Drug "mebendazole". Mirayiridzo yokushandisa

Drug "Mebendazole" ( "Vermoxum", "Vormin") riri kuonekwa zvikuru vanobudirira anthelmintics. The mushonga inowanika hwendefa chimiro uye kumisa. Its vanoshingaira chirungiso - mebendazole.

The mushonga ane chakarondedzera anthelmintic basa. Inonyatsobudirira zvinodhaka nokuda trihotsefaleze uye enterobioze. Mishonga kutigumbura kubatana kwetunhu cellular tubulin mune honye, kuchambokanganisa kushanda cytoplasmic microtubules uye chinonditadzisa shuga Utilisation uye kuchititadzisa paumbwe ATP.

Pamusoro pokugamuchira medicament wefodya muduku pamwero. The mushonga ane hwakanyatsorwisa yakaderera bioavailability, nokuda kudunhu kwokutanga muviri uye zvakakwana pasi solubility. Medicament "Mebendazole" (gwaro rine mashoko akadaro) yabudiswa muna mutsvina yadzo rinenge zvachose.

The mushonga ari ushandiswe kubvisa cestodes, nematodes. Zvairatidza kuti mabiko ayo anosanganisira hookworm, ascariasis, Enterobiasis, trichinosis, trichocephalosis. Drug "mebendazole" mirayiridzo Chinyorwa anokurudzira kuti iwe kushandisa echinococcosis, taeniasis, strongyloidiasis. The medicament riri basa uye kusanganiswa yaingopambwa.

Drug "mebendazole" mirayiridzo kushandiswa haabvumiri dzokushandisa kwazvo kusagadzikana chiropa, hypersensitivity kwairi. Not varumbidzwa mishonga uye vana pasi makore maviri.

In kushandisa mushonga uri yaitwa muhombe helminthic kupindirwa uye zvakakwana kukurumidza nokubviswa chisvetasimba zvingaitika (dzimwe nguva), abdominal marwadzo (zvinopfuura), kutemwa, manyoka. Dzimwe nguva pane svoto kana kurutsa. Refu kurapwa vaine mishonga kuti medicament echinococcosis mune zvimwe zviitiko vakacherechedza neutropenia. Possible divi akadaro wo eosinophilia, uye kupererwa neropa. Mune zvimwe zviitiko, Varwere panguva kurapwa pamwe mushonga akazviratidza neutachiona (mapundu, angioedema, kuvaviwa kana mikoko). Kashoma kuchengetwa bvudzi kurasikirwa, uyewo cylindruria, hematuria.

Varwere vakura kupfuura makore gumi pa enterobioze mushonga "mebendazole" mirayiridzo Chinyorwa anokurudzira uwandu zana milligrams. Children pasi pemakore gumi kugadza milligrams maviri nemashanu kana makumi mashanu. The gadziriro iri nyaya chinobviswa kamwe. Mukushandisa yechipiri ane wakawedzera mukana wokutapukirwa rinoitwa zvakare medicament - pashure maviri kana mana mavhiki, nenguva chipimo chemushonga.

Kana ankilostomidoze, ascariasis, trihotsefaleze vana uye vakuru zvinodhaka riri ushandiswe kaviri zuva nezuva milligrams zana (mangwanani uye manheru). Treatment rinoitwa kwamazuva matatu.

Kana zvakasiyana yaingopambwa, strongyloidiasis, taeniasis yakarumbidza dose nevakura - milligrams mazana maviri kaviri pazuva. Vana akataura kaviri pazuva rimwe zana milligrams. Treatment mberi kwemazuva matatu.

At trichinosis zvinodhaka "mebendazole" mirayiridzo Chinyorwa anokurudzira kushandisa zvinotevera zano: mumazuva matatu okutanga - katatu pazuva 200 kana 400 milligrams, kubva wechina regumi zuva - katatu pazuva 400-500 milligrams.

Kana echinococcosis raitongwa kaviri daily 500 milligrams zvinodhaka (mumazuva matatu okutanga). Muvhiki mazuva matatu, asi kakawanda chikumbiro ichiwedzerwa 3 nguva (chete chipimo chemushonga kuruboshwe). Zvadaro, zvavakabvumirana daily dose 25 kana 30 milligrams por kilogram kurema muviri, matatu kana mana mishonga.

Nechinyoreso ovhadhozi mari vakachengeta kurutsa, manyoka, uye svoto. Panewo abdominal chinyamunhari chinorwadza. Muzviitiko izvi gastric lavage uchishandisa potassium permanganate anogadzirisa pingi rakachenuruka. Kubvumirwa kushandisa kusashanda kabhoni.

The feasibility kushandisa zvinodhaka "mebendazole" panguva yepamuviri uye lactation nyanzvi anosarudza. Panguva yose nzira yokurapa kunofanira kunyatsoongorora utsanana. Zvinokurudzirwa kuti va- kurapwa vose vomumhuri.

Asati kushandisa zvinodhaka "mebendazole" vanofanira chiremba.