Nzira uye mirayiridzo kushandiswa "Loraksona". Analogs uye nhoroondo

Chii chakadaro zvinodhaka se "Lorakson 500"? Mirayiridzo kushandiswa, zvainyanya ari mudziyo, uyewo chiratidzo chacho, chimiro, akafanana uye analogs zvinokurukurwa pazasi.

Kavha, chimiro, Kuronga zvinodhaka

Chii chimiro maitire nokuda vaiona nemishonga? Chii bhiri iri rinoti kurayira Chinyorwa? "Lorakson" ari crystalline guruva rinopfumburwa chena kana zvishoma yellowish, akaronga achigadzirira intravenous kana intramuscular mhinduro. The Kuronga medicament anosanganisira basa chirungiso akadai ceftriaxone. Ngachipiwe muchimiro ayo yavaibvisa munyu.

Uyewo, kuti zvinodhaka "Lorakson" mirayiridzo Chinyorwa iri rinotanga murwi wemagazini makadhibhokisi unosanganisira solvent sezvo mvura jekiseni.

Kugadzirira chidzidzo anogadzirwa girazi ndiro 10 Rine mamiririta izvo akaisa mumabhokisi bepa (chingatengeswa kana pasina munhu solvent).

Pharmaceuticals Pharmaceutical Products

Chii chambotaurwa nezvacho chinodhaka? Chii ruzivo rine mirayiridzo kushandiswa? "Lorakson" - mushonga unorwisa (cephalosporin) chizvarwa chechitatu, dzaizopiwa parenteral yaitonga. Rine bactericidal chiito.

With kukwanisa tunodzivisa kwetunhu musero membranes zvinodhaka kuchititadzisa kukura vakawanda giremu negative uye giremu-akanaka tusingaoneki.

Maererano nenyanzvi, ceftriaxone anoratidza haangosarudzi kugadzikana pamusoro Beta-lactamase (penicillinase, cephalosporinase), izvo anobudiswa nemabhakitiriya vakawanda.

Kinetics zvinodhaka

Sei Kubata chigadzirwa Anopararira pamusoro womunhu? Chii ichi inoti rinotevera mirayiridzo kushandiswa? "Lorakson" riri parenteral Kutarisirwa zvakanaka kupinda zvinenge zvose munyama uye muviri zvinwiwa.

With intravenous aizomupa ceftriaxone nokukurumidza runako diffuses munzvimbo interstitial fluid apo ayo antibacterial ehupfumi vari ainawo zuva.

Zvinofanira kuzivikanwa kuti zvinoshingaira chezvinonhuwira pomutumwa reversibly akasungwa kuna sealbumin. Nokuda duku zviri yokupedzisira ari interstitial fluid wevasungwa zvinodhaka mairi zvishoma kupfuura vari serum.

In chii mazwi mushonga rinobva murwere? Zvarinotaura pamusoro mirayiridzo kushandiswa? "Lorakson» vane sezvamunoita kwave rwa pamusoro, unoratidzwa kwemaawa 8 (pamwe bile uye weti). Zvinofanira kucherechedzwa kuti pasi pokudzora kwomudzimu intestinal Maruva chinoshingaira vanzwe of chishandiso iri wakashandurwa kuti akaneta metabolite.

In vachangoberekwa vacheche, hafu-upenyu vaiona mushonga 8 mazuva, uye vakwegura (anopfuura 70 years), iyi ndiyo 2 nguva yakawanda.

The kinetics zvinodhaka chaidzo zviitiko

Kana malfunctions renal maitiro uye pathologies chiropa ari mukuru vanhu pharmacokinetics ose ceftriaxone iri risina kuchinjwa, nehafu-upenyu nguva iri miforo dzisinei.

Kana itsvo basa iri kudzimika zvinokosha, kubviswa pakati zvinodhaka kunoitika achinyanya chete bile, asi kana kukuvaradzwa chiropa, ceftriaxone yaiwana ainyanya vachishandisa neitsvo.

In vacheche nendumure ane kuzvimba meninges medicament ichi vanogona kupinda munzvimbo cerebrospinal mvura. In vakuru vane yomumuzongoza pashure maawa 5-25 pashure kwezvinhu imwe chipimo chemushonga kuti ceftriaxone 50 MG / makirogiramu muviri uremu kakawanda ayo wevasungwa akapfuudza MIKA, iyo inodiwa kuti kudzvinyirira mabhakitiriya anokonzera chirwere.

umboo

Kana ndichifanira kuita zvinodhaka jekiseni "Lorakson 500"? Mirayiridzo dzokushandisa (majekiseni zvinofanira kupiwa chiremba chete ane ruzivo) rinoti mushonga chakagadzirirwa kubata zvinotapukira uye anogumbura zvirwere zvinokonzerwa nemabhakitiriya inonyatsoziva zvinodhaka. Saka, zviri kushingaira kushandiswa:

• yomumuzongoza;
• Zvirwere yokumusoro kufema turakiti;
• sepsis;
• Urinary turakiti noutachiona uye itsvo;
• noutachiona dzokubereka nadzo (kusanganisira mwandabvu);
• abdominal Zvirwere (kusanganisira anogumbura zvirwere ura, peritonitis, biliary turakiti chirwere);
• Zvirwere ganda;
• Zvirwere ari kufema turakiti (kusanganisira nemabayo);
• zvirwere, vagari uye mapfupa munyama;
• noutachiona vanhu vane ashaye kutapata.

Uyewo, zvinoreva Zvingaonekwa akaratidza kuti kudzivirira zvirwere maronda ari postoperative munguva.

Kurambidzwa kugadzwa

Pane contraindications rataurwa zvinodhaka? Zvarinotaura rinotevera mirayiridzo kushandiswa? "Lorakson" zvairatidza zvakatendeka pamusoro apa, hazvifaniri nezvaro zvinotevera nyaya:

• murefu hypersensitivity kune penicillins uye cephalosporins;
• ari trimester akazvitakura rokutanga.

With yambiro mishonga iyi inokurudzirwa vanhu vane chiropa chirwere, colitis uye enteritis. Uyewo, kungwarira zvinofanira kushandiswa kana NUC, hyperbilirubinemia muna vana vachangoberekwa mumakore maviri trimesters pamuviri, vakurumidze vacheche uye achiyamwa.

Mirayiridzo yokushandisa

"Lorakson" raitongwa varwere nomutsinga kana intramuscularly. The paavhareji daily chipimo chemushonga zvinodhaka kuti vakuru uye vana makore 12 iri 1-2 g kamwe zuva (ose maawa 24).

In Muzviitiko zvakaipisisa, uyewo zvirwere kuti zvinokonzerwa utachiona mwero nehanya, rimwe zuva dose kuti mumiririri uyu anogona ngazviwedzerwe 4 d

Newly akaberekerwa vana vachiita zvinodhaka 1 nguva pazuva inokurudzirwa zvinotevera chipimo chemushonga: 20-50 MG / makirogiramu (kusvika 2 weeks vezera).

Baby nendumure nevana makore 12, ari dose pazuva kuva 20-75 MG / makirogiramu. Kuyaruka vane muviri kurema 50 makirogiramu medicament dosages chinotarisirwa nedzevakuru.

Ya kurapwa pachishandiswa ichi kunobva chirwere.

Terms kugadzirira mhinduro

How kugadzirira mushonga mhinduro? Chii bhiri iri rinoti kurayira Chinyorwa? "Lorakson" kusunungurwa fomu iro rave kukurukurwa pamusoro, nokuti intramuscular jekiseni inofanira rakasanganiswa (1 g) muna 3.5 ml 1% - mhinduro kubva lidocaine, agozopinda zvikuru kupinda gluteal tsandanyama.

Kugadzirira Pfungwa yokuti intravenous jekiseni, 1 g madota zvinofanira rakasanganiswa muna 10 Rine mamiririta kwakadonhera mvura (chena). Kwokupedzisira mhinduro anofanira zvishoma nezvishoma akatanga kuva tsinga (nokuti 4 kwemaminitsi).

For intravenous aizomupa 2 g mushonga kunodiwa kuti mudutu 40 ml kugadzirisa (semuenzaniso, yavaibvisa chloride, dextrose kana fructose), wasunungurwa karusiyamu. aizomupa Izvi zvinofanira kuitwa kweinenge hafu yeawa.

Zviitiko ne-hunhu

Ko zvakaipa siyana zvinodhaka mhinduro "Lorakson"? Mirayiridzo dzokushandisa (majekiseni zvinofanira kuitwa chete muchipatara) anoti ari akapoteredza kushandisa mushonga uyu murwere anogona kuva:

• kuda kurutsa, leukopenia uye kurutsa, granulocytopenia, manyoka, hypocoagulation, kupatira, hemolytic kupererwa neropa, flatulence, lymphopenia;
• abdominal marwadzo, phlebitis, kuravira chinovanetsa, marwadzo achitevedza tsinga, stomatitis, urticaria, glossitis, neutropenia;
• pseudomembranous enterocolitis, infiltration uye nounyoro pane nzvimbo intramuscular kutarisira havachanyatsogoni chiropa basa;
• havachanyatsogoni renal basa, goiter, thrombocytosis, glycosuria, thrombocytopenia, oliguria, mapundu, azotemia, bronchospasm;
• Zvakawanikwa urea muropa, eosinophilia, hypercreatininemia, polymorphic erythema, cylinduria, epistaxis, hematuria, superinfection, anuria;
• nefivha, serum kurwara, fivha, angioedema, pruritus, dzungu, anaphylactic kuvhunduka, candidiasis, nomusoro.

Pamwe uye zviitiko ovhadhozi

Ovhadhozi of mari kunoratidzwa dzungu, nomusoro, paresthesia, kugwinha, encephalopathy uye pakoma. Kubvisa zvinhu izvi zvakavapo kushandisa symptomatic kurapwa, uye vari kutsigira anokosha muviri.

Mawa kurapwa pamwe ceftriaxone pamwe aminoglycosides kunowedzera antibacterial basa ravo. Kuitira kudzivisa hunokachidza mugumisiro nevamiririri aya achiita panguva dzakasiyana uye munzvimbo dzakasiyana.

Anoshandiswa zvakafanana "Loraksona" Platelet aggregation FIs uye NSAIDs pane mukuru mukana ropa.

Kana kuti mukagamuchira mumwe "loop" diuretics, pane mukana mukuru nephrotoxicity.

Viewed mishonga haawirirani panyaya iyi, sezvo mubatanidzwa uyu kunokonzera kwazvo kuda kurutsa, kurwadza kwacho vari epigastric nharaunda, kurutsa, Flushing, zvinoderedza ropa dzvinyiriro uye tachycardia.

Zvinonzi zvaisambobvumirwa kutaipa muna rimwe sirinji ceftriaxone nezvimwe inorwisa mabhakitiriya.

Similar zvinodhaka uye inofambiswa mishonga

Zvino munoziva kuti "Lorakson". Mirayiridzo yokushandisa, zvinoreva analogs vari munyaya ino.

Chii chinogona kutsiva mishonga? For zvinodhaka zvakafanana nyanzvi funga zvinotevera: "Ceftriaxone-Promed" "Ceftriaxone-Elf," "Tsefogram", "Tsefson" "Ceftriaxone-Protekh" "Ceftriaxone-Dzhodas", "Tseftriabol", "Tsefatrin".

Maererano mhinduro wevarwere, kazhinji anobata nzira vakashandisa kurapa yepamusoro zvirwere kufema uye kufema turakiti zvirwere. Kuongorora mashoko avo, tinogona zvakachengeteka kugumisa nokukurumidza chiito chacho uye yakakwirira kunyatsoshanda. Zvinofanira kucherechedzwa kuti kana uchishandisa mushonga uyu vamwe varwere paiva zviduku nemishonga kuti vaisarambidza discontinuation yokurapa.