Analogues uye mirayiridzo yekushandiswa kwe "Lomefloxacin"

Chii chinogona kutsiva mushonga wakadaro semishonga seLomefloxacin? Nhoroondo dzechirwere ichi, chinangwa chayo, kushandiswa kushandiswa nekurapa zvinhu zvichakurukurwa pasi apa. Uyezve, iwe uchadzidzira kushandisa zvakanaka sei chigadzirwa ichi, uye muyero ipi.

Mhando yemishonga, hupfumi uye zvikamu

Mumuchina wei pakagadzirwa chigadzirwa chiri kuitwa? Ndepi iri murairo wayo wokushandiswa? "Lomefloxacin" ipiritsi yakaiswa mumablisters uye yakazara mumapepa emapepa pamwe neshoko rinotsanangurwa.

Ndezvipi zvinoita kuti chibereko chacho chibatanidze? Nhengo inoshanda yechirwere ichi iLomefloxacin hydrochloride. Inosanganisirawo mamwe masangano anobatsira.

Kurapa zvinhu zvechirwere

Ndeapi mapiritsi eLomefloxacin? Iyo mirayiridzo inotaura kuti iyo ibhakitiriki inorwisa mishonga yemishonga inhengo yeboka remishonga inorwisa mabhakitiriya-semishonga, iyo, fluoroquinolones, uye inomirira wechizvarwa chechipiri chemishonga iyi.

Chii chinogadzirisa hutachiona hwehutachiona hwemishonga iri mubvunzo? Izvo zvinhu zveLomefloxacin tablet (400 mg) zvakawanikwa nekuda kwekuti chinhu chayo chinoshanda chinogona kukudziridza kuvhara kweDNA-gyrase (ihwo mabhakitiriya enzyme), iyo inopa hukuru. Mukuwedzera, uyu mujeri anovaka chimiro chakasimba (yakaoma) neine tetramer, uye inoparadza kunyora uye kudzokorora kweDNA yemasero ebhakitiriya, anokonzera rufu rwavo runotevera.

Basa rinoratidzirwa remishonga iyi rinoratidzirwa maererano ne-gram-negative aerobic bacteria segonococcus, salmonella, pseudomonas aeruginosa, hemophilic uye mumatumbo, rudha, cholera causative agent, meningococcus, shigella, morganella nezvimwewo. Uyewo, mushonga we "Lomefloxacin" (400 mg) unopedza simba pamaproteni, chlamydia, campylobacter, mycoplasma, legionella, mamwe pneumococci uye staphylococci.

Mumwe haakwanisi kubatsira kutaura kuti ichi chirwere chinoshanda zvakanyanya kupikisa mycobacteria tuberculosis. Iyo inokwanisa kuderedza nguva yekuwedzerwa kwavo, pamwe chete nekugadzirisa kwakakurumidza kweiyo iripo inopinda.

Kurapa kwemaLomefloxacin kunocherechedzwa kunyange nehuwandu hwayo muropa. Zvisinei , kupikisa hazviwanzoitiki.

Kinetic kukwanisa mapiritsi emishonga

Mushonga wacho unobatwa sei? Ko murairo wekushandisa unoti chii? Lomefloxacin ine unyanzvi hwakanaka hwekudzivirira. Mushure mokutora mishonga iyi, nhamba yepamusoro yeplasma yekutungidzirwa inosvika mukati memaminitsi 55-85.

Ne mapuroteni eplasma, mushonga uyu unosunga chete ne10%. Iko inewo kunakidzwa kwezvinhu mumarudzi akasiyana-siyana uye masukisi (kusanganisira genitalia, majoints, mapfupa ekufema, nhengo dzeET, nhengo dzepelvic, mapfupa, peritoneum, maviri ane mutsvuku, nezvimwewo) Plasma.

Inofanira kunyanya kutaurwa kuti mamwe e-lomefloxacin anogadziriswa uye anogadzira zvigadzirwa zvakawanda.

Nguva yekudzoka kwechirwere ichi maawa 9. Inenge yakanyanyisa kuburikidza nechisimba chekudzivirira pamwe chete nomugini (70-85%) uye mhuka (25-30%).

Zviratidzo zvekutsanangura

Vanhu vashomanana vanoziva, asi mumagetsi ekutengesa mishonga hauwanikwe chete mapiritsi eLomefloxacin, asiwo Lomefloxacin + Pyrazinamide + Prothionamide + Etambutol + Pyridoxine. Muchiitiko ichi, zvose zvinotaurwa mishonga zvinoratidzwa kuti zvishandiswe apo:

• Utachiona (purulent chaiwo) eganda, pamwe chete nemhando dzakapfava (kusanganisira kupisa, maronda ane utachiona, nezvimwewo);
• Osteomyelitis;
• Chlamydia uye gonorrhea (kusanganisira blepharoconjunctivitis uye chlamydial conjunctivitis);
• Utachiona hwehutachiona hwemakumbo (somuenzaniso, necholera, maronda, typhoid fever, salmonellosis);
• Zvirwere zvekupumha (kusanganisira kudzokorora kwechirwere chisingagumi);
• Utachiona hwe bile ducts;
• Zvirwere mu genitourinary sphere (somuenzaniso, ne urethritis, prostatitis, cystitis, pyelonephritis);
• Pulmonary tuberculosis (kusanganisira mune zvakaoma kurapwa kwevanhu vanowedzera kufambira mberi maitiro echirwere ichi, pamwe nekuwedzera kukurudzira isoniazid uye rifampicin nekudzivirira chemotherapy);
• Pamberi uye mushure mekuvhiyiwa kwechirwere chetachiona (chete nokuda kweprophylactic zvinangwa).

Zviratidzo zvekupa mapiritsi emagetsi antimicrobial

Muzviitiko zvipi haugone kushandisa mushonga uyu mubvunzo? Izvi zvinotiudzei pamusoro pemirairo yekushandiswa? Lomefloxacin inopindirana kuti ishandiswe apo:

• Kutakura kwe fetus;
• Breastfeeding;
• Kunzwisisika kwezvinhu zvezvinodhaka zviri muboka re fluoroquinolones;
• Pazera duku (zvinogona kugadziriswa kwekuvandudzwa kwemasaga).

Mirairo yekushandiswa

"Lomefloxacin" - mahwendefa, ayo anongoratidzwa chete mumuromo. Vanofanira kutorwa kamwe chete pazuva, pasinei nokudya, kunwa inenge 230 ml yemvura yakawanda.

Nguva yehutano nemishonga iyi inobva pane kuongororwa, uyewo pamusana pekuoma kwehutano uye hunova hwehutachiona.

Kusanzwisisika bronchitis uye bronchopneumonia yemutambo unooma inorapwa neyero yakaenzana ne 400 mg yemishonga kwemazuva gumi.

Mukurapa kwechlamydia (urogenital), kusanganisira mabhakiteriya chlamydia uye gonorrhea-chlamydial zvirwere, varwere vanorayirwa 400-600 mg yemishonga zuva nezuva, pamwe nekureba kwemazuva makumi mana.

Kurapa kwekudzokorora kwepineumonia yakakomba uye bronchitis yemhando isingagumi inoitwa mumutengo wezuva nezuva wakaenzana ne 400-800 mg wejenzi kwevhiki mbiri.

Nehutachiona hwemycoplasmal , mishonga inorayirwa 400-800 mg pazuva, nehuwandu hwekutora mahwendefa mumavhiki matatu.

Zvirwere zvinotapukira zvemuti unoita urinary zvinogona kurapwa ne 400 mg yemishonga. Muchiitiko ichi, kurapwa kwematambudziko asina kuoma kunoitwa kwemazuva mashanu, uye zvakaoma - mazuva 14.

Ne gonorrhea yemhando yakaoma, mushonga we "Lomefloxacin" unorayirwa kuti uite mumutero we 600 mg. Kana chiri chimiro chisingaperi chechirwere ichi, kurapwa kwacho kuchiitwa nenzira yakafanana nehutachiona hwehutachiona. Muchiitiko ichi, mishonga inotorwa mumazai ezuva rimwechete mamwe mazuva mashanu.

Therapy of pulmonary tuberculosis inogona kutora mazuva 14-30 (mune dzimwe nguva kusvika pamwedzi 3). Chirwere ichi chinorapwa neyero ye 200 mg kaviri pazuva.

Mukurwara kwechirwere chechirwere chakakomba kana chakanaka, pamwe chete nevanhu vari kutarisa hemodialysis, "Lomefloxacin" inorayirwa muwandu we 400 mg pazuva, pamwe nekuderedza kwayo kudarika 200 mg.

Phenomena yezvakaipa

Ndezvipi zvakashata zvemapiritsi eLomefloxacin? Dzidziso inoratidza zvinotevera:

• Bronchospasm, yakanyanya kuvharwa kweputum, kusuruvara, kukomba, dysphagia;
• Dyspnea, kurutsa, zvirwere zvokufema, chirwere, dysbiosis;
• Zviratidzo zvakadai semafukari, kuravira kusvibiswa, kurwadziwa kwepamuviri, flatulence;
• Kuwedzera kwehuwandu hwechiropa hunokonzera mishonga, yakaoma muromo, kubuda ropa GIT;
• Kuvhara, arthralgia, mhuru inoputika, kududzirwa kwerurimi, myalgia;
• Pseudomembranous colitis, misoro yepamusoro, kushanduka mukuda kudya, vasculitis, chirungu;
• Kunyunyuta, kuora kwechifukidzo uye kumashure, asthenia, kutya, kunzwa kwesei malaise, kuora mwoyo, kudengenyeka;
• Hyperkinesis, kuneta zvakaneta, kunetseka, kukanganisa;
• Njodzi mumeso, ruzha uye kurwadziwa munzeve;
• Dysuria, kuwedzerwa kwekunaka, hematuria, paresthesia;
• Crystaluria, kutadza kuona;
• Albuminuria, glomerulonephritis, leukorrhea, edema, polyuria, epididymitis, kuoma kunyura, orchitis, kukuvadza kunorwadza;
• Cyanosis, anuria, hypotension, vaginitis, tachycardia, extrasystole, kurwadziwa kwepineineal, bradycardia;
• Kubuda ropa, thrombocytopenia, vaginal candidiasis, myocardial infarction, myocardiopathy, phlebitis;
• Kufambira mberi kwemwoyo kusakatika uye stenocardia, purpura, zvinetso zveperebrovascular, kutema kweganda;
• Pulmonary embolism, photosensitization, kuwedzera fibrinolysis, urticaria, lymphadenopathy, hyperhidrosis;
• Nasal kubuda ropa, exudative erythema (inokuvadza), manzwiro echills, gout, hot flashes;
• Kushaya simba, hypoglycemia, candidiasis, nyota.

Overdose nemapiritsi

Mukana wekudarika kwemahwendefa eLomefloxacin, varwere vane chirwere chinoputika, zvipembenene zvinokonzera zvekudya mumucho mukati, kuwedzerwa kweKT nguva, dutu, kushungurudzika, kuvhiringidzika, uye kuwedzerwa kwekusateerera kwakaipa.

Mukuona kwekuti hemodialysis haibatsiri kana ichingopfuura kudarika, kurapwa kwemamiriro ezvinhu ari pamusoro apa kunobva pane zviratidzo zviripo.

Kuwirirana nemimwe mishonga

Apo Lomefloxacin inosanganiswa neTeofillin, inonzi metabolism inenge isina kupedzwa.

Nenguva imwechete yekutonga kwe- antacids kana sucralfate, chelate complexes dzinoumbwa izvo zvinoderedza bioavailability ye lomefloxacin. Ndokusaka nguva iri pakati pekutora mishonga iyi inofanira kunge inenge maawa mana.

Kushandiswa pamwe chete kwe "Lomefloxacin" uye kukwirira kwakanyanya kwe caffeine kunowedzera hafu yeupenyu hwekupedzisira.

Kana uchibata tuberculosis, iwe haufaniri kutarisa kufanana kwakafanana kwechirwere ichi chiri mubvunzo ne "Rifampicin", zvisati zvingaita kuti uite zvinopesana nezviito.

Kugamuchira pamwe chete kweNSAID kunowedzera kuora kwezvinodhaka uye zvinogona kukonzera kukanganisa.

"Lomefloxacin" inokwanisa kuwedzera kubudirira kweanticoagulants kumuromo wekutonga.

Mishonga, iyo inogadzirisa zvinyorwa zvinopisa, inodzivisa kubvisa kwe "Lomefloxacin."

Mazano Anokosha

Muchidimbu chechirwere, zvinotenderwa kuchinja kudiwa zvinodiwa, zvinoenderana neC QC parameters.

Nokuda kwehutano hwehutachiona, zvakakosha kurega kutaridzirwa kwenguva yakareba kune chero mhepo inonzi ray ray, iyo kusanganisira zuva.

Vitamini maigadziro, kusanganisira zvakasiyana-siyana zvemaminerari ekuwedzera, inofanira kutorwa makumi maviri nemaminetsi mushure mekutora mahwendefa mubvunzo.

Mishonga yakafanana

Mishonga "Lomefloxacin" ine mimwe yakafanana. Nyanzvi dzinofunga kuti zvinotevera zvinotsiviwa nevanonyanya kushandura: Abaktal, Elefloks, Zanotsin, Tsifran, Avelox, Tsiprolet, Zofloks, Cyprinol, Quintor, Ciprofloxacin, Levofloxacin "" Tarivid "," Levotek "," Pefloxacin "," Levoflox "," Ofloxacin "," Norbaktin "," Ofloks "," Norfloxacin ".

Pomefloxacin mapiritsi: kuongorora

Nekuvimbika kwechirwere chinotapukira icho chinonzwisisika kuchizvarwa chechipiri che fluoroquinolones, uyewo pamwe nekusarudzwa kwakakwana kwemishonga yemishonga uye kwenguva yakareba kurapwa, kuongororwa pamusoro pemushandi ari mubvunzo ndeyezvakanaka chaizvo.

Maererano nevanoti varwere, mishonga iyi yakaratidza kuti ine mishonga inobatsira yemishonga inogadzirisa zvirwere zvakasiyana-siyana. Zvisinei, vamwe vashandisi vanoti dzimwe nguva zvinodhaka izvi zvinokonzera kukurudzirwa kwemamwe matambudziko, asi, sekutonga, vanonyatsotumidzwa kana kuti vanozozvitora ivo pachavo shure kwekuguma kwerapi.