"Captopril". Mirayiridzo yokushandisa

"Captopril» (captopril) - mushonga kungova boka angiotensin rokutendeutsa enzayemu FIs (ACE inhibitor). Munyika dzakawanda kupatsanura kwegadziriro zvinodhaka "Captopril" ndiyo kunyoresa bumbiro C09AA01. gadziriro mushonga chakaita zvokugadzirwa "Captopril" zvichiitirwa tikarega BP Akaroromesawo paumbwe oligopeptide kemikari (vakawana kubva angiotensin I angiotensin II), zvinoita kuti kuderera kwokugadzirwa maererano adrenal cortex kemikari mineralokortikosteroidnogo - aldosterone.

Kune akawanda dzaishandiswa mazita vagadziri akasiyana pave pasi iyo "Captopril". Kushandiswa nerimwe zvizivikanwe Guide rinotsanangura chimiro uye kusunungura chipimo chemushonga (kazhinji mahwendefa 6.25 MG, 12,5 MG, 25 MG, 50 MG, 100 MG). "Une Pharmaceuticals" mugadziri - "Angiopril 25" Mahwendefa. "Vokhard Limited" - "acetyl". Nyika guru mishonga prdktsii "Bristol-Myers Squibb" anozadza pamusika mahwendefa "Capoten". The Russian kambani "Akrikhin" kunobereka "Capoten". Hwendefa pasi "Captopril" vanozivikanwa anobudiswa dzakawanda yemakambani: "Elfa" (Russia), "hexane" (Germany), "Krka" (Slovenia) "Promed kunze kwenyika" (Russia), "Rompharm" (Russia). The American kambani "Ai-CN Pharmaceuticals" kunobereka "Katopil" mapiritsi. Mukusarudza Pharmaceutical Company muGreece "Medokemi" - "Rilkapton". Hungarian mishonga fekitari "Aegis" - Tenziomin mahwendefa. Cypriot kambani "Remedika-Minneks" - "Epsitron".

Doctors mishonga "captopril" monotherapy nezvibereko vanoramba BP (neBP). The chinodhaka inoshandiswa pakurapa chirwere siyana congestive mwoyo kukundikana, kana (pashure infarction), kuruboshwe ventricular basa. Zvinonzi nachiremba pakurapa chirwere cheshuga nephropathy, kuitika tikafunga chirwere cheshuga wokutanga mhando. Nepakati hypotensive zvazviri, sezvo dzimwe ACE FIs inopa anyatsoona kuderera BP. Muzviitiko zvizhinji hafu chipimo chemushonga pakati kufadza akashivirira dose zvinodhaka Zvaringana. Ichienzaniswa nedzimwe mishonga, akadai hydrochlorothiazide, zvishoma nemishonga, rinopa "Captopril". Mirayiridzo dzokushandisa anorondedzera chipimo chemushonga ake chaiwo.

Kuti dzikurukure hypotensive "Captopril" kushanda ikashandiswa pamwe nemamwe zvinodhaka: diuretics (diuretics - hydrochlorothiazide), kana karusiyamu gwara blockers (karusiyamu mhandu ne raidudzwa vasodilator matanho - verapomil, nifedipine nevamwe). Chete nokuda kuongorora, uye inobva zera uye mukuru ezvinhu muviri, chiremba (akabatana nevamwe zvinodhaka kana monotherapy kosi) ibasa "Captopril". Mirayiridzo kushandiswa kwezvinodhaka kunofanira kudzidzwa nenzira murwere, asi kushandura pachavo chipimo chemushonga kwavo kudzima kosi chairayirwa chiremba, kana hakufaniri kuzvidzora medicate. Zvikasadaro, anogona kutungamirira dzakakomba migumisiro yakaipa.

Chiremba anogadza wacho zvinodhaka dosing zvaiitwa. Kazhinji neawa pamberi zvokudya inokurudzirwa kutora "Captopril". Kushandisa zvinodhaka vanofanira kugara, pane imwe chete nguva. Kana neBP "Captopril" kazhinji basa 25 MG (kaviri pazuva). Naizvozvo dose anogona ngazviwedzerwe zvishoma nezvishoma kusvikira zvinozoita kunokwanisika. For mwero BP kwake yakawedzera kusvika 50 MG (kaviri pazuva), uye ari chakakomba chimiro chirwere zvinodhaka kungava kuti katatu pazuva ne50 MG. Panyaya iyi, nezuva dose haafaniri kupfuudza 150 MG. All kuchinja izvi yaifanira chipimo chemushonga ushandiswe nachiremba. Chirwere mwoyo nokukundikana uye vaitire "captopril" , Chipimo chemushonga kutangira 6.25 MG kusvikira katatu pazuva. Zvadaro, dose ichi chinogona kuwedzera zvishoma nezvishoma, asi hapana kupfuura zuva 150 MG. Varwere vakwegura uye varwere havachanyatsogoni renal mashandiro nokungwarira zvikuru vakagadza "Captopril". Mirayiridzo kushandiswa kwezvinodhaka chine ruzivo pamusoro contraindications uye zvichiita yematambudziko kuti murwere havafaniri kukanganwa kuti kuramba kuongorora avo ezvinhu. Kana zvakakodzera, "Captopril" akatorwa pamwe thiazide diuretics yakatevedzana (hydrochlorothiazide, chlorothiazide), kana loop diuretics (semuenzaniso, furasemid).

Mashoko ari munyaya ino hakutsivi mazano ezvokurapa.