"Dobutamine": mirayiridzo kushandiswa, kusunungurwa chimiro, chipimo chemushonga, wongororo, analogues

Zvinetso nemidziyo ropa uye mwoyo zvakawanda mune vanhu vakwegura. Asi kazhinji zvirwere zvakadai simuka uye varwere zvikuru vaduku. Kuti uvandudze ezvinhu omurwere, vanachiremba kazhinji mishonga cardiac zvivako. Mumwe wavo ari chinodhaka "Dobutamine". Mirayiridzo kushandiswa, kusunungurwa chimiro, analogs uye zvivako zviri vakati zvinodhaka dzinoturwa pazasi.

Zvinoumba, kavha, zvinodhaka chimiro

The medicament "Dobutamine", mirayiridzo kushandiswa iri rinotanga svinga gobvu bepa, chine fuma sezvo dobutamine hydrochloride, uye siyana anotsigira zvinhu.

In yavakatengesa zvinodhaka anouya muchimiro Hauoneki kana zvishoma yellowish läpinäkyvä mhinduro kuti aizomupa, kuti anoiswa mukati girazi ndiro.

Uyewo, mushonga uyu zvinogona kutengwa muchimiro Ndinoda-kuomeswa chigadzirwa uye pfungwa kuti mhinduro.

The pharmacodynamic ehupfumi ane injectable mhinduro

Chii chinodhaka "Dobutamine"? Mirayiridzo dzokushandisa (ampoules mushonga ichi inogona kutengwa chero chezvinodhaka) inoti kuti cardiotonic, munhu chakaita zvokugadzirwa catecholamine uye Beta-1-agonists.

mishonga iyi anokwanisa inotokonya Beta-1-adrenergic receptors ari myocardium uchiwedzera contractility kwayo. It kunowedzerawo paminiti, uye sitiroko Vhoriyamu mwoyo uye ropa midziyo kunoderedza Ops.

Pashure kushandiswa kwezvinodhaka ichi wakakonzera mwero kuwedzera kwemwoyo. Chronotropic mugumisiro zvinodhaka, uyewo zvakwakanakira dromotropic kwakabatsira akaratidza panguva dzakakwirira dosages.

In nepakati mishonga, mushonga uyu zvakaneta kunokanganisa kweropa. Nokuti iye ane runako pfupi hafu-upenyu, chinofanira kupiwa dzose. Asi zvinofanira kurangarirwa kuti kuramba kurapwa pamwe zvinodhaka ichi kwemaawa 72 kana kupfuura hunoita kuti muropa.

Shandisa medicament "Dobutamine", mirayiridzo kushandiswa inorondedzerwa pazasi, zvinokosha kudzora munhu mawa unonzi, electrocardiograph, mwoyo mwero uye BP.

Kinetic parameters of medicament

The mushonga "Dobutamine" Zvinoda kushanda kwenguva yakareba sei? Mirayiridzo dzokushandisa (mahwendefa - siyana mishonga yakadaro hamuna) rinoshuma kuti pashure intravenous aizomupa zvinodhaka maturo ari kuchengetwa pashure 2 maminitsi. arambe achirema yake mudanga kunyange pashure ¼ awa kunowanikwa mune plasma.

The hafu upenyu zvinodhaka ndiko maminitsi 2-5.

Zvairatidza kuti kushandiswa kugadzirisa

Waizviziva here kuti mune dzimwe nguva, basa zvinodhaka "Dobutamine"? Mirayiridzo yokushandisa maererano zvinotevera zvairatidza:

• chenjera mwoyo kutadza;
• pulmonary edema;
• CHF decompensation (sezvo kwenguva pfupi anotsigira nzira);
• ungaderedza cardiac goho;
• achiitisa kushushikana echocardiography (nokuti kuongorora chirwere).

Contraindications pakushandisa zvinodhaka

In chii Muzviitiko regai taurira munhu cardiac mumiririri, se "Dobutamine"? Mirayiridzo dzokushandisa (zvinodhaka analogues dziri pazasi) rinoshuma zvinotevera contraindications:

• zvokuimba mhingaidzo kana water drainage ropa kuzadza mwoyo ventricles (semuenzaniso, obstructive cardiomyopathy, kutsemuka stenosis, akaratidza cardiac tamponade) ;
• giperuvstvitelnost kune huru chirungiso;
• hypovolemia;
• Mao FIs.

Drug "Dobutamine": mirayiridzo kushandiswa

Vachangoberekwa, mushonga uyu rinoshandiswa kuti anokosha anoratidza. Izvi zvinoshandawo vana zviduku zera.

Uyewo analogs zvinodhaka ichi, "Dobutamine" iri dzaizopiwa intravenous yaitonga. Saka kare rakasanganiswa Ringer mhinduro, 5% shuga kana yavaibvisa chloride.

Agadzirira mushonga chitoro hapana kupfuura zuva. Kumhanya uye nguva chourongwa kunobva hemodynamic parameters. Panyaya iyi nekuda murwere nemamiriro kunoda nguva zvichiongororwa. Zvakakodzera akuteerere kwemwoyo, BP kukosha, uye cardiac goho (kana zvichibvira).

Saka chii chipimo chemushonga iri ushandiswe "Dobutamine hexane?" Mirayiridzo dzokushandisa yakashuma kuti mukuru vanhu nayo chinotarisirwa mune imwe mari 2.5-10 MG / makirogiramu / Maminitsi (mu zvisingawanzoitiki kacho -. 40 ug / makirogiramu / Maminitsi). Pamusoro vana, ivo zvinodhaka dzakabatwa vari dose pamusoro 1-15 mcg / makirogiramu / min.

Marwadzo panguva kurapwa pamwe mushonga

Maitiro api asina kunaka anogona zvinodhaka "Dobutamine"? Mirayiridzo yokushandisa kutaura pamusoro zvichibvira panowanikwa zvinotevera migumisiro:

• kuvaviwa, angina pectoris;
• bronchospasm;
• mapundu, palpitations;
• tachycardia, chills;
• phlebitis panguva jekiseni nzvimbo;
• cardiac arrhythmias (ventricular fibrillation arrythmia);
• kuwedzera systolic BP;
• kuda kurutsa, nomusoro.

All kukunakira kubudikidza mwoyo uye ropa midziyo zvinosiyana zvichienderana chipimo chemushonga zvinodhaka. Kunowanzosanganisira inonyangarika pashure kumbomira pakati aizomupa, kana pamwe vasanyanye kwayo nokukurumidza.

Price uye zvakafanana mishonga

How zvikuru "Dobutamine hexane?" Mirayiridzo dzokushandisa haapi mhinduro yomubvunzo uyu. In Pharmacies, mutengo zvinodhaka izvi zvingava anenge 350-450 rubles.

Chii chinofanira kufungwa kutsiva mushonga? dzomuzana ake ndeizvi zvinodhaka: "Dobuzhekt", "Dobutamine Solvay", "Dobutamine Giulini", "Korotrop", "Dobutamine Lachema", "Dobutamine Nycomed".

Reviews nyanzvi Mishonga

Consumer wongororo of vaiona gadziriro kwete. Izvi imhaka yokuti vakadaro cardiotonic vamiririri kushandiswa chete zvashata ezvinhu (semuenzaniso, rikwanise mwoyo kukundikana, kana mapopoma cardiac indekisi uye kuderedzwa rworuboshwe ventricular contractile basa). Kazhinji, izvi ezvinhu ari kuchengetwa cardiomyopathies, septic kuvhunduka, myocardial infarction, uye kuvhiya mwoyo yakazaruka.

Maererano nezvokurara, mishonga anoonekwa nheyo pharmacological mishonga cardiogenic kuvhunduka. Hazvina kushandiswa pakurapa chirwere chemwoyo.

Nokuda kuti mishonga iyi inogona kukonzera arrhythmia uye tachycardia, inofanira kutevedzerwa mukati pfupi nguva uye bedzi Muzviitiko zvakaipisisa, kureva mukati rikwanise mwoyo kukundikana.

Hazvibviri kuona chokwadi chokuti chinodhaka ichi zviduku siyana pakati ine chepfu migumisiro uye dzokurapwa mishonga.

Kusiyana zvinodhaka "Dopamine" Haana haambokonzeri vasodilatation.