The mushonga "Sporagal": mirayiridzo kushandiswa, analogs uye wongororo

Sei kutora zvinodhaka "Sporagal"? Mirayiridzo kushandisa zvinodhaka ichakurukurwa mberi. Uchadzidzawo kana pane analogues rokugadzirira ichi, sei tinorasikirwa, uti pamusoro pake varwere, nokuti chii chinangwa kwakanyorwa chinotarisirwa, uye zvichingodaro. D.

Form, akafanana, kavha antifungal zvinodhaka

Kugadzirira "Sporagal" rinowanika Kamudzira fomu. Its chikuru achishingaira chirungiso iri itraconazole. Uyewo medicament unotora polyethylene glycol 20000, sucrose, uye hydroxypropyl acrylate copolymer.

Panyaya goko, izvozvo rinoumbwa gelatin, titanium yakasviba uye indigotin.

In pasuru chakatengeswa mushonga "Sporagal"? Mirayiridzo vachishandisa nzira iyi midzi ari makadhibhokisi bhokisi. Rinewo zvakaoma gelatin Kamudzira rutema (mu Maronda akasiyana), izvo vane idenderedzwa granules yellow ruvara.

Pharmacodynamics medicament

"Sporagal" piritsi sei? Maererano mirayiridzo, mushonga rinobva triazole. It ane yakakwirira basa pamusoro notumwe.

The mushonga kunobatsira kuderedza zvipenyu kwetunhu ergosterol, ichipa ane antifungal kushanda.

Nyanzvi dzinoti itraconazole kuchititadzisa kukura uye kubereka vana kuwanda mhando notumwe.

The pharmacokinetics pamusoro antifungal mumiririri

Drug "Sporagal", iro analogues achaiswa wainyatsotaura mberi, vakakurumidza wefodya unopinda muropa. The soro pamwero itraconazole muvanhu iri kuchengetwa pashure maawa 3. bioavailability Its ndiyo 55% (kufadza iri kwakacherechedzwa pamabiko capsules pakarepo kutevera kunwa ane mafuta uye mukuru-mafuta zvokudya).

Itraconazole ari kukamurirwa zvakasiyana nhengo uye nyama dzomuviri. kugutsikana yaro mapfupa, itsvo, chitaka, mapapu, skeletal tsandanyama, dumbu, chirwatata uye ka3 kupfuura muropa.

Medicament rinoita ari chiropa kusunungura munhu muzvizhinji kuti nomukaka. Zvisinei, chete gidroksiitrakonazol ane anzi antifungal kushanda.

Inenge 34% yezviri fuma iri kusunungurwa weti, uye vanenge 54% kubudikidza ura.

In vanhu ane vasingadzoreki chiropa nerevane cheitsvo, uye vari varwere immunosuppression bioavailability zvinodhaka kunogona kuderedzwa.

zvairatidza capsules

Sei kugadza "Sporagal"? Instruction inoti kuti mushonga wacho akaronga kuti pakurapa fungal zvirwere, dzakanga kushatiriswa zvinodhaka utetsa utachiona:

• vulvovaginal candidiasis;
• ophthalmological uye dermatological kusagadzikana fungal kupi (semuenzaniso, fungal keratitis, chisasa, pityriasis versicolor);
• nomumukanwa candidiasis ;
• onychomycosis, vakanga kushatiriswa dermatophytes kana yeasts;
• systemic mycoses kusanganisira cryptococcosis (vanhu simba rokuzvidzivirira panguva tsinga cryptococcosis medicament raitongwa chete pasina kurapwa migumisiro dzimwe antifungal vamiririri), cryptococcal yomumuzongoza, systemic aspergillosis uye candidiasis;
• sporotrichosis, paracoccidioidomycosis, blastomycosis, histoplasmosis, uye mamwe mashoma systemic mycoses.

Contraindications pakushandisa capsules

Ndezvipi contraindications kuti kushandisa zvinodhaka "Sporagal" (Mahwendefa)? Instruction inoti kuti mushonga irege kushandiswa:

• Hypersensitivity kune nesekondari zvinoumba mushonga
• pachiimbwa mishonga yakadai se "Eletriptan" blockers HMG-CoA reductase FIs (semuenzaniso, "atorvastatin", "Lovastatin" "simvastatin"), ergot alkaloids, substrates CYP3A4 (somuenzaniso, "Cisapride", "bepridil," "pimozide" "Dofetilide", "Astemizole" "quinidine" "mizolastine"), "nisoldipine," "Midazolam", "triazolam".

Zvinofanira kucherechedzwa kuti kushandisa zvinodhaka izvi contraindicated vanhu vane ventricular dysfunction uye mwoyo nokukundikana, kunyanya congestive hunhu.

Drug "Sporagal": mirayiridzo kushandiswa

Maererano mirayiridzo, mushonga unofanira chete kutorwa nomuromo. The capsules apere pakarepo pashure zvokudya (kuitira Absorção de Água nani), iri yose, pasina kutsenga.

The chipimo chemushonga mishonga iyi kunoenderana norudzi yaivapo chirwere:

• Dermatological uye ophthalmologic lesion (semuenzaniso, pityriasis versicolor kana chisasa) - 200 MG kamwe pazuva kwevhiki.
• Keratinized maronda ganda (maoko nemakumbo) - 200 MG kaviri pazuva kwevhiki.
• Vulvovaginal candidiasis - 200 MG kaviri pazuva kwemazuva matatu.
• Oral candidiasis - 100 MG kamwe pazuva kwevhiki mbiri. In varwere AIDS kana neutropenia, dose yakawedzera kusvika 200 MG kamwe pazuva.
• Fungal keratitis - 200 MG kamwe pazuva kwevhiki nhatu.
• Onychomycosis, vakanga kunokonzerwa dermatophytes kana yeasts, vari kurapwa pachishandiswa inodzokororwa mapoka. Mumwe mushonga kunosanganisira kutora capsules maviri kaviri pazuva kwevhiki. Nokuti kurapa ezvipikiri maronda pamusoro minwe rinoitwa 2 yamabwe yokurapa ichi, uye netsoka - 3 mapoka. The zororo pakati zviviri zvinofanira kuva 3 mavhiki. Kuvhiringidzwa kunoratidzwa mushure kosi kupera (pamwe nezvokukura ezvipikiri kwamahwendefa).

gadziriro kubvisa "Sporagal" pamusoro chipikiri uye ganda rinoitwa kuti yakareba kupfuura kubva ropa. Panyaya iyi, Zvakanyanya Kunaka Panguva Yepamuviri kuchirapa migumisiro varwere vari kubudirira mavhiki chete pashure nhatu pashure pokupedza yokurapa kutapukirwa uye inenge 9 months pashure nokurapa onychomycosis.

Nzira Kushandisa capsules kuti systemic maronda

Sezvo systemic maronda kutakura kushanda? "Sporagal" kunan'anura zvinotevera dosages:

• Candidiasis - 100-200 MG kamwe zuva nezuva kwemavhiki 5-30.
• Cryptococcosis pasina yomumuzongoza - 200 MG pazuva nokuda 3-12 mwedzi. With kaviri dose yomumuzongoza.
• Aspergillosis - 200 MG pazuva nokuda 3-5 mwedzi.
• Histoplasmosis - 200 MG kaviri pazuva kwemwedzi misere.
• Chromomycosis - 100-200 MG pazuva kwemwedzi mitanhatu.
• Sporotrichosis - 100 MG pazuva kwemwedzi mitatu.
• Paracoccidioidomycosis - 100 MG zuva kwemwedzi mitanhatu. Varwere AIDS, kuti chipimo chemushonga anogona ngazviwedzerwe.
• Blastomycosis - 100-200 MG kaviri pazuva kwemwedzi mitanhatu.

Side anokonzerwa nemishonga

Pane divi migumisiro Varwere pakugamuchira "Sporagal" chinodhaka? Reviews nenyanzvi rakashuma zvinotevera siyana:

• neutropenia, thrombocytopenia, leukopenia;
• kufema turakiti Zvirwere (yokumusoro);
• hypertriglyceridemia, hypokalemia, hypocalcemia;
• nemusoro, paresthesia, peripheral neuropathy, hypoesthesia, dzungu;
• serum kurwara, angioneurotic edema, anaphylactic uye anaphylactoid neutachiona;
• madzerere, diplopia, kusanzwa, tinnitus, madzerere;
• mwoyo kukundikana, kunyanya congestive hunhu;
• dyspnea, rhinitis, sinusitis, pulmonary edema;
• kurutsa, dyspepsia, hepatotoxic siyana, abdominal marwadzo, pfungwa nomuviri zvemwana asati, kuda kurutsa, dysgeusia, kupatira, hepatitis, manyoka, bloating, kwenguva pakukwirira chiropa transaminases;
• marwadzo ari mapfundo tsandanyama;
• mapundu, photosensitivity, leukocytoclastic vasculitis, alopecia, chepfu epidermal necrolysis, pruritus, exfoliative dermatitis, mapundu, chenjera generalized exanthematous pustulosis, erythema multiforme;
• dysmenorrhea, Urinary incontinence, erectile dysfunction, pollakiuria;
• fivhiri, edema.

chaizvo kurumbidza

Zvaunofanira kuziva murwere, asati atora zvinodhaka "Sporagal"? Mhinduro akashuma kuti chacho vanoshingaira fuma ine kunaka inotropic kushanda.

Nepo kutora mushonga uyu anogona kuva congestive mwoyo kukundikana, uye zvikuru hepatotoxicity.

Kana akaderedza acidity zvinodhaka absorbability kuipa.

Vanhu panguva kushandisa antacids zvinofanira kuchengetedzwa pakati pavo uye nzira kugadzirira vanorondedzerwa penguva 2 maawa.

Drug "Sporagal" kwete pachii varwere vakwegura.

Kana uine zviratidzo peripheral neuropathy paakatora nemishonga kudzima.

Achiyamwa uye pamuviri

Panguva pamuviri, mishonga anogona kupiwa bedzi systemic mycoses, izvo kurwisa waamai upenyu.

Kana achiyamwa, iyi, "Sporagal" Unotenderwa, asi chete pasi oma zvairatidza.

Drug "Sporagal": analogs uye mutengo

Zvinotevera zvishandiso ndivo analogues kupfuura kuzivikanwa zvinodhaka pasi kukurukurwa, "Itrungar", "Sporaksol", "Orungal", "Eszol" uye "Funit".

How kuzhinji chinodhaka "Sporagal"? Mutengo mishonga iyi kunosiyana-siyana pakati 1100-1200 rubles.

Reviews kugadzirira

Maererano inofambiswa vaya akatora chinodhaka, zvinogona kucherechedzwa kuti zviri zvikuru kunobudirira kunooneka pacharo mune mhando dzakasiyana-siyana fungal zvirwere. inogona kure akaipa mashoko avo vanoti chokushandisa ichi ane kudhura. Zvisinei, vanamazvikokota vanoti mutengo zvinodhaka ichi unoruramiswa zvachose ayo kuchirapa efficacy.

Kana zvazvakashatira zvinodhaka ichi, varwere kazhinji kutaura pfupi yakareba kurapwa.