Zviratidzo uye mabatiro kweserotonin chirwere

The unopinza kuwedzera huwandu kweserotonin - munhu nani chakakomba ezvinhu, icho pamwe uremu yokutyora mubasa yose muviri. Kazhinji, kuchinja izvi dzinokonzerwa kutora zvimwe zvinodhaka kana ovhadhozi nezvinodhaka siyana. Pasina nenguva kurapwa izvi hwakazara ngozi, dzimwe nguva kusingarapiki yakaipa. naizvozvo zvakafanira kuti funga mashoko pamusoro chii chinokonzera uye zviratidzo kweserotonin syndrome. Chii kurapa vanogona kupa mushonga ano uye zvikuru hwakazara nokushaiwa pakurapwa?

Kweserotonin chirwere: chii?

Kutaura zvazviri, mashoko okutanga pamusoro wehurumende ichi akaonekwa asina kudaro kare. Muna 1960 muUnited States zveBhaibheri okutanga dzakabudiswa nezvenyaya iyi. Chokwadi chokuti zvinokonzera kuti urwere, izvo, chokwadi, achiperekedzwa unopinza kuwedzera nhamba yemabhuku pafuma ari mumasero etsinga, pakawanda, pamwe antidepressants.

Zvinozivikanwa kuti kweserotonin Deficiency Syndrome inotungamirira kukura mwoyo. Uye muzana remakore rapfuura zvakanzi yagadzirwa mushonga kutyorwa zvakadaro, yava kunzi "antidepressants". zvinodhaka izvi kubatsira kuwedzera pamwero kweserotonin, anozivikanwa dzakakurumbira sezvo "mufaro kemikari". Under kwavo simba, chisingaperi kuneta uye kusakendenga zvishoma zvapfuura, uye vanhu zvishoma nezvishoma vodzokera dzose upenyu. Zvisinei, zvakare yakawanda kweserotonin anoita somunhu toxin, tigume masero etsinga, zvichikonzera uremu chirwere iri muviri. A yakafanana chirwere angava somugumisiro antidepressants, uye mubatanidzwa antidepressants uye zvimwe zvinodhaka (semuenzaniso, vamwe chikosoro syrups uye zvichingodaro. D.).

Kutaura zvazviri, munyika yanhasi, zviitiko kweserotonin chirwere zvinonyorwa kudaro kakawanda. Asi, maererano vanachiremba uye nevaongorori, zvinoitika chete nokuti chirwere yakazonyorwa semurwi imperceptible zviratidzo, izvo kazhinji mhosva pamusoro tsinga kunototiomesera kana kuneta. Naizvozvo zvakakodzera kuti kuziva nei kweserotonin chirwere zvingaitika, chii uye chii nezviratidzo zvaitevera.

The chikuru mabasa kweserotonin

Zvakakodzera kuziva mashandiro chiito kuti "mufaro kemikari", usati wafunga mubvunzo sei uye nei kusimukira kweserotonin syndrome. Chii zvinhu ichi? The chikuru basa ndiro murau kweserotonin mashandiro mune dzimwe Tutsinga tunofambisa mashoko utwu muuropi. Achipfuura synaptic mumukaha kubva dzouropi, fuma iyi zvaanoita zvimwe receptors vari Kamudzira iri pedyo etsinga sero, simba uye vachiridzira tsinga zvatinganzwa.

Kune akawanda hurongwa anogona waidzora uwandu kweserotonin pamuviri. Zvikurukuru, reuptake ichi, sezvamakaropafadzwa morekuru anodzokera dzinoona dzouropi wokutanga (sezvineiwo, antidepressants vazhinji FIs kweserotonin reuptake) uye enzymatic murau, umo chaiwo vanoshingaira fuma nokumunamatira kemikari Morekuru.

Kweserotonin inodzora pezvakaitwa zhinji pamuviri, kusanganisira:

• nguva hope uye takamuka;
• havi;
• budiriro kana kunyangarika kunzwa svoto;
• dzepabonde;
• thermoregulatory zvigadziriswe;
• omumwe marwadzo;
• Kutsigirwa tsandanyama inzwi;
• motility of zvomudumbu turakiti;
• murau pamusoro vascular matauriro;
• Rakaratidza kuti kweserotonin zvinobatanidzwa munyaya zvigadziriswe pakati migraine.

Sezvinogona kuoneka, "mahormone anofara" anopa womunhu muviri hausi chete kunzwa euphoria. Pashure pokudzidza mashandiro fuma ichi, zvinokwanisika kuti kufungidzira zvimwe zviratidzo kweserotonin syndrome. Nenzira, kufadza vakachengeta wevasungwa kemikari inonzi muuropi hunde uye reticular inotungamirwa.

Kweserotonin chirwere: nemakemikari omuviri. Chii chaigona pave nekukurukurirana kukanganisa?

Sezvambotaurwa, kutyora ichi, vakawanda yakatanga apo uchirapwa nemimwe mishonga, kana mubatanidzwa kwayo. Saka chii zvinodhaka kungamutsawo kukura kwezvirwere ngozi zvakadai kweserotonin chirwere?

• "Tsipraleks" uye dzimwe chakaita zvokugadzirwa kweserotonin reuptake FIs uye monoamine oxidase.
• Mawa kurapwa pamwe monoamine oxidase FIs uye thyroid mahormone, "clomipramine", "carbamazepine", "imipramine" uye "Amitriptyline".
• Mao FIs uye mubatanidzwa nezvimwe zvinodhaka zvinoshandiswa uremu, zvikurukuru "Dezopimona", "fepranona".
• Tikafunga ane SSRI kana Mao FIs kugadzirira ine L-tryptophan, St. vaJohani sana mushoma uye kufarisisa.
• Tikafunga lithium pamwe antidepressant zvinodhaka, kunyanya "Kontemnola" uye "Kviloniuma".
• Mawa negashiro FIs uye dextromethorphan (a fuma yakawanikwa zhinji chikosoro syrups, kusanganisira "Kaffetin Cold", "Glikodin", "Tussin Plus" nevamwe.
• Tikafunga kweserotonin reuptake FIs zvinodhaka akadai "dihydroergotamine", "sumatriptan" (migraine zvinodhaka), "Levodopa" (yaishandiswa Parkinson chirwere).
• Pane uchapupu hwokuti kweserotonin chirwere chinogona kuitika nokushandiswa doro pakanyorwa antidepressant mishonga.

Pakarepo zvakakodzera shoko kuti kufanotaura kana kukudziridza chirwere pamusoro pakanyorwa yachiremba kugadzwa kurapa, kutonetsa. Zvose zvinoenderana dose mishonga, munhu zvechadenga murwere, zera rake uye zvimwewo zvakawanda. Zvisinei, kana uri ushandiswe antidepressants, iva nechokwadi iwe udza chiremba wako pamusoro zvose mishonga yamuri kutora uye kuva nechokwadi kuti kubvunza pamusoro pakatanga idzva Zano yokurapa, kana kunyange zvakajairika chikosoro manyuchi.

The chikuru zvechadenga zvekuchipatara mufananidzo

Ko kweserotonin chirwere? Zviratidzo hafu nyaya kuonekwa mushure maawa 2-4 mushure ingestion. Asi zviratidzo vokutanga kuonekwe uye zuva. Nezvokumutswa huru mashandiro kweserotonin, zvose kutyorwa zvinobvira vanokamurwa muzvikwata mikuru mitatu:

• chirwere chepfungwa;
• kubva tsandanyama matambudziko uye peripheral huta nehurongwa;
• autonomic zvirwere.

Zvose zvinoita zviratidzo zvinotsanangurwa pazasi, asi kutanga zvinofanira kutaurwa kuti infringements siyana hazvisi chakaparadzana panobva Pfungwa ose chirwere chakadai. Chete zvakakwana wenyama kuongororwa, rabhoritari zvidzidzo, uye mune zvimwe zviratidzo uye zvichiita zvinokonzera njodzi kuti tikwanise kuziva zvakawandisa kweserotonin iri etsinga dzomuviri.

Chepfungwa pahwaro ari urwere

Sei kuziva kweserotonin chirwere? Zviratidzo kazhinji kutanga chirwere chepfungwa, kusanganisira:

• mupfungwa asina kuzvironga;
• hazvitaurwi, causeless kutya uye kuzvidya mwoyo, dzimwe nguva kusvika vhunduka;
• dzimwe nguva pane mumwe mufananidzo - munhu anonzwa pfungwa euphoria, mufaro kwazvo, chido kutama, taura muchinyengetera uye kuita chimwe chinhu pamusoro pazvo;
• zvinogoneka vanotaura kuti pfungwa;
• Muzviitiko zvakaipisisa, pane chitarisiko zvinovadadira uye fungidziro.

Zvinokosha kucherechedza kuti zviratidzo uye ukuru zvakaoma iri zvakananga novimba kwokuomerwa ari chepfu migumisiro. Somuenzaniso, dzimwe nguva chete zvishomanana excitation iri kuchengetwa. Mune zvimwe zviitiko pane kuwedzera nezviratidzo chaicho chirwere (semuenzaniso, kuora mwoyo), nokuda iyo mishonga iri mberi. In wakakura zvikuru kacho, murwere anotambura nekuvhiri- ngika, kuvhiringidzika munyika uye kuzvida, nechirwere zvinovadadira uye fungidziro siyana.

Huru vegetative zviratidzo

Pane zvimwe zviratidzo pematanho kweserotonin syndrome. Damage kubva unopinza kuwedzera padanho fuma iyi vangatarira mumwe nzira. Kunyanya, akacherechedza uye autonomic zvinetso, kusanganisira zvinotevera:

• dilated vadzidzi, uye akawedzera lacrimation;
• wedzera mumwoyo zvazvingava, tachycardia;
• kuwedzera respiratoria;
• dzimwe nguva pane fivha (kazhinji, iduku, asi hwakanyorwa fivha rworwendo 42 mune vamwe varwere);
• rakapinza kuwedzera BP ne concomitant zviratidzo kusvikira nokurasikirwa pfungwa;
• pakuonekwa kuoma mumuromo uye pane vamwe mucous membranes;
• kuwedzera gastrointestinal motility, izvo zvinozoita kungaita kuti zvinetso zvakadai semanyoka, zvikuru kuda kurutsa uye kurutsa, flatulence, bloating uye abdominal marwadzo kunosiyana nekuomarara;
• kunzwa chill;
• Nomusoro, dzimwe nguva kutemwa nemusoro.

Sezvaunogona kuona, zviratidzo chirwere ichi vari kunyanya zvakananga, nekuti zvakafanana zviratidzo angaperekedzwa zvimwe zvirwere gumi nevaviri.

Neuromuscular nepfungwa iri pakanyorwa urwere

Sezvambotaurwa, kweserotonin anoita nokupfuuridzirwa etsinga nomunhu. Ndokusaka nokuchinja padanho fuma iyi kunokanganisa neuromuscular basa. Heino mazita zvichibvira zvirwere:

• kwakawedzerwa pane mudzira hunenge (kunyanya kutaurwa vari nechepazasi muzvidimbu hunenge);
• uvandudze kuti tsandanyama matauriro uye dzimwe nguva kusvika tsandanyama Rigidity;
• nokukurumidza uye involuntary spasmodic marwadzo ose (dzimwe nguva kunyange mapoka yose tsandanyama) nomumwe tsandanyama;
• vachibvunda maoko nemakumbo;
• involuntary fambisa yeziso (nokuti chinangwa ichi mukurapa okuti "nystagmus" rinoshandiswa);
• dzimwe nguva pane inonzi ziso spasm, izvo pamwe ne involuntary rinopfungaira pakati eyeballs kumusoro kana pasi;
• nguva yakanyorwa pfari;
• kushaya Kufambisa;
• matambudziko nokutaura kuti avhiringidzwa uye inaccuracy kuti kunoitika nokuda ari involuntary marwadzo tsandanyama ose nekunyatsotsanangura midziyo.

Zvinonzi kunzwisisa kuti zvose pamusoro zviratidzo kweserotonin chirwere kuitika kazhinji. Kazhinji, varwere vanotambura chete kubva vamwe kutyorwa, uye saka chirwere zvirwere zvakasiyana munhu yainetsa kwacho.

The mwero chirwere nekuomarara

In mushonga ano rakakamurwa madhigirii matatu kwokuomerwa ari urwere, yakadai se:

• Munyoro chirwere achabatsirwa, sezvinoita mutemo, wakawedzera vangadikitira, kwete simba tremor mumaoko nemabvi, kunyanya raidudzwa kuwedzera kwemwoyo. Hunenge kuva zvishoma kwazvo, kunyange zvazvo tembiricha muviri rukasafashukira. Dzimwe murwere ungacherechedza mboni dilation. Zviri muropa kuti vanhu zvakafanana zviratidzo kashoma kuenda kwachiremba, uye kuramba zvinodhaka, nokuti pamusoro zviratidzo zvinogona kukonzerwa kushushikana kana overexertion.
• In zvine mwero kunotoda mufananidzo chirwere zvikuru raidudzwa. Varwere akaona nomusiyano kuwedzera tembiricha muviri (dzimwe nguva kusvika 40 madhigirii), uye BP, kuramba dilation pakati vadzidzi, kuti rutapudzo pakati tsandanyama, injini uye mafaro mupfungwa. Kazhinji, zviratidzo izvi kuti munhu kutsvaka rubatsiro, asi zvinosuruvarisa kuti kuisa zvakarurama zvokuongorora hazvibviri nguva dzose.
• Zvakakomba kweserotonin chirwere ngozi kwazvo, sezvo kungaguma matambudziko. In chimiro ichi zvokurwara akaona simba tachycardia, wakawedzera BP, fivha, kwetsandanyama kusvikira kuomarara, huta zvirwere, nekuvhiri- ngika. Varwere kazhinji kuwana fungidziro yakajeka zvikuru. Pasina rubatsiro nenguva anogona zvakakuvadza tsandanyama, chiropa uye itsvo. Kazhinji, varwere vanowira pakoma. Apo neapo dzakabudirira vakawanda nhengo kukundikana, izvo kazhinji kunoguma murufu.

Ndokusaka kuzvidzosera hakufaniri kufuratira zviratidzo nokuti anogona anoedzesera kuva zvisingatomboiti kweserotonin chirwere zvakapfurikidza. How kubuda ehurumende ichi, uye kana pane dzinobudirira kurapa?

rubatsiro rwekutanga mukurapa mamiriro ichi

Zvakadini kana munhu vanofungidzirwa kweserotonin chirwere? Emergency kuchengetwa kakawanda chinhu nokukurumidza kumbomira zvinodhaka, izvo akaparirwa ichi. Sezvingatarisirwa, unofanira zvachose kutora murwere kuchipatara.

Kutanga gastric lavage, achiita zvichiita kuti vanatse muviri mumwe mushonga kuti haasati aiva nguva nyura. Tiine chinangwa ichocho, varwere ushandiswe zvinodhaka nezvimwe sorbents deducing zvinokachidza kubva mumuviri. In nyoro Muzviitiko zviitiko zvakadaro zvakakwana kuti vanhu vanzwe zviri nani. Zviratidzo zviri pasi pashure maawa 6-12.

Sei pakurapa chirwere?

Zvinosuruvarisa zvinodhaka kurega uye kunatsa muviri kubva Marara haasi nguva dzose kukwana. Saka chii kurapa zvinoda kweserotonin chirwere? Kurapwa Chokwadi, kunoenderana pachikuva nekuomarara. Kazhinji, murwere akagadza kweserotonin Kanotokonya mhandu, kusanganisira "methysergide" uye "Cyproheptadine". Uyezve, kuva symptomatic kurapa, izvo kunoenderana pamberi zvimwe zvirwere.

• Somuenzaniso, mune zvipusha pfari uye tsandanyama Rigidity varayire benzodiazepines, kusanganisira "lorazepam" uye "Sibazon".
• In pamberi fivha yaitwa chando rubdown uye dzimwe nzira dzokurapa. Chokwadi kuti kuwedzera kupisa kana kweserotonin chirwere haina chokuita kuzvimba, uye pamwe yakawedzera tsandanyama contractility, uye nekuti kwakajairika antipyretic uye nonsteroidal Anti-anogumbura zvinodhaka zvisina maturo. The chete kunze ndiko paracetamol, kunyange rinofanira kushandiswa nokungwarira.
• Apo tembiricha inokwira kusvika 40 uye zvakawanda tsandanyama relaxants vari raitongwa murwere. zvinodhaka izvi kubatsira kuzorora tsandanyama, kubvisa fivha, kudzivisa kutanga zvinetso zvakasiyana-siyana, kusanganisira nezvinetso kweropa.
• Uyewo intravenous aizomupa inoitwa sezvo kunyanya vangadikitira, manyoka, tsandanyama kunetsana uye kutungamirira kupera mvura mumuviri.
• Uyezve, zvinokosha kuti akuteerere BP uye mwoyo yevanhu murwere, kana zvakafanira normaliziruya manhamba izvi achibatsirwa zvinodhaka.

Kazhinji, zvakanaka kuitwa kurapa kunogona nokukurumidza kuvandudza mamiriro murwere uye kudzivisa migumisiro. Zvinosuruvarisa muna zvisingawanzoitiki zviitiko, kunyanya kana murwere asina akapa yakakodzera mishonga, kweserotonin chirwere kungaita kuti disintegration yacho tsandanyama rinenge chiropa uye kukuvara itsvo, tsinga harinzwi uye pakupedzisira rufu. Ndokusaka kuzvidzosera hakufaniri kurerutswa kutora antidepressants uye zvimwe zvinodhaka.