Allopurinol, murayiridzo kune chiratidzo, chipimo chemushonga, nemishonga uye contraindications

"Allopurinol", mirayiridzo kutaura asunungurwa muchimiro mahwendefa 100 MG. Rinoreva mushonga mishonga zvinoreva protivopodagricakih kuchititadzisa kubatana kwetunhu uric acid. Maererano mamiriro "allopurinol" chiri analoginen pamusoro hypoxanthine, inhibitory chikuru enzayemu iyo paChikoro paumbwe uric acid. The mushonga "allopurinol" wongororo ngaadarowo zvarinoita pokufa uric asidhi munyu, pamusoro kugumiswa dzidzo yavo munyama mumuviri uye mune neitsvo.

"Allopurinol" mirayiridzo uchapupu

The mushonga ari ushandiswe:
yokudzivisa, kurapa gout uye hyperuricemia (kusanganisira kuoma renal kukundikana) chirwere nephrolithiasis ,, urate nephropathy;
pamwe karusiyamu oxalate itsvo mabwe akabatana hyperuricosuria;
panguva yakakwirira urate pamwero, aumba somugumisiro enzymatic zvirwere;
nokuti kudzivirira rikwanise nephropathy panguva cytostatic, nemwaranzi pakurapa bundu uye neleukemia;
kana kurapwa nzara.

"Allopurinol" mirayiridzo iri dosing

Chiremba anogadza dose zvinodhaka nomunhu zvichienderana
urate pamwero dzakaonekwa muropa uye weti, uyewo pamusoro wevasungwa ose uric acid. Adults kugadza 100 MG "Allopurinol" kusvika 900 MG pazuva. The daily dose kunodiwa kuti ive 2-4 mishonga. Mahwendefa zvinofanira kutorwa pashure kudya.
Vana vari pasi pemakore 15 dose daily dzaona zvakarurama maererano nzira: 10-20 MG pa 1 kg muviri uremu ane mwana kana achiita 100 MG "Allopurinol" kusvika 400 MG.

The kunonyanyisa dose varwere vane vasingadzoreki itsvo basa iri 100 MG. Chiremba kungawedzera dose kana pakanyorwa kurapwa inoramba kuzochinja mukuru pamwero urate inowanikwa ropa uye weti.

"Allopurinol" mutungamiriri nemishonga

Mune zvisingawanzoitiki Muzviitiko, takaona hadzina kufambiswa zvakanaka munyika kumwoyo, iyo akaratidza neBP, bradycardia.
Possible hadzina kufambiswa zvakanaka munyika zvomudumbu ino izvo zvinoratidzwa:
kuda kurutsa, kurutsa, manyoka, zvinopfuura kuwedzera transaminases akaona serum;
chiropa, chiropa dysfunction;
stomatitis (mu varwere nomumwe);
steatorrhea.

In kwadzo Muzviitiko "Allopurinol" mushonga kwakaita zvinetso munyika tsinga, izvo zvinoratidzwa:
simba, kurukutika, kutemwa nomusoro, dzungu;
ataxia, nehope, kuora mwoyo;
chaanoziva, paresis, paresthesia;
chinyamunhari chinorwadza, neuropathy;
kutadza kuona zvakanaka; tsanga;
zvachinja nemamiriro optic papilla;
dysgeusia.
Very kashoma vaichengeta hadzina kufambiswa zvakanaka munyika hematopoietic ino kuti kunoratidzwa thrombocytopenia, agranulocytosis uye aplastic kupererwa, leukopenia (boka pangozi rinosanganisira varwere vava renal shanda).

Possible hadzina kufambiswa zvakanaka munyika Urinary ino, izvo mashoma interstitial nephritis; Varwere nomumwe - edema, uremia, hematuria.

Mhirizhonga munyika kwemakemikari anobudiswa mugadziriro rwakavapo zvisingawanzoitiki zviitiko, kushaya mbereko, kusabetsera, gynecomastia, chirwere cheshuga.
Metabolic zvirwere richiratidzwa Kashoma hyperlipidemia.
Sema kana dermatological nenjodzi.

"Allopurinol" mirayiridzo contraindications

Hazvibviri taurira mushonga:
mune kusagadzikana chiropa, itsvo;
Pamuviri uye lactation;
pakuparwa hypersensitivity kuti "Allopurinol".

In kurapwa tsika, vana pazasi makore 12, "Allopurinol" ushandiswe bedzi pakurapa nyanyisa namamota, muna neleukemia, apo enzayemu zvirwere, zvakadai Lesch-Nihena syndrome.