Cushing kuti Syndrome Cushing: Zviratidzo uye kurapwa nzira

Kokutanga nechirwere chakadai, akadai Cushing kuti chirwere paakarondedzerwa 1924. Pioneer akava wetsinga of Soviet Union Nikolay Itsenko. Akataura kuti urwere pakati chikonzero chiri atadze kushanda zvakanaka nezvevamwe zvikamu uropi iri huta uye kwemakemikari anobudiswa gadziriro, yainzi hypothalamus. Zvadaro tsvakurudzo muna Amreke apo musayendisiti Cushing akaratidza maonero kuti kukundikana uropi basa imhaka kuti pituitary bundu. Modern kuongorora kwakaratidza kuti veracity ari mhedziso sezvo pituitary, uye chirwere Cushing kuti Ndokusaka akapiwa zita - "chirwere Cushing kuti".

Kazhinji, chirwere kunoitika nokuda kuparadzana kemikari inonzi corticosteroid kuti anosunungura ari adrenal shwanu. Sezvaratidzwa, zvinonzi chirwere mushure kuonekwa ari adrenal anomera kana dzimwe nhengo dzomukati, somuenzaniso chiropa, Árbol kana pancreatic kenza. Pangozi kazhinji anopinda hadzi hafu yevanhu munguva boka kubva 25 kusvika 40 makore. Chikonzero ndechokuti pituitary bundu (huru mhaka chirwere) rinowanikwa kakawanda vakadzi pane varume 5 nguva. Asi pane zviitiko nechitarisiko chirwere ichi, uye vana, uye vakwegura.

Danger kushandisa yakawanda steroids, kunyanya pavanenge kushandisa zvakakwana kwenguva yakareba, sezvo basa kemikari anogona Activate Cushing kuti syndrome. Uyewo namarudzi ngozi visceral anomera inochinja kugadzirwa kemikari cortisol. Apo neapo chirwere chinogona kuitika nokuda magene kubatwa.

chirwere ichi chakakomba zvikuru uye kunyange ngozi upenyu hwevanhu, asi kuti vahwine ingangodaro kuonga yazvino. Muitiro kurapwa uye kupora achatora nguva, pamwe kunyange kusvika makore anoverengeka. Uyezve, kuteerera uye kuramba kurapwa, rufu anogona kuitika kubva zvose zvaigara pressurization kana chirwere uye chirwere chakakura kumwoyo.

Cushing kuti Syndrome: Zviratidzo.

The kupfuura unoshamisa kuoneka symptomatic chirwere zvinoshamisa kuwedzera uremu muviri, kunyanya mubhokisi, chiso uye dumbu. Izvi anokonzerwa predominance kuti cortisol mumuviri, uye kemikari ichi chinozivikanwa kusimudzira mafuta okuchengetera. Uye Muviri womunhu zvachose disproportionate, kureva, maoko nemakumbo pamusoro mudumbu uye chipfuva mamiriro sokuti zvikuru mutete. Mukuwedzera pane maitiro ano kuti Cushing kuti urwere, kubva paumbwe mafuta matanga pamutsipa uye mapfudzi. chiso murwere zvinooneka wakatenderera, mune zvimwe zviitiko, ganda reddens.

Cortisol kuchambokanganisa mapuroteni ganda thins nemidziyo ropa, zvinoita kuti chitarisiko rupawo uye tatamuka mucherechedzo womuviri, nokuti ganda rinova nyore kufurirwa zvimwewo zvinoitika. Nokuda wakawedzera uremu uye murombo hatchability mvura kubva muviri pavarwere vane yakasimba akaona mumatenhere makumbo. Sezvingatarisirwa, pane kupfupika mweya, unoraramisa tinakidzwe ari kurova kwehana, uye izvi zvose achabatsirwa kunonyengedza vangadikitira. Mukadzi kurwara chirwere ichi chinogona kuzivikanwa nokusimbaradza bvudzi kumeso, saka chero abrasion kana akaputswa kunogona kuva dambudziko chairo, sezvo kupodzwa kwenguva refu.

Zvinofanira kurangarirwa kuti hosha kunooneka zvakananga kwekuoma pfupa uye tsandanyama basa. Nokuda Zvakaitwa kemikari cortisol murwere anonzwa kusimba muviri wose, pane rokutsanya pereutomlyaemost.

Cushing kuti Syndrome: Treatment.

Modern vanachiremba kuti kunenge pakukura hosha anosarudzwa dzakananga nzira kurapwa. Cushing kuti chirwere chinogona kukurirwa kana nokushandisa zvinodhaka, nemwaranzi kurapa, kuvhiyiwa, kana kubviswa zvomukati rakakwana, kazhinji kubva adrenal shwanu.