Nicotinic acid murayiridzo

Nicotinic acid, mirayiridzo yekushandiswa iyo ichakurukurwa munyaya ino, ndiyo vitamini inobatanidzwa muhutano hwehutachiona hunoitwa mumasero ehupenyu uye mushonga wemishonga. Mushonga uyu unowanikwa nenzira yepoda yakachena yevhisi inonaka uye isina kunakidza. Zvakaoma kupedza mumvura inotonhora.

Zvinofanira kunzi kuti nicotinic acid (kana vitamini PP) inonzi vitamini, anti-allergenic, detoxifying uye hypolipidemic agent inokurudzira kuvandudzika kwemakinhydrate metabolism, kuwedzera kwemidziyo yeropa, kusanganisira uropi, kutumirwa kwe okisijeni muzviviri. Inobatanidzwa mumagadzirirwo emasabolism emafuta, amino acids, mapuroteni uye purines, uyewo mumagariro e biosynthesis.

Nicotinic acid, murayiridzo uyo unopa kushandiswa kwevhitamini kusvika pamakumi maviri nemashanu emagiramu pazuva, pakuderera kwepamusoro (kusvika pamagiramu mana pazuva) kunoderedza nhamba ye lipoproteins, triglycerides uye cholesterol muropa.

Ichi chirwere chinokurumidzirwa kubva mumugwagwa wekudya, uye pashure pemaminitsi makumi mana inoshanduka kuva nicotinamide. Mavhitamini ari muchiropa anowedzeswa, anogadzirwa mumatumbo, asi anonyorerwa neitsvo nenzira ye metabolite.

Zviratidzo zvekushandiswa kwezvinodhaka ndezvi: avitaminosis, parenteral kudya, malabsorption, kuora muviri kwakanyanya, kusagadzikana kudya kwemamino acids, chirwere cheGI, kuwedzerwa muviri kunoda vitamini PP, fever, hepatitis, zvirwere zvinotapukira zvisingagumi, uyewo zvirwere zvinotyisa, pamuviri, Kubata, kushungurudzika. Uyewo nicotinic acid, murayiridzo unoshandiswa kushandiswa pamushonga, unorayirwa kuve kukanganiswa kwemashure muuropi, zvirwere zvemidziyo yemigumo, kusanganisira marwadzo avo, zvirwere zvejenitourinary system, polyneuropathy uye microangiopathy.

Nicotinic acid zvinopesana zvinotevera: hypersensitivity kumushonga, gastric ulcer, gastritis, gout, glaucoma, hypotension, vana vari pasi pemakore maviri emakore. Uyewo, nekuchenjerera shandisa ichi chirwere chezvirwere zvehutano hwetachiona, utachiona, enterocolitis, trophic uye isina kuporesa kwenguva yakareba maronda.

Nicotinic acid ine migumisiro yakaipa seyotevera: Hyperemia yeganda, ruvara rweganda rechitsipa, kuoma kwemakumbo emakumbo emeso uye ganda, pamwe chete nerhythmia, chizizi, kusuruvara uye kurutsa, kupisa ganda, myalgia, hyperglycemia, paresthesia. Zvose izvi zvinogona kuitika kana kutora maitiro makuru emishonga. Kana vitamini PP inoshandiswa kwenguva yakareba, chiropa dystrophy, chiso chinonzi hyphenia, asthenia, chizungu uye musoro, kuwedzera kwezviri mukati maAST, APF uye LDH muropa zvinogona kuitika.

Shandisa zvinodhaka mushure mekudya mumazamu anotevera: vanhu vakuru - makumi maviri nemashanu mairigiramu pazuva, vana vanopfuura makore maviri - kusvika pamamiriyoni makumi maviri pazuva.

Inofanira kuyeukwa kuti nicotinic acid inoshandiswa nekuchenjerera pamwe chete neanticoagulants uye antihypertensive drugs. Chero zvazvingaitika, kana yakashandiswa nemimwe mishonga, zvinokosha kutarisana neyanyanzvi.

Mukuwedzera, kushandiswa kwe nicotinic acid kunoda kudya kwakakwana (zvivako zvine methionine) uye nguva dzose kutarisa kwechiropa basa. Nokuda kwekuchera zviri nani mumugwagwa wekudya, zvinokurudzirwa kuti kugadzirira kunotorwa nemukaka.

Nokudaro, nicotinic acid, murayiridzo uyo wakatsanangurwa pamusoro apa, inokosha inobatsira mishonga mukudzivirira nekurapa zvirwere zvakawanda. Zvinotora chikamu mumagadzirirwo emagetsi uye zvinokonzera zvinokonzerwa mumuviri, uye pamwe nekugadzirwa kwemasabolism.