Corinfar. Mirayiridzo yokushandisa

"Corinfar" ane antagonist calcium, i.e. izvozvo kunoita kuti kurwadziwa kuve kupinda pakati Ca2 + kupinda tsandanyama muchitokisi (cardiomyocyte), mwoyo nemidziyo ropa kubva intercellular nzvimbo. Saka, zvinoderedza wevasungwa calcium ions. Somugumisiro wokukudza peripheral, coronary arteries uye arterioles (nyoro tsinga). Mahwendefa ane kuita nguva refu, ndakataura vasodilating basa.

Medicine "Corinfar" anogadzirwa muchimiro kumativi biconvex mahwendefa zvinenge zvakazara yero firimu unhani. Rimwe hwendefa rine kushingaira fuma - nifedipine (synthesized artificially kubva dihydropyridine) - 10 MG. Ebetsero zvinhu, Hwendefa zvekupfakira akashandisa lactose monohydrate, povidone K25, mbatatisi starch, microcrystalline cellulose, magnesium stearate. "Corinfar" inotengeswa atorwa pamwe Maronda akasiyana nhatu (Mahwendefa 10) kana murima magirazi hombodo dzemvura 50 uye 100 mahwendefa.

In zvirwere zvakadai angina, BP (kuramba BP), varwere vari ushandiswe "Corinfar". Mirayiridzo zvokushandisa wakavhomorwa muna Russian. All ruzivo inobatsira kwete chete nokuda nevashandi vezveutano uye vanachiremba asiwo varwere, sezvo zvichabatsira kunzwisisa chiremba agadzwa, uyewo kuchinja pamuviri, inova mugumisiro matambudziko chezvinodhaka.

Zvinozivikanwa kuti mishonga nokuita kuzopedza (pasina kuderedza Absorção de Água yezviri fuma - nifedipine), kana pakudya kuti "Corinfar". Mirayiridzo kushandisa vanokurudzirwa kuita kudaro (asina mvura) pashure zvokudya uye tikanwa zvinwiwa zvakawanda. Nguva uye dose (kureva, kurapwa) vanosarudzwa nomumwe uye ushandiswe nachiremba. Iva nechokwadi kuti kufungawo aikanganiswa corinfar nekuomarara chirwere. Varwere vakwegura uye vaya vanotambura zvikuru concomitant cerebrovascular chirwere, kuderedza dose.

Kutanga 10 MG pamusoro nifedipine (kana 1 piritsi kaviri kana katatu pazuva) kutora "Corinfar". Mirayiridzo yokushandisa anobvumira zvishoma nezvishoma kuwedzera uwandu husingakuvadzi 2 Mahwendefa kana 20 MG kamwe kana kaviri pazuva. Maximum daily dose hakufaniri kupfuura 4, kana 40 Mahwendefa MG. In zvinokosha neBP (neBP), zvavakabvumirana avhareji zuva dose kunofanira 1 pokunyorera kana 10 MG (kukurukurwa nifedipine) maviri katatu pazuva. Kuti awane zvaaida kunotoda Chaizvoizvo, dose waakaudzwa nachiremba anogona ngazviwedzerwe 40 MG (sezvo nifedipine) pazuva, kutorwa kusvika 2 nguva. Pakati nzira mbiri corinfar pa zviviri kana zvitatu-muchirugu chinangwa, nguva penguva inofanira kuva maawa anenge mana.

Mune dzimwe zvirwere, kwete varumbidzwa "Corinfar". Mirayiridzo kushandiswa contra rinoratidza kwayo arterial hypotension, cardiogenic kuvhunduka, pakaparara, chirwere chemwoyo, mune varwere zvakakomba kutsemuka stenosis, kusagadzikana angina, chenjera myocardial infarction (muvhiki ina dzokutanga), pamwe nokushanda rifampicin. Panewo contraindications lactation mukati I trimester hypersensitivity kuti nifedipine kana ebetsero ingredients.

Special hanya chinodiwa hypertrophic obstructive cardiomyopathy, mitral vharafu stenosis, sinus vanorwara chirwere, zvikuru tachycardia kana bradycardia, hypovolemia, akaipa neBP, myocardial infarction pamwe rworuboshwe ventricular kukundikana, yakanyanya cerebrovascular zvirwere. Uyewo renal uye chiropa kukundikana, nemudumbu mhingaidzo, renal dialysis, munguva II uye III trimesters pamuviri vasati makore 18, vachitsigira Beta-blockers, digoxin.

The gadziriro ine raidudzwa antihypertensive uye antianginal nomugumisiro kuramba kushanda nokuda kunonoka chiito yezviri fuma nazyvetsya "Corinfar kutadzisa". Manual rine mashoko nyanzvi utano uye varwere. The kushingaira wemafuta zvinodhaka riri nyore kunyura kubva nemudumbu. The kuchirapa nezvinozoitika kwete kupfuura maminitsi 15 pashure zvinodhaka kutarisira. Muviri zvinoriumba "corinfar" anowanika mune chiropa nokuda hydrolyzation uye oxidation. The muviri kuti nifedipine yakabereka basa yeimwe. Matafura "Corinfar" zvikurukuru nokuda itsvo, asiwo faeces.