Alpha-blockers

Alpha-blockers anopira guru uye heterogeneous boka zvinodhaka. Munguva manonwe, kufarirwa zvinodhaka izvi shoma yekudyidzana nokuti kuti, nokuti dambudziko neBP nyanzvi dzakatanga kushandisa thiazide diuretics, ACE FIs. Pakazosvika mangwanani nineties zvakanzi Vakawana kuti Arifa 1-blockers vari kusarudza kuona kwenguva refu (kunyanya kugadzirira "Doxazosin") akafanana tolerability, kuchengeteka, agntigipertenzivnoy basa nevamwe zvinodhaka, iyo chiito inoendeswa BP. Uyezve, mishonga pazvakawanikwa uye zvimwe zvivako kuti kuvatendera taurira varwere vane chirwere cheshuga, prostatic hyperplasia isiri yekenza hunhu, dyslipidemia, mu kuzasi varume uye vatsvaire endarteritis.

Alpha-blockers. kupatsanura

Zvinodhaka zviri rakakamurwa huru mhando mbiri: vanosarudza uye nonselective.

The boka ine nonselective yomuchipatara Arifa 1- uye 2-adrenergic blockers (semuenzaniso, "Fetolamin" gadziriro).

By zvokusarudza kusanganisira mishonga yakadai se "terazosin", "Doxazosin", "Prazosin". Zvinodhaka ari muchikwata ichi kunyanya kukanganisa receptors, izvo riri kumeso tsandanyama kweprostate, dundira mutsipa uye prostatic urethra mugove.

Vamwe mishonga antihypertensive vechigaro mamwe mapoka zvinhu kuratidza zvakafanana ehupfumi sezvo Alpha-blockers. zvinodhaka izvi, kunyanya zvinosanganisira zvinodhaka "Carvedilol".

Kunewo nezvinodhaka, zvivako zvacho zvakafanana avo kuti kuratidza uye beta- Alpha-adrenergic blockers. mishonga iyi, mukuwedzera, vane antioxidant ehupfumi. The mashandiro avo nezvinozoitika kukwikwidzana catecholamines. Kutambura rinoitwa panguva peripheral Arifa adrenergic receptors uye Beta 1-adrenergic receptors. With kushandisa matambudziko zvinodhaka izvi refu anotanga kupera, uye mwedzi inoverengeka gare gare nokupera.

Alpha-blockers vane mikana yakawanda. Zvikurukuru, vane nomugumisiro nenhanho triglycerides uye remafuta akawandisa ari plasma rinobatsira. Izvi zvinooneka kunoderedza mukana atherosclerosis. The mushonga hakuna zvainoita wevasungwa kweshuga muropa, nechepazasi BP pasina kuwedzera kakawanda marwadzo mwoyo. Uyezve, mishonga izvi regai kukanganisa mamiriro potency.

Side migumisiro Arifa-blockers iri zvakakwana diki. "First dose maturo" zvinoshanda zvinokosha.

Zvinofanira akati kuti Arifa-blockers vachikwanisa rokuwedzera uye diki, uye zvakarurama guru nemidziyo ropa. Panyaya iyi, kumanikidza rutapudzo zviri zvikuru wakaratidzwa akarurama nzvimbo murwere, uye zvishoma akazivisa - mune chinjikira. Kana munhu (kuipa) rinobuda kubva pamubhedha, tsinga runogonesa arterial matauriro. Zvakakodzera kuchinja muviri hunyambiri nzvimbo. Muchigamuchira Arifa 1-blockers kudzivisa mudziyo uyu. Pakuita murume akarurama nzvimbo pane rakapinza kuderera kuitiswa. Somugumisiro, uropi anogamuchira okisijeni iri kukwana uwandu. Munhu anotanga rima mumaziso, nzwa dzungu, anogona kuitika yakanyanya simba, mune zvimwe zviitiko, murwere anogona vanowira vanoziya. Apfuudza kubuda (kutora chinjikira nzvimbo) rinowanika mukuvandudza chepfungwa kutenderera. Somugumisiro, kuziva nokukurumidza akadzokera murwere. simba iri, Chokwadi, hakusi pachayo anotakura pangozi zvikuru. Zvisinei, panguva kuwa zvingangodaro kuti murwere anogona kugamuchira pangozi yokukuvadzwa.