"Cefoperazone + Sulbactam": mirayiridzo kushandiswa, analogs, wongororo

Pari zvino pane akawandisa zvinotapuriranwa, izvo zvinenge zvisingaiti kuti kubata pasina kushandisa mishonga inorwisa mabhakitiriya. Hazvina chinodiwa kuti mushonga aikwanisa kuva kunambwa vakawanda tusingaoneki. Izvi zvinosanganisira "Cefoperazone + Sulbactam." More Aingoziva zvinoratidza kuti kushandisa zvinodhaka ichi.

Release chimiro uye sezvamunoita

The mushonga inowanika sechinhu upfu kuti mhinduro. It chinotarisirwa nomutsinga kana intramuscularly. The achishingaira fuma iri imwe yakawanda ceftazidime 1 g

Drug "Cefoperazone + Sulbactam" (wezvokutengeserana zita - "Sulperazon" kana "Sulperatsef") uye ndezvaiye boka antibacterial zvinodhaka.

The pharmacological zviito zvinodhaka

mushonga uyu ndera nzira zvabatanidzwa. Medicament "Cefoperazone" ndiyo munoremekedza chakarondedzera mushonga. Iye wakange inokanganisa vakawanda Kurovedza uye anaerobic utachiona.

Kugadzirira "Sulbactam" ane kusingarapiki inhibitor kuti Beta-lactamases. Rinovatadzisa kuparadzwa penicillins uye cephalosporins, sezvo mukomboni Exhibits Mubatanidzwa navo.

The medicament "Cefoperazone + Sulbactam" rine kushanda kwayo yaivhuvhuta pamusoro masero kubudikidza zvichivhiringidza peptidoglycan, inova hunokosha chikamu mabhakitiriya masvingo.

Drug yabudiswa kubva muviri munenge 8 maawa weti. The hafu-upenyu maawa anenge maviri. Kana murwere kugamuchira mishonga, kutambura chiropa chirwere, nepo zvinodhaka excretion inowedzerawo.

Code JECFA "Cefoperazone + Sulbactam» - 24.42.11.228. Drug anobudiswa kuIndia.

Zvairatidza kuti kushandiswa kwezvinodhaka

The mushonga inoratidzwa kuvapo zvirwere kunokonzerwa tusingaoneki inonyatsoziva zvinoshingaira fuma. Idzi dzinosanganisira:

• Pharyngitis.
• Tonsillitis.
• Bronchitis.
• kuzvimba mumapapu.
• Lung pute.
• Zvirwere nezvezvimwe zvinetso zvedundira, akadai cystitis, mwandabvu, prostatitis, vulvovaginal.
• Pfava zvirwere.
• Skin zvirwere zvinotapuriranwa hunhu: furunculosis, pyoderma, abscesses nevamwe.

• Zvirwere mukati pejoinhi.
• Sepsis.
• Yomumuzongoza.

The mushonga zvakare sokugamuchira chokudzivirira chiyero kwemabhakitiriya matambudziko pashure kuvhiyiwa.

Kugadzirira "Cefoperazone uye Sulbactam Dzhodas" kunoratidzwawo mu peritonitis, cholecystitis, cholangitis nezvimwe intra-abdominal noutachiona. Chinangwa zvinodhaka yakawanikwa uye nguva yokurapa uye kurapwa regimens zvinofanira kuita chete nachiremba.

Rinoreva "Cefoperazone uye Sulbactam Spencer" anopiwawo nechinangwa muzvidzivirire.

Ndiani hariudzi kushandisa zvinodhaka

Pasinei akasiyana-siyana nezviito, chokushandisa ichi hazvigoni kugamuchirwa pasi zvimwe zvinhu:

• In pamberi hypersensitivity kuti zvinodhaka.
• Panguva pamukaka "Cefoperazone + Sulbactam" Anonziwo contraindicated.
• Renal hepatic kukundikana zvinoda kungwarira chaizvo kushanda.
• In pamberi colitis mune zvomurwere nhoroondo.

Asati atanga kurapwa pamwe zvinodhaka ichi unofanira kuva nechokwadi kukurukura nachiremba wako pamberi contraindications.

Zvisingadiwi migumisiro panguva kurapa

Drug "Cefoperazone + Sulbactam" wezvokutengeserana zita riri "Sulperazon" panguva kunokwanisa kukonzera kuratidzwa zvinotevera nemishonga:

• Kubva nezvezvimwe zvinetso zvedundira zvingamuka hematuria.
• Kumwoyo anogona kupindura vasanyanye neBP kana vasculitis.

• Analysis ropa panguva kurapika kakawanda kuratidza vasanyanye pamusoro Chizenga, akaderedza hematocrit, thrombocytopenia, eosinophilia, leukopenia nezvimwe abnormalities.
• Akaderedza sealbumin mumatunhu.
• Bilirubin encephalopathy mune vana vachangoberekwa vanogona kuva jaundice.
• Pamusoro chikamu nemudumbu anogona dyspepsia, kurutsa, kuda kurutsa, uye pseudomembranous colitis.
• On ganda kuonekwe mapundu, maculopapular mapundu, uye zvikuru kuvaviwa.
• Laboratory netsvakurudzo zvakawedzera dziine chiropa shanda nemiedzo.
• The jekiseni Nzvimbo soreness mishonga iripo, kana dzakabatwa nomutsinga kuburikidza anobudisa mushonga zvishoma nezvishoma - phlebitis.
• Muduku zvichida kuona nomusoro, nefivhiri, uye zvimwe anaphylactic chinja pane nhengo.

At panowanikwa chero kuratidzwa chisingadiwi vanofanira kukurukura nyaya iyi nachiremba wako. Ungafanira hwokufungazve chipimo chemushonga zvinodhaka "Cefoperazone ne sulbactam" kana kukanzura zvachose.

Chii angatarisirwa ane ovhadhozi kurapwa

Kana iwe tora chinodhaka ichi pasi kuzviomesera pokudzora chiremba, asi ovhadhozi haufaniri kunetseka, asi nokuda okuzvibatsira kurapa kazhinji zvichiita. Kana muviri vakagamuchira chinodhaka zvikuru kupfuura zvinodiwa, pangava chetsinga zvinetso, kusanganisira pfari.

Treatment muchiitiko ichi rinoitwa maererano zviratidzo. Inonyatsobudirira ndiyo hemodialysis.

Chipimo chemushonga neMarapirwo zvaiitwa

Kana yakatarwa mushonga "Cefoperazone + Sulbactam" murayiridzo Chinyorwa anokurudzira kuti baya jekiseni mushonga nomutsinga kana intramuscularly. Varwere vakura zuva dose kazhinji kubva 2 kusvika 4 magiramu yezviri chirungiso. mari iyi inofanira kukamurwa muzvikamu zviviri.

Kana murwere ane kwazvo chirwere dose anogona ngazviwedzerwe 8 magiramu, izvo zvinofanira rakakamurwa mishonga pazuva maviri. Kana pasina chokuita nezvirwere, vakawanda varwere, uye nezuva dose iri uwandu 12-16 magiramu kushivirira pasina pachena nemishonga.

Ya ARV pakutsvaga chiremba. Somuenzaniso, apo nyore gonococcal urethritis raitongwa imwe-nguva 500 MG zvinodhaka.

Nechinangwa kudzivirira yematambudziko pashure rokugadzirira kuvhiyiwa chinotarisirwa murwere 1-2 g nomutsinga awa rimwe pamberi oparesheni. dose ichi zvingadzokororwa pashure pemaawa 12. Kana Kuvhiya rinoitwa pamwe mikana yematambudziko akadai chirwere, ari prophylactic Kutarisirwa anopfuurira 3 Mazuva mushure musangano.

Varwere vane kuvhiringidzika itsvo, zvinodhaka "Cefoperazone + Sulbactam" riri basa iri chipimo chemushonga kwete kupfuura 4 magiramu pazuva. Kana paine matambudziko chiropa, dose ipfupi kunyange kaviri.

Sezvo mushonga anogona kupiwa nomutsinga uye intramuscularly, pane zvimwe zvinhu fomu kwayo.

Kana achiita nomutsinga sechinhu solvent nokuda upfu inogona kushandiswa:

• 5% dextrose mhinduro.
• Sesaline.
• mvura chena kuti jekiseni.

Kana achiita nomutsinga, guruva rinopfumburwa mune imwe chinu ikaparara muna 10 ml akakodzera solvent. Zvakafanira kumirira nemukuparadzwa kwakakwana uye mushonga wakawanda zvishoma nezvishoma pamusoro maminitsi 3-5.

Kana kuchadonha mishonga "Cefoperazone + Sulbactam" murayiridzo Chinyorwa anokurudzira 1 giremu yezviri chirungiso. Kuti, zviri chimwe chinu zvazvichanyungudutswa 5 ml mvura jekiseni, uye ipapo kuwedzera aizomupa mhinduro, kuunza wevasungwa kusvika 20-100 MG / ML. Akapiwa chitsama kupedza kuchadonha, kumonyanisa nguva zvingava 10 kusvika 30 maminitsi.

Intramuscular Kutarisirwa wokuparadza upfu angashandiswa kana mvura jekiseni kana yavaibvisa chloride. The reshiyo iri aiwanzoshandiswa sezvinotevera: 0.5 d chigadzirwa kutora 2 ml solvent.

Sezvo kana raitongwa mishonga vanowanzorwara kuitika marwadzo panguva jekiseni site Zvinokurudzirwa kuti vari kugadzirira zvinodhaka mhinduro akawedzera "Lidocaine 2%", asi chete ezvinhu kuti murwere haasi sema kuti zvinodhaka.

Nokuti chero zvirwere majekiseni kupa kunobatsirawo iri nokukurumidza, saka majekiseni vari kutarisirwa mu "Cefoperazone + Sulbactam." Mahwendefa ndiwo nomumugwagwa kwaitora nguva zvikuru.

Kushandisa zvinodhaka muvana

Nendumure vanowanzotambura nezvirwere izvo hapana mishonga nyore kuita. The daily dose yezviri fuma cefoperazone chinoumba kunofanira kubva 50 kusvika 200 MG muzana kilogram muviri kurema mwana. Raitongwa mushonga unofanira kuenzana zvikamu kuburikidza kupatsanura muzvikamu zviviri.

Desirably, daily dose hakuiti pfuura 12 F. Kana mushonga jekiseni bolus, kuti chikwata dose haafaniri kupfuudza 50 MG / makirogiramu.

Vana vacheche zvinogona kupiwa 50-200 MG zvinodhaka paminiti uremu kilogram muviri, unogovera kuva muzvikamu zviviri kuburikidza maawa 12. Yakavakirwa kwemakore akawanda anobatsira pokushandisa kushandisa mishonga vana, zvinogona kunzi mishonga anosvika 300 MG chete kilogram kurema muviri pazuva zvakanaka kuzoregwa vana, kunyange pamberi kwemabhakitiriya yomumuzongoza.

Kushandisa zvinodhaka panguva yepamuviri

Medicine nokuva chirungiso ceftazidime kwakaitwa vakadzi pachinzvimbo chete kana zvakadaro Where kubatsirwa nokuda vanepamuviri mai kanoverengeka kupfuura zvingakanganisa kukura kwemwana. Kana uchida kushandisa mushonga panguva uchiyamwisa, chiremba achaita akakurudzira panguva ino kuti uchatamisa mwana kuti chakagadzirwa dzichifura.

Kudyidzana nevamwe zvinodhaka

Drug "Cefoperazone" riri ayo pharmacological ehupfumi vasina kubatanidzwa ane aminoglycoside. Kana pane kudiwa iri kurapa mapoka aya maviri zvinodhaka, izvo dzakabatwa muchimiro inoratidza yaitonga Via maviri yoga anobudisa mushonga zvishoma nezvishoma.

Co-kwokubatsira mushonga ane thrombolytic, antiplatelet uye NSAIDs kunowedzera mukana ropa.

Nokuti varwere itsvo zvinetso negashiro imwe medicament "Cefoperazone Sulbactam" pamwe aminoglycosides uye diuretics hwakazarawo kukura nephrotoxicity.

Panguva mushonga ne "Cefoperazone" chisingadiwi kunwa doro, zvikasadaro zvinogona kukonzera zvinotevera zviratidzo:

• Svoto.
• Kurutsa.
• Anotemwa nemusoro.
• Tachycardia.
• BP.
• Abdominal marwadzo.

Usati watanga kurapwa pamwe zvinodhaka ichi, iwe unofanira kuudza chiremba wako pamusoro mishonga zvose achitorwa panguva.

Zvokuita kana uri contraindicated rinoreva "Cefoperazone"? Analogs zvingabudirira vomutsiva.

Vamwe nuances kushandisa zvinodhaka

Panguva kurapwa pamwe mishonga iyi anofanira kunyanya kungwarira varwere vaya kazhinji neutachiona zvinochengetwa. Mukana ichi yakawedzera nehanya hwakazara kunyange zvinouraya. Kana panguva mushonga vakachengeta kunyange zviduku neutachiona, mushonga "Cefoperazone + Sulbactam" anofanira kusimudzwa pakarepo uye kuritsiva nedzimwe nzira.

Kana murwere ane kwazvo mwero mhingaidzo of biliary turakiti, chiropa zvirwere uye itsvo, zvinoda munhu dose kuchinja matambudziko. In pamberi renal uye hepatic vanotaura inofanira kugara vachiongorora wevasungwa yezviri zvinodhaka fuma iri serum. Kunyange pasina kuzvidzora dose haafaniri kupfuudza 2 magiramu pazuva.

Mune dzimwe varwere panguva kurapwa ne "Cefoperazone" dzichiri vhitamini K kushaikwa Kakawanda, dambudziko iri akazviratidza vaya vane chakaremara kudya, malabsorption, kana kutambura kwenguva refu nguva iri intravenous dzichifura. Varwere vari kubatwa ne anticoagulants, dzose vanofanira kuongorora kuti prothrombin nguva, uye, kana zvakakodzera, gadzai wokuwedzera yaunodya vhitamini K.

Kana uchida refu yawapiwa, "Cefoperazone", zvinokwanisika kuti kuwedzera Micro-zvipenyu havasi kubatwa medicament ichi. Zvinoda kwenguva nenguva richiona nezvezvabuda zviratidzo zviri kushanda zvomukati, kunyanya chiropa, neitsvo uye hematopoiesis. Izvi zvinokosha zvikurukuru pakurapa neonates, vacheche vacheche uye rokusamhanyira vacheche.

Panguva kurapwa haafaniri uchityaira uye kuita mabasa anoda zvakawanda yevasungwa.

zvinodhaka analogues

Kana isu funga chero mushonga, mapoka maviri anogona kutaurwa kugadzirira iye analogs uye anoreva zvakafanana. For anoreva zvakafanana zvinosanganisira mishonga kuti sezvamunoita kwavo zvakafanana kushingaira chirungiso. Nokuti "Cefoperazone" chinodhaka, aya:

• "Bakperazon".
• "Sulzontsef".
• "Sulmomer".
• "Sultsef".
• "Tsebaneks".
• "Paktotsef" uye vamwe.

Kana isu anofananidza medicament "Cefoperazone" analogs anogona kuva yokuwedzera zvinoriumba, iyo pamwe chete inokosha fuma vane siyanei kushanda. Ndokusaka kusarudza mishonga yakadaro inofanira kuswedera musoro uye kuzvigamuchira chete mushonga.

Rimwe boka analogues Mishonga pamwe chete pharmacological chiito. Kana kutora zvinodhaka "Cefoperazone + Sulbactam" analogues veboka iri:

• Upfu "Azaran" nokuda intravenous majekiseni.
• "Axons."
• Upfu kuti jekiseni "Bestum".
• "Vitsef".
• "Klaforan".

• "Kefoteks".
• "Tsedeks" capsules.
• "Tsemideksor" (Mahwendefa).
• "Tsefantral" uye vamwe vakawanda.

Kunyange chete pharmacological zvinokonzerwa zvinodhaka nokuda vanoshingaira dzakasiyana zvinhu zvinogona kuva zvakasiyana migumisiro iri muviri, saka regai kusarudza mushonga yavo, zvichibva mirayiridzo kushandiswa.

Testimonials

varwere Avo vasina kamwe akarwawo "Cefoperazone + Sulbactam" chinodhaka nokuda kurapwa kwezvirwere zvinotapuriranwa, akaona kumusoro kunyatsoshanda kwayo. Vakawanda vanoti genitourinary noutachiona rinorapika nokukurumidza uye pasina matambudziko.

Momma vana siya aifarira zvinodhaka "Cefoperazone" wongororo zvakarurama zvakanaka. Vakaona kuti vana kushivirira mushonga zvakanaka kunyange pamberi co-morbidities. Zvinofanira akayeuka kuti kurapa kwakadaro kunofanira kuitwa chete muchipatara, kunyanya vachangoberekwa.

The kubvuma chero mushonga inoda yakawanda basa zvomudumbu hurongwa. Kuti tirambe pakuenzanisa microflora, zviri chinodiwa panguva kugamuchira mishonga yakakodzera Somuenzaniso, "Linex". mubvunzo uyu anogona nguva dzose kukurukurwa nachiremba wako.