"Atorvastatin": wongororo, analogs, akafanana uye mirayiridzo kushandiswa

The inonyanya zvinodhaka chakagadzirirwa kuderedza kwevari zvachose remafuta akawandisa uye LDL ndiye "Atorvastatin". Testimonials nezvazvo zvakawanda, kunyange zvazvo kunaka chigadzirwa kunosimbiswa yokuora zvidzidzo. Panguva iyo mushonga une imwe chete dzakazara mukwikwidzi - "Rosuvastatin" (uye ayo generics). Nokuti zviri pachena kuti "atorvastatin" gadziriro anoshivirira uchapupu varege kupa chinangwa ruzivo. Saka, kuongorora zvinokonzerwa ayo zvaida hwakadzama Kuongorora mashandiro basa uye zvatinopiwa ari kurerekera mirayiridzo kushandiswa.

Systemic mushonga fuma characterization

Atorvastatin ndohwaJehovha pharmacological kirasi chizvarwa statins rwechitatu. By zvichivhiringidza kuti enzayemu anokonzera endogenous kwetunhu remafuta akawandisa, zvinoderedza uwandu atherogenic lipoprotein hacho. Low arambe achirema chakapatsanurwa (LDL) anogona kuwedzera deposition kuti remafuta akawandisa uye kukonzera zvirwere mhinduro iri endothelium, nokuda izvo kukura Dombo.

Kufanana nevamwe statins, atorvastatin yekudyidzana zvinoderedza uwandu LDL, uye saka yekudyidzana DZEMUNHU DZINODZORA kukura Dombo. In muitiro uyu kwayo involution haina kuchengetwa, uye dhayamita kuti munhu coronary tsinga (kana mumwe atherosclerotic), chinoramba chete. The kunotoda kushanda - kuderera kukura nechirwere chemwoyo, cerebrovascular kana chirwere arterial insufficiency repasi maoko nemakumbo.

"Atorvastatin": zvairatidza yokushandisa

Asati kupinza kunodiwa kuti havatsananguri zvairatidza kuti kushandiswa kwezvinodhaka. Ivo zvinobviswa inokosha mashandiro chiito uye kusonganirana remafuta akawandisa-richikwidibira kushanda. Range kuti zvairatidza:

• nhaka (rwapedyo) hypercholesterolemia, heterozygous;
• polygenic (chikuru) hypercholesterolemia kirasi IIa maererano Fredrickson;
• Combination (IIb) dyslipidemia;
• Homozygous rwapedyo hypercholesterolemia;
• hypertriglyceridemia (kurapwa pamwe statin akabatana zvokudya uye muviri);
• mamiriro chokuita atherosclerotic vascular maronda mwoyo rusvingo, uropi, itsvo, migumo;
• neBP rurefu zvemwoyo pangozi;
• kudzivirirwa chakasimba coronary zviitiko tikafunga yaivapo atherosclerotic maronda ari coronary arteries;
• kudzivirira myocardial apiwa infarction kana chepfungwa sitiroko.

kuverengwa izvi kuona zviitiko kana kunodiwa kugadzwa "Atorvastatin" chinodhaka. Doctors pamusoro kushandisirwa zvakajeka zvinoratidza kudiwa ichi. Chinhu yakaonekwa kuti ndeyechokwadi chokwadi kuti statins, kusanganisira "Atorvastatin" wayo vakawanda generics ngozi zvikuru kardioform acetylsalicylic acid, kunyange saizvozvo kubatsira kuderedza mukana wokuita nekukudziridza wokutanga myocardial infarction wodzokorora nyaya.

zvinodhaka analogues

Mahwendefa All "Atorvastatin", iro akaongororazve inogona kuverengwa pazasi, zvinoberekwa nemakambani anogadzira mishonga yakasiyana. Kakawanda, mazita zvinodhaka dzakachinjwa, izvo zvinoita kuti patented. Trade mazita analogues, ndiko, zvinodhaka kuti ane atorvastatin sezvo yezviri zvinoriumba, zvinotevera: "Anvistat" uye "Atokord", "Atomas" uye "Ator", "Atorvoks" uye "Atoris", "Vazotor" uye "Lipoford" "Lipitor" uye "Liptonorm", "Novostat" uye "Torvazin", "Torvakard" uye "Tulip".

Uyewo, dzimwe vagadziri zvibereko mushonga wavo "Atorvastatin" (unogona kuverenga wongororo pazasi) pasi kutengeswa zita chete. "Actavis", "Vertex", "Izvarino Pharma", "ALSI Pharma", "Canon Pharma" Obolentsenskoe mishonga kambani, "Protek-SVM", "North Star", TABUK Pharmaceuticals, din email Pharmaceutical Industries, uye vamwe kubereka zita zvinodhaka chine INN ( "atorvastatin") uye tsika nokunyaradza. Muenzaniso "Atorvastatin din email", wongororo iyo asimbise ayo kunotoda kushanda.

mamiriro

Vasiyana mushonga 'atorvastatin' mirayiridzo kushandiswa, wongororo uye kurapwa nhungamiro dzisina mashoko pamusoro kusiyana chipimo chemushonga siyana. In tsika, misiyano yakadaro iriko, uye ivo waidzora simba pamusoro kuchirapa chiito. Chinokosha kuti nokukurumidza wouya kuchirapa mugumisiro wacho dose. Ndokusaka idzidziso "Lipitor" ndiro bhuku yemabviro zvinodhaka.

The chipimo chemushonga chimiro unotora atorvastatin karusiyamu Mahwendefa uye nevamwe. Ekupedzisira, akavapindurawo, rinoumbwa calcium carbonate, microcrystalline cellulose, lactose monohydrate, polysorbate 80, yavaibvisa croscarmellose, magnesium stearate, hydroxypropylcellulose, talc, titanium dioxide, polyethylene glycol, hydroxypropylcellulose, simetikonovoy emulsion, benzoic uye sorbic acid.

Vasiyana yepakutanga zvinodhaka "Atorvastatin" mirayiridzo Chinyorwa (wongororo uyewo iyi) harina ruzivo pamusoro uremu nerimwe zvinoriumba. Ichi zvokutenga chakavanzika American kambani Pfizer HCP CORPORATION. mumwe chipimo chemushonga chimiro "Lipitor" akadaro anotibvumira kuita kuramba Kuwanda atorvastatin muropa.

Combined chimiro "atorvastatin"

Mukugadzirira "Atorvastatin" mutengo (murefu uchapupu ngaadarowo) hunowanikwa-siyana varwere. Chinhu kufamba mishonga kuti dzinogona kubatanidzwa nezvimwe makirasi zvinodhaka. Kakawanda, "atorvastatin" uye dzimwe statins anobudiswa yega, kureva, imwe hwendefa chimwe chete kushingaira chirungiso. Zvisinei, pane yaisanganisa siyana.

Mienzaniso inosanganisira zvinotevera zvinodhaka: "Kaduet", "Duplekor", "statins". Pano, "atorvastatin" iri pamwe amlodipine, mumwe karusiyamu chiteshi blocker, rinova rinowanzoshandiswa mishonga cardiac zvirwere. The chipimo chemushonga zvinodhaka anosarudzwa chiremba.

Standard chipimo chemushonga "atorvastatin"

Drug "Atorvastatin", zviratidzo, nezvakawanikwa vanorumbidza pamusoro kunotoda kushandiswa yatiri munyaya kwataita, inowanika muna matatu mureza dosages: 10, 40 uye 20 MG. A zvikabatanidzwa gadziriro "Kaduet" rine 10 MG ose atorvastatin uye amlodipine 5. "Statins" anogadzirwa kaviri: 10/5 uye 10 / 10mg. Mukugadzirira "Duplekor" 4 chipimo chemushonga kuti atorvastatin uye amlodipine: 10/5, 10/10, 20/5, 20/10 MG. Izvi zvinoderedza uwandu mahwendefa varwere vane kushandisa uye statins uye calcium yakawanda mugero blockers kuti kurapwa kwezvirwere. Izvi zvinoitwa uye vasanyanye mutengo kurapwa.

Kusarudza rakasiyana "atorvastatin"

kunoreva First dzine atorvastatin ukabatwa pakutengeswa ndiye "Lipitor". Ndiwo mushonga yepakutanga, iyo akaita miedzo. Gare gare kwakatungamidzwawo vamwe zvinodhaka pasi mamwe mazita. Nokuti kunyoresa waida chete chakarongwa simbiso bioequivalence "Lipitor." Panguva iyoyo, inogona dundundu pamusoro vagadziri shoma. Naizvozvo, kuwana chiremba mushonga kuti aripo zvinodhaka "Atorvastatin" analogues pamusoro wongororo idzi anofanira kudzidzwa nokungwarira.

Kazhinji, chiremba anokurudzira mushonga kuti vaudzewo bioequivalence "Lipitor" uye anoita vane mugumisiro anorondedzerwa zvakabatanidzwa mirayiridzo. Mari "Lipitor" inowanika, hazvina kuoma kuwana, chive vaitire. Zvisinei, izvozvo haungopiwi varwere vane zvivako yaivapo nokuda urema zvakafanana nechirwere. Muchiitiko chino, avo mishonga kuti kungadiwa concessional raitungamirwa Centre bvunzo uye miedzo mukurapa. Kugona kwavo kwakaratidza.

Testimonials pamusoro "atorvastatin"

On kugadzirira "Atorvastatin" Kudzokorora chero murwere haagoni kuva nomazvo, nokuti pasina dzinoongorora lipid Profile zvisingaiti kuzotonga anokonzerwa nemishonga. Naizvozvo, kuti tive nechokwadi kunyatsoshanda, chinofanira kuongorora Kuchinja lipid zvikamu zviduku. Uyezve, chero "Atorvastatin", wongororo izvo zvinowanikwa yakawanda, rinopa mashoko pamusoro nenjodzi. Zvinonyanyozivikanwa sema Migumisiro. Toxicity yakaderera uye kazhinji imperceptible. Zvisinei, chero zvazvingava chitarisiko cytolysis chirwere uye transaminases rwakakoshwa zvibereko zvinoda nokubviswa zvinodhaka.

Varwere vanoti chepfu migumisiro hadziwanzowaniki. Nokuda kwechikonzero ichi, varwere vakawanda akanyeverwa zvinodhaka neshamwari kana hama, kunyange zvazvo kuenda waida zvokurapa kubvunzana, pangozi tinyatsonzwisisa uye Kutsunga zvikamu ropa lipids. Uyewo, vazhinji zvinodhaka chisipo basa ehupfumi Somuenzaniso, kuti anogona kuderedza uremu.

Asi tikanyatsoongorora aifanira kuva hwakanyatsorwisa "Atorvastatin" chinodhaka wongororo. Slimming hazvina zvakakodzera, uye unogona chete kupiwa pachiimbwa zvinorema uye kudya. Combined kushandiswa "atorvastatin" uye dzimwe lipid-richikwidibira nevasori, sezvo iri kazhinji akakurudzira vanhu pasina kurovedza zvokurapa, zvinotungamirira rhabdomyolysis uye chiropa toxicity.

Reviews vanachiremba pamusoro mushonga

On kugadzirira "Atorvastatin" ongororo chiremba kunokosha kupfuura murwere pakudzokorora. Izvi zvinoshandawo zvimwe zvinodhaka. Kazhinji, ivo wongororo abstracts zvose nyanzvi zvaizobatsira kuchengeteka zvinodhaka uye kushanda. It kunoderedza zvachose remafuta akawandisa uye LDL, apo kuwedzera HDL. Izvi zvinokosha zvikuru nokuti kunoita kuti kudzora kukura atherosclerotic Dombo, uye kunonoka kutanga myocardial infarction.

Dynamics hypocholesterolemic chaizvoizvo mukugadzirwa "Atorvastatin" (kudzokorora anenge chiremba nerimwe zvinosimbisa izvozvo) unodoma chaizvo. Normalization kuti serum lipid Profile kunokwanisika mukati 1.5-2 mwedzi. The "rosuvastatin" kunoitwa mukati memazuva 30-50. Zvisinei, nepo "atorvastatin" zvakawanda zvekuchipatara zvidzidzo kutsigira kubudirira kwayo uye kuchengeteka. Kazhinji, izvi zviviri zvinodhaka yakanaka, rimwe nerimwe kungashandiswa kurapa hypercholesterolemia uye prophylaxis zvirwere mwoyo.

Mari zvinodhaka

The mushonga "Atorvastatin" mutengo (zhinji wongororo pamusoro svidelstvo ichi) zvakasiyana zvichienderana mugadziri. kupfuura dzinodhura iri "Lipitor" - chepakuvamba zvinodhaka. Mwedzi kurapwa mutengo uri 900-1100 rubles kana kugamuchira mumwe dose 40 MG. Pamusangano daily chipimo chemushonga 20 MG kurapwa mutengo uri 800-900 rubles. Generic "Lipitor" vari isingadhuri zvikuru.

Mari kurapwa pamwe pamwedzi "Atoris 40 MG" 500 rubles, apo kugamuchira 20 MG - 200 rubles. The "Atoris" - iri bioequivalent "Lipitor" chinodhaka, zvizere vachiitsiva. Kunewo zvinodhaka isingadhuri, "Torvakard" "Lipitor", "Torvas" Mari yaari kunorapwa zuva dose 40 MG kusvika 300 rubles isingadhuri. Uye mutengo kurapa ane zuva dose 20 MG vachava 100-150 rubles.