Mushonga we "Lamicon": kurayirirwa, kushanda, kuongororwa, maitiro, kusunungurwa

Mishonga yakadai se "Lamikon" inodhura zvakadini? Mutengo wemishonga iyi ichaiswa munyaya ino. Uyewo mauri uchawana mirayiridzo yakajeka pamusoro pekushandiswa kwemishonga, zvinopesana, zvienzanidzo, zviratidzo, maitiro akafanana, mafomu ekubudiswa, kuumbwa nezvakadaro.

Kuumbwa, chimiro uye kugoverwa kwemishonga

Iwe unogona kutenga mishonga iri mumhando inotevera:

• Lamicon aerosol. Iyo spray ine chinhu chakashanda chakadai se terbinafine. Sezvimwe zvikamu zvemufananidzo uyu, propylene glycol, cetostearyl ester ye macrogol 20, benzoic acid, edidate disodium, mvura yejojo uye poloxamer 407 zvinoshandiswa.Kufuti inobudiswa mumaflaski ine dosing pump ye 25 g.
• Cream "Lamikon" (mafuta). Dzidziso inoti terbinafine inoshandawo sechinhu chinoshingaira chemufananidzo uyu. Zvimwe zvinoshandiswa zvemufananidzo uyu ndezvi: mineral oil, sodium hydroxide, white paraffin, cetostearyl uye phenylethyl alcohols, macrogol cetostearyl ester 20, propylene glycol, poloxamer 407 uye mvura yakachena. Pakutengesa mafuta aya anouya mumatope ane 15 g.
• Kugadzirira muromo "Lamicon". Matafura, murayiridzo waro wakaputirwa mune kadhibhodhi bhokisi, uyewo une chinhu chinoshingaira chakadai sedbinafine. Kana zviri zvezvikamu zvinowedzera, zvinosanganisira: chibage starch, sodium starch glycollate, microcrystalline cellulose, anhydrous colloidal silicon dioxide, hydroxypropylmethylcellulose uye magnesium stearate. Mateteteni ari mumiganhu yezvikamu zvinomwe.

Pharmacodynamics

Iboka rezvemishonga yemishonga iri pasi pekufungisisa istifungal. Maererano nemirayiridzo, chinhu chikuru chemugadziro uyu ndianlamine, iyo inoratidzira kushanda kwakasimba kwehutano pane nhamba yakakura yemhando dzakasiyana dzefungidzi.

Iyo fungicidal ye terbinafine (panguva yakawanda inowedzera) inowedzera kune dermatophytes uye fungi fungi, pamwe nemamwe marudzi e dimorphic fungi.

Zvichienderana nemhando, zvine chokuita nembiriso fungi, iyi mishonga inogona kuratidza zvose fungicidal uye fungistatic basa.

Pfungwa yekushanda

Ko "Ramicon" mishonga inoshanda sei? Iyo mirayiridzo inoshuma kuti uyu mumiriri anonyatsorambidza danga rekutanga re biosynthesis ye sterols mumakumbo emasero efungal. Mugumisiro weizvi inonzi intracellular cumulation squalene, uyewo ergosterol inoshaya. Izvi zvinotungamirira kukuparadzwa kwemasero emufungal.

Izvo zvinoshandiswa zvechiito chemugovereri mubvunzo zvakabatana zvakananga nehutano hwekudzivisa enzyme yakafanana squalene epoxidase, iyo ye cytochrome P 450 system.

Maererano nekuongororwa kwevanyori, mushonga we "Lamicon" haubatsiri pamigumisiro yemimwe mishonga, pamwe chete nehommonal metabolism.

Pharmacokinetics

Ndeipi iyo "Lamicon" mishonga yakabatwa? Iyo mirayiridzo inotaura kuti kune yekushanda kwekunze kana kwekunze, kubatwa kwezvinhu zvinoshandiswa zvinenge zvisingasviki ne5% yemushando unoshandiswa. Nokudaro, kushandiswa kwaro kusina kukodzera.

Nekushanda kwekunze, kugadzirira kunotanga kushanda kwayo uye kunoramba kwakabudirira kwenguva pfupi (inenge mazuva 8-13).

Nokuda kwekuchengetedzwa kwemishonga yakakosha inodhaka mu stratum corneum ye epidermis, yakawanikwa panguva yerapi, chirwere chefungicidal chechirwere ichi chinopfuurira kwevhiki mushure mekuregera.

Paunotora Lamicon mumuromo, chinhu chinoshanda chinowedzera muganda, misumpi nemvere. Kuisa mishonga yemishonga mumatumbu kunogadzirisa zvachose fungicidal properties.

Kubviswa kwemapiritsi ndeye 70%, uye yavo yakazara bioavailability 50%.

Izvo zvakagadzirirwa muhuwandu hwe 250 mg zvinokonzera kukanganisa kukuru muropa muawa nehafu. Iyo hafu yeupenyu inobatsira inenge maawa makumi matatu.

Zvokudya zvinongogadzirisa zvishoma kudengesa kwechirwere. Iine mapuroteni eplasma, iyo inoshanda inosunga kusvika 99.5%. Iyo mishonga inopinda panzvimbo pfupi nokukurumidza kuburikidza nedermis uye inowedzera mu stratum corneum.

Kugoverwa kwe "Lamicon" kunoitwa kuburikidza nemaronda anonyadzisa. Inowanikwawo mune bvudzi, ganda uye bvudzi follicles. Mumavhiki ekutanga erapi, mushonga unopinda mukati mezvipfeko zvepachipi.

Metabolized terbinafine nokukurumidza nekubatanidzwa kwe cytochrome P 450. Mushure mokuchinja kwehupenyu, kusagadzikana kwemasabolites kwechirwere kunodedzeswa neitsvo.

Apo chiropa neitsvo zvakashata, muyero webrigabine kuregera kunonoka zvakanyanya, izvo zvinokonzera kuisa mukati maro plasma yakakwirira.

Zviratidzo zvekushandiswa

Ndeipi chinangwa chemishonga yemunharaunda yemishonga "Lamicon"? Mafuta, murayiridzo wezvakatsanangurwa pasi apa, uye spray ine zviratidzo zvinotevera:

• Fungal skin lesions, iyo yakakonzerwa nefungi yejeri Trichophyton, Microsporum uye Epidermophyton (dermotophytia yemakumbo, groin, trunk nevamwe);
• Multicolored (kana pityriasis) lichen, yakabva pamigumisiro yefungi Malassezia;
• Candidiasis yeganda, iyo yakatsamwiswa nefungi ye genus Candida.

Ndeipi chinangwa chekushandisa mifananidzo yemuromo yemishonga "Lamikon" (mapiritsi)? Iyo mirayiridzo inozivisa pamusoro pezvirevo zvinotevera:

• Zvirwere zvefungal zveganda kana kupararira kwavo, kukanganisa kana kuoma kwakanyanya zvokuti vanodikanwa kutarisirwa nemugwagwa wepamuromo (yakagadzirirwa chete nachiremba);
• Mycosis yemusoro uye onychomycosis (kukuvara kumapapiro echipikiri).

Inofanira kunyanya kuzivikanwa kuti mahwendefa eLamikon haana kushandiswa kurapa varicolored (kana kushungurudzika) nhema.

Contraindications for use

Ndezvipi zvinopesana nezvinofanira kuitwa iwe usati washandisa mushonga "Lamicon"? Iyo mirayiridzo inotaura kuti kunongorambidza zvachose kumarudzi ose emishonga iri mubvunzo ndiyo hypersensitivity kune zvinhu zvayo.

Kana iri nguva yekuzvitakura, utana nekuyamwisa, izvo zvinopesana zvakasiyana.

Mafuta "Lamikon": mirayiridzo yekushandiswa

Maitiro akadaro emishonga se spray uye mafuta, zvinoratidza maitiro avo ekunze. Usati washandisa iwo kurapwa kwezvirwere zvefungal, unofanira kutanga uchenesa uye uomesa ganda rakagadzirirwa.

Zvichienderana nekuoma kwechirwere uye rudzi rwepathogen, mushonga we "Lamikon" (mafuta anonhuwira) unoshandiswa kaviri pazuva. Aerosol inoshandiswa panguva imwe chete.

Mucheka unofanirwa kushandiswa kwete chete paganda rakagadziriswa nefungus, asiwo nzvimbo dziri pedo naro. Izvo zvinodikanwa kuita izvi nenzira yakasara, zvishoma nezvishoma kuisa mafuta muzvivharo.

Kana chirwere chinotapukira chiri pamwe chete ne-intertrigo (somuenzaniso, pasi pemakumbo emamota, mumugwagwa, pakati pezvigunwe kana kuti neminwe), ipapo nzvimbo dzakarapwa dzinofanira kuvharwa nebandini yegasize (kweusiku hwose).

Kushandiswa kweaerosol

Ndinofanira kushandisa sei Lamicon spray? Nyanzvi dzinoti iyo inoshandiswa muhuwandu hwakakwana hwekusimudza nekupfira kune dzimwe nzvimbo dzinokanganiswa nefungi, pamwe chete nehutano hwakanaka pedyo navo.

Nguva yekurapa nemishonga yemunharaunda inoenderana nekuoma kwechirwere (kusvika kumavhiki maviri).

Kununurwa kwemurwere kunoratidzwa mumazuva mashoma. Kuti uwane hutano hunobudirira, unofanira kunyatsoteerera kumirayiridzo, usati wadarika kushanda kunotevera uye usarega kuporesa zuva risati rasvika. Kana zvisina kudaro, kune ngozi yakawanda yekudzoka zvakare.

Nzira yekutora mapiritsi?

Iboka rezvemishonga inoshandiswa nemishonga ndeyomurairo. Anotaurawo nezvekutora mhinduro iyi.

Sezvo mutemo, mapiritsi "Lamikon" anorayirwa vana kubva pamakore matanhatu, pamwe chete nevarwere vakuru. Kunwa kwemishonga yemuromo kunopfuurira kusvikira zviratidzo zvehosha yehutachika inonyangarika zvachose (zvichienderana nemamiriro ayo uye kuoma).

Chirwere che sachet yemishonga iyi ndeye 250 mg kuvanhu vakuru, uye 125 mg yevana inorema 20-40 kg. Nokuremera kukuru, mwana wacho anongororwawo 250 mg yemishonga.

Nguva yerapi ye trichophytosis uye candidiasis yeganda masvondo maviri kusvika ku4, uye nokuda kwekuvhara dermatomycosis, inomira masvondo maviri kusvika matanhatu.

Zvirwere zveFungal zvepamusoro zvinowanzoonekwa kune vana. Sezvo mutemo, ivo vanogona kunakidza kurapwa, kana mushonga uyu unoshandiswa mune chiremba chinorayirwa dhidziro kwemwedzi.

Kurapa kweyayymymycosis inotora masvondo matanhatu kwezvipikiri zvemaoko uye 12 - kwezvipikiri zvemakumbo. Nekukura kwakaderera kwepail plates, kurapa kunogona kuwedzerwa.

Zvakaipa Kuchinja

Kugadzirira kwemukati "Lamikon", iyo yakafanana nayo inoratidzwa pasi apa, inogona kuita kuti zviratidzo zvakadai seganda rinotarisa, kupisa, kuchenesa, kurwadziwa, kutsamwa, kuvepa, kuvepa, kunyeka. Ikoko kunogonawo kugadzirisa zvirwere.

Paunotora mahwendefa, zvinotevera zvinenge zvisingadiwi zvinogona kuitika:

• Neutropenia, agranulocytosis, Lyell's syndrome, pancytopenia, Stevens-Johnson chirwere;
• Thrombocytopenia, maitiro anphylactoid, zvinonaka, zviratidzo zve lupus erythematosus, misoro;
• Photosensitivity, paresthesia, hypoesthesia, dyspepsia;
• Utsivi, kunzwa nechembera, chirwere, kurasikirwa kwechido;
• Kuwedzera kweporioriasis, nhesaa, psoriasis-like rashes, kurwadziwa mumimba, myalgia;
• Urticaria, arthralgia, rash, generalized pustulosis, kurasikirwa nevhudzi, kuwedzerwa kwehuwandu hwevhiri hwechiropa;
• Kunzwa kwokuneta, hepatobiliary kusagadzikana, jaundice, hepatitis.

Analogues uye mari yezvinodhaka

Mishonga "Lamicon" inodhura zvakadini? Mutengo wechirwere ichi unobva maitiro ayo. Mafuta uye spray zvinogona kutengwa kwema 180-220 rubles, uye mahwendefa - makumi matatu nemazana matatu nemazana makumi mana nemaviri.

Kana iri mifananidzo, pakati pezvinonyanya kubudirira, kune nzira dzakadai se "Amorolac", salicylic acid. "Mikoseptin", "Nitrofungin", "Mikolak", "Exoderil".

Kuongorora nezvechirwere

Kuongorora kwevaya vakashandisa mushonga uyu "Lamicon", vane zvakanyanya kunaka. Varwere vanorondedzera kuti kurapa kwakanaka kwemishonga iyi kunoonekwa mazuva mashomanana mushure mekushandiswa kwayo kushanda. Sezvo mutemo, pakuguma kwemaitiro ekurapa, chirwere chinouraya chinonyangarika zvachose.

Muzviitiko zvakakomba, vanachiremba vanokurudzira kuunganidza mafomu ekurapa (semuenzaniso, mahwendefa namafuta, spray uye mahwendefa).

Mukuwedzera kumashoko akanaka, pane maitiro asina kunaka pamusoro pemishonga "Lamikon". Kazhinji ivo vanobatanidzwa nekusava kwayo kwayo. Zvisinei, nyanzvi dzinopikisa kuti izvi zvinongogoneka chete nekurapa kwekunyorera kusinganzwisisiki kumushonga kana kushandiswa kwayo zvisina kunaka. Nokudaro, usati washandisa mafuta, mapiritsi kana kuti spray inokurudzirwa kuti uone chiremba uye uise pathogen yehosha yefungal.