Inosimudzira prolactin: zvinokonzera, zviratidzo, kurapwa, migumisiro

Kana kwakakwidziridzwa kemikari prolactin, ari anetseka kumwedzi uye hormone nomwero, uye pane kushaya mbereko kana matambudziko akatakura mwana. Saka, vakadzi vanofanira kuona panguva yayo dhigiri ropa panguva kuronga pamuviri.

Prolactin anogadzirwa pachishandiswa pituitary shwanu - kwemakemikari anobudiswa shwanu yaiva muuropi. Hypothalamus anodzora izvi. Mahomoni akanyatsojeka nehanya nechitarisiko zvinhu. Saka, yakakwirira prolactin zvivepo zvinotevera:

• zvinodhaka;

• renal kukundikana;

• kushushikana;

• cirrhosis;

• hope;

• Cushing kuti urwere;

• Addison nehosha ;

• acromegaly;

• sarcoidosis;

• neyrotuberkulez;

• bundu;

• ari postpartum kumwedzi;

• pamuviri;

• munyatso dzishande;

• achiyamwa;

• zvepabonde;

• yokutindivadza;

• kukuvara pakuvhiya chipfuva.

Panguva dzakasiyana pane ichitanga kemikari pamwero muropa zvichisiyana 6 kusvika 28 kumar / Rine mamiririta. Kuti vawane yakavimbika nemigumisiro haigoni kubatwa pashure Kuongororwa kurara kana maitirwo ezvinhu. The secretion pamusoro prolactin rikauya pulsed, kakawanda zvaanoda chokutambudzika kutenderera. Panewo nokufamba zuva nezuva raro yakati sandara, Somuenzaniso, pashure wakasvinura kemikari wevasungwa duku. Pashure akotsira ayo secretion kunowedzera uye inokura muchiroto.

Mumwe pavatatu varwere vanenge kwakakwidziridzwa prolactin, akawana pituitary adenoma. Kana saizi yayo huru, kemikari pamwero kunopfuura 100 kumar / ML. Yakaderera kunogona microadenomas panguva hukuru diki, kwete kuona nokuda X-ray.

Nzira dzakawanda idzidzise kuti chirwere kuti pituitary anomera - a MRI. Zvakakodzera zvakaitika kuronga mwana, kana pane fungidziro ane adenoma, sezvo bundu guru anogona kukonzera matambudziko.

Dimensions pituitary microadenomas haapfuuri 1 cm. Vanokura zvishoma nezvishoma uye kazhinji benign. Macroadenomas dhayamita kupfuura 1 cm. Ivo achiperekedzwa nomusoro, kuchinja kutarisana minda uye kurasikirwa nayo dzimwe nguva yakakwana. Pamusoro kuonekwa macroadenoma zvakakodzera kubvunza ane neurosurgeon. Anoita sarudzo nezvebasa. Panguva pamuviri microadenomas kazhinji handishanduki, asi mapundu makuru kukura muna 20% zviitiko kukura.

Prolactin chiri kakawanda kwakasimudzirwa mu renal kukundikana (refu). Kana itsvo transplantation munhu normalization kwaro secretion.

Kana prolactin rakakwirira, chinangwa pakurapa zvinotevera:

• kuderedza kwayo chechetere;

• adzorere kutenderera;

• kuderedza bundu saizi, kana chipo.

Mumwe mishonga inoshandiswa kuderedza kemikari - ndiye Parlodel, inova dopamine agonist. It kuchititadzisa ari secretion kuti prolactin nokuita kuti masero receptors muuropi. Dose kunobva kwokuomerwa uye hunhu chirwere. Pashure pakatanga bromocriptine kutenderera anodzorerwa pashure avhareji vhiki 7. Kunyange zvazvo vamwe varwere richiwanika mumazuva mashomanana.

Bromocriptine Kazhinji kutora kanoverengeka pazuva. ari dose anogona ngazviwedzerwe kana zvakakodzera. Treatment vanofanira kugara zvinogara anoverengeka pashure pokudzorerwa kumwedzi kudzivirira dzokororo. Side migumisiro bromocriptine:

• nekuneta;

• dzungu;

• kurwadziwa nemusoro;

• kurutsa;

• muromo yakaoma;

• svoto.

Kuwedzera prolactin kunogona kukonzera hypothyroidism. Kugamuchira Gomonov iyi nyaya inosvitsa normalization vayo chechetere.

Zvairatidza kuti prolactin kuongorora zvinotevera:

• osteoporosis;

• gynecomastia;

• yakaderera potency uye libido;

• hirsutism;

• kufutisa;

• Heavy rutarinhari;

• lactation zvirwere;

• kushaya mbereko;

• anovulation;

• zamu;

• kusarudzwa zviri munyatso;

• amenorrhea, oligomenorrhea;

• cyclic marwadzo zamu.

Saka, prolactin yakawedzera, kazhinji nokuda pituitary adenomas. Mukuwedzera, chikonzero zvinowanzovapo zvayo yakakwirira yevasungwa ndiyo hypothyroidism. The zvakawedzera Kuwanda prolactin kunotungamirira nokuvhiringidzirwa yekutevera nerevane pasina ovulation, saka pamuviri uye vana anova zvisingaiti. Treatment ine kuderedza mwero yaro, kubviswa chirwere chinokonzera uye kupora yatinofema.