Drug "Sotageksal", analogs uye inofambiswa pavo

Arrhythmia - mufananidzo kwemwoyo, inova vakasiyana chakaipa sinus mutinhimira. Kana arrhythmias muvanhu uriko kana akawanda kutyorwa mwoyo. The zvokurwara anogona kupa ave kakawanda uye simba amplification kwemwoyo (tachycardia) uye, Ukuwo, vasanyanye dzavo (bradycardia). Disruptions kubasa mwoyo tsandanyama uye vane utano hwakanaka. Zvisinei, kazhinji, kuti arrhythmia riri pachiimbwa nezvimwe zvirwere cardiac. mamiriro akadaro ngozi pakuti excitability vakawedzera nomwoyo rinenge - myocardium, izvo zvingaita pakupedzisira kuti mwoyo kutadza kana kuruboshwe untreated.

pane chinokosha kugadzirira normalization nomwoyo zvazvingava, rimwe riri "Sotageksal". Analogues zvinodhaka rinoshandiswawo chaizvo okurapa. zvinodhaka izvi nhengo boka mishonga kuti vane antiarrhythmic basa, uye Beta-blockers. Kana anwa, ivo adzikatidza Beta-adrenergic receptors, izvo riri kumeso tsandanyama, cardiac tsandanyama uye mune dzimwe nzvimbo dzomuviri, uye vane basa muviri achipindura zvinokonzerwa mupfungwa. Kunopindirana kardioeffekt ndiko kuderedza kakawanda uye kusimba mwoyo zvazvingava, kunoderedza cardiac conduction. Somunhu systemic kushanda ari vakacherechedzawo richikwidibira ropa nevezera pamusoro pamasvingo coronary nhumbi.

mushonga

"Sotalol» (Sotalol) - nevamwe remarudzi zita munyika zvinodhaka "Sotageksal". Analogs pakati murwiyo angava antiarrhythmic zvakasiyana, asi ndozvinoitawo. Huru vanoshingaira fuma "Sotageksal" rine sotalol hydrochloride. Uyezve, chinosanganisira vashomanana upiyona zvinoriumba. Pakati pavo, - cellulose, lactose monohydrate, chibage starch, magnesium stearate nezvimwe binders.

The pasherefu upenyu mahwendefa kana injectable anogadzirisa 5 makore.

"Sotageksal" analogues Kuronga

Imwe pahwendefa chigadzirwa ichi rine 40, 80 kana 160 MG kuti basa fuma. Anogadzirwa ainyanya sezvo White rwakapoteredza mapiritsi chete divi zvishoma convex uye Mabhuku eBraille pamwe chidimbu SNA. On seri hwendefa iri bisected pachishandiswa dosing kuti zvivanakire kukuvara. All rakazara muna Maronda akasiyana zvezvimedu 10, uye mabhokisi makadhibhokisi. Mumwe tsapo Ingasiyana kubva 1 kusvika 10 Maronda akasiyana (inobva 10 kusvika 100 zvidimbu zvemahwendefa).

Uyewo, "Sotageksal" anogadzirwa muchimiro mhinduro kuti intravenous jekiseni. Mumwe ampoule rine 4 ml zvinodhaka. Muna 1 ml anogadzirisa 10 MG yakaisvonaka inokosha fuma. The mushonga inofanira kuchengetedzwa kubva chiedza chezuva yerima uye nzvimbo yakaoma, umo vana vawane ishoma.

Analogs pamwe yezviri fuma sotalol Mahwendefa hydrochloride anogadzirwa:

• "Sotaleks" (160 MG).
• "Soritmik" (by 0,16 g).
• "Sotalol Canon" (80 160 MG).
• "Darob" (80 160 MG).
• "Tenzol" (80 160 MG).

Pharmacological migumisiro

"Sotageksal" analogues anoreva zvakafanana zvinodhaka vane raidudzwa Anti-arrhythmic mugumisiro. Izvi zvakabatsira pamusaka kugona kwavo kuvhara β-adrenergic receptors uye tunodzivisa potassium makwara. Drugs kuwedzera nguva yose pulses uye dzepanguva nguva atria uye ventricles. Wedzerai mataurire Árbol anotsvedzerera tsandanyama uye tsandanyama rukoko ari mudziyo masvingo. Deredzai myocardial contractility.

Sotalol hydrochloride ane rose akagadzirwa zvivako. Ane kunaka chronotropic, dromotropic, batmotroponoe uye inotropic mugumisiro zvinodhaka German "Sotageksal". Analogs, murwiyo izvo zviri fanana, angava mumwe muchiso zita. Vanofanira achigonawo kuderedza kwemwoyo yavo simba. Nekuti vanoda ichi nokuda myocardial okisijeni manwiro ipfupi kwazvo. Uye somugumisiro, mutoro pamwoyo ipfupi.

Absorção de Água uye excretion zvinodhaka

Drug Absorção de Água iri nokukurumidza. bioavailability Its 90%, uye Absorção de Água - 80%. Mumaawa 2.5-4 pamusoro kunonyanyisa Kuwanda vanoshingaira chirungiso kunoitwa mushure mekugamuchira plasma. Mushure intravenous Kutarisirwa, mugumisiro ratova pachena pashure maminitsi 5-10. Absorção de Água ndepana 20% nani uye dzichimhanya kana iwe mushonga usina chawadya. Nokuti kuti solubility zviri pafuma ari mafuta yakaderera chaizvo, sotalol hydrochloride havafaniri kutorwa panguva imwe chete nomukaka zvinhu uye mafuta dzemhuka mavambo.

Pasina akasungwa kuna ropa mapuroteni, mushonga wacho richiparadzirwa munyama uye peripheral zvomukati zvakaenzana mukati memazuva 3-4 dzinogara rubvumo. Panguva imwe cheteyo, uye kubudirira kunobatsirawo neBP. In cerebrospinal mvura zvinodhaka wevasungwa haasi kupfuura 20%. Action pashure jekiseni mberi kusvika 2 maawa. zvazviri zvikaramba pashure nomumukanwa dosing mahwendefa "Sotageksal" kuti maawa 12. Analogs zvinodhaka zviri murwiyo ine sotalol hydrochloride, uyewo haana kubatwa muviri kunoitwa itsvo uye yabudiswa muna weti (90%) uye mutsvina yadzo Paavhareji mumaawa 10-20.

Ndokusaka varwere havachanyatsogoni renal uye Urinary hurongwa hunoratidza mishonga kuti muduku chipimo chemushonga. vanhu vakura vari kakawanda kuchengetwa zera-chokuita Kuipa renal ushande. Izvi zvinobatsira kuti chokwadi chokuti fuma unoratidzwa panguva nomumugwagwa kwaitora nguva mwero uye anogona -wedzera mumuviri. Saka, boka iri varwere zvinodhaka kushandiswa nokungwaririra uye chipimo chemushonga akatsunga nomumwe.

The mushonga unobatsira normalize exchange reokisijeni munyama, anobvisa kushatirwa, kufunganya, kushushikana uye zvimwe zvinhu zvine chokuita kakawanda uye kusimba sunga zvomwoyo.

"Sotageksal": mirayiridzo kushandiswa

Analogs zvinodhaka uye mumiririri zvinoshandiswa pamwe zita symptomatic cardiac arrhythmias yepakutanga, nokuti dambudziko ventricular arrythmia. Asi pane zvakasiyana kushanda muna varwere zvakafanana diagnoses. Naizvozvo, unofanira kugadza chiremba pashure kwazvo kuongororwa uye kunoparirwa yechipupuriro.

Kashoma muiti rakashandiswa kurapwa wevarwere vakambova psoriasis (psoriasis) kana vanotambura cheshuga pamwe havachanyatsogoni carbohydrate muviri. Chenjerera kugadza vanhu vane nhoroondo chisimbwa aripo, rinoreva "Sotageksal". Analogues zviri achigonawo kudzvinyirira muviri aikanganiswa sema kuitika. Achingwarira mushonga inoshandiswa kurapa varwere vane mwoyo nokukundikana, asingatani kakawanda dzegirini. Varwere vakambova myocardial infarction, arrhythmia pangozi acharodza panguva kugamuchira "Sotageksala".

Chipimo chemushonga uye kurapwa nguva

Zvichitsamira kwokuomerwa chirwere akatsunga uye ya zvinodhaka mishonga "Sotageksal". Mirayiridzo dzokushandisa (analogs angave nemamwe mirayiridzo mabiko) rine zvinotevera audzwa:

• hwendefa vakamedzwa yose, kwete rikamunya muchindwi uye mvura yakawanda;
• Kugamuchirwa rinoitwa kwemaawa 1-2 pamberi zvokudya;
• mushonga 2-3 kanomwe pazuva.

Early kurapwa daily dose haafaniri kupfuudza 80 MG (1 hwendefa) neBP uye tachycardia. Zvisinei, pasina zvinodiwa kuchirapa mugumisiro dose kwakawedzera. Zvishoma nezvishoma, pamwe penguva mazuva 2-3 riri kumamiriro 240-320 MG pazuva, asi chete muchipatara. Inonyatsobudirira iri zvishoma nezvishoma yakawedzera chipimo chemushonga 80 MG pavhiki.

The kunonyanyisa dose zvingava mahwendefa 6 pazuva zvinodhaka "Sotageksal". Analogues, kuti chipimo chemushonga izvo zvinogona yakawedzera kana chiremba anoongorora zvakafanira, anofanira vanogadzwa nomumwe. Kunyange kana pane ngozi kuupenyu, yaipedzerwa rinobata chirungiso haafaniri kupfuudza 480 MG pazuva.

Kana murwere chipo renal dzichipfekeka zvinetso, mishonga zvaiitwa dzakasarudzwa somunhu Zvaiitwa creatinine Clearance. Zvibereko zvayo (30 MG / Maminitsi), kuti dose iri yemanyorero wakaderedzwa kusvika maviri mana nguva.

Intravenous majekiseni akaita kaviri pazuva, huviri ampoule jekiseni 2 Rine mamiririta. The inotoda jekiseni zvishoma nezvishoma pamusoro maminitsi 5-7. Panguva kurapwa, zvinodiwa kudzora BP, kupomba, etsvo uye Urinary ezvinhu, creatinine Clearance mu serum.

umboo

Mari akasarudzwa kuti kurapwa kwezvirwere izvi:

• tachycardia, ventricular;
• Wolff - Parkinson - White;
• cardiomyopathy;
• ventricular rokusamhanyira anorova;
• mitral vharafu prolapse;
• Paroxysmal atrial fibrillation ari atria;
• neBP (cheBP);
• kudzivirira uye vabatwe myocardial infarction (dzimwe nguva).

In zvakakomba havachanyatsogoni renal basa, mumwe chiremba vanosungirwa nguva kuongorora wevasungwa yezviri fuma muropa serum uye kuchinja dose "Sotageksal" chinodhaka. Analogs of zvairatidza kuti kubvuma akafanana. Asi, pasinei ichi, ravo chinotsiva mumwe mushonga kune vamwe zviri zvachose wairambidza. Kudzimwa kurapwa ikaitika pakarepo, asi zvishoma nezvishoma. Chimbichimbi paimira anogona kukonzera kuparara kunotoda ezvinhu.

Contraindications

Chero antiarrhythmic mumiririri havangagoni kupiwa murwere, kusanganisira "Sotageksal". Analogs contraindications ndiwo chete, havagoni kushandiswa pasi zvinotevera ezvinhu:

• hypersensitivity kana idiosyncrasy chikuru fuma kana webetsero zvinoriumba;
• simba sinus angled;
• nemuumbi zvinoderedza kwemwoyo (bradycardia);
• chisingaperi obstructive pulmonary pezvakaitwa;
• zvakakomba Árbol asima;
• renal kukundikana;
• chenjera myocardial infarction;
• chenjera kana chirwere chemwoyo;
• cardiogenic kugwinha;
• elongated QT penguva urwere ;
• chevana zera;
• chisimbwa, sema rhinitis;
• pamuviri uye achiyamwa;
• akaderedza kumanikidzwa (hypotension);
• mukuru yokutindivadza;
• neronda rinonyenga;
• peripheral vascular chirwere;
• Kugadzirwa tachycardia mhando "pirouette" (ezvinhu iri panoonekwa kakawanda vakadzi kupfuura vanhu).

ruzivo Enough pamwe mushonga panguva yepamuviri haisi. Chete "Sotageksal" akagadzwa pamusoro zvinoratidza dzinokosha. Dzomuzana rokutanga trimester uyewo vangangokukuvadza fetus upenyu, uye ndichivatakura kunogona kutungamirira pamuviri. Hwakavimbika ongororo Data pamusoro kubvuma zvinodhaka vakadzi vane mwana achiri asina.

Mumwedzi mishoma yokurapa anofanira zvishoma wakaderedzwa kwemazuva 2-4 asati wakurukura, kana mukadzi angahutora panguva yose nguva pamuviri. Izvi zvinoitwa kuitira kuti achangoberekwa haana kudzvinyirirwa kufema mashandiro, bradycardia kana hypotension nokuda mushonga "Sotageksal".

Analogues hwakavakirwa sotalol hydrochloride anofanira vakarega kutora kana amai vechiduku riri achiyamwa, sezvo pafuma anokwanisa kupinda mumba mukaka uye kusvika kumusoro kuwanda ikoko. Kana zviratidzo kurapwa zvinofanira mberi, kuti achiyamwa nani kurega, achitsiva adaptive mukaka muvhenganiswa maererano nezera romwana.

Marwadzo uye ovhadhozi

Inogona nemigumisiro kuti zvemwoyo, kwemakemikari anobudiswa, Urinary, kufema, zvomudumbu uye nechepakati tsinga kushandiswa zvinodhaka "Sotageksal" kwenguva refu. Analogs kukonzera yakafanana nemishonga. Murwere vanogona:

• kupfupika mweya, kuwedzera angina kurwiswa, zviratidzo mwoyo kukundikana, marwadzo mwoyo, vasospasm, Raynaud kuti urwere ;
• kuda kurutsa, kurutsa, manyoka, dumbu marwadzo, kunyanya gassing, flatulence, zvakaoma bowel kufamba, chakaoma mucous membranes mumuromo;
• kufunganya, nokusagadzikana, kutya chirwere, aone zvinhu zvisipo, havachanyatsogoni gwenya kufambisa, kusanzwa, chinja kwemanzwiro, chakamira pakunodengenyeka zvine, kurukutika, kutemwa nomusoro, dzungu, kushaya hope kana, Ukuwo, wakawedzera hope, zviroto kuzvidya mwoyo;
• conjunctivitis, keratoconjunctivitis, kana chakaoma ziso syndrome (kunyanya varwere vanopfeka kuonana lenses nguva dzose), kuzvimba cornea, kuderera muzvavanoda kunhuwidza, marwadzo ziso, photophobia, havachanyatsogoni kutarisana acuity, kunzwa;
• yomuropa (mu vanhu vane chirwere cheshuga);
• bronchospasm, laryngitis, tracheitis;
• urticaria, dermatitis, ganda kuvaviwa, erythema, psoriasis, angioedema, vakawedzera vangadikitira;
• mukono potency mwoyo, marwadzo panguva ejaculation, vakadzi - ungaderedza libido uye kumwedzi zvirwere;
• nefivha, tsandanyama simba, kugwinha, cyanosis wamativi.

Kana zvikashandiswa zvakapfurikidza kunogona kuitika:

• kudzvinyirira pamusoro cardiac mabasa;
• kupfupika mweya;
• asystole, kufenda, simba, dzungu;
• cyanosis pamusoro wamativi;
• mhasuro chinyamunhari chinorwadza;
• bradycardia kune zvizere cardiac kusungwa;
• zvemwoyo kugwinha;
• bronchospasm;
• tachycardia.

Pasinei zviratidzo dzakakomba dzakadai ovhadhozi, rufu kwava kushoma. Kana mushonga chepfu vanofanira kutanga kunwa mishonga "Sotageksal". Analogs uye generics sotalol hydrochloride zvakanyanya goho kubva nemudumbu pashure ingestion absorbent zvinodhaka. Kana ovhadhozi symptomatic kurapwa kunoratidzwa. Muzviitiko zvokuva chepfu zvakakodzera gastric lavage uye kurutsa, kuchengetedza kukosha muupenyu mashandiro anoita nhengo dzomukati. Kunwisa mishonga kubviswa nokuda hemodialysis zvachose. Metabolic richikwidibira ropa shuga kunogona kuitika munguva varwere vanoomerera vaitofanira kudya kana nenzara.

Analogs uye generics "Sotageksala"

Sotalol hydrochloride huri chigadzirwa zvinoberekwa Switzerland uye Germany, pasi kutengeserana zita "Sotageksal". Analogues dzayo vanoonekwa uye zvimwe zvinodhaka zvakasiyana sezvamunoita, izvo kuwedzera imwe antiarrhythmic mugumisiro kuderedza kwetsandanyama, kuderedza BP uye kuvandudza kushanda atria. Idzi dzinosanganisira:

• "Inderal" "Inderal", "obzidan", "Pranolol" (active chirungiso - propranolol) inoshandiswa pakurapa ischemia, arrhythmia uye BP.
• "Pumpan" - Homeopathic mumiririri yakavakirwa muriwo zvinoriumba.
• "Magnerot" rine magnesium orotate dihydrate rinoshandiswa chokubata arteriosclerosis, kusagadzikana lipid muviri.
• "Korvitol" (metoprolol tartrate) ndiyo zvakabatsirawo kutemwa nemusoro.
• "Nebilet" (nebivolol hydrochloride) kunoratidzwa nokuda neBP, ischemic chirwere.
• "Qudesan" (donhwe) - munhu zvipenyu chinamatidzwa kunobva coenzyme Q10 kuti kudzivirirwa uye mishonga arrhythmias.
• "Etatsizin" (etatsizin) rinoshandisirwa vari tachycardia;
• "Arrhythmia" "Amiodarone" (amiodarone hydrochloride) zvinoshandiswa cardiac, tachycardia, atrial arrhythmia.
• "Propanorm" (propafenone hydrochloride) rinoshandiswa kana ventricular uye supraventricular arrhythmias.
• "Neo-Giluritmal" (praymaliya bitartrate) kunoratidzwa nokuda ventricular arrhythmias, tachycardia.
• "Korgard" (nadolol) iri vakagamuchirwa nokuda pakurapa angina pectoris, migraine.

Russia unobereka "Sotalol Canon" uye "Tenzol" pamwe chete vachishingaira wemafuta sezvo "Sotageksal". Analogues muMoldova, Ukraine uye pedyo kunyika Pharmacies vakareruka kupfuura pakutanga zvinodhaka. Mari zvinodhaka kunobva kunyika uye kambani. Mishonga Domestic kazhinji vane mutengo yekudyidzana yakaderera pane kumwe.

Reviews

Paiva rinokosha zvinoderedza nepfari kakawanda munguva atrial fibrillation, kana kutorwa akaramba "Sotageksal". Analogs anoshivirira Wongororo havasi kudaro zvakanaka. Hazvina nguva dzose zvinodhaka kubva vagadziri siyana akafanana, kunyange kana vaine chete nziyo. Vazhinji vanotya kuti anonyengera vagadziri anoratidza mukuru Kuwanda vanoshingaira wemafuta paminiti hwendefa kupfuura chaizvoizvo ndiyo. Nokuda kurapwa ichi kunogona kuuya inotarisirwa zvabuda. Reviews kuti "Sotageksale" Kusiyana neizvi, zvakanaka. Iye zvinobudirira kushandiswa kunzwisisa dambudziko zvemwoyo panguva mumatanho akasiyana.

Kazhinji pane zvishoma nezvishoma mune vakawanda mamiriro varwere pasi zvakaoma kurapwa. The mushonga hunokosha zvose cupping, uye ekudzivirira. Kutonga nezvinooneka wongororo varwere chirwere kuti "paroxysmal fibrillation," mushonga kunobatsira kuchengetedza zvakajairika mwoyo mutinhimira (inopiwa, kana kutorwa akaramba sezvo yokuzvigadzirisa kurapa). Zvisinei, varwere vanoti havana kuzoshinga kusimudza dose dzavo pasina chiremba dzinoenda nokuda ngozi chakakomba nemishonga.

Mimwe wongororo hazvisi zvakanaka chaizvo chaizvo mukurumbira zvinodhaka. Zvinonzi vaidavira kuti nezvehurukuro uye havazokwanisi kurapa kupererwa, microbial arrhythmias, hypokalemia uye hypomagnesemia. Zvinonzi kuzivikanwa kuti sotalol hydrochloride wokumwe pezvitsiga zvakaoma kuwana omunzvimbo Pharmacies. Vanhu vakajaira nguva dzose kushandisa nzira rwakawira nezvinetso wayo kutora. Saka, asati atanga kurapwa, iva nechokwadi chokuti uchakwanisa kuramba kwenguva refu.

Chii hazvigoni kubatanidzwa kugamuchira "Sotageksala"

Panguva varwere mishonga zviri chinodiwa kupa kutyaira, kuchovha, mudhudhudhu. Uyewo ngozi zviitwa zvose zvinoda zvakawedzera kutarisirwa uye psychomotor yevasungwa uye kukosheswa. Kana kugamuchira mamwe mari mukuderedza okuda angangoda hypotension. Zvinonzi rambidzwa chokubatanidza "Sotageksal" zvinodhaka zvakadai:

• jekiseni, sezvo atova anowedzera wevasungwa kwayo muropa;
• ions uye calcium yakawanda mhandu;
• zvinoreva kungopa kana inhalation rufimbi;
• Mao FIs;
• ayodhini tubhokisi fuma;
• diuretics;
• ergot alkaloids;
• tetracyclic antidepressants.

The mushonga hauna chinotarisirwa panguva imwe chete antiarrhythmics dzekirasi I uye III. Chinonziwo contraindicated pakugamuchira marwadzo zvinodhaka, sedatives uye antihistamines, antipsychotics, coumarin, relaxants. Ivo vanobatsirawo akasimba nechepakati tsinga depression. Mawa yokutindivadza kunotungamirira vawedzere BP uye depresses myocardial tishu. Zvinonzi rambidzwa kuita ganda bvunzo yokuziva marudzi allergens. Izvi zvinowedzera mukana anaphylaxis, angioedema, uye asphyxia.

Drug "Sotageksal" yakabudiswa muna Pharmacies kubudikidza mushonga. Separate Mabatirwo arrhythmia kuti zvingaita chakakomba nenjodzi. Saka, usati kutora mushonga, nguva dzose unofanira kubvunza chiremba.