona kurongedzerwa: Clacid, Macroben, Sumamed, Kubva kuChirungu, Azithromycin, Azax, Zitrolide.

Rwendo rwezvinyorwa

Usati watanga kunwa mushonga wepakutanga kana Erythromycin analogues, unofanira kuziva kana iwe unogona kushandisa madhiragi aya. Mushure mezvose, urongwa hwemamiriro ezvinhu mavanofanira kusiyiwa hwakawandisa. Zvose zvinosanganisira:

- lactation period;

- kurasikirwa kwekunzwa;

- yakagadzirwa hypersensitivity kune erythromycin;

- chido chekugamuchira mari "Astemizol" kana "Terfenadin".

Kana nhoroondo ye jaundice, arrhythmias, renal kana kushaya simba, kuwedzerwa kwemukati we QT pane chirwere chemoyo, zviri nani zvakare kuitora.

Kunyoresa zvinetso nekutora mishonga

Izvo zvinodiwawo kuramba kuramba kushandisa mishonga kana zvimwe zvinetso zvingaitika. Muchiitiko ichi, zvinodikanwa kusarudza mafananidzi e "Erythromycin" nemumwe chinhu chinoshanda. Pakati pemigumisiro inogona kuva:

- kugadzirwa kweganda (rash, urticaria);

- eosinophilia, kuwedzera basa rehepatic transaminases;

- chirwere, kusuruvara uye kurutsa;

- kurwadziwa munharaunda yedumbu;

- pseudomembranous enterocolitis;

- cholestatic jaundice;

- kutaridzika komubvumo munzeve;

- kunzwa kurasikirwa;

- Vamwe vanhu vane tachycardia, ventricular arrhythmias mushure mekugamuchira;

- Muzviitiko zvisingawanzoitiki, anaphylactic shock occurs.

Mafomu ekubudiswa kwemari

Iwe usati waenda kune homisi uye unotora mhando yemazuva ano kumushonga we "Erythromycin", unofanirwa kusarudza kuti ndeupi rudzi rwechirwere chaunoda. Paunotengesa, unogona kuwana mahwendefa, mafuta, mafuta kana granules pakugadzirisa kwekumiswa uye lyophilizate yejojo.

Muzviitiko zvakawanda, mishonga inorayirirwa nenzira yemapiritsi. Asi kana varwere vachida kurapwa kwakasimba, uye kurapwa kunoitwa muchipatara chechipatara, vanogona kupa chirwere chinoputira. Mhinduro yacho inogona kujowa nejasi rinononoka kwemaminitsi 3-5 kana kudonha-zvichienderana nezvinorayirwa nachiremba.

Mafuta anorayirwa kuitira kurapwa kwepustular zvipembenene zveganda, kusanganisira vana vechidiki. Inofanira kushandiswa kune zvipembenene zvose. Kana zvinetso zvepabonde uye zvinokonzera meso zvinoshandisa mafuta anokosha, izvo zvinofanira kuiswa kune eyelidhi shoma.

Poda uye granules zvakagadzirirwa kugadzirirwa kwekumiswa. Ivo, sekutonga, vanorayirwa kune vana vanoona zvakaoma kuwana dhikidzi inokosha mumapiritsi.

Vakadzi vemuzinda

Kana iwe usingadi kupedza mari yakawanda kutenga zvinyorwa zve "Erythromycin", mahwendefa anogona kutorwa kubva kuRussia kugadzirwa. Mu pharmacy unogona kuwana "Erythromycin-AKOS", yakabudiswa naJSC "Sintez" (Kurgan).

Kana iwe uchida kupinda muchirwere nenzira yejojo, unogona kutenga erythromycin phosphate. Inogadzirwa nekambani yeRussia Sintez.

Uyewo muRussian Federation vanobudisa "Erythromycin-Lect" paTyumen Chemical-Pharmaceutical Plant. Mukuwedzera, chigadzirwa chepakutanga "Erythromycin", chakabudiswa nemakambani eOJSC "Sintez", OJSC "Biosintez", "Tatkhimpharmpreparaty", "NIZHFARM", "Bryntsalov-A" inogona kuwanikwa pakutengesa.

Tumira mifananidzo

Vakawanda vanoramba kubva kugadzirwa, kunyange kana vakanyorerwa mushonga we "Erythromycin". Hazvisi zvakaoma kusarudza analogu yekuiswa, nokuti zvakawanda zvigadziriswa zvinoshandiswa pachishandiswa chinhu ichi chinoshanda.

Kana uchida kutenga mhinduro yekugadzirisa maitiro, iwe unogona kutora "Erythromycin lactobiont", yakabudiswa nekambani inobva kuUnited States. Munyika iyoyo, kusimirirwa kwevana "Ilozon" inogadzirwa.

Simba rekumiswa kwe "Erythromycin-Ratiofarm" inogadzirwa muGermany, munzvimbo imwe chete, granules inogadzirwawo pakugadzira sirasi "Grunamycin".

Mushandi we "Erythromycin-Teva", iyo inowanikwa nenzira yehwendefa kana pfupfu yegadziriro yekusimudzira, inogadzirwa muIsrael. Zvimwe zvinodhura zvinotengeswa kunze kwenyika zvinogadzirwa muIndia. Muma pharmacies eRussia unogona kuwana "Erythromycin stearate" yekugadzirwa kweIndia - iyo ipiritsi ye 125 mg.

Kunze kwekunoreva

Popular inoshandisa mafuta eerythromycin. Shandisa iyi mishonga inorwisa mabhakitiriya semunhu ari kunze. Icho chinhu chikuru chinoshandiswa, sezvinogona kufungidzira kubva kune zita, i erythromycin. Mafuta (analogs anoshandiswa nenzira imwecheteyo semishonga yepakutanga) iri nyore kushandisa. Iyo mujeri inopararira pane imwe nhete yakatsetseka neine tsvina yakaonda uye yakanyatsogoverwa. Kunyatsoronga izvi hazvina kukodzera.

Usati waisa mafuta paganda, zvakakosha kuchenesa dambudziko racho uye ropukuta rikaoma. Mushure meizvi, zvakakosha kufambisa chidimbu cheganda kusvika kusvika masentimita matatu paganda. Mafuta anofanira kugoverwa zvakafanana. Mhedzisiro inoitika kana iyo inoshandiswa kwemavhiki maviri kusvika 4 kana pazuva. Kushandisa urongwa uhwu, unogona kubvisa maitiro emakore ekuyaruka.

Iwe unogonawo kushandisa sarudzo. Inopiwa pasi pezita rokuti "Eryfluid". Kuti abvise zvitubu, vanachiremba vanokurudzira kuita zvipfeko kana kumanikidzwa nemugadziro uyu. Kuti uite izvi, zvakakosha kuvhara jira kana utopi hwekotoni nemhinduro uye kuishandisa kumatambudziko munzvimbo ye5-15 maminitsi. Kukanganiswa kwakadaro kunofanira kuitwa kwevhiki mbiri kusvikira katatu pazuva. Asi kuti kuwedzerwa nguva yechirongwa chacho hazvidikanwi nekuda kwedambudziko rekutsamwa.

Nhoroondo dzekunze kwenzira

Vamwe vanhu havasi kuvimba nezvinhu zvishoma zvekushandisa uye vari kutsvaga chizvarwa chitsva che "Erythromycin" analogue. Imwe yenzira dzinozivikanwa ndeyeZinerit. Izvi zvinoshandiswa pamusana pe erythromycin uye zinc dihydrate acetate. Iyo purafura ine mabhodhoro maviri. Chimwe chine mishonga inoshandiswa, uye imwe ine ine solvent. Pakati peizvi, munhu wose ari oga anokwanisa kuvepa. Inokwanisa kukanganisa kuwedzera kwezvipenyu izvo zvinokonzera maronda.

Chirwere ichi "Klindovit" chinowanzoshandiswa semufananidzi wemafuta, iyo yakakosha iyo erythromycin. Zviratidzo zvekushandiswa nemigumisiro mukati mazvo, zvisinei, zvakasiyana, nokuti mishonga inogadzirwa pamusana pezvinhu zvakasiyana-siyana zvinoshanda. Gel "Klindovit" rinoshandiswa chete kurwisana nemakwenzi. Nzira yekurapa inopedza mavhiki matanhatu.

Kurapa mishonga, mapfupa, mashekeri, vanachiremba vanokwanisa kukurudzira gel "Dalatsin". Iyo yakakosha inoshandiswa mairi, uyewo mumushonga we "Klindovit", ndeye clindamycin.

Kushandisa antibacterial suspensions

Kana zvichidiwa, vanachiremba vanorayira vana antibacterial zvinodhaka muchimiro chekumiswa, uye mune dzakawanda iyo inonyanya kushandiswa inonzi erythromycin. Analogues (mirayiridzo yekushandisa inobvumira kushandiswa kwemashoko akadaro, kunyange pakurapa kwechecheche) vanachiremba vanosarudza pakuziva kwavo.

Nyanzvi inogona kupa kurambidzwa kwe "Ilozon" kwezvirwere zvepamusoro chekufema kana urrogenital system. Nhamba yakasarudzwa zvichienderana nehutatu hwemudiki. Vana, zvichienderana nekuoma kwemamiriro acho ezvinhu, inogona kurongerwa kubva pamakumi matatu kusvika ku50 mg yemishonga pa kilogram yemuviri wezuva nezuva. Iyi yero inorayirirwa kune varwere vane makore 4 kusvika 18, kunyange zviri nani kune vechidiki kutenga mishonga mufomu yebheteti. Uye vacheche vacheche, vasati vava nemwedzi mitatu, vanorayirwa 20-40 mg yekumiswa kwe kilogram imwe yehuremu hwavo. Mumatambudziko akaoma, muyero unogona kupetwa kaviri.

Panzvimbo pe "Ilozon" agent, kusungurudza "Synerit", "Eomycin", "Grunamycin" nezvimwe zvigadzirwa zvakaitwa pachishandiswa chinhu chinoshandiswa erythromycin chinogona kurongerwa. Nhoroondo dzinotorwa nenzira imwechete uye pamwe chete nezviratidzo zvakafanana neErythromycin.

Mutengo Kuenzanisa

Kana uchienda kune homisi, vanhu vazhinji vanoda kuziva mberi kwekushandisa mari yakawanda. Ichavimba chete nemhando ipi yemishonga inorayirwa nachiremba. Kana iwe ukatenga "Erythromycin" inobudiswa mumusha, unogona kuchengetedza zvikuru. Kuiswa kwepiritsi 10 ye 250 mg kunodhura makumi mashanu makumi mashanu. Bhodhoro re lyophilizate muhuwandu we 100 ml rinotora mabhuru 14 chete.

Erythromycin mafuta anonhuwirawo haasisina mari. Kuti tubhuti ine simba re 15 g inofanira kubhadhara anenge makumi mana nemaviri. Asi mishonga "Zinerit" inodhura kakawanda zvakare: 30 ml yemishonga inodhura mabhiriki 518. Tube gel "Klindovit" inenge 289 rubles. Chishandiso "Dalacin" chichadhura zvishoma - nokuti iwe uchafanira kubhadhara makumi mapfumbamwe makumi matanhatu.

Nhoroondo dze "Erythromycin" mu mahwendefa, akaitwa pamusoro pezvimwe zvinhu zvinoshandiswa, zvichavawo zvakanyanya kudhura. Semuenzaniso, mapiritsi "Sumamed" (500 mg Nha. 3) achatora makumi mana nemakumi mana nemakumi mashanu. Asi mushonga we "Macropen" unodhura mabhiriyoni 246. Mari iyi inofanirwa kubhadharwa kweplate yemapiritsi 16 e 400 mg.

Kubudirira kwezvinodhaka: kuongororwa kwevanhu

Zvakaoma kuenzanisa kubudirira kwekutora antibacterial agents. Mushure mezvose, chimwe chinhu chakashanda chinoshingaira kurwisa huwandu hwezvinyorwa zvisinganzwisisiki. Asi kana iwe uchida kurapa zvirwere zvinokonzerwa nema microorganisms, izvo zvinogona kukanganisa erythromycin, zvino ichi chinodhaka chinonzi chimwe chekanakisisa.

Pasinei nemutengo unotengesa, kubudirira kwayo kunoramba kwakakwirira, iyo inotsigirwa nehuwandu hwekuongorora. Zvechokwadi, pakukumbira kwevarwere zvinogona kushandiswa nezvimwe, zvinodhura, zvinoreva. Asi izvi, maererano nenyanzvi, hazvizosimudziri nzira yekugadzirisa.

Mishonga yose inorwisa mabhakitiriya inokurudzira kunwa mamwe mazuva 2-3 mushure mokunge chirwere chacho chiri nani. Kwete chimwe chinhu uye "Erythromycin". Nhoroondo dzinodhakwa nenzira imwecheteyo sechirwere chepakutanga.

Zvichienderana nezviratidzo uye kuoma kwechiitiko chacho, kurapwa kunogona kupera kubva kune mazuva manomwe kusvika ku14. Kune vanhu vakuru, chirwere chemazuva ose chinenge g g. Asi mumatambudziko akaoma, unogona kusarudza uye 4 g.

Hazvikwanisi kuwedzerwa kuyerwa kwechirwere ichi kuti kuwedzere kubudirira pasina kunyanya kudiwa. Mushure mezvose, izvi zvinogona kutungamirira kumigumisiro yakaipa. Pakati pavo, vanachiremba vanoshevedza kurasikirwa kwekunzwa uye kukura kwechiropa chakakundikana.