The mushonga "Merkazolil" mirayiridzo

The mushonga paanouya piritsi fomu. Pharmacological chiito kwakavakirwa
antithyroid ehupfumi yezviri fuma - methimazole (5 MG muna 1 piritsi). Medicine "Merkazolil", akaongororazve vanachiremba ngaadarowo kuchititadzisa ari enzayemu peroxidase, izvo hazvibviri pasina maitiro iodization kuti thyroid mahormone vari thyroid shwanu. Zvinoguma nyonganyonga yacho inotungamirwa kurapwa thyroxine uye triiodothyronine.

Methimazole zvakanaka woga kubva nemudumbu. The hafu-upenyu huri maawa 6. It rinoita mumuviri, zvinoita panobviswa nokuda itsvo zvachose.

The mushonga "Merkazolil" mirayiridzo

The mushonga ari ushandiswe:

• panguva tireotoksicheskom Kurohwa ;
• mu diffuse chepfu goiter;
• pasi yakavhenganiswa hunokachidza goiter iri kunzwisisa kurapwa pamwe thyroid hormone yomuchipatara kana radioactive ayodhini mishonga.

Medicine "Merkazolil": mirayiridzo kushandiswa

Chipimo chemushonga chiremba anosarudza nomumwe zvichienderana murwere ezvinhu. Yemanyorero ushandiswe 20 MG kusvika 40 MG pamusoro methimazole daily. Varumbidzwa daily dose muzvikamu 2-4 mishonga. Normalization kuti thyroid basa kwakacherechedzwa pashure kurapwa merkazolilom zvechigarire kubva 3-Eks kusvika 8 mavhiki. Mushure yakanaka vakawana murwere kune imwe Nokuraramisa Thiamazolum kurapa mune mishonga kubvira 2,5 MG 10 MG pazuva.

Kuchirapa daily dose kuti vana kubvira 1 kusvika 300 micrograms por makirogiramu kusvika 500 MG muzana 1 kg. Kutsigira daily dose vana runobva 1 kusvika 200 micrograms muzana makirogiramu kusvika 300 MG muzana 1 kg. Maintenance dose pamusoro methimazole raitongwa imwe-nguva, ari mangwanani pashure pokudya kwemangwanani.

Rinoreva "Merkazolil": nemishonga

Munguva kurapwa miedzo zvinodhaka vakanga vakachengeta kashoma neutachiona ari muchimiro mapundu kana fivhiri; Varwere nomumwe akashuma zviratidzo volchanochnopodobnogo syndrome.

Kutyorwa kuri hematopoietic ino hadziwanzowaniki leukopenia, agranulocytosis; zviratidzo generalized lymphadenopathy vakanga kuchengetwa varwere chete.

Hadzina kufambiswa zvakanaka munyika zvomudumbu ino hadziwanzowaniki Kuchinja kuravira; Varwere nomumwe akanga dzakaonekwa chiropa chirwere, achikurudzira kuti kurutsa uye svoto.

Mhirizhonga munyika tsinga iri kuvazivi chete Kashoma pachena neuritis uye polyneuritis, nomusoro.

Disruptions kuti kwemakemikari anobudiswa hurongwa akaratidza hyperplasia isiri yekenza yacho thyroid shwanu.

The mushonga "Merkazolil" mirayiridzo: contraindications

Hazvibviri taurira mushonga:

• kwazvo leukopenia kana granulocytopenia;
• hypersensitivity kuti methimazole;
• panguva pamuviri;
• lactation.

Side Migumisiro zvinodhaka "Merkazolil" vakadzi vane pamuviri vane ukama kukwanisa kwayo kuyambuka placental chipingamupinyi. Naizvozvo, kushandisa methimazole pashure I trimester hwakazara kukura hypothyroidism ari mudumbu.

Side Migumisiro zvinodhaka "Merkazolil" kuyamwisa vanamai imhaka kukwanisa kwayo dawo kupinda zamu mukaka.

Medicine "Merkazolil" Instruction: anokosha mirayiridzo

Thiamazolum kurapwa kunosanganisira kudikanwa nguva kuongorora ropa mufananidzo.

Treatment mikuru Strum Thyroid yakaoma constriction pamusoro trachea anofanira kuzviita zvishoma. Refu kunokwanisa kukonzera kukura Struma.

Iva nechokwadi kuti aite zano murwere asati kurapwa merkazolilom kutsanangura kukosha kuona chiremba nezviratidzo kunaka kuchinja hurumende yokutanga. Fivha ichi, zvikuru huro, kuzvimba mucous membranes mumuromo, pakuonekwa pamota - hwokufananidzira zviratidzo agranulocytosis.

At kuuya Kuvhiya kugadzwa Merkazolil chikwereti mavhiki 1-2. Kugadzirira strumectomy vakatakura zvinodhaka ayodhini-tune.

Zvakakosha kuyeuka kuti Kusava ayodhini mumuviri murwere kunowedzera nezvaizoitwa methimazole, uye ayodhini nekumwisa lowers nezvaizoitwa methimazole.