Leptin inoderedza (hormone) akatsigira - zvinorevei? Leptin inoderedza - hormone saturation: nerevane kwayo basa

Around 2011 World Health Organization, vaongorori vakatanga kuteerera dzingangovapo kuti kufutisa. Kubvira panguva iyoyo, zvinoita vakatotanga kuwana zvakawanda zvaidiwa denda, uye kufutisa vava pasi kunyange vana. Makore mashomanana akanga apfuura, masayendisiti vakanga vawana leptin inoderedza - hormone kuti ndiye anokonzera kunzwa mukaguta uye zvinogona kushandiswa pakurapa chirwere ichi.

A divi mugumisiro tsvakurudzo parabiosis

Nhoroondo kuwanikwa ichi kemikari unesungano pamwe kutsvakurudza pamusoro American musayendisiti Hervey, aifarira pezvakaitwa parabiosis. Izvi zviri zvipenyu ezvokunambira kunze kwomuviri waamai splicing mhuka mbiri uye dzimwe nguva matatu. Panguva iyoyo vakanga vakamisa chimwe kweropa maitiro uye node. Research iri mhando zvaikoshawo kuti kudzidza kukurukurirana pakati hormone uye spliced tishu.

The musayendisiti akafarira kurondedzera kwazvo mitambo yose hypothalamus. Sezvo kazhinji zvinoitika zvesayenzi, pakati nyaya iri kosi yake tsvakurudzo mukaguta kemikari leptin inoderedza yakawanikwa. Nechekare ne 1998, nyaya iyi yakabudiswa 600 nyaya.

Ndezvipi mashandiro anoita leptin inoderedza pamuviri?

Translated kubva mutauro wechiGiriki zita rake rinoreva "tetepa, simba." Zvisinei, wokupedzisira shoko hazvigoni kunzi. Pashure pezvose, basa rake muviri chaizvo. Leptin inoderedza - hormone rinopiwa munhu muchikwata chaiye zvinhu anonzi adipokines. Kusiyana nevamwe mahormone, ivo anobudiswa havasi nhengo yacho kwemakemikari anobudiswa hurongwa, uye adipose tishu. Adipokines mumuviri vari informational ushande. Somuenzaniso, leptin inoderedza anokwanisa nekufambisa mashoko kuti hypothalamus pamusoro zvikuru sei kana zvishoma pane mafuta aiva mumuviri pashure ingestion. Uyewo hypothalamus inodzora chikafu yaunodya - kunowedzera kana zvinoderedza havi.

Leptin inoderedza mabasa haagoni kurerutswa. Zvinokurudzira Nzara kudzvinyirira, kunowedzera thermogenesis pezvakaitwa, i.e. mafuta shanduro kupinda simba ndiEzekieri. Leptin inoderedza rinobatanidzwa kugadzirwa dopamine. In hadzi muviri leptin inoderedza unochinja Nguva kumwedzi. Rinotaurawo anovandudza kushanda yose hadzi dzokubereka nadzo yose. Uyezve, peptide ichi chinodiwa dzekugonesa kutapata.

Leptin inoderedza Anoshanda pedyo pamwe chete hypothalamus. Kana munhu unopisa zvokudya, zviri hypothalamus naro anogamuchira anonongedzera kuti anokonzera kunzwa zvizere. The ukama leptin inoderedza uye dopamine sezvayakawanikwa nemasayendisiti kudaro kare. Zvino pane mazano kuti mufaro uye vanoda chokudya, pane nokuda kushaya dopamine uye leptin inoderedza panguva imwe chete.

Leptin inoderedza mumatunhu uye munhu dzemunharaunda

leptin inoderedza tsika inogona kusiyana zvichienderana vari imwe zera boka. Uyewo, uwandu leptin inoderedza anogadzirwa kunoenderana chechikadzi. Asati kutanga kuyaruka vari vakomana nevasikana vanenge zvakafanana leptin inoderedza. Zvadaro zvinhu anochinja zvikuru. Sezvo pane nguva dzose zvakawanda hadzi muviri mafuta rinenge riri leptin inoderedza mumatunhu uye pakatanga kuyaruka pavasikana riri kumusoro. Uyewo pane chakarurama ichi sei inonzi estrogen.

The Zvinoumba kemikari

Leptin inoderedza - hormone kuti kugadzirwa kwayo ane peptide. Zvinosanganisira 167 zvinhu - amino asidhi residues. Zvakawanda kemikari ichi zvinoberekwa mafuta masero zvakananga. Zvisinei, kunze izvi unogona kubereka dzimwe marudzi masero. Kureva, placenta, mammary epithelium, gastric mucosa, skeletal tsandanyama.

Yakakwirira kwevari leptin inoderedza sechinhu chinoita kuti coronary tsinga chirwere

Zvisinei, zvose pasi uye yakakwirira kwevari mahormone zvose zvine kunambwa mumuviri. Izvi zvinoshandawo leptin inoderedza. Kemikari upgraded - zvazvinoreva uye kuti zvingaita nhamba iri muviri? Chokutanga, mukuru wevakuru leptin inoderedza chinhu chikonzero ngozi zvirwere zvakasiyana-siyana. Somuenzaniso, vakawedzera leptin inoderedza chinokurwadzai kuwedzera pamusoro longitudinal zvinyama uye deposition kuti munyu siyana mune midziyo ropa, inotungamira CHD.

Leptin inoderedza uye chirwere cheshuga

An kusaenzana kwezvinhu leptin inoderedza kwakabatana nezvirwere zvakawanda. Mumwe mugumisiro ngozi kukundikana mubasa rake cheshuga. chirwere ichi chinowanikwa kubva ichangopfuura, vanachiremba, chaZekariya pamusoro kemikari leptin inoderedza. Ndiye anokonzera chii, kuti peptide muchiitiko ichi? Muvanhu utano, leptin inoderedza kunowedzera uwandu shuga goho maererano nechitarisiko miviri. Uyewo hazvina akazoita kwetunhu jekiseni iri rwatata. Kana muviri yakawanda leptin inoderedza, inova mhosva generating yakawanda jekiseni. Kunosimbisa muviri aikanganiswa jekiseni uye leptin inoderedza. Kemikari rakakwirira vaya vari majini vafanorongerwa kana kubatwa zvimwe zvinokonzera njodzi anokonzera chirwere cheshuga.

Kudyidzana nemumwe peptide kemikari

Mumwe mukuru "shamwari yake inomubatsira" pakati leptin inoderedza mu murau kudya maitiro ndiwo "nzara kemikari". Leptin inoderedza uye ghrelin (vakadanwa saka kemikari) anosangana mumwe nokuita zvakasiyana basa. Ghrelin chinokonzera kutekenyedzwa nenzara uye woutsinye pakarepo pashure zvokudya. Recently zvikazikamwa kuti peptide uyu zvinosimudzira kufuta pakupedzisira. Sezvazvakanyorwa kubudiswa dzakakwirira kwazvo panguva zvinhu zvinoshungurudza. Ndokusaka pashure kukurukura refu saka vanoda chokudya.

Sei kuzvibata zvokudya leptin inoderedza. Kemikari uye kunzwa zvizere

Zvinosuruvarisa vakawanda mafeni ose zvokudya zvinofanira raanotaura mirau iyi pasina zvakakodzera tinyatsonzwisisa zvose zvinogoneka njodzi kune muviri. Vazhinji zvokudya mishonga ine kwakaderedza azvipire kudyiwa makabhohaidhiretsi uye mafuta ari Exchange zvinotora chinoshingaira chikamu leptin inoderedza kemikari. Ndiye anokonzera zviri pamberi musikana ose kana mukadzi uyo asingafungi akasarudza kugara yakaoma kudya Somuenzaniso, anozivikanwa ne "Kremlin?" Huru ngozi inobatanidzwa metabolic zvirwere. Pashure pezvose, zvokudya kunosanganisira chinokosha kukamurwa iri kudyiwa makabhohaidhiretsi. Uyezve, kana kushanda wakarambidzwa mafuta, uye anogona kutungamirira zvakasiyana-siyana kwemakemikari anobudiswa zvirwere.

Vakawanda vakanzwa kuti pashure zvokudya kurema anogona kudzoka, uye kunyange mukuru pamwero. Izvi imhaka yokuti uropi ndoda kutanga kupindura leptin inoderedza. Nemamwe mashoko, pashure zvakaitwa izvi hypothalamic leptin inoderedza anova kakawanda rezasi. Munguva ichangopfuura, mukadzi akaondoroka achiri kuramba kunzwa nzara semubairo yokuwana zvakatowanda uremu. Mukuwedzera, uropi kugamuchira pakutanga kudya yakakwana nhamba anonongedzera ari panowanikwa "nguva nzara" anopa murayiro kupedzera sezvo shoma simba sezvinobvira. Saka, mutambo muviri kwakaoma chaizvo - kana kazhinji musikana uchatanga kurarama ndakagara mararamiro.

Pane pfungwa kubva zvokudya?

Zvechokwadi, muna muitiro kurasikirwa uremu, unogona kurasikirwa yakawanda mafuta muviri, uye panguva imwe chete ari kumbonyanya pfupi. Zvisinei, mapopoma uye leptin inoderedza. Kemikari upgraded - zvinorevei kuti munhu ari kuenda kuenda kudya? Ungangove, ayo pamwero iri yekudyidzana kutura muvhiki yokutanga. Siya uye mafuta - asi zvine musoro kana uropi anorasikirwa kukwanisa kunzwa nzara uye nguva ezvinhu "chimbichimbi"? At okuparadza kuramba leptin inoderedza zviri nyore chaizvo kuwana uremu pamazuva okutanga pashure zvokudya.

Vanhu vanotambura kufuta kana kufutisa, pamwe nguva zvinovawo zviome kuderedza uremu. Pashure pezvose, muviri wavo anova haanyanyi leptin inoderedza. With wadya vanofanira kudya zvakawanda, sezvo uropi dzavo kare anenge handifaniri kuti saturation kemikari nechokwadi chokuti muviri nenzara. Leptin inoderedza - hormone saturation - haizorambi navo sezvo vakadaro.

Nzira nepakati leptin inoderedza uye ghrelin

The chete nzira yokubuda ichi utsinye denderedzwa - kuita Kurovedza muviri. Izvi zvichabatsira kuti zvishoma nezvishoma chidzosai hypothalamic leptin inoderedza wanda. Uyewo, nzara kemikari ghrelin unobva kuna chakaipa. Ongororo dzakaratidza kuti kunyange hafu yeawa Kurovedza muviri kunobatsira kuderedza wevasungwa kuti ghrelin muropa. Saka, zvikuru muviri kunobatsira ndeyokubvisa zvakawandisa mafuta uye kuderedza havi.

Nokuti zviri nani kudzora leptin inoderedza uye ghrelin mwero mumuviri, vaongorori kupa zano inotevera. Chekutanga, unofanira kugara pedyo yakaoma zuva nezuva - kuenda kunorara kumativi gumi o'clock usiku simuka pa nhanhatu ari mangwanani. Chechipiri, tinofanira kubata kuchaja mangwanani ose, kana zvimwe muviri chaiko. Kunyange duku muviri usina chawadya, sezvo netsvakurudzo, kunobatsira kuvandudza aikanganiswa jekiseni uye shuga. Uye ichi ndicho - yakanaka nzira kudzivirira chirwere cheshuga.