The mushonga 'Warfarin'. Mirayiridzo yokushandisa

The mushonga "Warfarin" mirayiridzo yokushandisa rinoreva chikamu anticoagulants ose kunanga chiito. The mushonga anokwanisa tunodzivisa kwetunhu pakugwamba zvinhu (vhitamini K-zvaanoda) uyewo mapuroteni C uye S iri chiropa. Zvakanyanya Kunaka Panguva Yepamuviri anticoagulant maturo aona pazuva rechitatu kana rechishanu zuva pashure mharuro kurapwa uye agumisa pashure matatu namashanu mazuva pashure rokupedzisira dose. The mushonga inowanika piritsi fomu.

Zvinokurudzirwa apo kutora mushonga "Warfarin" Kudya kunosanganisira kuramba zvinenge zvakafanana vhitamini K ari kudya

umboo

The mushonga inoratidzwa kuti kudzivirirwa uye Mabatirwo thrombosis uye thromboembolism. By zvairatidza kuti zvinodhaka "Warfarin" mirayiridzo Chinyorwa inorondedzera thromboembolism uye rikwanise venous thrombosis, pulmonary embolism, dzokororo ine myocardial infarction, postoperative thrombosis. Kugadzirira iri nachiremba pakutevedzera thromboembolic kubviswa kana kuvhiya thrombosis (sezvi- nzira) kuti atrial fibrillation (magetsi cardioversion), relapsing (re) tsinga thrombosis, embolism ari pulmonary tsinga. Rinoreva "Warfarin" mirayiridzo Chinyorwa anokurudzira ari vascular prosthetics uye mwoyo mavharuvhu (ndiko akabvumira nokushandiswa mubatanidzwa wenyika acetylsalicylic acid). Uyezve, mushonga wacho nachiremba thrombosis, chepfungwa, coronary uye peripheral arteries, uyewo yechipiri kudzivirira thrombosis kana embolism panguva nekubwaira ane atrial kana pashure infarction.

Contraindications kuti mushonga "Warfarin" mirayiridzo Chinyorwa classifies nomumwe kusashivirira, renal kana hepatic chirwere zvakakomba, rikwanise ropa, BP (rinorema hunhu), exacerbation nemaronda mudumbu kana duodenum, Hemorrhagic diathesis, kushaya S uye C mapuroteni, kudhakwa, chepfungwa ropa, renal basa insufficiency, chenjera DIC, thrombocytopenia. Gadzai mushonga panguva yepamuviri.

Rakajairika yaivhuvhuta zviitiko panguva yaitonga zvinodhaka "Warfarin" riri ropa. Mune zvisingawanzoitiki kacho pane necrosis ganda, ikawanda chiropa makemikari, manyoka, eczema, bvudzi kurasikirwa, vasculitis.

chipimo chemushonga

The mushonga zvinoratidzwa nekuda nomumukanwa yaitonga. Varumbidzwa chete chikumbiro, panguva iyoyo. The kwokutanga dose - maviri nehafu kuti milligrams shanu pazuva.

Tevera dosing zvaiitwa "Warfarin" (INR kana prothrombin nguva apo izvi kufungwa) akatsunga nomumwe. Napakati mana nguva kubva kupi kunofanira akawedzera prothrombin nguva. Panyaya iyi INR (International normalized reshiyo) inofanira kusvika (zvichienderana zvokurwara mukana kuti ropa, thrombosis ngozi) 2.2-4.4.

Varwere vakwegura kana mune simba ezvinhu ushandiswe dzakaderera mishonga yacho zvinodhaka "Warfarin".

Usati wataura mashandiro (panyaya kubatwa kukudziri- thromboembolic yematambudziko) kurapa kunotanga mazuva maviri kana matatu asati kupindira.

In chenjera thrombosis kurapwa rinoitwa Rakabatanidzwa zvinodhaka "Heparin" kusvikira nhambo apo anticoagulant kwepasi haina zvakazara richiratidzwa (kakawanda kwete pamberi rechitatu uye reshanu).

Ya yokurapa kunobva murwere ezvinhu.

kutanga kurapwa Asati zvaanofanira kuona imwe INR indekisi (maererano prothrombin nguva, akapiwa wanda coefficient thromboplastin).

Maererano varwere vakawanda, mishonga "Warfarin" harisi chete inoshanda, asi nyore, sezvo anofanira kutorwa kamwe pazuva chete. Uyezve, zvinoreva kwazvo akashivirira, nemishonga hadziwanzowaniki. Zvisinei, asati kushandisa chigadzirwa, unofanira kubvunza nyanzvi, uye verenga nokungwarira mirayiridzo.