Cushing nehosha - chirwere pamwe pituitary hyperfunction

Disease Cushing kana Cushing kwakaita - chirwere icho kukonzerwa kutyora hypothalamus, pituitary uye adrenal mumasero pamwe pokumuka maronda dzakaoma. The chirwere yakatanga rakarondedzerwa H. Cushing muna 1924, uye muna 1932 Cushing akabatanidza kukura kwayo pamwe pituitary adenoma.

The zvinokonzera Cushing nehosha iri basophilic adenoma pamusoro pituitary Anterior akafukidza kana kuwedzera uwandu basophilic pituitary masero. kuchinja izvi kungakonzerwa dzechimwe pfungwa uye kunotevera pfungwa, encephalitis, kwemakemikari anobudiswa zvirwere.

Hwaro chirwere - hyperproduction kuti pituitary adrenocorticotrophic kemikari, iro rinoita nokuwedzera kwetunhu cortisol nokuda adrenal mumasero.

Cushing nehosha - zvekuchipatara mufananidzo

The chirwere hwapedyo zvishoma nezvishoma. Varwere chokunyunyuta pamusoro vakawanda simba, hope, kusakendenga, mberi kufutisa. Kufutisa kunokanganisa vainyanya yokumusoro hafu muviri. Somugumisiro, varwere vakaumba mwedzi chiso, mapendekete azere, hudyu, ane disproportionately mutete, atrophic emberi uye shins. Pane kuoma uye peeling ganda, muviri bvudzi riri gono muenzaniso vakadzi, ane mawa kwebvudzi mumusoro, ivo feminization yevanhu. Paganda mudumbu, mapfudzi, chipfuva ngapaonekwe dystrophic rakafara nokurohwa rwepepuru-ruvara ruvara. Nokufamba kwenguva, kukudziridza tsandanyama atrophy maoko nemakumbo, akaderedza simba ravo. Kukudziridza neBP pamwe renal chirwere, chepfungwa matambudziko uye atherosclerosis.

chirwere Cushing kunoita kuti kutyorwa chicherwa muviri, mugumisiro unova kukura osteoporosis. Nokuda osteoporosis vari misha uye compressed tsinga midzi, pane kurwadziwa mukati wamativi, musana, vakatanga curvature of thoracal nomuzongoza nokuumbwa kyphosis, pathological mitswe. calcium remafuta akawandisa muropa inowedzerawo. Hwakaipa ari Absorção de Água kuti shuga, zvichizoita dzichiri cheshuga. Muitiro unowedzera Kukudziridza ropa, taita achiporesa maronda. Varwere vanotsutsumwa zvepabonde dysfunction, ungaderedza libido uye potency, kuzviratidza kumwedzi zvirwere. Possible netsinga, kuora mwoyo, hypochondria, psychosis.

Pamwoyo hwapedyo hypertrophy pamusoro kuruboshwe ventricular tachycardia, nyanyisa yechipiri neBP. Kana itsvo kudzidza zvinoratidza proteinuria, ungaderedza glomerular filtration mwero uye ropa riyerere renal. Zvichida kukura renal scarring wakareruka kushanda nhengo idzi. Vamwe varwere itsvo Mabwe dzakaonekwa.

chirwere chirwere

chirwere Cushing iri akanzi akabata dehenya X-ray ine matambudziko kudzidza sella, computed tomography yeDehenya, uye adrenal omumuviri, vascular ongororo - angiography. Laboratory miedzo kuona huwandu kemikari cortisol muropa uye huwandu corticosteroid iri weti.

Cushing chirwere - Treatment

Kusarudza marapirwo zvikuru zvinobva mhaka chirwere uye kwokuomerwa ari kurapwa zvinoratidza chirwere.

In tanga ushandiswe mishonga mishonga yokuderedza secretion pamusoro adrenocorticotropic kemikari uye corticosteroids. Anoshandiswa antihypertensive zvinodhaka, symptomatic kurapa. Nzira marapirwo rinovapo kusvika mwedzi misere. Kana pasina zvazviri, yakanyanya siyana chirwere, akarayira mubatanidzwa kurapa zvinosanganisira nemwaranzi mishonga uye kuvhiyiwa (nokubviswa pituitary kana adrenalectomy).