Homocysteine. Norma zvinhu zviri muropa

Homocysteine - zita sarufa tubhokisi acid, kunoitika mumuviri somugumisiro kubudiswa methionine. The peculiarity izvi zvinhu ndechokuti totaura munhu kuburikidza chikafu. Methionine akawanda anowanikwa nyama, mazai uye mukaka. Zviri nedanho kugaya zvokudya nomuviri, rinoumbwa methionine uye homocysteine.

Ndozvakajairwa iyi fuma ari dzichichinja muupenyu hwomunhu. With zera, nenhamba zviri zvishoma kumuka. Asati kutanga kuyaruka kuti vasikana nevakomana homocysteine pamwero fuma ane wokuyera 5 mol / L, ndiye anenge chete. Panguva yokuyaruka padanho achisimuka 7 mmol / L, uye vechiduku iri kuwedzera zvakawanda raidudzwa kupfuura vasikana.

Kana isu nezvazvo vakuru, varume homocysteine, vane ndeyokuva kumativi 10 mmol / L, yekudyidzana kupfuura vakadzi. Vakwegura munhu anova, ari LEVEL rake asidhi iyi.

Pregnant Vakadzi homocysteine kungava zvishoma yakaderera. Izvi zvinonyanya kuoneka mune trimesters maviri pamuviri rokutanga. Muchiitiko chino, musavhunduka pamusoro chokupika fuma homocysteine, taizviisa nayo anonaya pashure 3 Mazuva azvarwa. Pashure rutapudzo of iine acid chechetere hwezvekukurukurirana placental kutenderera.

zvinhu izvi kuunganidza ari muviri, kunovhiringidza, akafukidza epithelium, yomukati masvingo arteries, zvichizoita maburi kuumbwa. Calcium remafuta akawandisa, precipitating ukama pamusoro, kusimudzira paumbwe sclerotic plaques. Izvi zvinotungamirira ndechokuti mudziyo inofambidzana makavhara, zvichiita thrombosis kana atsamwira, zvichikonzera sitiroko zvingamuka, kuti zvemapapu embolism kana myocardial infarction.

Vanhu vanenge kwakakwidziridzwa homocysteine pamwero, pasi kwaita cheAlzheimer , uye kunyange kugadzira penga nokuda kokuchembera dementia. Uye akabatana cheshuga, vascular yematambudziko zvinowanzoitika (nephropathy, retinopathy, etc.).

Homocysteine vari zano kuti aone vanhu vose vane nhoroondo chipo arterial kana venous thrombosis, ischemic mwoyo chirwere. Uyewo vakadzi yakaonekwa gynecological zvirwere, uye vane hama dzepedyo vakatambura yomwoyo, sitiroko kana thrombosis.

Zvinobatsira kuziva padanho homocysteine asidhi kuongorora. Blood zvakabudiswa zvinofanira kuitwa usina chawadya (pashure zvokudya anofanira kutora maawa masere kana kupfuura).

Kuwedzera chokupika ichi zvinhu zvingava nokuda kwezvikonzero zvinoverengeka:

• Vitaminodefitsitnoe mamiriro, kunyanya ane kushayikwa kwemavhitaminzi B6, B1, uye 12, uye folic acid.
• Kusvuta uye kushandiswa kakawanda kofi (manhamba kungawedzera 3 mmol / l).
• Ndakagara mararamiro.
• Doro.
• Mishonga. Izvi zvinoshandawo zvikurukuru kugadzirira "MTX" - folic iine acid antagonist (tanzi psoriasis), uye anticonvulsant mishonga (fetitoin - anobvisa folic asidhi ari chiropa), nitrous oxide (kushandiswa yokutindivadza), metformin (chirwere cheshuga uye polycystic ovary urwere) , aminophylline (anoshandiswa Gynecology nokuda mabatirwo preeclampsia, anovanza mugumisiro vhitamini B6) uye hormone pamuviri.
• Renal insufficiency.
• Psoriasis.
• Neleukemia.
• Diabetes mellitus.
• Hypothyroidism.
• Zvirwere zvomudumbu turakiti, kukonzera malabsorption mavhitamini.

Isu moms pokurera homocysteine kunogona kukonzera zvakakomba yematambudziko panguva yepamuviri: intrauterine kukura retardation, placental abruption, uye kunyange rufu fetus. Hyperhomocysteinemia - chikuru chinoita afunge kupfupfudzika, mukuwedzera, vana vanogona kuzvarwa aine Neural chubhu vakaremara uye clubfoot. Chete chikonzero kunogona kukonzera kushaya mbereko vakadzi, apo muchibereko embryo zvisisakwanisiki.

Richikwidibira homocysteine kuchengetwa nemultiple sclerosis.