Intestinal metaplasia mudumbu: zviratidzo, kurapwa. Squamous metaplasia - a ...

Vanhu vakawanda vari chirwere nezvirwere zvakadai gastric intestinal metaplasia, iyo inozivikanwa nokuva degeneration of gastric epithelium iri intestinal. Hydrochloric asidhi anogadzirwa masero parietal kurega kuita ayo basa, nokudaro akatanga kutambura zvomudumbu nhengo uye muviri anonetseka.

Chinoitika munhu ari chiitiko zvirwere zvakadaro anonzi kuti ngozi, asi isingarapiki. Kana pane masero mudumbu zvinoitika kubereka kuti muura masero, zviri sechinhu precancerous ezvinhu. Kunyange kurapa iyi uye zvinokwanisika, asi panguva yepamusoro siyana pane murombo chaizvo fungidziro.

Chii intestinal metaplasia?

Ichi chirwere umo gastric mucosa munyama inotsiviwa masero intestinal. Kokutanga chirwere akarondedzerwa makore anopfuura 100 akapfuura Professor Kupfer. zvokurwara Izvi unowanzosangana kunokanganisa vakwegura. Maererano nenhamba, 80% wevarwere vane chirwere gastritis uye duodenal urikanwi.

In vanhu utano, asi zvinyama kufukidza madziro mudumbu, zvose vari yoku-. Kana kukuvara kunoitika, masero otanga nesimba, zvichiguma imwe kunowedzera kutama kwavo uye kuzoita muchitokisi kuvandudzwa. Izvi pavarwere vane chirwere gastritis achishungurudzika, nekuti icho gastric shwanu anomiswa kuita mabasa avo, zvichiita kuti paumbwe metaplasia.

Mhando zvirwere

Metaplasia mudumbu iri nezvezvikwata zviviri:

• bowel diki (rakakwana, vakasimba);
• Colonic (kukwana, saibva).

The akura chimiro kunoratidzwa kuvapo masero rinogona chete kuva ura diki: sulfamutsiny, chikamu ichocho ndicho chinoita, wakanwa enterocytes. Zvisinei, chikuru chinhu kuti inosimbisa izvi mhando zvokurwara vanoonekwa Paneth masero. Dumbu rinenge kutanga zvifanane duku ura sezvo marongerwo uye dzichipfekeka zvivako.

Saibva metaplasia mudumbu kunoratidzwa vasingadzoreki kuibvisa uye kugadzira mumasero gastric uye epithelium kakawanda hunomiririrwa muura masero.

Unofanira kuziva kuti gastric kenza muna 94% nyaya dzakaonekwa kukwana metaplasia. ezvinhu akadaro anonzi kuva precancerous, wononoka kurapwa zvinonzi zvinouraya.

Uyezve, zvinokosha kuziva kunyanya squamous metaplasia. Ngationgororei izvozvo zvizere.

Chii squamous metaplasia?

A Zvinoitwa zvokurwara ino kuti panzvimbo dzose epithelium stratified squamous rukoko aumbwa. At paro, zviri inofanira kuzvitsinhanisa masero vakura kusiyaniswa zvikuru zvishoma vakasimba. Ekupedzisira vane unyanzvi zvikuru kuchinja, sezvo kazhinji kuva chero sero mhando kuti ave kuramba siyana kukuvadza zvinhu.

Somuenzaniso, epithelial squamous metaplasia pamusoro gastric mudumbu nemaronda anobatsira sunungura kukuvadza kunoita makemikari nekusazvidzora acid. Kana irritant yabviswa, kuti zvinyama anodzokera zvarakanga ezvinhu.

Zvisinei, sechiratidzo pathological muitiro mhando kwakadaro metaplasia hapasi kudzvinyirira zvinhu. Izvi zvinotungamirira pakuti saibva masero, kuedza kugadzirisa, tanga kuunganidza vazhinji Gene kunotouraya uye havachakwanisi kudzora nokupesana kwavo, akatendeuka kupinda kenza substrate.

Nei kuitika metaplasia?

chirwere ichi anovandudza nokuda kwezvikonzero zvinotevera:

• kuzvimba mudumbu lining kwakakonzerwa zvakasiyana-siyana;
• chisingaperi kuzvimba yegurokuro tishu;
• kakawanda mupfungwa;
• hormone zvirwere;
• kutsamwa ari nemudumbu;
• gastritis, ichiyerera kwenguva refu.

sei chirwere kuratidza?

Ihosha pachako hakuna nzira kunoratidza pacharo, uye zvose hwokufananidzira metaplasia zviratidzo chokuita nezvirwere yakabatsira kuti ayo budiriro. Idzi dzinosanganisira:

• svoto;
• kurasikirwa havi;
• achirwadza kurwadziwa epigastric nharaunda.

Inosimudzira acidity mudumbu achabatsirwa iine acid reflux, "nzara" marwadzo, anokwanisa kukura usiku. Kana intestinal metaplasia pamwe akandwe yegurokuro pamusoro gastric mukati, kuonekwe kurutsa uye shungu pamuromo.

Diagnostics

Kuziva chimiro chirwere, pavaiita histological kuzviongorora. Zviri kuti muviri womunhu vanobva zvidimbu duku zvinyama uye zviri kudzidzwa. Nzira fenzi kana masero epithelial inonzi biopsy. nzira iyi nechirwere anonzi kunodiwa kana paine kunyumwira kuti malignancy.

Kuti tizive ukuru kuvadza nemudumbu, kumwe kutsvakurudza rinoitwa pachishandiswa endoscopic michina. Zvinyama pasi nokufungira, akasvibiswa chaiwo pendi kuti hakukuvadzi chose kuvanhu muviri. Kana masero akakuvadzwa, wana chaiwo ruvara, uye ndaona pasi maikorosikopu inogona zvakajeka.

Features kurapwa

Kana chirwere intestinal metaplasia, kurapwa chirwere ichi unotakurwa mishonga uye expeditious netsika. Murwere anofanira vakanyorwa kuti gastroenterologist.

mishonga kurapwa

nzira iyi yokurapa inoshandiswa zvinotevera nyaya:

• kubvisa gastroesophageal reflux chirwere - chirwere dzinoratidzwa enderana kukanda akakwidzwa yegurokuro acidic zviri mudumbu, sezvo zvinokanganisa mucosa;
• kudzivirira benign anomera;
• kudzvinyirira gastric secretion.

Nokuti kurapwa nachiremba wenyu mishonga zvinotevera zvinodhaka:

• Purotoni kupomba FIs - zvinodhaka ano kuti kuderedza gastric acidity. "Omeprazole" kuvabata, "Rabeprazole" "Pantoprazole".
• Antacids ( "Fosfalyugel", "Maalox") - mishonga inoita neutralization pamusoro hydrochloric acid.
• H2 - histamine blockers ( "Ranitidine", "cimetidine") - antisecretory zvinodhaka.
• Gastroprotectives - kana chichiwedzera acidity mudumbu, vanobatsira kudzivisa kuparadzwa mucosa.

kuvhiya kupindira

Kana kuchinja mabatiro hakuiti yakanaka mugumisiro, ipapo chiremba ringavakurudzira kuvhiyiwa. Sei yakapedza metaplasia? Izvi zvinoitwa kushandisa endoscopic michina chaiyo kurerutsa mwero kukuvara, uye ichi anonzi zvishoma invasive kuvhiyiwa. Kana zvakakodzera, ukama nzvimbo yakanga yabviswa zvachose. Nzira yakadaro yokurapa kanoverengeka kunoderedza mukana carcinogenic idzodzo.

dziviriro

Kuti udzivise panowanikwa zvirwere zvakadai intestinal metaplasia, unofanira kuita zvinoenderana matanho.

Zvakakosha kudzivisa chimiro kunetseka, chokwadi chimwe kune mikana yakawanda yokukurudzira. Iva nechokwadi kuti zvakazara kuzorora.

Kuomerera utsanana nemitemo muviri. Gastric intestinal metaplasia hakusi chete utachiona Helicobacter, asi zvimwe zvirwere. Uyezve, kana utsanana dzemunharaunda vari akambokanganiswa, mukana wokusvika chikafu chepfu, kuti yatichawana kutsvinyira gastric mucosa.

Unofanirawo kuramba zvinovaka muviri. Muchiitiko ichi zvakakosha chose kusiya zvakadaro namakemikari Sevamiririri, sezvo carbonated rinonwa, Spicy, yakanatswa, vava zvokudya, zvikafu. Zvakanakisisa kusanganisira kudya kwenyu zvokudya, akapfuma Mishonga faibha. Zvinogona siyana bota, miriwo, miriwo, michero, chingwa chinobva rose gorosi.

mhedziso

Saka, takaona kuti metaplasia kwakadaro. Ichi chirwere ngozi chinogona kukonzera kenza mudumbu. nenguva nyaya kuna chiremba uye kuchengetwa ose anodiwa kunenge chete anogona kuderedza kana kubva atanga rokuparadza kwendangariro.