"Glibenclamide": mirayiridzo kushandiswa, kusunungurwa chimiro, photo, analogs

Chii mushonga "glibenclamide"? Mirayiridzo yokushandisa, kusunungurwa chimiro, analogues zvairatidza vaitarira zvinodhaka dziri pasi apa.

Zvinoumba, kavha, chimiro kusunungurwa vamiririri

In chii chimiro anoitwa mushonga "glibenclamide"? Guide inoshuma kuti chokushandisa anogadzirwa muchimiro mahwendefa iyo inoiswa epurasitiki midziyo (kurondedzera muchitokisi) uye bhokisi rakagadzirwa makadhibhokisi, ukuwo.

The Kuronga mushonga pasi kukurukurwa zvinosanganisira 5 MG glibenclamide uye ebetsero zvinhu zvakadai mbatatisi starch, lactose monohydrate, magnesium stearate, yavaibvisa croscarmellose, indigo Carmine E 132 Colloidal nesilicon yakasviba 25, uye povidone.

Drug chiito

Chii chinodhaka "glibenclamide"? Mirayiridzo Use inotaura kuti ichi zvinoreva nedzokunze hypoglycemic kushanda muna vanhu utano uye varwere cheshuga kuti mhando II.

Kubudirira zvinodhaka izvi nokuda kwayo kukwanisa kuwedzera jekiseni secretion pamusoro pancreatic Beta masero nokuda kurudziro yavo. Maererano nenyanzvi, mugumisiro uyu mushonga kunosimudzirwa pasi pokudzora shuga.

Kinetic inoratidza imwe nomumukanwa Pfungwa

Zvii zviri yo pharmacokinetic zvinodhaka "glibenclamide"? Mirayiridzo dzokushandisa Inoti kuti pashure nomumukanwa dosing mahwendefa yezviri fuma nokukurumidza uye akapotsa zvachose wefodya kubva zvomudumbu turakiti.

Mawa chikafu yaunodya kunotungamirira kuti rutapudzo pamusoro glibenclamide wevasungwa munguva plasma (tichienzanisa usina chawadya). Kubatana kwakaita chikamu ichi chete sealbumin kwazvo 98%.

Murwere chiropa glibenclamide iri dzikwanise zvinotevera metabolites: 3-Kishi-hydroxy-glibenclamide uye 4-mhiri-hydroxy-glyburide. Ndivo goho yakafanana papi kubudikidza netsvo uye pamwechete mutsvina yadzo.

Zvichakadaro kubviswa hafu-upenyu zvinodhaka ndiko maawa 2-3.5. In vanhu vane havachanyatsogoni chiropa basa, nhamba iyi yekudyidzana ipfupi.

Zvairatidza kuti kushandiswa kwezvinodhaka

Mune zvimwe zviitiko, murwere mapiritsi "glibenclamide" unogona kupiwa? Izvi zvinoreva vanokurudzira kutora varwere cheshuga kuti mhando II, apo pasina mukana kuripa hyperglycemia kuomesa kudya uye kurovedza muviri, kana uremu.

Kurambidzwa kushandiswa

Pane contraindications iri zvinodhaka "glibenclamide"? Mirayiridzo Use inotaura kuti chivako ichi rirege raitongwa varwere vane:

• nyanya Unopisa;
• Hypersensitivity kune basa zvinoriumba, uye thiazide diuretic kana sulfonamides;
• ketoacidosis;
• chirwere cheshuga pakoma prekomatosnoe inoti;
• Kugadzirwa yomuropa;
• Kuvhiya nezvimwe kunotevera;
• gastroparesis uye intestinal mhingaidzo;
• pamuviri;
• chirwere cheshuga wokutanga mhando;
• achiyamwa.

Medicament "glibenclamide": mirayiridzo kushandiswa

Yakakurukura mushonga anofanira kuzviita chete nachiremba ane ruzivo. mushonga uyu anofanira kugara pamwe vaitofanira kudya. Chete iyi zvakafamba tichabudirira. ayo chipimo chemushonga zvinoenderana nokushivirira pakuongororwa (ropa shuga yomuropa, zviratidzo zvinobva weti, etc.).

Saka sei kutora zvinodhaka "glibenclamide"? Zvipatara zvinoreva kuti kutanga shoma mishonga. Izvi ndezvechokwadi kunyanya vanhu vane tsika yomuropa uye uremu muviri asingasviki 50 makirogiramu.

Kazhinji, asi dose of medicament wokutanga 0,5-1 hwendefa pazuva. Izvi anoenderana 2.5-5 MG vanoshingaira chirungiso. Kana va neudhadha mushonga chiito yakanatsa nhamba zvinogona kuwedzera zvishoma nezvishoma kune mapiritsi matatu pazuva, zvakafanana 15 MG kuti basa chirungiso. Izvi zvinofanira kuitwa pane zvikamu ane mazuva mashoma kusvikira vhiki imwe, kusvikira zvinodiwa mugumisiro kunokwanisika.

Sei uchatamisa murwere mumwe mushonga ari mushonga "glibenclamide"? Kushandiswa mishonga iyi yaifanira nokungwarira zvikuru. Chokutanga, murwere ushandiswe mahwendefa maawa 0.5, uye ipapo zvishoma nezvishoma nokuwedzera dose kuti zvikuru.

Varwere vakwegura uye zvamuremadza kana varwere zvokudya zvinovaka muviri uye havachanyatsogoni chiropa kana itsvo basa zvitsigiso kana kutanga chipimo chemushonga mishonga iri aida kurerutsa mukana wokuti kukura yomuropa. Uyewo kusarudza zvakarurama dose zvinodhaka inofanira kuva kudzikira muviri uremu kana apo kuchinja ayo netsika mararamiro.

A nzira pakugamuchira hypoglycemic piritsi

Sei kushandisa zvinodhaka "glibenclamide"? Mirayiridzo yokushandisa (nepikicha zvinodhaka riri munyaya ino) rinoti aiona hwendefa zvinofanira kutorwa pamberi zvokudya girazi yakasvinwa mvura uye pasina kutsenga.

Pamusangano daily chipimo chemushonga 2 mahwendefa, Zvinokurudzirwa kuti zviparadzanise medicament muna 2 yakakamurwa mishonga (mangwanani uye manheru) ari nhamba 2: 1.

Zvinokosha kushandisa mushonga uyu panguva imwe chete. Uchisiya mabiko Hwendefa Pfungwa wakarambidzwa akatorwa pamwe zvinotevera.

Ya yokurapa pamwe mumiririri uyu kunobva chirwere. Mumazana yawapiwa kunodiwa kuti tiite kuramba richiona nezvezvabuda murwere mamiriro exchange zvinhu.

nemishonga

The medicament "Glibenclamide" analogs zviri pasi apa, anogona kukura wanda zvisingadiwi kukanganisa huta, kwemakemikari anobudiswa, peripheral uye zvomudumbu hurongwa uye hematopoietic. Panyaya iyi, murwere anogona kuratidza yaivhuvhuta zviratidzo zvakadai kuda kurutsa, yomuropa kunosiyana zvakaoma kwazvo, hepatic dysfunction, manyoka, nomusoro, cholestasis, simba, dzungu uye kuneta.

Zvinofanira kucherechedzwa kuti yaunodya ari mudziyo asingadi haabatanidzi chitarisiko dermatological uye neutachiona sezvo photosensitivity, kuvaviwa, ganda mapundu uye mamwe mamiriro zviratidzo.

Ovhadhozi zviitiko hypoglycemic vamiririri

Chii Zviratidzo kuitika apo yepamusoro mishonga mishonga "glibenclamide"? Manual inoti kuti ovhadhozi, murwere anogona kuva yomuropa, zvimwe achiperekedzwa muutera, kunzwa nzara, nomusoro, kufunganya, kunyanya vangadikitira, dzungu, tsandanyama tremor, palpitations, kuzvimba muuropi, chiratidzo uye kutaura zvirwere.

Mabatiro ezvinhu akadaro zvinoda kukurumidza kubvuma shuga-digestible chikafu. Somuenzaniso, muchero muto, shuga, chibage manyuchi, chinonhuwira inopisa tii kana uchi.

Muzviitiko zvakaipisisa, murwere chinotarisirwa 50% shuga mhinduro, "Dextrose" "Glucagon" kana "Diazoxide". Zvinodawo chaiyo kudzora glycemia, creatinine, urea senitrogen, electrolytes uye kusarudza ph.

Kudyidzana nevamwe vanachiremba nzira

The ibatanidzo vaiona zvinodhaka pamwe Anti-systemic zvinodhaka, tetracyclines, fluoroquinolones, chloramphenicol, Mao FIs, uye ACE, H2-blockers, "clofibrate" Beta-blockers, probenecid, bezafibrate, "paracetamol", anabolic steroids, ethionamide, allopurinol, pentoxifylline, cyclophosphamide "reserpine", jekiseni uye sulfonamides anokwanisa potentiate yomuropa.

Pamunhu yaizoshanda panguva kushandiswa mishonga pamwe phenothiazines, thyroid uye glucocorticoid mahormone, barbiturates, estrogens, diazoxide, progestins, glucagon, lithium munyu, Adrenomimeticalkie zvinoreva saluretikami nicotinic asidhi uye nomukaka aigona simba rayo hypoglycemic kushanda.

Formulations vakadaro acidified weti (kusanganisira Ammonium chloride, karusiyamu chloride, ascorbic acid), anogona kuwedzera Zvakaitwa vaiona medicament.

Kushandiswa "glibenclamide" ne "rifamycins" Inowedzera inactivation uye kuderedza kubudirira aimbova.

chaicho mashoko

Hypoglycemic mumiririri dzinofanira kuzokurukurwa nokungwaririra varwere kutambura kubva renal dysfunction uye chiropa, uyewo pathological ari thyroid uye adrenal omumuviri, febrile ezvinhu uye chisingaperi chidhakwa.

Kuti aite chakaipa kurapwa zvinoda kugara richiona ropa shuga kwevari murwere, uyewo yaro excretion.

Kana kudya mishonga murwere hwapedyo yomuropa, shuga yakatarwa mukati (panyaya kana munhu anoziva). Kana chavanoziva, shuga chinotarisirwa nomutsinga, uye glucagon - subcutaneously, intramuscularly kana nomutsinga. Mushure murwere anopepuka, achaita pakarepo kupa zvokudya, akapfuma makabhohaidhiretsi, kuitira kudzivisa mumwe dzokororo ine yomuropa.

Kwaunoita uye analogues (anoreva zvakafanana) rinoreva

Select analogs zvinodhaka uku kunofanira chete kuva ruzivo nyanzvi. Nokuti vanachiremba vakaita zvinodhaka zvinosanganisira zvinotevera: "Manin", "Manin", "Maniglid", "Betanaz" uye "Antibet".

Zvinofanira kucherechedzwa kuti Pharmacies kazhinji kutengesa anoreva zvakafanana pamusoro chokushandisa ichi. The inonyanya kushandiswa kwavari, "Glidanil", "Glibeks", "Glibamid", "Gilemal", "Glibomet", "glibenclamide". The chipimo chemushonga mari idzi anosarudzwa nomumwe.

Kana mutengo "glibenclamide" chinodhaka, izvozvo zvinosiyana iri kuwanda 280-360 rubles.

Reviews emishonga

Zvino munoziva kuti ndiyo mushonga "glibenclamide". Mirayiridzo kushandiswa, uye chimiro analogues nzira pamusoro apa.

Zvavanotaura nezvazvo zvinodhaka vanoshandisa? Kazhinji, mashoko ose pamusoro payo vari kuderedzwa kukurukura nevaya kana zvimwe kuchirapa regimens kuti pachii vanhu vane chirwere cheshuga.

Vatengi vanoti kuti kazhinji "glibenclamide" yaishandiswa monotherapy. Kunyange kune vaya varwere vari ushandiswe mushonga akabatana nevamwe zvinodhaka hypoglycemic.

Maererano vanachiremba, kugadzwa mushonga pasi kufunga kunoda munhu kusvika. Panyaya iyi, nyanzvi anofanira kuziva zvose migumisiro Analyses, uye zvimwe zvidzidzo. Tora "glibenclamide" varwere panguva nokungwara wavo ngozi kwazvo utano uye upenyu.