"Nebilong": mirayiridzo kushandiswa. "Nebilong": wongororo uye analogues

"Nebilong" kunobatsira zvinodhaka nokuda kurapwa kwezvirwere chokuita zvakanaka mwoyo ushande. Kunatsiridzwa kuita pashure kurishandisa kuti mwedzi mumwe. Pashure Chikumbiro "Nebilonga" normalized kupomba uye BP, vascular kutandara zvasvika, kuti myocardium iri vaipa okisijeni yakakwana. Munenge Muzviitiko zvose zvakanaka pamusana ARV rakaramba kwenguva refu.

Zvinoumba, Kuronga

The mushonga inowanika pamahwendefa. Hwendefa nomumwe anogona ane 2.5, 5 kana 10 MG kuti basa chirungiso. The mushonga unoitwa nokuda nebivolol hydrochloride. Pakati Excipients vaivapo muna Zvinoumba povidone, lactose, magnesium stearate. Zvinoumba vaisanganisa pamwe talc, microcrystalline cellulose, yavaibvisa dioctyl sulfate, colloidal nesilicon dioxide, croscarmellose yavaibvisa, Beta-cyclodextrin.

Pharmacological migumisiro

"Nebilong" mirayiridzo Chinyorwa kuratidzirana senzira ane waro mamiriro enantiomers maviri (L- uye D-nebivolol). D-nebivolol - zvikuru zvokusarudza, yemakwikwi β1-adrenoceptor blocker, L-nebivolol munyoro pamidziyo ropa, anowedzera kuti, iri kukonzerwa imwe kwacho vascular endothelium (kusunungurwa vasodilating vachisiyanisa inzwi chinhu).

Nebivolol kunoderedza BP uye mwoyo zvazvingava, mugumisiro inochengeterwa kwete quiescent ezvinhu asiwo pasi mutoro. Mushure kutora mushonga kumativi uye magumo-diastolic rworuboshwe ventricular zviri akaderedzwa, pane kubatsirawo rimwe mashandiro kuteererwa mwoyo - diastolic. Nekuti pokushandisa "Nebilonga" ejection chakapatsanurwa kunowedzera, vanhu vane IBS akacherekedza antianginal kushanda.

Hypotensive chiito atora mahwendefa "Nebilong" muperekedzi inotsanangura kuderera mubasa renin-angiotensin hurongwa. Antiarrhythmic chiito kunoitwa Akaroromesawo AV-conduction uye kudzvanyirira yakaoma automaticity mwoyo. Ndakabatsirwa hypotensive zvazviri kunoitika mukati memazuva 7-14 yokurapa, kazhinji - pamwedzi. Yakadzikama mugumisiro kutora mapiritsi kuchengetwa pashure mumwe miviri kurapwa.

Pharmacokinetics

The mushonga anwa, anyura zvakanaka, zvichiitika zvakafanana inoshanda pasinei kudya. Muviri ari chiropa uye rinopedzisa paumbwe basa gidroksimetabolitov. Paavhareji bioavailability pashure pokushandisa womukati medicament munhu ane nokukurumidza muviri 12%, nhamba iyi yakakwirira zvikuru pane kunonoka muviri. Sezvo muviri wevarwere kunogona kuitika pamwero yakasiyana, "Nebilong" Chinyorwa rakarumbidza kuti kushandiswa nomunhu wacho zvatariswa muviri murwere. With zvishoma muviri anoshandiswa pasi mishonga yacho zvinodhaka. In nyaya nokukurumidza kupanana zvinhu kunoitika hafu-upenyu maawa anenge 10, mune varwere vane zvishoma muviri, hafu-upenyu yakawedzera 3-5 nguva. Papera mazuva manomwe yokurapa, vanenge 38% vakagamuchira chinodhaka yabudiswa parutivi itsvo, vanenge 48% "Nebilonga" aripo zviri pachituru. The Zvinoumba weti iri shoma mishonga kuchinja - kusvika 0.5%.

umboo

On kushanda "Nebilong" mirayiridzo inogona kushandiswa BP, nokuti Implementation kuti matanho ari varwere CAD (tichibatwa angina) uye nokuda Implementation ari kunzwisisa mishonga mwoyo kukundikana chirwere chimiro.

Treatment pamwe zvinodhaka "Nebilong"

BP

Adult varwere raitongwa 5 MG "Nebilonga", iro unoenderana pahwendefa Pfungwa ndiye dose nezuva. The mushonga inokurudzirwa kushandisa mazuva ose panguva imwe chete. A duku nezvinozoitika kuoneka pashure mumwe maviri vhiki yokurapa, kupfuura akazivisa, iye mwedzi panguva iyo kurapwa rinoitwa. Mahwendefa akakodzera Implementation monotherapy uye kurapwa kwakavakirwa Integrated kushandisa zvinodhaka, izvo vanewo hypotensive migumisiro. Vanhu vanotora "Nebilong AM", mirayiridzo rakarumbidza kuti vawane chimwezve chaizvoizvo kushandisa "Hydrochlorothiazide" pamusoro 12.5-25 MG. kurapwa kwakadaro kukabatanidzwa anogona kuwedzera kuitwa "Nebilonga", asi zvinogona kuitwa chete pashure mekugamuchira zano kupinda chiremba.

Mwoyo kukundikana chirwere chimiro

First chiduku dose pakati medicament, chiremba zvishoma nezvishoma kunowedzera, vakapiwa zvinoitwa murwere. Nokuti pakurapa chakasimba siyana "Nebilong" hakusi kukodzera, mune zviitiko zvakadaro, zvimwe zvinodhaka zvave. Kazhinji kutanga ushandiswe kusvika 1.25 MG zvinodhaka kushandiswa kamwe zuva nezuva, pashure 1-2 masvondo ari dose anogona ngazviwedzerwe 5 MG, uye gare gare - kusvika 10 MG. The daily dose haafaniri kupfuudza 10 MG medicament "Nebilong". Mirayiridzo dzokushandisa inoratidza kuti panguva kutanga kwekupwanyiwa kurapa murwere chakasara pasi pakuongorora kwemaawa maviri pashure ingestion iri pahwendefa, saka kuita mumwe kuwedzera dose nzira. Inosimudzira dose zvingaderedzwa zvakare kana kudiwa ariko.

Kana mwoyo kutadza zviratidzo akazviratidza zvikuru raidudzwa kana murwere kusashivirirana kuti mushonga hurongwa yakawanikwa, kuderedza dose zvinodhaka kana kubereka abolition kwayo. Kazhinji, mwoyo kukundikana, chisingaperi chimiro "Nebilongom" zvakaipa nokukurumidza. Kana kurapa zvainanga kubvisa ezvinhu akadaro, abolition zvinodhaka kuti zvishoma nezvishoma, unogona kuita chiito ichi hasha, nokuti dambudziko anogona yakawedzera. Kana iwe kukanzura zvinodhaka vhiki imwe neimwe inogona kuchiderera dose nehafu. Nokutora mapiritsi "Nebilong AM" mirayiridzo Chinyorwa anotipa mitemo vamwe.

kurambidzwa:

• Renal insufficiency. Chokutanga, nokuti kurapa uchishandisa 2,5 MG zvinodhaka pazuva, kuti dose inogona wakawedzera papera, asi izvozvo hazvifaniri kupfuudza 5 MG.
• Older zera. The kwokutanga dose anogona haapfuuri 2,5 MG kana zvakakodzera, vanomutsirwa 5 MG. Pashure pemakore 65, zvinoda kugara rokuongorora etsvo (rimwe nerimwe vana kuti shanu months).
• Pregnancy. A achangoberekwa anogona kuva zvimwe zvirwere, izvi zvinosanganisira kufema muviri, yomuropa, hypotension, bradycardia, vakadzi saka pamuviri zvinodhaka riri waakaudzwa chaizvo kashoma. Kana mukadzi ane pamuviri anoshandisa "Nebilong" kukanzura rake rotsvakwa kwemaawa 48-72 pamberi pakukurukura. Kana zvisingaiti, achangoberekwa inofanira kuchengetwa kwemaawa 48-72.

Contraindications

"Nebilong H" mirayiridzo Chinyorwa unorambidza kushandiswa zvinotevera nyaya:

• Zera isingasviki makore 18;
• hypersensitivity kuti mushonga zvinoriumba izvozvo;
• bronchospasm, asima (nhoroondo);
• pheochromocytoma, izvo asina kubatwa pamberi;
• metabolic acidosis;
• zvakaoma yokuvamba chiropa chirwere, chiropa kutadza;
• hypotension mune vanhu vane systolic kumanikidzwa 90 mm HG zvichidzika. Article.
• AV-chezvakaipa (I giredhi, III), bradycardia, icho pamwe kwemwoyo zvakafanana 60 bpm. paminiti;
• panguva nokubereka vana, uchiyamwisa;
• chenjera mwoyo kutadza chimiro;
• nematambudziko peripheral kuparadzirwa, pamwe hwakajeka expressiveness;
• cardiogenic kuvhunduka, mamiriro umo zvakafanira kushandisa zvinodhaka isotropic;
• urwere, vanorwara sinus pamwe.

Yambiro inodiwa apo agadza mushonga varwere vane ezvinhu:

• chirwere cheshuga;
• psoriasis (nhoroondo);
• Prinzmetal angina.

nemishonga

In marapirwo rinoreva "Nebilong" mirayiridzo manual, wongororo vanoti ndingangokuvara panowanikwa vamwe nemishonga, izvo richiratidzwa basa zvemwoyo, zvomudumbu uye huta nehurongwa. Zvimwewo kutyorwa - bronchoconstriction maitiro kukanganisa ganda ezvinhu.

Zvokungwarira

"Nebilong" anogona kusimbisa aikanganiswa allergens, izvo vanotyisidzira kukura chakakomba anaphylactic kuita.

Drug kurapwa hazvirevi kukanganisa padanho shuga mumuviri pamberi cheshuga, asi varwere vari boka iri kushandisa mishonga nokungwarira. Sapamazuva cheshuga uye iri hyperthyroidism zvinodhaka kungavanza zviratidzo tachycardia, zvinonyanya raidudzwa nokuda chimbichimbi kushaya mahwendefa.

Kana varwere matambudziko ari kufema ino inoshandiswa "Nebilong" mirayiridzo Chinyorwa anoudza pamusoro ndingangokuvara pfuma constriction of Airways mu COPD. Mukana kubatanidza mushonga nedzimwe zvinodhaka zvinofanira kuongororwa nachiremba wako.

"Nebilong" kunokanganisa kugona kudzinga motokari, kunogona kutungamirira kuneta uye dzungu.

analogs

Zvinokwanisika kutsiva mushonga kuti haabvumiri kushandisa zvinodhaka "Nebilong" mirayiridzo Chinyorwa. Drug analogues zvinosanganisira "Nebilet", "Binelol". By Sevamiririri anosanganisirawo "Nebikor" uye "Nebivator".

Reviews

Sezvo ongororo, mushonga unoshanda kana kushandiswa nemazvo. Zvakakosha kushandisa mishonga uye kutevera zvose chiremba wacho audzwa. The medicament riri basa pamwe contraindications uye unhu murwere, zvichiguma kunobatsirawo. Kuti kurapwa haana kutungamirira kukudziri- nemishonga, unofanira kugara kuongorora mamiriro murwere.