Lupus - chakakomba chirwere

Tiibhii ganda rine kunzwisisa etiology uye pathogenesis. All nezvemarudzi zvina mycobacteria: Avian, bovine, ine utsinye uye munhu. Nokuti munhu anomiririra ngozi chete munhu uye bovine mhando. Kwakadaro ganda maronda - isingawanzowanikwi chakajairika pakati dermatoses, asi munguva ichangopfuura pakave zvakawedzera kuitika.

The zvinhu zvikaita kuti pave chirwere ichi zvinosanganisira: zvirwere tsinga, hormone dysfunction, vhitamini kusaenzana, kukanganisika chicherwa uye mvura muviri, kweropa zvirwere (venous kuzara), murombo okunze uye magariro evanhu, siyana zvinotapukira. Zvinhu izvi kuderedza kudzivirirwa muviri uye vawedzere susceptibility wayo tiibhii mycobacteria. Ivo zvinopfuura Epiderme e nenzira dzakasiyana. Pretty nyore kuti utachiona kubudikidza kukuvara paganda murwere kana zvake.

Pane imwe nzira chirwere. Lupus anogona kuitika kana nayo utachiona chinopinda ganda kana lymphogenous hematogenically kuti tibhii pachoto yaiva nedzimwe nhengo.

In chirwere ichi paganda aonekwa kutapuriranwa granuloma masero ayo vakapoteredzwa lymphocytes. Nokuti iniwo dzinoratidzwa zviratidzo zvakadai caseous necrosis, kuvapo hombe Langhans masero, kuvapo mycobacteria nechepakati chikamu granuloma. Tibhii, tsanangudzo izvo zvinokonzerwa nevanhu histological zvinoda kungwarira kurapwa.

Vakawanda muchimiro lupus. lupus kwakadaro, izvo dzinoratidzwa kubudikidza panowanikwa akapfava zviratidzo chaizvo hillocks (lyupom) kuva vaaleanpunainen ruvara hwakajeka pokugumira (kusvika 3 mm) ndiyo Inonyanya kubata vakadzi. Lyupomy muri rwarisa granuloma. Vanokura batanidza, uye ipapo pane chakasimba foci (sandara chimiro). Zvishoma nezvishoma lyupomy fibrosing. Panguva iyi, iyo vanga atrophy. Panewo rudzi peptic urikanwi chirwere, iyo pane exudative muitiro uye lyupomy ulcerate. Pane zvachero nemaronda ropa nyore chete gogonera, nyoro kumicheto. Panewo siyana bundu uye verrucous lupus. Kazhinji, munhu mapundu rinowanikwa kumeso, asi anogona iri kumwewo. Kazhinji kunokanganisa mucous Kamudzira dzokudenga, matadza, miromo, uye mhuno. Anonyadzisira lupus vane kuyerera refu uye usimbe. Kana pangava yematambudziko pamwe kukura lupus-carcinoma.

Kollikvativny lupus - wechipiri ndicho chimiro chirwere nyaya. The kwemakomo vari maloboleznennymi, gobvu, riri yakadzika dermis uye kukura nokukurumidza MUBHUKU dzakabatana. Vanogona kuwana dhayamita 5 cm. The ganda pamusoro nodes ane rinokwanisa kucheneruka tint. Nokufamba kwenguva, mashoko nodes vari kurigamuchira pane pute kuchitonhora, pashure yavakanga dzinopaza pakabudiswa ne kugutsikana. At nzvimbo nodes vari vakaumba nemaronda munyoro kumicheto. Aporeswa urikanwi mavanga vakasara ane mugari chimiro. Kakawanda inokanganisa pamutsipa, dzinenge - pabazi.

Indurativny lupus, maronda miliary, lichenoid, warty, papulonekrotichesky vari yechipiri siyana tibhii, kubva kutanga tikafunga mamwe foci chirwere vakamboratidza arwara nechirwere vanhu.

Primary siyana hadziwanzowaniki, nokuti kubaya pamusoro vachangoberekwa pari kuitwa. The chirwere kupfeka anamnesis data, chiremba mufananidzo, migumisiro tuberculin nemiedzo, tsika uye histological kuzviongorora.

In chirwere chakadai, akadai tibhii ganda kurapwa ipfupi kune anotevera: tuberculostatic mishonga, dzekugonesa kutapata, kuvandudza metabolic pezvakaitwa. By tuberkulostaticheskoy zvinodhaka zvinosanganisira isoniazid, protionamid, streptomycin, pyrazinamide, rifampicin, ethambutol, florimitsin, kanamycin.